يعرض 1 - 10 نتائج من 203 نتيجة بحث عن '"D'Arca, Domenico"', وقت الاستعلام: 1.69s تنقيح النتائج
  1. 1
    مؤتمر
    Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer

    المؤلفون: Tagliazucchi, Lorenzo, Piazzi, Manuela, d'Arca, Domenico, Marverti, Gaetano, Moschella Maria Gaetana, Bedeschi, Martina, Tesei, Anna, Passardi, Alessandro, Costi, M Paola

    المساهمون: Tagliazucchi, Lorenzo, Piazzi, Manuela, D'Arca, Domenico, Marverti, Gaetano, Moschella, MARIA GAETANA, Bedeschi, Martina, Tesei, Anna, Passardi, Alessandro, Costi, M Paola

    العلاقة: ispartofbook:XXVIII National Congress of Società Chimica Italiana; XXVIII National Congress of Società Chimica Italiana; https://hdl.handle.net/11380/1337346Test; https://sci2024.orgTest/

    الإتاحة: https://hdl.handle.net/11380/1337346Test
    https://sci2024.orgTest/

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  2. 2
    دورية أكاديمية
    Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth

    المؤلفون: Costantino, Luca, Ferrari, Stefania, Santucci, Matteo, Salo-Ahen, Outi MH, Carosati, Emanuele, Franchini, Silvia, Lauriola, Angela, Pozzi, Cecilia, Trande, Matteo, Gozzi, Gaia, Saxena, Puneet, Cannazza, Giuseppe, Losi, Lorena, Cardinale, Daniela, Venturelli, Alberto, Quotadamo, Antonio, Linciano, Pasquale, Tagliazucchi, Lorenzo, Moschella, Maria Gaetana, Guerrini, Remo, Pacifico, Salvatore, Luciani, Rosaria, Genovese, Filippo, Henrich, Stefan, Alboni, Silvia, Santarem, Nuno, da Silva Cordeiro, Anabela, Giovannetti, Elisa, Peters, Godefridus J, Pinton, Paolo, Rimessi, Alessandro, Cruciani, Gabriele, Stroud, Robert M, Wade, Rebecca C, Mangani, Stefano, Marverti, Gaetano, D'Arca, Domenico, Ponterini, Glauco, Costi, Maria Paola

    مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Cancer, Orphan Drug, Rare Diseases, Biotechnology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Female, Animals, Mice, Humans, Binding Sites, Thymidylate Synthase, Fluorouracil, Ovarian Neoplasms, Enzyme Inhibitors, thymidylate synthase, protein dimer destabilizers, cancer growth inhibition, proteasomal degradation, enzyme dissociative inhibition mechanism, target engagement, Human, biochemistry, cancer biology, chemical biology, human, Biological sciences, Biomedical and clinical sciences, Health sciences

    وصف الملف: application/pdf

    الوصول الحر: https://escholarship.org/uc/item/4vr606hwTest

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  3. 3
    دورية أكاديمية
    Targeting the Interplay of Independent Cellular Pathways and Immunity: A Challenge in Cancer Immunotherapy

    المؤلفون: Lauriola, Angela, Davalli, Pierpaola, Marverti, Gaetano, Santi, Spartaco, Caporali, Andrea, D’Arca, Domenico

    المساهمون: Lauriola, Angela, Davalli, Pierpaola, Marverti, Gaetano, Santi, Spartaco, Caporali, Andrea, D’Arca, Domenico

    مصطلحات موضوعية: immunotherapy, cancer, immunotherapy limitations, immunotherapy challenges

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:001004897500001; volume:15; issue:11; firstpage:1; lastpage:41; numberofpages:41; journal:CANCERS; https://hdl.handle.net/11562/1095426Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85161366800; https://www.mdpi.com/2072-6694/15/11/3009Test

    الإتاحة: https://doi.org/10.3390/cancers15113009Test
    https://hdl.handle.net/11562/1095426Test
    https://www.mdpi.com/2072-6694/15/11/3009Test

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  4. 4
    دورية أكاديمية
    Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library

    المؤلفون: Lauriola, Angela, Uliassi, Elisa, Santucci, Matteo, Bolognesi, Maria Laura, Mor, Marco, Scalvini, Laura, Elisi, Gian Marco, Gozzi, Gaia, Tagliazucchi, Lorenzo, Marverti, Gaetano, Ferrari, Stefania, Losi, Lorena, D'Arca, Domenico, Costi, Maria Paola

    المساهمون: Lauriola, Angela, Uliassi, Elisa, Santucci, Matteo, Bolognesi, Maria Laura, Mor, Marco, Scalvini, Laura, Elisi, Gian Marco, Gozzi, Gaia, Tagliazucchi, Lorenzo, Marverti, Gaetano, Ferrari, Stefania, Losi, Lorena, D'Arca, Domenico, Costi, Maria Paola

    مصطلحات موضوعية: TEAD transcription factor, chemoinformatic, leads repurposing, luciferase assay, p-quinoid derivatives

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35214125; info:eu-repo/semantics/altIdentifier/wos/WOS:000933309500001; volume:14; issue:2; firstpage:391; lastpage:412; numberofpages:22; journal:PHARMACEUTICS; https://hdl.handle.net/11562/1093748Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85124651123

    الإتاحة: https://doi.org/10.3390/pharmaceutics14020391Test
    https://hdl.handle.net/11562/1093748Test

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  5. 5
    دورية أكاديمية
    Telomere Dysfunction Is Associated with Altered DNA Organization in Trichoplein/Tchp/Mitostatin (TpMs) Depleted Cells

    المؤلفون: Lauriola, Angela, Davalli, Pierpaola, Marverti, Gaetano, Caporali, Andrea, Mai, Sabine, D'Arca, Domenico

    المساهمون: Lauriola, Angela, Davalli, Pierpaola, Marverti, Gaetano, Caporali, Andrea, Mai, Sabine, D'Arca, Domenico

    مصطلحات موضوعية: cancer, mitostatin, nuclear architecture, quantitative microscopy, structured illumination microscopy, telomeres

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35884905; info:eu-repo/semantics/altIdentifier/wos/WOS:000831691200001; volume:10; issue:7; firstpage:1; lastpage:14; numberofpages:14; journal:BIOMEDICINES; https://hdl.handle.net/11562/1116978Test

    الإتاحة: https://doi.org/10.3390/biomedicines10071602Test
    https://hdl.handle.net/11562/1116978Test

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  6. 6
    دورية أكاديمية
    Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth

    المؤلفون: Luca, Constantino, Ferrari, Stefania, Santucci, Matteo, Salo-Ahen, Outi MH, Carosati, Emanuele, Franchini, Silvia, Lauriola, Angela, Pozzi, Cecilia, Trande, Matteo, Gaia, Gozzi, Saxena, Puneet, Cannazza, Giuseppe, Losi, Lorena, Cardinale, Daniela, Venturelli, Alberto, Quotadamo, Antonio, Linciano, Pasquale, Lorenzo, Tagliazucchi, Moshella, Maria Gaetana, Guerrini, Remo, Pacifico, Salvatore, Luciani, Rosaria, Genovese, Filippo, Stefan, Henrich, Silvia, Alboni, Santarem, Nuno, Cordeiro-da-Silva, Anabela, Giovannetti, Elisa, Peters, Godefridus, Pinton, Paolo, Rimessi, Alessandro, Cruciani, Gabriele, Stroud, Robert, Wade, Rebecca C., Mangani, Stefano, Marverti, Gaetano, D'Arca, Domenico, Ponterini, Glauco, Costi, Maria Paola

    المصدر: Luca , C , Ferrari , S , Santucci , M , Salo-Ahen , O MH , Carosati , E , Franchini , S , Lauriola , A , Pozzi , C , Trande , M , Gaia , G , Saxena , P , Cannazza , G , Losi , L , Cardinale , D , Venturelli , A , Quotadamo , A , Linciano , P , Lorenzo , T , Moshella , M G , Guerrini , R , Pacifico , S , Luciani , R , Genovese , F , Stefan , H , Silvia ....

    مصطلحات موضوعية: thymidylate synthase, homodimer, protein-protein interface, Anticancer drug resistance, drug discovery, medicinal chemistry, Inhibitor

    وصف الملف: application/pdf

    العلاقة: https://research.abo.fi/en/publications/dce0a05a-89a1-41c0-8492-98a31519865fTest

    الإتاحة: https://doi.org/10.7554/eLife.73862Test
    https://research.abo.fi/en/publications/dce0a05a-89a1-41c0-8492-98a31519865fTest
    https://research.abo.fi/ws/files/49451818/Destabilizers_of_the_thymidylate_synthase.pdfTest
    https://urn.fi/URN:NBN:fi-fe2023022228186Test

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  7. 7
    دورية أكاديمية
    Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting

    المؤلفون: Marverti, Gaetano, Marraccini, Chiara, Martello, Andrea, D'Arca, Domenico, Pacifico, Salvatore, Guerrini, Remo, Spyrakis, Francesca, Gozzi, Gaia, Lauriola, Angela, Santucci, Matteo, Cannazza, Giuseppe, Tagliazucchi, Lorenzo, Cazzato, Addolorata Stefania, Losi, Lorena, Ferrari, Stefania, Ponterini, Glauco, Costi, Maria P

    المساهمون: Marverti, Gaetano, Marraccini, Chiara, Martello, Andrea, D'Arca, Domenico, Pacifico, Salvatore, Guerrini, Remo, Spyrakis, Francesca, Gozzi, Gaia, Lauriola, Angela, Santucci, Matteo, Cannazza, Giuseppe, Tagliazucchi, Lorenzo, Cazzato, Addolorata Stefania, Losi, Lorena, Ferrari, Stefania, Ponterini, Glauco, Costi, Maria P

    مصطلحات موضوعية: Thymidylate Synthase, Cancer, Drug targeting, drug conjugates

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33710891; info:eu-repo/semantics/altIdentifier/wos/WOS:000635440600024; volume:64; issue:6; firstpage:3204; lastpage:3221; numberofpages:18; journal:JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11562/1093746Test

    الإتاحة: https://doi.org/10.1021/acs.jmedchem.0c02107Test
    https://hdl.handle.net/11562/1093746Test

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  8. 8
    دورية أكاديمية
    Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy

    المؤلفون: Martello, Andrea, Lauriola, Angela, Mellis, David, Parish, Elisa, Dawson, John C, Imrie, Lisa, Vidmar, Martina, Gammoh, Noor, Mitić, Tijana, Brittan, Mairi, Mills, Nicholas L, Carragher, Neil O, D'Arca, Domenico, Caporali, Andrea

    المساهمون: Martello, Andrea, Lauriola, Angela, Mellis, David, Parish, Elisa, Dawson, John C, Imrie, Lisa, Vidmar, Martina, Gammoh, Noor, Mitić, Tijana, Brittan, Mairi, Mills, Nicholas L, Carragher, Neil O, D'Arca, Domenico, Caporali, Andrea

    مصطلحات موضوعية: GABARAP, SQSTM1/p62, autophagy, centriolar satellites, endothelial cells

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32337819; info:eu-repo/semantics/altIdentifier/wos/WOS:000528587500001; volume:21; issue:7; firstpage:e48192; lastpage:1; numberofpages:16; journal:EMBO REPORTS; https://hdl.handle.net/11562/1116956Test

    الإتاحة: https://doi.org/10.15252/embr.201948192Test
    https://hdl.handle.net/11562/1116956Test

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  9. 9
    دورية أكاديمية
    Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells

    المؤلفون: Lauriola, Angela, Martello, Andrea, Fantini, Sebastian, Marverti, Gaetano, Zanocco-Marani, Tommaso, Davalli, Pierpaola, Guardavaccaro, Daniele, Mai, Sabine, Caporali, Andrea, D’Arca, Domenico

    المساهمون: Lauriola, Angela, Martello, Andrea, Fantini, Sebastian, Marverti, Gaetano, Zanocco-Marani, Tommaso, Davalli, Pierpaola, Guardavaccaro, Daniele, Mai, Sabine, Caporali, Andrea, D’Arca, Domenico

    مصطلحات موضوعية: mitostatin, cancer, spindle assembly checkpoint (SAC), Mad2, chromosome mis-segregation, chromosome instability (CIN), DNA damage, spectral karyotyping (SKY)

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32316593; info:eu-repo/semantics/altIdentifier/wos/WOS:000535587400221; volume:12; issue:4; firstpage:993; lastpage:1008; journal:CANCERS; http://hdl.handle.net/11380/1201284Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85083983571

    الإتاحة: https://doi.org/10.3390/cancers12040993Test
    http://hdl.handle.net/11380/1201284Test

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  10. 10
    دورية أكاديمية
    A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells

    المؤلفون: Marverti, Gaetano, Gozzi, Gaia, Maretti, Eleonora, Lauriola, Angela, Severi, Leda, Sacchetti, Francesca, Losi, Lorena, Pacifico, Salvatore, Ferrari, Stefania, Ponterini, Glauco, Leo, Eliana, Costi, Maria Paola, D'Arca, Domenico

    المساهمون: Marverti, Gaetano, Gozzi, Gaia, Maretti, Eleonora, Lauriola, Angela, Severi, Leda, Sacchetti, Francesca, Losi, Lorena, Pacifico, Salvatore, Ferrari, Stefania, Ponterini, Glauco, Leo, Eliana, Costi, Maria Paola, D'Arca, Domenico

    مصطلحات موضوعية: 5-fluorouracil, pH-sensitive PEGylated liposomes, human thymidylate synthase peptidic-inhibitors, ovarian cancer, drug-resistance

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32585842; info:eu-repo/semantics/altIdentifier/wos/WOS:000549372400001; volume:21; issue:12; firstpage:4452-1; lastpage:4452-21; numberofpages:21; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/11392/2503074Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85086912650; https://www.mdpi.com/1422-0067/21/12/4452Test

    الإتاحة: https://doi.org/10.3390/ijms21124452Test
    https://hdl.handle.net/11392/2503074Test
    https://www.mdpi.com/1422-0067/21/12/4452Test

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