المؤلفون: Alves, Carla L., Ehmsen, Sidse, Terp, Mikkel G., Portman, Neil, Tuttolomondo, Martina, Gammelgaard, Odd L., Hundebøl, Monique F., Kaminska, Kamila, Johansen, Lene E., Bak, Martin, Honeth, Gabriella, Bosch, Ana, Lim, Elgene, Ditzel, Henrik J.

المصدر: Alves , C L , Ehmsen , S , Terp , M G , Portman , N , Tuttolomondo , M , Gammelgaard , O L , Hundebøl , M F , Kaminska , K , Johansen , L E , Bak , M , Honeth , G , Bosch , A , Lim , E & Ditzel , H J 2021 , ' Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer ' , Nature Communications , vol. 12 , 5112 . https://doi.org/10.1038/s41467-021-25422-9Test

مصطلحات موضوعية: Breast Neoplasms/drug therapy, Cell Line, Tumor, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Cyclin-Dependent Kinase 6/antagonists & inhibitors, Disease Progression, Drug Resistance, Neoplasm, Drug Therapy, Combination, Female, Fulvestrant/administration & dosage, Humans, Molecular Targeted Therapy, Protein Kinase Inhibitors/administration & dosage, Proto-Oncogene Proteins c-akt/genetics

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/16ebb9be-b3ba-4857-9d6b-45c685175b25Test

الإتاحة: https://doi.org/10.1038/s41467-021-25422-9Test
https://portal.findresearcher.sdu.dk/da/publications/16ebb9be-b3ba-4857-9d6b-45c685175b25Test

المؤلفون: Martínez-Chávez, Alejandra, Rosing, Hilde, Hillebrand, Michel, Tibben, Matthijs, Schinkel, Alfred H, Beijnen, Jos H

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

مصطلحات موضوعية: Aminopyridines/analysis, Animals, Benzimidazoles/analysis, Chromatography, Liquid/methods, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Cyclin-Dependent Kinase 6/antagonists & inhibitors, Humans, Mice, Piperazines/analysis, Protein Kinase Inhibitors/analysis, Purines/analysis, Pyridines/analysis, Tandem Mass Spectrometry/methods

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/389668Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/389668Test

المساهمون: College of Medicine, Dept. of Pathology, H S Kim, M Jung, H N Kang, H Kim, C-W Park, S-M Kim, S J Shin, S H Kim, S G Kim, E K Kim, M R Yun, Z Zheng, K Y Chung, J Greenbowe, S M Ali, T-M Kim, Kim, Eun Kyung, Kim, Han Sang, Shin, Sang Joon, Chung, Kee Yang, Jung, Min Kyu, Cho, Byoung Chul

مصطلحات موضوعية: Animals, Antineoplastic Agents/pharmacology, Apoptosis/drug effects, Biomarkers, Tumor/genetics, Tumor/metabolism, Cell Proliferation/drug effects, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Cyclin-Dependent Kinase 4/genetics, Cyclin-Dependent Kinase 4/metabolism, Cyclin-Dependent Kinase 6/antagonists & inhibitors, Cyclin-Dependent Kinase 6/genetics, Cyclin-Dependent Kinase 6/metabolism, Female, Humans, MAP Kinase Kinase 1/antagonists & inhibitors, MAP Kinase Kinase 1/genetics, MAP Kinase Kinase 1/metabolism, Melanoma/drug therapy, Melanoma/metabolism, Melanoma/pathology, Mice, Nude, Mitogen-Activated Protein Kinases/metabolism, Mucous Membrane/drug effects, Mucous Membrane/metabolism, Mucous Membrane/pathology, Oncogene Proteins, Fusion/genetics, Fusion/metabolism

العلاقة: ONCOGENE; J02413; OAK-2017-05061; https://ir.ymlib.yonsei.ac.kr/handle/22282913/160849Test; http://www.nature.com/articles/onc2016486Test; T201703491; ONCOGENE, Vol.36(23) : 3334-3345, 2017

الإتاحة: https://doi.org/10.1038/onc.2016.486Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160849Test
http://www.nature.com/articles/onc2016486Test

المؤلفون: Jerby-Arnon, L., Neftel, C., Shore, M.E., Weisman, H.R., Mathewson, N.D., McBride, M.J., Haas, B., Izar, B., Volorio, A., Boulay, G., Cironi, L., Richman, A.R., Broye, L.C., Gurski, J.M., Luo, C.C., Mylvaganam, R., Nguyen, L., Mei, S., Melms, J.C., Georgescu, C., Cohen, O., Buendia-Buendia, J.E., Segerstolpe, A., Sud, M., Cuoco, M.S., Labes, D., Gritsch, S., Zollinger, D.R., Ortogero, N., Beechem, J.M., Petur Nielsen, G., Chebib, I., Nguyen-Ngoc, T., Montemurro, M., Cote, G.M., Choy, E., Letovanec, I., Cherix, S., Wagle, N., Sorger, P.K., Haynes, A.B., Mullen, J.T., Stamenkovic, I., Rivera, M.N., Kadoch, C., Wucherpfennig, K.W., Rozenblatt-Rosen, O., Suvà, M.L., Riggi, N., Regev, A.

المصدر: Nature medicine, vol. 27, no. 2, pp. 289-300

مصطلحات موضوعية: Carcinogenesis/genetics, Cell Line, Tumor, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Histone Deacetylase Inhibitors/therapeutic use, Histone Deacetylases/genetics, Histone Deacetylases/therapeutic use, Humans, Molecular Targeted Therapy, Oncogene Proteins, Fusion/antagonists & inhibitors, Fusion/genetics, Oncogenes/genetics, RNA-Seq, Sarcoma, Synovial/drug therapy, Synovial/genetics, Synovial/pathology, Single-Cell Analysis

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33495604; info:eu-repo/semantics/altIdentifier/eissn/1546-170X; https://serval.unil.ch/notice/serval:BIB_39EC1C431B02Test; urn:issn:1078-8956

الإتاحة: https://doi.org/10.1038/s41591-020-01212-6Test
https://serval.unil.ch/notice/serval:BIB_39EC1C431B02Test

المؤلفون: Oricchio, E., Ciriello, G., Jiang, M., Boice, M.H., Schatz, J.H., Heguy, A., Viale, A., de Stanchina, E., Teruya-Feldstein, J., Bouska, A., McKeithan, T., Sander, C., Tam, W., Seshan, V.E., Chan, W.C., Chaganti, R.S., Wendel, H.G.

المصدر: The Journal of experimental medicine, vol. 211, no. 7, pp. 1379-1391

مصطلحات موضوعية: Animals, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Cell Line, Tumor, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Cyclin-Dependent Kinase 4/genetics, Cyclin-Dependent Kinase 4/metabolism, Cyclin-Dependent Kinase Inhibitor p15/genetics, Cyclin-Dependent Kinase Inhibitor p15/metabolism, Cyclin-Dependent Kinase Inhibitor p16/genetics, Cyclin-Dependent Kinase Inhibitor p16/metabolism, Humans, Lymphoma, Follicular/drug therapy, Follicular/genetics, Follicular/metabolism, Follicular/pathology, Male, Mice, Neoplasms, Experimental/drug therapy, Experimental/genetics, Experimental/metabolism, Experimental/pathology, Proto-Oncogene Proteins c-bcl-2/genetics, Proto-Oncogene Proteins c-bcl-2/metabolism, Retinoblastoma Protein/genetics, Retinoblastoma Protein/metabolism

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/24913233; info:eu-repo/semantics/altIdentifier/eissn/1540-9538; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_48D4D91B51197; https://serval.unil.ch/notice/serval:BIB_48D4D91B5119Test; urn:issn:0022-1007; https://serval.unil.ch/resource/serval:BIB_48D4D91B5119.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_48D4D91B51197Test

الإتاحة: https://doi.org/10.1084/jem.20132120Test
https://serval.unil.ch/notice/serval:BIB_48D4D91B5119Test
https://serval.unil.ch/resource/serval:BIB_48D4D91B5119.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_48D4D91B51197Test

المؤلفون: Ana Bosch, Mikkel G. Terp, Henrik J. Ditzel, Monique F. Hundebøl, Neil Portman, Lene E. Johansen, Kamila Kaminska, Gabriella Honeth, Carla Maria Lourenco Alves, Martin Bak, Odd L. Gammelgaard, Elgene Lim, Martina Tuttolomondo, Sidse Ehmsen

المصدر: Nature Communications
Alves, C L, Ehmsen, S, Terp, M G, Portman, N, Tuttolomondo, M, Gammelgaard, O L, Hundebøl, M F, Kaminska, K, Johansen, L E, Bak, M, Honeth, G, Bosch, A, Lim, E & Ditzel, H J 2021, ' Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer ', Nature Communications, vol. 12, 5112 . https://doi.org/10.1038/s41467-021-25422-9Test
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Fulvestrant/administration & dosage, endocrine system diseases, medicine.drug_class, Science, General Physics and Astronomy, Breast Neoplasms, Proto-Oncogene Proteins c-akt/genetics, Article, General Biochemistry, Genetics and Molecular Biology, Metastasis, Breast cancer, Breast Neoplasms/drug therapy, Cell Line, Tumor, Medicine, Humans, Molecular Targeted Therapy, neoplasms, Protein kinase B, Fulvestrant, Protein Kinase Inhibitors, Multidisciplinary, integumentary system, business.industry, Protein Kinase Inhibitors/administration & dosage, Endocrine therapy, Cancer, Cyclin-Dependent Kinase 4, General Chemistry, Cyclin-Dependent Kinase 6, Cyclin-Dependent Kinase 6/antagonists & inhibitors, Translational research, medicine.disease, Publisher Correction, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Estrogen, Tumor progression, Drug Resistance, Neoplasm, Cancer research, Disease Progression, Drug Therapy, Combination, Female, biological phenomena, cell phenomena, and immunity, business, Proto-Oncogene Proteins c-akt, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909c54d06c561d241308a49e7f7f6e84Test
https://pubmed.ncbi.nlm.nih.gov/34531405Test

المساهمون: H.-S. Kim, W. J. Lee, S. W. Lee, H.-W. Chae, D. H. Kim, Y. Oh, Lee, Sun Woo, Chae, Hyun Wook, Kim, Duk Hee, Kim, Ho Seong

مصطلحات موضوعية: Breast Neoplasms/enzymology, Breast Neoplasms/genetics, Breast Neoplasms/pathology, Cell Line, Tumor, Cell Proliferation/drug effects, Cyclin D1/genetics, Cyclin D1/metabolism, Cyclin-Dependent Kinase 2/antagonists & inhibitors, Cyclin-Dependent Kinase 2/metabolism, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Cyclin-Dependent Kinase 4/metabolism, Cyclin-Dependent Kinase Inhibitor Proteins/metabolism, Ecdysterone/analogs & derivatives, Ecdysterone/pharmacology, Female, G1 Phase*/drug effects, Gene Expression Regulation, Neoplastic/drug effects, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor Binding Proteins/metabolism, RNA, Messenger/genetics, Messenger/metabolism

وصف الملف: 165~172

العلاقة: HORMONE AND METABOLIC RESEARCH; J00999; OAK-2010-00844; https://ir.ymlib.yonsei.ac.kr/handle/22282913/101244Test; T201001884; HORMONE AND METABOLIC RESEARCH, Vol.42(3) : 165-172, 2010

الإتاحة: https://doi.org/10.1055/s-0029-1243190Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101244Test

المؤلفون: Martínez-Carreres, L., Puyal, J., Leal-Esteban, L.C., Orpinell, M., Castillo-Armengol, J., Giralt, A., Dergai, O., Moret, C., Barquissau, V., Nasrallah, A., Pabois, A., Zhang, L., Romero, P., Lopez-Mejia, I.C., Fajas, L.

المصدر: Cancer research, vol. 79, no. 20, pp. 5245-5259

مصطلحات موضوعية: Adenylate Kinase/metabolism, Aminopyridines/pharmacology, Aminopyridines/therapeutic use, Animals, Autophagosomes/physiology, Autophagy/physiology, Benzimidazoles/pharmacology, Benzimidazoles/therapeutic use, Cell Line, Tumor, Cellular Senescence/physiology, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Cyclin-Dependent Kinase 4/genetics, Cyclin-Dependent Kinase 4/physiology, Drug Synergism, Female, Gene Knockout Techniques, Humans, Insulin/physiology, Lysosomes/physiology, Lysosomes/ultrastructure, Mechanistic Target of Rapamycin Complex 1/metabolism, Mice, Inbred NOD, Molecular Targeted Therapy, Neoplasm Proteins/physiology, Phosphorylation, Protein Kinase Inhibitors/pharmacology, Protein Kinase Inhibitors/therapeutic use, Protein Processing

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31395606; info:eu-repo/semantics/altIdentifier/eissn/1538-7445; info:eu-repo/grantAgreement/SNF//310030_182332///; info:eu-repo/grantAgreement/SNF//310030-163064///; info:eu-repo/grantAgreement/SNF//31003A-159586///; info:eu-repo/grantAgreement/SNF//PZ00P3_168077///; https://serval.unil.ch/notice/serval:BIB_A55F9416C381Test; urn:issn:0008-5472; https://serval.unil.ch/resource/serval:BIB_A55F9416C381.P001/REF.pdfTest

الإتاحة: https://doi.org/10.1158/0008-5472.CAN-19-0708Test
https://serval.unil.ch/notice/serval:BIB_A55F9416C381Test
https://serval.unil.ch/resource/serval:BIB_A55F9416C381.P001/REF.pdfTest