المؤلفون: Margarita Gerou, Benjamin A. Hall, Scott P. Allen, Kathrin Meyer, Pamela J. Shaw, Ryan Woof, Jessica Allsop, Stephen J. Kolb

المصدر: Neurobiology of Aging

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, AGEs, advanced glycation end products, SOD1, superoxide dismutase 1, DHAP, dihydroxyacetone phosphate, chemistry.chemical_compound, 0302 clinical medicine, FALS, familial amyotrophic lateral sclerosis, PGM, phosphoglucomutase, Glycolysis, Amyotrophic lateral sclerosis, SALS, sporadic amyotrophic lateral sclerosis, Glycogen, General Neuroscience, Middle Aged, ALS, amyotrophic lateral sclerosis, Aging, ALS, iNPC, induced neuronal progenitor cell, Disease Progression, Ketoglutaric Acids, Female, medicine.drug, Adult, medicine.medical_specialty, C9ORF72, chromosome 9 open reading frame 72, ETC, electron transport chain, Citric Acid Cycle, TCA, tricarboxylic acid, Context (language use), Biology, Article, 03 medical and health sciences, iPSC, induced pluripotent stem cells, ROS, reactive oxygen species, Internal medicine, medicine, Humans, LDHA, lactate dehydrogenase A, Progenitor cell, Inosine, Aged, G3P, glyceraldehyde 3-phosphate, GP, glycogen phosphorylase, NADH, nicotinamide adenine dinucleotide, reduced form, Amyotrophic Lateral Sclerosis, ChREBP, carbohydrate response element binding protein, Metabolism, Fibroblasts, iAstrocytes, induced astrocytes, medicine.disease, NAD, mtDNA, mitochondrial DNA, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, chemistry, Neurology (clinical), Geriatrics and Gerontology, Age of onset, TDP-43, TAR DNA-binding protein 43, Energy Metabolism, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa322bad33369b41380c3947538e1343Test
http://europepmc.org/articles/PMC8346650Test

المؤلفون: Pimchai Chaiyen, Jirawat Tantipisit, Asweena Binlaeh, Litavadee Chuaboon, Juthamas Jaroensuk, Somchart Maenpuen, Penchit Chitnumsub, Ruchanok Tinikul, Aritsara Jaruwat, Jittima Phonbuppha, Pratchaya Watthaisong, Narin Lawan

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: structure–function, p-hydroxyphenylacetate degradation pathway, Acinetobacter baumannii, Enzyme complex, PMSF, phenyl methane sulfonyl fluoride, QM/MM, quantum mechanics/molecular mechanics, DHAP, dihydroxyacetone phosphate, SSA, succinic semialdehyde, Crystallography, X-Ray, Biochemistry, HKHD, 4-hydroxy-2-ketoheptane-1,7-dioate, MW, molecular weight, Substrate Specificity, FPLC, fast protein liquid chromatography, LC-ESI-QTOF-MS, liquid chromatography-electrospray ionization-quadrupole-time-of-flight mass spectrometer, NaCl, sodium chloride, Aldol reaction, stereospecificity, Catalytic Domain, Fructose-Bisphosphate Aldolase, Enzyme Stability, Tm, melting temperature, PPA, propionaldehyde, biology, solvent-tolerant enzyme, LDH, lactate dehydrogenase, Chemistry, MD, molecular dynamics, Enzyme structure, HOPA, 4-hydroxy-2-oxopentanoate, Zinc, (NH4)2SO4, ammonium sulfate, PYR, pyruvate, metal-dependent enzyme, Research Article, crystal structure, HNO3, nitric acid, SEC, size-exclusion chromatography, ICP-OES, inductively coupled plasma-optical emission spectrometry, Stereochemistry, (4R)-KDGal, (4R)-2-keto-3-deoxy-D-galactonate, stereoselectivity, enzyme catalysis, Catalysis, Enzyme catalysis, Stereospecificity, (4S)-KDGlu, (4S)-2-keto-3-deoxy-D-gluconate, Bacterial Proteins, PDB, Protein Data Bank, NADH, the reduced β-nicotinamide adenine dinucleotide, thermostable enzyme, Molecular Biology, M2+, divalent meatl ion, PEI, polyethyleneimine, MPD, 2-methyl-2,4-pentanediol, Aldolase A, EGTA, ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid, HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid, Cell Biology, AbHpaI, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase from Acinetobacter baumannii, HBA, 4-hydroxybenzaldehyde, EcHpaI, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase from Escherichia coli, Biocatalysis, DTT, dithiothreitol, biology.protein, Aldol condensation, BSA, bovine serum albumin, EDTA, ethylenediaminetetraacetatic acid, Calcium, OAA, oxaloacetate, pyruvate-specific Class II metal aldolase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ec40387511a3835e3f518a5fda0050Test
http://europepmc.org/articles/PMC8560999Test

المؤلفون: Eunsook S. Jin, Craig R. Malloy, Min H. Lee

المصدر: Metabolism Open, Vol 9, Iss, Pp 100086-(2021)
Metabolism Open

مصطلحات موضوعية: 3HP, 3-hydroxypropionate, Metabolite, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Hamster, ACC, acetyl-CoA carboxylase, DHAP, dihydroxyacetone phosphate, lcsh:Physiology, lcsh:Biochemistry, GK, glycerol kinase, chemistry.chemical_compound, PCC, propionyl-CoA carboxylase, Ketogenesis, Glycerol, lcsh:QD415-436, α-kG, α-ketoglutarate, Glu, glutamate, 3HPA, 3-hydroxypropionaldehyde, lcsh:QP1-981, β-HB, β-hydroxybutyrate, Acetyl-CoA, G3P, glycerol 3-phosphate, Gluconeogenesis, GlyDH, glycerol dehydrogenase, Metabolism, Aldehyde dehydrogenase, PDH, pyruvate dehydrogenase, Original Research Paper, Citric acid cycle, ALDH, aldehyde dehydrogenase, 3-Hydroxypropionate, chemistry, Biochemistry, GA3P, glyceraldehyde 3-phosphate, 1,3PDO, 1,3-propanediol, 1,3-Propanediol, Oxidative metabolism, OAA, oxaloacetate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675290128f116ea040e00c4c3e286fbeTest
http://www.sciencedirect.com/science/article/pii/S2589936821000104Test

المؤلفون: Marcel Imber, Agnieszka J. Pietrzyk-Brzezinska, Haike Antelmann

المصدر: Redox Biology
Redox Biology, Vol 20, Iss, Pp 130-145 (2019)

مصطلحات موضوعية: Antioxidant, medicine.medical_treatment, MetE, methionine synthase, Review Article, Mal, malate, protein-SSB, BSH protein mixed disulfide, DHAP, dihydroxyacetone phosphate, Biochemistry, LMW, low molecular weight, 0302 clinical medicine, Met, methionine, GSH, glutathione, GlxA/B, glyoxalases A and B, lcsh:QH301-705.5, HTA, hemithioacetal, roGFP2, redox-sensitive green fluorescent protein, RSS, reactive sulfur species, GlcN, glucoseamine, pKa, negative base-10 logarithm of the acid dissociation constant, GapDH, glycolytic glyceraldehyde 3-phosphate dehydrogenase, MSH, mycothiol, OHP, organic hydroperoxide, MRSA, methicillin-resistant Staphylococcus aureus, OhrR, organic hydroperoxide repressor, GuaB, inosine-5-monophosphate dehydrogenases, FeS, iron-sulfur, Protein S-thiolation, Gram-positive bacteria, 3. Good health, Grx, glutaredoxin, FA, formaldehyde, Mca, mycothiol-S-conjugate amidase, lcsh:Medicine (General), MSONH2, MSH sulfinamide, CoASSH, CoASH persulfide, MgsA, methylglyoxal synthase, 03 medical and health sciences, Structure-Activity Relationship, NADH, nicotinamide adenine dinucleotide, CHP, cumene hydroperoxide, HED, hydroxyethyl disulfide, Humans, INH, isoniazid, LC-MS/MS, liquid chromatography tandem mass spectrometry, Pathogenic bacteria, CA-MRSA, community acquired MRSA, MT, metallothionein, EGT, ergothioneine, Gst, GSH-S-transferases, MsrA/B, methionine sulfoxide reductase A/B, 030104 developmental biology, chemistry, DTT, dithiothreitol, MG, methylglyoxal, MST, mycothiol-S-transferase, 030217 neurology & neurosurgery, 0301 basic medicine, Cys, cysteine, Clinical Biochemistry, Mrx1, mycoredoxin1, Bacillithiol, medicine.disease_cause, Bca, BSH S-conjugate amidase, Corynebacterium glutamicum, chemistry.chemical_compound, Trx, thioredoxin, MetSO, methionine sulfoxide, PpaC, inorganic pyrophosphatase, lcsh:R5-920, Glucosamine, biology, Mycobacterium smegmatis, Glycopeptides, SarZ, redox-sensing virulence regulator, AcCys, acetyl cysteine, Brx, bacilliredoxin, H2O2, hydrogen peroxide, GlcNAc, N-acetyl glucoseamine, BSSB, oxidized bacillithiol disulfide, NFC, nitrofuranylcalanolide, Oxidation-Reduction, Bst, BSH-S-transferases, TrxR, thioredoxin reductase, Mtb, Mycobacterium tuberculosis, PPP, pentose phosphate pathway, Mycothiol, Models, Biological, GSSG, oxidized glutathione disulfide, RNS, reactive nitrogen species, ROS, reactive oxygen species, AhpE, membrane-associated peroxidase, BshB, deacetylase producing GlcN-Mal, PDB, Protein Data Bank, YpdA, NADPH-dependent flavin oxidoreductase, medicine, Ins, myoinositol, CoASH, coenzymeA, Animals, BshC, cysteine ligase for BSH biosynthesis, MSNO, S-nitrosomycothiol, Cysteine, Sulfhydryl Compounds, Ac, acetyl, BshA, glycosyltransferase for GlcNAc-Mal biosynthesis, HOCl, sodium hypochlorite, Organic Chemistry, NADPH, nicotinamide adenine dinucleotide phosphate, STRING, Search Tool for the Retrieval of Interacting Genes/Proteins, biology.organism_classification, AldA, aldehyde dehydrogenase A, BSH, bacillithiol, lcsh:Biology (General), Protein Processing, Post-Translational, Bacteria, RES, reactive electrophilic species, Inositol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f489c6dc700b786fd74ac141fe7a87Test
http://europepmc.org/articles/PMC6178380Test

المؤلفون: Chengmeng Jin, Qiangrong Pan, Xun Hu, Xiaobing Zhu

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, F6P, fructose 6-phosphate, DHAP, dihydroxyacetone phosphate, Biochemistry, NC, negative control, chemistry.chemical_compound, cell metabolism, Neoplasms, Warburg Effect, Oncologic, RNA, Small Interfering, Phosphoglycerate kinase 1, Glyceraldehyde 3-phosphate dehydrogenase, PGAM, phosphoglycerate mutase, education.field_of_study, biology, GAPDH-SA, GAPDH specific activity, LDH, lactate dehydrogenase, GAPDH, Glyceraldehyde-3-Phosphate Dehydrogenases, glycolysis, Glc, glucose, Warburg effect, TPI, triose phosphate isomerase, GA3P, glyceraldehyde 3-phosphate, flux control, Gibbs free energy, Oxidation-Reduction, Research Article, FBP, fructose 1,6-bisphosphate, G6P, glucose 6-phosphate, 03 medical and health sciences, stomatognathic system, FBS, fetal bovine serum, G6PDH, glucose-6-phosphate dehydrogenase, Cell Line, Tumor, PGI, phosphohexose isomerase, PGK, phosphoglycerate kinase, Humans, IA, iodoacetate, education, Molecular Biology, GAPDH-AA, GAPDH actual activity, Dihydroxyacetone phosphate, UPLC, ultra performance liquid chromatography, Hexokinase, 030102 biochemistry & molecular biology, PEP, phosphoenolpyruvate, Cell Biology, HK, hexokinase, Pyr, pyruvate, 030104 developmental biology, Glucose, chemistry, Glucose 6-phosphate, Anaerobic glycolysis, PK, pyruvate kinase, biology.protein, cancer cells, WE, Warburg effect, Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), Pyruvate kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d332adf7ec310c14c988541e3e3aa008Test
https://pubmed.ncbi.nlm.nih.gov/33545174Test

المؤلفون: Héctor, Acosta, Richard, Burchmore, Christina, Naula, Melisa, Gualdrón-López, Ender, Quintero-Troconis, Ana J, Cáceres, Paul A M, Michels, Juan Luis, Concepción, Wilfredo, Quiñones

المصدر: Molecular and Biochemical Parasitology

مصطلحات موضوعية: Proteomics, GALK, galactokinase, Glyc3P, glycerol 3-phosphate, Trypanosoma cruzi, Protozoan Proteins, GPDH, glycerol-3-phosphate dehydrogenase, GDH, glutamate dehydrogenase, HGPRT, hypo-xanthine-guanine phosphoribosyltransferase, Glycosome, DHAP, dihydroxyacetone phosphate, PMP, peroxisomal membrane protein, GAT, glycosomal ABC transporter, Microbodies, G6P, glucose 6-phosphate, IMPDH, inosine-5′-monophosphate dehydrogenase, Cell fractionation, Article, ADH, alcohol dehydrogenase, PFK, phosphofructokinase, HADH, hydroxyacid dehydrogenase, PPDK, pyruvate phosphate dikinase, SOD, superoxide dismutase, PGK, phosphoglycerate kinase, FBPase, fructose-1,6-bisphosphatase, FH, fumarate hydratase, Chagas Disease, PAS, Per-ARNT-Sim, HMG-CoA, 3-hydroxy-3-methyl-glutaryl Coenzyme A, ComputingMethodologies_COMPUTERGRAPHICS, Life Cycle Stages, 3PGA, 3-phosphoglycerate, Mass spectrometry, PPP, pentose-phosphate pathway, PEP, phosphoenolpyruvate, MDH, malate dehydrogenase, HK, hexokinase, PEX, peroxin, FRD, fumarate reductase, Metabolism, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, APRT, adenine phosphoribosyltransferase, PEPCK, phosphoenolpyruvate carboxykinase, MCF, mitochondrial carrier family, PPi, inorganic pyrophosphate, ACBP, acyl-CoA-binding protein, PTS, peroxisomal-targeting signal, Glycolysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::0f4916d5902a8e2f6bc792a94e5964a9Test
https://pubmed.ncbi.nlm.nih.gov/30831156Test

المؤلفون: Thorsten Forster, Manu Verma, Tak Yung Man, Megan C. Holmes, Zhenguang Zhang, Natalie Z.M. Homer, Tiina Kipari, Karen E. Chapman, Jonathan R. Seckl

المصدر: Verma, M, Kipari, T, Zhang, Z, Man, T Y, Forster, T, Homer, N Z M, Seckl, J R, Holmes, M C & Chapman, K E 2017, ' 11β-hydroxysteroid dehydrogenase-1 deficiency alters brain energy metabolism in acute systemic inflammation ', Brain, Behavior, and Immunity . https://doi.org/10.1016/j.bbi.2017.11.015Test
Brain, Behavior, and Immunity

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Male, Neutrophils, medicine.medical_treatment, OAA, oxaloacetic acid, SDHA, DHAP, dihydroxyacetone phosphate, Systemic inflammation, Hippocampus, Monocytes, Behavioral Neuroscience, Mice, Glucocorticoid metabolism, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Glycolysis, Illness Behavior, Mice, Knockout, Behavior, Animal, 3PGA, 3-phosphoglyceraldehyde, HPA, hypothalamicpituitary-adrenal, 11β-hydroxysteroid dehydrogenase, 11-DHC, 11-dehydrocorticosterone, 3. Good health, Mitochondria, Cytokine, LPS, lipopolysaccharide, lipids (amino acids, peptides, and proteins), medicine.symptom, Glucocorticoid, hormones, hormone substitutes, and hormone antagonists, medicine.drug, 11β-HSD1, 11β-hydroxysteroid dehydrogenase type-1, medicine.medical_specialty, Immunology, TCA, tricarboxylic acid, Inflammation, Biology, Neuroprotection, Article, 03 medical and health sciences, Internal medicine, medicine, Animals, Endocrine and Autonomic Systems, Energy metabolism, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Anaerobic glycolysis, Corticosterone

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcbfbdd2ee3a67bd429f3d5fdeb6e02Test
https://hdl.handle.net/20.500.11820/87e3bca5-01b4-4b24-9959-af9148236678Test