المساهمون: Gang Wang, Jianlong Li, Linda Bojmar, Haiyan Chen, Zhong Li, Gabriel C Tobias, Mengying Hu, Edwin A Homan, Serena Lucotti, Fengbo Zhao, Valentina Posada, Peter R Oxley, Michele Cioffi, Han Sang Kim, Huajuan Wang, Pernille Lauritzen, Nancy Boudreau, Zhanjun Shi, Christin E Burd, Jonathan H Zippin, James C Lo, Geoffrey S Pitt, Jonathan Hernandez, Constantinos P Zambirinis, Michael A Hollingsworth, Paul M Grandgenett, Maneesh Jain, Surinder K Batra, Dominick J DiMaio, Jean L Grem, Kelsey A Klute, Tanya M Trippett, Mikala Egeblad, Doru Paul, Jacqueline Bromberg, David Kelsen, Vinagolu K Rajasekhar, John H Healey, Irina R Matei, William R Jarnagin, Robert E Schwartz, Haiying Zhang, David Lyden, Kim, Han Sang

مصطلحات موضوعية: Animals, Cytochrome P-450 Enzyme System / genetics, Extracellular Vesicles* / metabolism, Fatty Acids* / metabolism, Fatty Liver* / drug therapy, Fatty Liver* / etiology, Fatty Liver* / metabolism, Fatty Liver* / prevention & control, Humans, Inflammation / metabolism, Kupffer Cells, Liver Neoplasms / secondary, Liver* / metabolism, Liver* / pathology, Liver* / physiopathology, Mice, Oxidative Phosphorylation, Palmitic Acid / metabolism, Pancreatic Neoplasms* / metabolism, Pancreatic Neoplasms* / pathology, Tumor Microenvironment, Tumor Necrosis Factor-alpha / antagonists & inhibitors, Tumor Necrosis Factor-alpha / metabolism, rab27 GTP-Binding Proteins / deficiency

العلاقة: NATURE; J02289; OAK-2023-02363; https://ir.ymlib.yonsei.ac.kr/handle/22282913/195981Test; https://www.nature.com/articles/s41586-023-06114-4Test; T202304189; NATURE, Vol.618(7964) : 374-382, 2023-06

الإتاحة: https://doi.org/10.1038/s41586-023-06114-4Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/195981Test
https://www.nature.com/articles/s41586-023-06114-4Test

المؤلفون: Järvinen, Erkka, Hammer, Helen S., Pötz, Oliver, Ingelman-Sundberg, Magnus, Stage, Tore Bjerregaard

المصدر: Järvinen , E , Hammer , H S , Pötz , O , Ingelman-Sundberg , M & Stage , T B 2023 , ' 3D Spheroid Primary Human Hepatocytes for Prediction of Cytochrome P450 and Drug Transporter Induction ' , Clinical Pharmacology and Therapeutics , vol. 113 , no. 6 , pp. 1284-1294 . https://doi.org/10.1002/cpt.2887Test

مصطلحات موضوعية: Carrier Proteins/metabolism, Cells, Cultured, Cytochrome P-450 CYP2B6/metabolism, Cytochrome P-450 CYP2C19/metabolism, Cytochrome P-450 CYP2C8/metabolism, Cytochrome P-450 CYP2C9/metabolism, Cytochrome P-450 CYP2D6/metabolism, Cytochrome P-450 CYP3A/metabolism, Cytochrome P-450 Enzyme System/genetics, Hepatocytes/metabolism, Humans, Liver-Specific Organic Anion Transporter 1/metabolism, Membrane Transport Proteins/genetics, RNA, Messenger/metabolism, Rifampin/pharmacology

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/887166f0-37c3-41e6-9c33-8ea727418813Test

الإتاحة: https://doi.org/10.1002/cpt.2887Test
https://portal.findresearcher.sdu.dk/da/publications/887166f0-37c3-41e6-9c33-8ea727418813Test
https://findresearcher.sdu.dk/ws/files/240037563/Clin_Pharma_and_Therapeutics_2023_J_rvinen.pdfTest

المؤلفون: Järvinen, Erkka, Dalgård Dunvald, Ann Cathrine, Ernst, Martin Thomsen, Hammer, Helen S., Pötz, Oliver, Pottegård, Anton, Stage, Tore B.

المصدر: Järvinen , E , Dalgård Dunvald , A C , Ernst , M T , Hammer , H S , Pötz , O , Pottegård , A & Stage , T B 2023 , ' Dicloxacillin-warfarin drug–drug interaction—A register-based study and in vitro investigations in 3D spheroid primary human hepatocytes ' , British Journal of Clinical Pharmacology , vol. 89 , no. 8 , pp. 2614-2624 . https://doi.org/10.1111/bcp.15738Test

مصطلحات موضوعية: anticoagulant, CYP, drug–drug interactions, induction, INR monitoring, primary human hepatocytes, warfarin, Cytochrome P-450 Enzyme System/genetics, Humans, Anticoagulants/adverse effects, International Normalized Ratio, Warfarin/adverse effects, Drug Interactions, Hepatocytes, Dicloxacillin/pharmacology, Floxacillin/pharmacology

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/5e72e903-ac01-44d8-8ae6-50b7a53c6a68Test

الإتاحة: https://doi.org/10.1111/bcp.15738Test
https://portal.findresearcher.sdu.dk/da/publications/5e72e903-ac01-44d8-8ae6-50b7a53c6a68Test
https://findresearcher.sdu.dk/ws/files/254844265/Brit_J_Clinical_Pharma_-_2023_-_J_rvinen_-_Dicloxacillin_warfarin_drug_drug_interaction_A_register_based_study_and_in_vitro.pdfTest

المؤلفون: Achour, Brahim, Gosselin, Pauline, Terrier, Jean, Gloor, Yvonne, Al‐Majdoub, Zubida M., Polasek, Thomas M., Daali, Youssef, Rostami‐Hodjegan, Amin, Reny, Jean‐Luc

المصدر: Achour , B , Gosselin , P , Terrier , J , Gloor , Y , Al‐Majdoub , Z M , Polasek , T M , Daali , Y , Rostami‐Hodjegan , A & Reny , JL 2022 , ' Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P‐Glycoprotein Activities ' , Clinical Pharmacology & Therapeutics , vol. 111 , no. 6 , pp. 1268-1277 . https://doi.org/10.1002/cpt.2576Test

مصطلحات موضوعية: ATP Binding Cassette Transporter, Subfamily B, Biomarkers, Cardiovascular Diseases/diagnosis, Cytochrome P-450 CYP2C19/genetics, Cytochrome P-450 CYP2C9/genetics, Cytochrome P-450 CYP3A/metabolism, Cytochrome P-450 Enzyme System/genetics, Humans, Liquid Biopsy, Membrane Transport Proteins

الإتاحة: https://doi.org/10.1002/cpt.2576Test
https://research.manchester.ac.uk/en/publications/6f06ed70-6165-4a8d-83a0-d3032aeb5271Test

المؤلفون: Mo, Hai-Ying, Wei, Qi-Yao, Zhong, Qiu-Hua, Zhao, Xiao-Yun, Guo, Dan, Han, Jin, Noracharttiyapot, Wachiraporn, Visser, Lydia, van den Berg, Anke, Xu, Yan-Ming, Lau, Andy T Y

المصدر: Mo , H-Y , Wei , Q-Y , Zhong , Q-H , Zhao , X-Y , Guo , D , Han , J , Noracharttiyapot , W , Visser , L , van den Berg , A , Xu , Y-M & Lau , A T Y 2022 , ' Cytochrome P450 27C1 Level Dictates Lung Cancer Tumorigenicity and Sensitivity towards Multiple Anticancer Agents and Its Potential Interplay with the IGF-1R/Akt/p53 Signaling Pathway ' , International Journal of Molecular Sciences , vol. 23 , no. 14 , 7853 . https://doi.org/10.3390/ijms23147853Test

مصطلحات موضوعية: Antineoplastic Agents/pharmacology, Apoptosis, Cell Line, Tumor, Cell Proliferation, Cytochrome P-450 Enzyme System/genetics, Humans, Lung Neoplasms/drug therapy, Proto-Oncogene Proteins c-akt/metabolism, Receptor, IGF Type 1/genetics, Signal Transduction, Tumor Suppressor Protein p53/genetics

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/a6bface3-33fb-4b63-9d16-4fa6d8a49b26Test

الإتاحة: https://doi.org/10.3390/ijms23147853Test
https://hdl.handle.net/11370/a6bface3-33fb-4b63-9d16-4fa6d8a49b26Test
https://research.rug.nl/en/publications/a6bface3-33fb-4b63-9d16-4fa6d8a49b26Test
https://pure.rug.nl/ws/files/232281392/ijms_23_07853_v2_1_.pdfTest

المؤلفون: Dunvald, Ann Cathrine Dalgård, Järvinen, Erkka, Mortensen, Christina, Stage, Tore B.

المصدر: Dunvald , A C D , Järvinen , E , Mortensen , C & Stage , T B 2022 , ' Clinical and Molecular Perspectives on Inflammation-Mediated Regulation of Drug Metabolism and Transport ' , Clinical Pharmacology and Therapeutics , vol. 112 , no. 2 , pp. 277-290 . https://doi.org/10.1002/cpt.2432Test

مصطلحات موضوعية: Cytochrome P-450 CYP3A/metabolism, Cytochrome P-450 Enzyme System/genetics, Cytokines/metabolism, Humans, Inactivation, Metabolic, Inflammation

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/819d1073-8f87-4373-bf7e-40e2ce832699Test

الإتاحة: https://doi.org/10.1002/cpt.2432Test
https://portal.findresearcher.sdu.dk/da/publications/819d1073-8f87-4373-bf7e-40e2ce832699Test
https://findresearcher.sdu.dk/ws/files/194331577/cpt.2432.pdfTest

المؤلفون: Loerracher, Ann-Kathrin, Braunbeck, Thomas

المصدر: http://lobid.org/resources/99370671250806441Test#!, 95(7):2299-2334.

مصطلحات موضوعية: Xenobiotic metabolism, Zebrafish Proteins/genetics [MeSH], Biotransformation, Biotransformation [MeSH], Zebrafish, Review Article, Embryo, Nonmammalian/metabolism [MeSH], Ecotoxicology, Mammals/metabolism [MeSH], Animals [MeSH], Cytochrome P-450 Enzyme System/metabolism [MeSH], Cytochrome P-450 Enzyme System/genetics [MeSH], Zebrafish [MeSH], Toxicology, Cytochrome P450

العلاقة: https://repository.publisso.de/resource/frl:6451681Test; https://doi.org/10.1007/s00204-021-03071-7Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241672Test/

الإتاحة: https://doi.org/10.1007/s00204-021-03071-7Test
https://repository.publisso.de/resource/frl:6451681Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241672Test/

المؤلفون: Hochmuth, Luise, Körner, Christiane, Ott, Fritzi, Volke, Daniela, Blagotinšek Cokan, Kaja, Juvan, Peter, Brosch, Mario, Hofmann, Ute, Hoffmann, Ralf, Rozman, Damjana, Berg, Thomas, Matz-Soja, Madlen

المصدر: http://lobid.org/resources/99370671250806441Test#!, 95(9):3001-3013.

مصطلحات موضوعية: Transcriptome/physiology [MeSH], Drug metabolism, Mice, Inbred C57BL [MeSH], Melatonin/metabolism [MeSH], Liver, Male [MeSH], Signal Transduction/physiology [MeSH], Toxicokinetics and Metabolism, Aryl Hydrocarbon Hydroxylases/genetics [MeSH], Sex Characteristics [MeSH], Sex Factors [MeSH], Female [MeSH], Serotonin/metabolism [MeSH], Sexual dimorphism, Animals [MeSH], Hepatocytes/metabolism [MeSH], Hepatocytes, Cytochrome P-450 Enzyme System/genetics [MeSH], Cytochrome P450 Family 2/genetics [MeSH], Steroid Hydroxylases/genetics [MeSH], Lipid metabolism, Mice [MeSH], Proteome/physiology [MeSH], Cytochrome P450, Metabolome/physiology [MeSH], Gene Expression Regulation/physiology [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6451653Test; https://doi.org/10.1007/s00204-021-03118-9Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380230Test/

الإتاحة: https://doi.org/10.1007/s00204-021-03118-9Test
https://repository.publisso.de/resource/frl:6451653Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380230Test/

المؤلفون: Muchlinski, Andrew, Jia, Meirong, Tiedge, Kira, Fell, Jason S, Pelot, Kyle A, Chew, Lisl, Davisson, Danielle, Chen, Yuxuan, Siegel, Justin, Lovell, John T, Zerbe, Philipp

المصدر: Muchlinski , A , Jia , M , Tiedge , K , Fell , J S , Pelot , K A , Chew , L , Davisson , D , Chen , Y , Siegel , J , Lovell , J T & Zerbe , P 2021 , ' Cytochrome P450-catalyzed biosynthesis of furanoditerpenoids in the bioenergy crop switchgrass (Panicum virgatum L.) ' , Plant Journal , vol. 108 , no. 4 , pp. 1053-1068 . https://doi.org/10.1111/tpj.15492Test ; ISSN:0960-7412

مصطلحات موضوعية: Biocatalysis, Biological Products/chemistry, Biosynthetic Pathways, Catalytic Domain, Cytochrome P-450 Enzyme System/genetics, Diterpenes/chemistry, Genome, Plant/genetics, Panicum/chemistry, Plant Proteins/genetics, Plant Roots/chemistry

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1111/tpj.15492Test
http://hdl.handle.net/11370/4b4291f2-3643-4514-a0c6-87140a1154feTest
https://research.rug.nl/en/publicationsTest/cytochrome-p450catalyzed-biosynthesis-of-furanoditerpenoids-in-the-bioenergy-crop-switchgrass-panicum-virgatum-l(4b4291f2-3643-4514-a0c6-87140a1154fe).html
https://pure.rug.nl/ws/files/202643994/The_Plant_Journal_2021_Muchlinski_Cytochrome_P450_E2_80_90catalyzed_biosynthesis_of_furanoditerpenoids_in_the_bioenergy_crop.pdfTest

المؤلفون: Lenoir, Camille, Terrier, Jean, Gloor, Yvonne Sylvia, Curtin, François, Rollason, Victoria, Desmeules, Jules Alexandre, Daali, Youssef, Reny, Jean-Luc, Samer, Caroline Flora

المصدر: ISSN: 0009-9236 ; Clinical pharmacology and therapeutics, vol. 110, no. 5 (2021) p. 1358-1367.

مصطلحات موضوعية: info:eu-repo/classification/ddc/615, info:eu-repo/classification/ddc/616, info:eu-repo/classification/ddc/617, Aged, 80 and over, C-Reactive Protein / metabolism, COVID-19 / blood, COVID-19 / enzymology, Cytochrome P-450 Enzyme System / genetics, Cytochrome P-450 Enzyme System / metabolism, Female, Genetic Variation, Humans, Interleukin-6 / blood, Linear Models, Male, Middle Aged, Models, Theoretical, Prospective Studies, Tumor Necrosis Factor-alpha / blood

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34473836; https://archive-ouverte.unige.ch/unige:161947Test; unige:161947

الإتاحة: https://doi.org/10.1002/cpt.2412Test
https://archive-ouverte.unige.ch/unige:161947Test