نتائج البحث - "DMF, dimethylformamide"

المساهمون: Nassour, Hassan, Hoang, Tuan Anh, Martin, Ryan D, Dallagnol, Juliana C C, Billard, Étienne, Létourneau, Myriam, Novellino, Ettore, Carotenuto, Alfonso, Allen, Bruce G, Tanny, Jason C, Fournier, Alain, Hébert, Terence E, Chatenet, David

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Protein Conformation, alpha-Helical, Peptide Hormones, G-protein-coupled receptors, UT, urotensin II receptor, Ligands, Biochemistry, 7TMR, 7-transmembrane receptor, RP-HPLC, reverse-phase high-performance liquid chromatography, Receptors, G-Protein-Coupled, chemistry.chemical_compound, HEK293 Cell, lipidated peptide, Receptor, Chemistry, HEK 293 cells, human embryonic kidney 293 cells, lipidated peptides, Intracellular Signaling Peptides and Proteins, allosteric modulator, Fmoc, fluorenylmethyloxycarbamate, Cell biology, DCM, dichloromethane, Peptide, Phosphorylation, allosteric modulators, DMF, dimethylformamide, Human, Research Article, Signal Transduction, Cell signaling, G-protein-coupled receptor, pepducin, Allosteric regulation, Ligand, Urotensin-II receptor, DQF-COSY, double-quantum filtered correlated spectroscopy, UII, urotensin II, BOP, (benzotriazol-1-yloxy)tris(dimethylamino) phosphonium hexafluorophosphate, Allosteric Regulation, NOESY, nuclear Overhauser enhancement spectroscopy, pepducins, DPC, dodecylphosphocholine, Humans, urotensin II receptor, BRET, bioluminescence resonance energy transfer, NMR, nuclear magnetic resonance, Molecular Biology, MALDI-TOF, matrix-assisted laser desorption/ionization–time of flight, G protein-coupled receptor, GPCR, G-protein-coupled receptor, Cell Proliferation, HEK 293 cells, URP, urotensin II-related peptide, Cell Biology, CHO cells, Chinese hamster ovary cells, TOCSY, total correlated spectroscopy, HEK293 Cells, Intracellular Signaling Peptides and Protein, Peptide Hormone, TSP, 3-(trimethylsilanyl)propionic acid, cellular signaling, DIEA, N,N-diisopropylethylamine, Urotensin-II, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fe3abca6a81eb53384d871fe901993Test
http://europepmc.org/articles/PMC8424217Test

5

Cardiac myosin-binding protein C interaction with actin is inhibited by compounds identified in a high-throughput fluorescence lifetime screen

المؤلفون: Thomas A. Bunch, Piyali Guhathakurta, Andrew R. Thompson, Brett A. Colson, David D. Thomas, Victoria C. Lepak, Rhye Samuel Kanassatega, Anna Wilson

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Time Factors, HCM, hypertrophic cardiomyopathy, AF568, Alexa Fluor 568, library of pharmacologically active compounds (LOPAC), Biosensing Techniques, cardiac myosin-binding protein C (cMyBP-C), Biochemistry, IAEDANS, 5-((((2-iodoacetyl)amino)ethyl)amino)naphtalene-1-sulfonic acid, chemistry.chemical_compound, cMyBP-C, cardiac myosin-binding protein C, high-throughput screening (HTS), DO, donor only, TR-FRET, time-resolved fluorescence energy transfer, Myosin, Fluorescence Resonance Energy Transfer, DA, donor plus acceptor, TMR, tetramethylrhodamine, DWR, direct waveform recording, DCM, dilated cardiomyopathy, AF546, Alexa Fluor 546, SE, standard errors, phosphorylation, FLTPR, fluorescence lifetime plate reader, ITC, isothermal titration calorimetry, P/A, proline/alanine-rich linker between domains C0 and C1, HTS, high-throughput screen, TR-F, time-resolved fluorescence, protein kinase A (PKA), contractile proteins, LOPAC, library of pharmacologically active compounds, Rabbits, DMF, dimethylformamide, actin, Kd, dissociation constant, Protein Binding, Research Article, Sarcomeres, cardiac muscle, site-directed spectroscopy, TCEP, tris(2-carboxyethyl)phosphine, C0-C2, N-terminal fragment of cMyBP-C comprised of C0-P/A-C1-M-C2 domains and linkers, TPA, transient phosphorescence anisotropy, macromolecular substances, Calorimetry, ATA, aurintricarboxylic acid, Filamentous actin, Fluorescence, SD, standard deviations, 03 medical and health sciences, Aurintricarboxylic acid, fluorescence lifetime, Animals, Humans, Binding site, Molecular Biology, Actin, M-ABB, MOPS-actin binding buffer, 030102 biochemistry & molecular biology, M, M-domain, phosphorylatable linker between C1 and C2, Ligand binding assay, Binding protein, Myocardium, Isothermal titration calorimetry, Cell Biology, G-actin, globular actin, ErIA, erythrosine iodoacetamide phosphorescent dye, Actins, High-Throughput Screening Assays, F-actin, filamentous actin, 030104 developmental biology, chemistry, DTT, dithiothreitol, FMAL, fluorescein-5-maleimide, DMSO, dimethylsulphoxide, Bmax, maximum molar binding ratio, Biophysics, BSA, bovine serum albumin, PKA, protein kinase A, Carrier Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e8b63a383fc7d22dea35788b29aa60Test
https://pubmed.ncbi.nlm.nih.gov/34052227Test

6

Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents

المؤلفون: Viktor Kelemen, Lieve Naesens, Son Le Thai, Pál Herczegh, Annelies Stevaert, Evelien Vanderlinden, Gyula Batta, Magdolna Csávás, Anikó Borbás, Zsolt Szűcs, Erzsébet Rőth

المصدر: European Journal of Medicinal Chemistry

مصطلحات موضوعية: Maleimide, 0301 basic medicine, SI, selectivity index, chemistry.chemical_compound, Drug Discovery, MCC, minimum cytotoxic concentration, logP, logarithm of the partition coefficient, Influenza virus inhibitor, Molecular Structure, Galp, galactopyranose, Chemistry, Teicoplanin, General Medicine, NA, neuraminidase, Glycopeptide, DCM, dichloromethane, HIV, human immunodeficiency virus, CPE, cytopathic effect, Influenza A virus, Lipophilicity, Click chemistry, DMF, dimethylformamide, tosyl, p-toluenesulfonyl, medicine.drug, Cell Survival, Stereochemistry, medicine.drug_class, SARS-CoV, severe acute respiratory syndrome coronavirus, 030106 microbiology, Et3N, triethylamine, MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, Microbial Sensitivity Tests, Glycopeptide antibiotic, Sulfonamide, SEM, standard error of the mean, Antiviral Agents, Article, Cell Line, Structure-Activity Relationship, 03 medical and health sciences, medicine, Humans, Structure–activity relationship, Cell Proliferation, Pharmacology, TLC, thin layer chromatography, Dose-Response Relationship, Drug, Lipoglycopeptide, Organic Chemistry, PMB, p-methoxybenzyl, Coronavirus, Influenza B virus, M2, Matrix-2, 030104 developmental biology, TEG, tetraethylene glycol, Ph, phenyl, MDCK, Madin−Darby Canine Kidney, Linker, HA, hemagglutinin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1f990905c13f90aa1cedded5f0d6faTest
https://doi.org/10.1016/j.ejmech.2018.08.058Test

7

Continuous microfluidic synthesis of zirconium-based UiO-67 using a coiled flow invertor reactor

المؤلفون: Tom Bailey, Merwyn Pinto, Nicole Hondow, Ke-Jun Wu

المصدر: MethodsX
MethodsX, Vol 8, Iss, Pp 101246-(2021)

مصطلحات موضوعية: Materials science, Science, Clinical Biochemistry, Microfluidics, SBU, secondary building unit, chemistry.chemical_element, Fraction (chemistry), 010501 environmental sciences, 7. Clean energy, 01 natural sciences, Catalysis, 03 medical and health sciences, Crystallinity, Continuous Microfluidic Synthesis of Zirconium-based UiO-67 using a coiled flow invertor reactor, SEM, scanning electron microscopy, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, Zirconium, Coiled flow inverter reactor (CFIR), PXRD, powder X-Ray Diffraction, BPDC, biphenyl-4,4-dicarboxylic acid, Method Article, Residence time distribution, Medical Laboratory Technology, RTD, residence time distribution, chemistry, Chemical engineering, CFIR, coiled flow inverter reactor, UiO, universitetet i Oslo, Particle-size distribution, MOFs, Metal organic frameworks, Particle size, DMF, dimethylformamide, Continuous synthesis, Metal-organic frameworks (MOFs)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e15b2a96047e074d3f6bf1787b3af62Test
https://eprints.whiterose.ac.uk/173582/1/1-s2.0-S221501612100039X-main.pdfTest

8

Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators

المؤلفون: Anders Gunnarsson, Arjan Snijder, Christian Ottmann, Saleha Patel, Leonardo De Maria, Luc Brunsveld, Claire C. Munier, Carol MacKintosh, Karl Edman, Lisa Wissler, Perry Matthew, Marianna Longo

المساهمون: Chemical Biology, ICMS Core

المصدر: Journal of Biological Chemistry, 296:100551. American Society for Biochemistry and Molecular Biology Inc.
'Journal of Biological Chemistry ', vol: 296, pages: 100551-1-100551-15 (2021)
The Journal of Biological Chemistry

مصطلحات موضوعية: Threonine, 0301 basic medicine, MINK1, misshapen-like kinase 1, Biochemistry, LBD, ligand-binding domain, Glucocorticoid receptor, MINK1, HATU, 1-[bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate, glucocorticoid receptor, nuclear receptor, ROCK1, Phosphorylation, Kinase, Chemistry, TBST, tris-buffered saline with Polysorbate 20, DCM, dichloromethane, Cell biology, ROCK1, Rho-associated coiled-coil containing protein kinase 1, DMF, dimethylformamide, FP, fluorescence polarization, Protein Binding, Research Article, Transcriptional Activation, MINK1 kinase, TCEP, tris(2-carboxyethyl)phosphine, SPR, surface plasmon resonance, Protein Serine-Threonine Kinases, 03 medical and health sciences, Receptors, Glucocorticoid, PDB, Protein Data Bank, DIPEA, N,N-diisopropylethylamine, Humans, NTD, N-terminal domain, NMP, N-methyl-2-pyrrolidone, Protein kinase A, Molecular Biology, Transcription factor, GR, glucocorticoid receptor, 030102 biochemistry & molecular biology, 14-3-3 protein, ERα, estrogen receptor α, Cell Biology, KPSI, kilopounds per square inch, HEK293 Cells, protein–protein interaction, 030104 developmental biology, 14-3-3 Proteins, Gene Expression Regulation, Nuclear receptor, DBD, DNA-binding domain, Mutation, ERRγ, estrogen-related receptor γ, Co-IP, co-immunoprecipitation