يعرض 1 - 10 نتائج من 13,121 نتيجة بحث عن '"DNA TOPOISOMERASES"', وقت الاستعلام: 1.34s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Olympic gels formed through catenation of dsDNA rings regulated by topoisomerase II: A coarse-grained model.

    المؤلفون: Zhang, Zhongyan1,2 (AUTHOR), Zhao, Wenbo1 (AUTHOR), Cheng, Zhiyuan1 (AUTHOR), Zhang, Guojie3 (AUTHOR), Liu, Hong1,4 (AUTHOR) guojie.zhang@gzhu.edu.cn

    المصدر: Journal of Chemical Physics. 2/7/2024, Vol. 160 Issue 5, p1-13. 13p.

    مصطلحات موضوعية: *DNA topoisomerase II, *DNA topoisomerases, *DNA topoisomerase I, *TOPOLOGY


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  2. 2
    دورية أكاديمية
    Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn‐BNP)‐Coupled Metagenomics.

    المؤلفون: Wang, Zongqiang1 (AUTHOR), Kasper, Amanda1 (AUTHOR), Takahashi, Mai2 (AUTHOR), Morales Amador, Adrian1 (AUTHOR), Bhattacharjee, Abir1 (AUTHOR), Kan, Jingbo1 (AUTHOR), Hernandez, Yozen1 (AUTHOR), Ternei, Melinda1 (AUTHOR), Brady, Sean F.1 (AUTHOR) sbrady@rockefeller.edu

    المصدر: Angewandte Chemie. 4/22/2024, Vol. 136 Issue 17, p1-6. 6p.

    مصطلحات موضوعية: *NATURAL products, *DNA topoisomerases, *DNA topoisomerase I, *METAGENOMICS, *HOLLOW fibers, *CHEMICAL synthesis, *IRINOTECAN


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  3. 3
    دورية أكاديمية
    Discovery of new Schiff bases of the disalicylic acid scaffold as DNA gyrase and topoisomerase IV inhibitors endowed with antibacterial properties.

    المؤلفون: Al-Wahaibi, Lamya H., Mahmoud, Mohamed A., Alzahrani, Hayat Ali, Abou-Zied, Hesham A., Gomaa, Hesham A. M., Youssif, Bahaa G. M., Brase, Stefan, Rabea, Safwat M., Amorim, Juliana, Baki, Vijaya Bhaskar, Wu, Chunli

    المصدر: Frontiers in Chemistry; 2024, p1-21, 21p

    مصطلحات موضوعية: DNA topoisomerase II, SCHIFF bases, DNA topoisomerases, ANTIBACTERIAL agents, SALICYLIC acid

    النص الكامل

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  4. 4
    دورية أكاديمية
    Role of Supercoiling and Topoisomerases in DNA Knotting.

    المؤلفون: Cebrián, Jorge, Martínez-Robles, María-Luisa, Martínez, Victor, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B., Fernández-Nestosa, María-José

    المصدر: DNA (2673-8856); Jun2024, Vol. 4 Issue 2, p170-179, 10p

    مصطلحات موضوعية: DNA topoisomerases, ELECTROPHORESIS, ESCHERICHIA coli, DNA replication, CHLOROQUINE, PLASMIDS


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  5. 5
    دورية أكاديمية
    Extensive Bioinformatics Analyses Reveal a Phylogenetically Conserved Winged Helix (WH) Domain (Zτ) of Topoisomerase IIα, Elucidating Its Very High Affinity for Left-Handed Z-DNA and Suggesting Novel Putative Functions.

    المؤلفون: Bartas, Martin1 (AUTHOR) martin.bartas@osu.cz, Slychko, Kristyna1 (AUTHOR), Červeň, Jiří1 (AUTHOR), Pečinka, Petr1 (AUTHOR), Arndt-Jovin, Donna J.2 (AUTHOR), Jovin, Thomas M.2 (AUTHOR) martin.bartas@osu.cz

    المصدر: International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 13, p10740. 27p.

    مصطلحات موضوعية: *DNA topoisomerase I, *DNA topoisomerases, *DNA topoisomerase II, *DRUG discovery, *RNA polymerases, *DNA polymerases, *HUMAN embryology, *MOLECULAR recognition

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  6. 6
    دورية أكاديمية
    Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.

    المؤلفون: Keller, Josephine Geertsen1 (AUTHOR), Petersen, Kamilla Vandsø2 (AUTHOR), Mizielinski, Karol1 (AUTHOR), Thiesen, Celine2 (AUTHOR), Bjergbæk, Lotte2 (AUTHOR), Reguera, Rosa M.3 (AUTHOR), Pérez-Pertejo, Yolanda3 (AUTHOR), Balaña-Fouce, Rafael3 (AUTHOR), Trejo, Angela4 (AUTHOR), Masdeu, Carme4 (AUTHOR), Alonso, Concepcion4 (AUTHOR), Knudsen, Birgitta R.1,2 (AUTHOR), Tesauro, Cinzia1 (AUTHOR) ct@vpcir.com

    المصدر: Pharmaceuticals (14248247). May2023, Vol. 16 Issue 5, p657. 14p.

    مصطلحات موضوعية: *DNA topoisomerase I, *DNA topoisomerases, *MEDICAL screening, *MYCOBACTERIUM smegmatis, *MONKEYPOX, *LEISHMANIA donovani, *MEDICAL protocols, *LEISHMANIA

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  7. 7
    دورية أكاديمية
    New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization

    المؤلفون: Mohammed, Hamada HH, El-Hafeez, Amer Ali Abd, Ebeid, Kareem, Mekkawy, Aml I, Abourehab, Mohammed AS, Wafa, Emad I, Alhaj-Suliman, Suhaila O, Salem, Aliasger K, Ghosh, Pradipta, Abuo-Rahma, Gamal El-Din A, Hayallah, Alaa M, Abbas, Samar H

    المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry. 37(1)

    مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Cancer, Colo-Rectal Cancer, Digestive Diseases, Antineoplastic Agents, Caco-2 Cells, Cell Line, Tumor, Cell Proliferation, Chalcone, Chalcones, Ciprofloxacin, DNA Damage, DNA Topoisomerases, Type I, DNA Topoisomerases, Type II, Doxorubicin, Drug Screening Assays, Antitumor, Humans, Molecular Structure, Polymerization, Structure-Activity Relationship, Triazoles, Tubulin, Click synthesis, ciprofloxacin, chalcone, cytotoxicity, HCT116 cells, topoisomerase I and II inhibitors, tubulin polymerisation inhibition, DNA damage, Biochemistry and Cell Biology, Medicinal & Biomolecular Chemistry, Medicinal and biomolecular chemistry

    وصف الملف: application/pdf

    الوصول الحر: https://escholarship.org/uc/item/4008934rTest

    View record in eScholarship

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  8. 8
    دورية أكاديمية
    StaR Is a Positive Regulator of Topoisomerase I Activity Involved in Supercoiling Maintenance in Streptococcus pneumoniae.

    المؤلفون: de Vasconcelos Junior, Antonio A.1 (AUTHOR), Tirado-Vélez, Jose M.1 (AUTHOR), Martín-Galiano, Antonio J.2 (AUTHOR), Megias, Diego3 (AUTHOR), Ferrándiz, María-José1 (AUTHOR), Hernández, Pablo4 (AUTHOR), Amblar, Mónica1 (AUTHOR) mamblar@isciii.es, de la Campa, Adela G.1,5 (AUTHOR) mamblar@isciii.es

    المصدر: International Journal of Molecular Sciences. Mar2023, Vol. 24 Issue 6, p5973. 21p.

    مصطلحات موضوعية: *DNA topoisomerase I, *DNA topoisomerases, *DNA topoisomerase II, *STREPTOCOCCUS pneumoniae, *PROTEIN-protein interactions, *CONFOCAL microscopy

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  9. 9
    دورية أكاديمية
    A novel gyrase inhibitor from toxin-antitoxin system expressed by Staphylococcus aureus.

    المؤلفون: Fuminori Kato1 fkyato@hiroshima-u.ac.jp, Yoshihiro Yamaguchi2, Keiko Inouye3, Koichi Matsuo4, Yojiro Ishida3 inouye@cabm.rutgers.edu, Masayori Inouye3

    المصدر: FEBS Journal. Mar2023, Vol. 290 Issue 6, p1502-1518. 17p.

    مصطلحات موضوعية: *DNA topoisomerase II, *DNA topoisomerases, *DNA synthesis, *ESCHERICHIA coli, *BACTERIAL toxins, *RNA synthesis, *DNA topoisomerase I

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  10. 10
    دورية أكاديمية
    Unraveling topoisomerase IA gate dynamics in presence of PPEF and its preclinical evaluation against multidrug-resistant pathogens.

    المؤلفون: Maurya, Vikas1 (AUTHOR), Singh, Raja1 (AUTHOR), Singh, Reman Kumar2 (AUTHOR), Pandey, Stuti1 (AUTHOR), Yadav, Pooja1 (AUTHOR), Parashar, Palak1 (AUTHOR), Gaind, Rajni3 (AUTHOR), Dubey, Kshatresh Dutta4 (AUTHOR), Naresh Patwari, G.2 (AUTHOR), Tandon, Vibha1 (AUTHOR) vtandon@mail.jnu.ac.in

    المصدر: Communications Biology. 2/18/2023, Vol. 6 Issue 1, p1-20. 20p.

    مصطلحات موضوعية: *DNA topoisomerase I, *DNA topoisomerases, *GRAM-negative bacteria, *BACTERIAL enzymes, *ESCHERICHIA coli, *BINDING energy, *METHICILLIN-resistant staphylococcus aureus

    النص الكامل

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