المؤلفون: Siyuan Chen, Xiawei Wei, Manni Wang, Yuquan Wei

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3935-3949 (2021)

مصطلحات موضوعية: Senescence, Paclitaxel, DNA repair, NHEJ, non homologous end joining, medicine.medical_treatment, LCLC, large-cell carcinoma, RM1-950, Chemosensitization, DDR, DNA damage response, chemistry.chemical_compound, Non-small cell lung cancer, DNA-PK, DNA-dependent protein kinase, NSCLC, non-small cell lung cancer, medicine, Cytotoxic T cell, General Pharmacology, Toxicology and Pharmaceutics, Lung cancer, Adverse effect, DSB, DNA double-strand breaks, Etoposide, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, Chemotherapy, business.industry, LADC, lung adenocarcinoma, medicine.disease, LSCC, lung squamous cell carcinoma, respiratory tract diseases, M3814, dsDNA, double strand DNA, chemistry, DNA-dependent protein kinase, Cancer research, Original Article, Cell senescence, Therapeutics. Pharmacology, HR, homologous recombination, business, IHC, immunohistochemistry, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48576014833ff0883918307b9873dc5eTest
http://europepmc.org/articles/PMC8727896Test

المؤلفون: Ana Clara Azevedo-Pouly, Olivia G. Moffett, Lyle Burdine, David K Harrison, Marie Schluterman Burdine, Zachary J Waldrip, Samuel G. Mackintosh, Aaron J. Storey

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Transcription, Genetic, T-Lymphocytes, Cell, CK II, casein kinase II, DNA-Activated Protein Kinase, Mice, SCID, Lymphocyte Activation, Biochemistry, Jurkat Cells, Mice, Inbred NOD, Transcription (biology), transcription factor, DNA-PKcs, IEG, immediate early response gene, Mice, Inbred BALB C, early growth response protein 1 (EGR1), Protein Stability, TCR, T cell receptor, Chemistry, phosphoproteomics, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, NHEJ, nonhomologous end joining, Cytokines, biological phenomena, cell phenomena, and immunity, Research Article, endocrine system, T cell, Mutation, Missense, T cells, enzyme inhibitor, EGR1, immediate early response gene (IEG), Immune system, medicine, Animals, Humans, DNA-dependent protein kinase catalytic subunit (DNA-PKcs), DSB, double-strand break, IFN, interferon, Kinase activity, Protein kinase A, Egr1, early growth response protein 1, Molecular Biology, Transcription factor, phorbol ester, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, Early Growth Response Protein 1, IL2, KO, knockout, TMT, tandem mass tag, Cell Biology, WT, wild-type, IL, interleukin, enzymes and coenzymes (carbohydrates)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982295e7ef521d03fb988c5e6673f339Test
https://doi.org/10.1101/2021.06.04.446996Test

المؤلفون: Edyta Heropolitanska Pliszka, Małgorzata Pac, Mateusz Maciejczyk, Bożena Mikołuć, Barbara Pietrucha, Halina Car, Radosław Motkowski

المصدر: Redox Biology, Vol 11, Iss, Pp 375-383 (2017)
Redox Biology

مصطلحات موضوعية: Prx 3, mitochondrial peroxiredoxin 3, DNA Repair, LCLs, lymphoblastoid cell lines, Fe, iron, Review Article, Biochemistry, Antioxidants, Nijmegen breakage syndrome (NBS), Glx, glyoxal, Bloom syndrome, mtETC, mitochondrial electron transport chain, lcsh:QH301-705.5, Cu, copper, 8-OHdG, 8-hydroxy-2-deoxyguanosine, ox-LDL, oxidised low-density lipoprotein, food and beverages, DS, Down Syndrome, UA, uric acid, Lipoproteins, LDL, CS, Cockayne Syndrome, Poly(ADP-ribose) Polymerases, lcsh:Medicine (General), Bloom Syndrome, GSH-Px, glutathione peroxidase, G6PD, glucose-6 phosphate dehydrogenase, DNA damage, TOP1mt, mitochondrial topoisomerase I, FA, Fanconi anaemia, mTOR, mammalian target of rapamycin, XP, Xeroderma pigmentosum, DDR, DNA damage response, 03 medical and health sciences, Oxidative damage, Humans, HO, heme oxygenase, BS, Bloom syndrome, NOX4, NADPH oxidase 4, Nijmegen Breakage Syndrome, Ataxia-telangiectasia (A-T), DNA-PKcs, DNA-dependent protein kinase catalytic subunit, MDA, malondialdehyde, XO, xanthine oxidase, GSSG, oxidised glutathione, medicine.disease, LWMA, low molecular weight antioxidants, 030104 developmental biology, DSBs, double strand breaks, Ataxia-telangiectasia, AA, ascorbic acid, GSSG-R, glutathione reductase, CAT, catalase, HR, homologous recombination, PARP, Poly (ADP-ribose) polymerases, Reactive Oxygen Species, Nijmegen breakage syndrome, 0301 basic medicine, MGlx, methylglyoxal, GSH, reduced glutathione, PDTC, ammonium pyrrolidinedithiocarbamate, Clinical Biochemistry, Mitochondrion, medicine.disease_cause, ALA, α-lipolic acid, HGS, Hutchinson-Gilford syndrome, LOX, lipoxygenase, t-butyl-OOH, tert-Butyl-hydroperoxide, CBS, chromosomal breakage syndromes, NAC, N-acetyl-L-cysteine, lcsh:R5-920, NADPH oxidase, GPx, glutathione peroxidase, biology, mROS, mitochondrial reactive oxygen species, Zn, zinc, Mitochondria, AOA3, ataxia with oculomotor apraxia type 3, PKC-δ, protein kinase C, X/XO, xanthine/xanthine oxidase, NADPH Oxidase 4, Signal Transduction, Premature aging, Bloom syndrome (BS), AOS, antioxidant defense systems, NAD+, oxidised nicotinamide adenine dinucleotide, Se, selenium, Ataxia Telangiectasia, ROS, reactive oxygen species, SOD, superoxide dismutase, GST, glutathione-S-transferase, medicine, Q10, ubiquinone, IR, ionising radiation, Organic Chemistry, A-T, Ataxia-telangiectasia, mtDNA, mitochondrial DNA, POLG, polymerase gamma, Oxidative Stress, NBS, Nijmegen breakage syndrome, Gene Expression Regulation, lcsh:Biology (General), ATM, Ataxia Telangiectasia Mutated gene, NOX2, NADPH oxidase 2, biology.protein, Cancer research, WS, Werner syndrome (WS), SMG-1, suppressor with morphological effect on genitalia family member, ATR, ATM and Rad3-related, Oxidative stress, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67542494f0fd02567e8cbe6a4d847ca2Test

المؤلفون: Kyung Jong Lee, Keiko Morotomi-Yano, Debabrata Saha, Yu Fen Lin, Jingxin Sun, Benjamin P C Chen, Zeng Fu Shang

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 4, Pp 329-338 (2015)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: G2 Phase, Cancer Research, Mitosis, Cell Cycle Proteins, Polo-like kinase, DNA-Activated Protein Kinase, Protein Serine-Threonine Kinases, lcsh:RC254-282, Article, DNA-Dependent Protein Kinase Catalytic Subunit, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Proto-Oncogene Proteins, CDC2 Protein Kinase, Humans, ASK1, DNA Breaks, Double-Stranded, DNA-PKcs, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, 030304 developmental biology, 0303 health sciences, Cyclin-dependent kinase 1, biology, Pteridines, Cyclin-dependent kinase 2, Nuclear Proteins, HCT116 Cells, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cyclin-Dependent Kinases, Cell biology, enzymes and coenzymes (carbohydrates), PBD, polo box domain, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Plk1, polo-like kinase 1, Casein kinase 2, biological phenomena, cell phenomena, and immunity, Cell Division, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1c176c264d47b11a61771c3c7ec4f9Test
http://www.sciencedirect.com/science/article/pii/S1476558615000305Test

المؤلفون: Yasutomo Yutoku, Manabu Koike, Aki Koike

المصدر: FEBS Open Bio

مصطلحات موضوعية: Cell death, Programmed cell death, Ku80, EYFP, enhanced yellow fluorescent protein, Cell growth, Cytotoxicity, fungi, Hamster, DSBs, DNA double-strand breaks, DNA repair protein XRCC4, Biology, GFP, EGFP, enhanced green fluorescent protein, Molecular biology, Article, General Biochemistry, Genetics and Molecular Biology, Green fluorescent protein, ECFP, enhanced cyan fluorescent protein, Ku, NHEJ, nonhomologous end-joining, XRCC4, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, DNA-PKcs, GFP, green fluorescent protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44d50505f0ff4f3d782e080921da847Test
https://repo.qst.go.jp/records/46558Test

المؤلفون: Veerle De Wever, Pauline Douglas, Nick A. Morrice, Ruiqiong Ye, Laura Trinkle-Mulcahy, Katheryn Meek, Jessica A. Neal, Susan P. Lees-Miller

المصدر: Bioscience Reports, Vol 34, Iss 3, p e00113 (2014)
Bioscience Reports

مصطلحات موضوعية: lcsh:Life, lcsh:QR1-502, Cell Cycle Proteins, Chk2, checkpoint kinase 2, Polo-like kinase, DNA-Activated Protein Kinase, Mitogen-activated protein kinase kinase, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, lcsh:Microbiology, DNA-Dependent Protein Kinase Catalytic Subunit, Phosphoprotein Phosphatases, PP6, protein phosphatase 6, Phosphorylation, DNA-PKcs, GFP, green fluorescent protein, ATM, ataxia telangiectasia mutated, biology, Chemistry, Nuclear Proteins, MEM, Minimum Essential Medium Alpha, FHA, forkhead associated, Cell biology, NHEJ, non-homologous end-joining, PIPES, 1,4-piperazinediethanesulfonic acid, midbody, Casein kinase 2, biological phenomena, cell phenomena, and immunity, DSB, DNA double-strand break, Biophysics, S6, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins, Humans, PLK1, polo-like kinase-1, Molecular Biology, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, protein phosphatase 6, mitosis, Original Paper, MAP kinase kinase kinase, polo-like protein kinase 1, Cyclin-dependent kinase 2, Cell Biology, Checkpoint Kinase 2, enzymes and coenzymes (carbohydrates), lcsh:QH501-531, DNA-dependent protein kinase, siRNA, small interfering RNA, TPX2, targeting protein for Xklp2, biology.protein, IR, ionizing radiation, Cyclin-dependent kinase 9, HeLa Cells, DAPI, 4′,6-diamidino-2-phenylindole

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c140f77f60ae358707cf137d4f7a28Test
http://www.bioscirep.org/bsr/034/e113/bsr034e113.htmTest

المؤلفون: James Z. Chen, Richard Henderson, John L. Rubinstein, Nikolaus Grigorieff, Lori A. Passmore, Phoebe L. Stewart, R. Anthony Crowther, Peter B. Rosenthal, Luciano Ciccarelli, Shaoxia Chen

المصدر: Journal of Molecular Biology

مصطلحات موضوعية: Rotavirus, Cryo-electron microscopy, Analytical chemistry, Image processing, Molecular physics, Article, law.invention, cryoEM, electron cryomicroscopy, Structural Biology, law, Yeasts, FAS, fatty acid synthetase, Image Processing, Computer-Assisted, Animals, Molecular Biology, TPPP, tilt-pair parameter plot, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, EMDB, Electron Microscopy Data Bank, Adenosine Triphosphatases, Range (particle radiation), EM, electron microscopy, electron microscopy, Orientation (computer vision), Chemistry, Resolution (electron density), Cryoelectron Microscopy, 3D, three-dimensional, Virion, DLP, double-layered particle, beta-Galactosidase, PDH, pyruvate dehydrogenase, Tilt (optics), beam-induced specimen motion, structure validation, radiation damage, CAV, chicken anemia virus, Particle, Cattle, Electron microscope, particle orientation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784f7feb3c0dc4ebe5feb94dbaca12ceTest