المؤلفون: Tamer Coskun, Kyle W. Sloop, Corina Loghin, Jorge Alsina-Fernandez, Shweta Urva, Krister B. Bokvist, Xuewei Cui, Daniel A. Briere, Over Cabrera, William C. Roell, Uma Kuchibhotla, Julie S. Moyers, Charles T. Benson, Ruth E. Gimeno, David A. D'Alessio, Axel Haupt

المصدر: Molecular Metabolism, Vol 18, Iss , Pp 3-14 (2018)

مصطلحات موضوعية: Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2212877818309001Test; https://doaj.org/toc/2212-8778Test

الوصول الحر: https://doaj.org/article/e80aeca8145a4ac5b361969b75b1dc5eTest

المؤلفون: Francis S. Willard (10306561), David B. Wainscott (10306564), Aaron D. Showalter (10306567), Cynthia Stutsman (10306570), Wenzhen Ma (546079), Guemalli R. Cardona (10306573), Richard W. Zink (2232373), Christopher M. Corkins (10306576), Qi Chen (144168), Nathan Yumibe (2527282), Javier Agejas (1581091), Graham R. Cumming (4376143), José Miguel Minguez (10306579), Alma Jiménez (1816990), Ana I. Mateo (3024924), Ana M. Castaño (10306582), Daniel A. Briere (10306585), Kyle W. Sloop (10306588), Ana B. Bueno (1451155)

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Physiology, Pharmacology, Immunology, Developmental Biology, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, LSN 3318839 increases, β- arrestin recruitment, glucose-dependent insulin secretion, LSN 3318839 support, GLP -1R potentiation, GLP -1R, Ex vivo experiments show, LSN 3318839

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_an_Orally_Efficacious_Positive_Allosteric_Modulator_of_the_Glucagon-like_Peptide_1_Receptor/14219779Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c00029.s001Test

المؤلفون: Marlena M. Holter, Margot K. Chirikjian, Daniel A. Briere, Adriano Maida, Kyle W. Sloop, Kristina Schoonjans, Bethany P. Cummings

المصدر: Nutrients; Volume 12; Issue 7; Pages: 2124

مصطلحات موضوعية: hepatocyte, TGR5, glucose regulation

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Nutritional Epidemiology; https://dx.doi.org/10.3390/nu12072124Test

الإتاحة: https://doi.org/10.3390/nu12072124Test

المؤلفون: Hua V. Lin, Jingru Wang, Jie Wang, Weiji Li, Xuesong Wang, James T. Alston, Melissa K. Thomas, Daniel A. Briere, Samreen K. Syed, Alexander M. Efanov

المصدر: Molecular Metabolism, Vol 11, Iss , Pp 205-211 (2018)

مصطلحات موضوعية: Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2212877818301224Test; https://doaj.org/toc/2212-8778Test

الوصول الحر: https://doaj.org/article/51a98efe956c4a619df0f0a69c4863d8Test

المؤلفون: Daniel A. Briere, David B. Wainscott, José Miguel Minguez, Cynthia Stutsman, Qi Chen, Ana B. Bueno, Alma Jiménez, Kyle W. Sloop, Ana I. Mateo, Guemalli R. Cardona, Wenzhen Ma, Aaron D. Showalter, Graham R Cumming, Ana M. Castaño, Francis S. Willard, Richard W. Zink, Javier Agejas, Nathan Yumibe, Christopher M Corkins

المصدر: Journal of Medicinal Chemistry. 64:3439-3448

مصطلحات موضوعية: Blood Glucose, Models, Molecular, Agonist, endocrine system, Allosteric modulator, medicine.drug_class, Metabolite, Administration, Oral, Pharmacology, 01 natural sciences, Glucagon-Like Peptide-1 Receptor, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, chemistry.chemical_compound, Allosteric Regulation, Drug Discovery, medicine, Animals, Humans, Hypoglycemic Agents, Receptor, 030304 developmental biology, 0303 health sciences, Chemistry, digestive, oral, and skin physiology, Long-term potentiation, Ligand (biochemistry), Glucagon-like peptide-1, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Molecular Medicine, hormones, hormone substitutes, and hormone antagonists, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f48ac2debed19ca46755aefd201e2e9Test
https://doi.org/10.1021/acs.jmedchem.1c00029Test

المؤلفون: Tamer Coskun, Shweta Urva, William C. Roell, Hongchang Qu, Corina Loghin, Julie S. Moyers, Libbey S. O’Farrell, Daniel A. Briere, Kyle W. Sloop, Melissa K. Thomas, Valentina Pirro, David B. Wainscott, Francis S. Willard, Matthew Abernathy, LaRonda Morford, Yu Du, Charles Benson, Ruth E. Gimeno, Axel Haupt, Zvonko Milicevic

المصدر: Cell metabolism. 34(9)

مصطلحات موضوعية: Physiology, Body Weight, Mice, Obese, Cell Biology, Gastric Inhibitory Polypeptide, Glycemic Control, Glucagon, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, Mice, Weight Loss, Receptors, Glucagon, Animals, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0680405a26fc0854e942b2516c1cf62aTest
https://pubmed.ncbi.nlm.nih.gov/35985340Test

المؤلفون: Shweta Urva, Emily C Beebe, Michael A. Nauck, Charles Benson, Xuewei Cui, Tamer Coskun, Corina Loghin, Libbey S. O’Farrell, Daniel A. Briere, Axel Haupt

المصدر: Diabetes, Obesity and Metabolism. 22:1886-1891

مصطلحات موضوعية: Agonist, endocrine system, medicine.medical_specialty, Gastric emptying, medicine.drug_class, business.industry, Endocrinology, Diabetes and Metabolism, Semaglutide, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Glucagon-like peptide-1, Acetaminophen, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, Internal Medicine, medicine, Dulaglutide, business, Receptor, Glucagon-like peptide 1 receptor, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::98a07224445c496000bf7c6feab8566eTest
https://doi.org/10.1111/dom.14110Test

المؤلفون: Ricardo J. Samms, Richard Cosgrove, Brandy M. Snider, Ellen C. Furber, Brian A. Droz, Daniel A. Briere, James Dunbar, Mridula Dogra, Jorge Alsina-Fernandez, Tito Borner, Bart C. De Jonghe, Matthew R. Hayes, Tamer Coskun, Kyle W. Sloop, Paul J. Emmerson, Minrong Ai

المصدر: Diabetes. 71(7)

مصطلحات موضوعية: Mice, Endocrinology, Diabetes and Metabolism, Internal Medicine, Animals, Nausea, Peptide YY, Anti-Obesity Agents, Obesity, Receptors, Gastrointestinal Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f9dd85499b95673bebf33dad3347bdTest
https://pubmed.ncbi.nlm.nih.gov/35499381Test

المؤلفون: Liyun Ding, Matthew P. Coghlan, Ellen P.S. Conceição Furber, Jorge Alsina-Fernandez, Kyle W. Sloop, Brian A. Droz, Mridula Dogra, Annie M. Long, Michael E. Christe, Tamer Coskun, Ruth E. Gimeno, Xiaoping Ruan, Jill A. Willency, William C. Roell, Debra L. Konkol, Adrienne K. Holland, Ricardo J. Samms, Jessica L. Friedrich, Libbey S. O’Farrell, Valentina Pirro, Over Cabrera, Daniel A. Briere, Richard Cosgrove, Samantha Wojnicki, Kyla A.L. Collins, Julie S. Moyers, Yanzhu Lin, Christine C. Cheng

المصدر: J Clin Invest

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.medical_specialty, medicine.drug_class, Adipose Tissue, White, medicine.medical_treatment, Gastric Inhibitory Polypeptide, White adipose tissue, Type 2 diabetes, Glucagon-Like Peptide-1 Receptor, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Internal medicine, Diabetes mellitus, Brown adipose tissue, medicine, Animals, Obesity, Sensitization, Mice, Knockout, business.industry, Insulin, Body Weight, General Medicine, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, 030220 oncology & carcinogenesis, Insulin Resistance, business, Amino Acids, Branched-Chain, hormones, hormone substitutes, and hormone antagonists, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4281cb2d7c4426d2de7cba245f46e9Test
https://doi.org/10.1172/jci146353Test

المؤلفون: Daniel A Briere, Xiaoping Ruan, Christine C Cheng, Angela M Siesky, Thomas E Fitch, Carmen Dominguez, Sonia Gutierrez Sanfeliciano, Carlos Montero, Chen S Suen, Yanping Xu, Tamer Coskun, M Dodson Michael

المصدر: PLoS ONE, Vol 10, Iss 8, p e0136873 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC4551797?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/0e3cad23ebd14667ac97596b703b1f92Test