المؤلفون: Ya Wang, Shuailin Hao, Hailong Wang, Jianping Ren, Shuyuan Zhang, Yuqin Zhao, Yan Wu, Xingzhi Xu, Lixiu Lin, Youhang Li

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, CtIP, C-terminal–binding protein–interacting protein, BiFC, bimolecular fluorescence complementation, EMSA, electrophoretic mobility shift assay, MRN, MRE11–RAD50–NBS1, Biochemistry, Metastasis, U2OS, human osteosarcoma cell line, Mice, microRNA maturation, RAD50, ATP-binding cassette—ATPase, Neoplasm Metastasis, Rhed, RNA-binding heme domain, EGFP, enhanced GFP, biology, NBS1, Nijmegen breakage syndrome protein 1, ChIP, chromatin immunoprecipitation, Cell Transformation, Neoplastic, Colonic Neoplasms, microprocessor, DDX5, DEAD-box helicase 5, RNase, ribonuclease, Research Article, PIC, protease inhibitor cocktail, DGCR8, DNA repair, VN, Venus N-terminal fragment, CtBP, C-terminal–binding protein, Proto-Oncogene Proteins pp60(c-src), pri-miRNA, miRNA primary transcripts, DGCR8, DiGeorge syndrome critical region gene 8, Drosha, 03 medical and health sciences, cDNA, complementary DNA, MRE11, meiotic recombination 11, RPA, replication protein A, Cell Line, Tumor, microRNA, GST, glutathione-S-transferase, medicine, metastasis, Animals, Humans, DSB, double-strand break, Molecular Biology, NETN, NaCl, EDTA, Tris–HCl, and NP-40 buffer, Endodeoxyribonucleases, 030102 biochemistry & molecular biology, PLA, proximity ligation assay, Cell Biology, medicine.disease, VC, Venus C-terminal fragment, MicroRNAs, 030104 developmental biology, BRCA1, breast cancer 1, CtIP, Tumor progression, Rad50, Cancer cell, Cancer research, biology.protein, HR, homologous recombination, pre-miRNAs, precursor miRNAs, qPCR, quantitative PCR

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938d7583732d45a2cf082d842bb7cc54Test
http://europepmc.org/articles/PMC8164041Test

المؤلفون: William E. Royer, Celia A. Schiffer, Jeffry C. Nichols

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Dehydrogenase, Transcription coregulator, Biochemistry, DNA-binding protein, MALS, 03 medical and health sciences, Tetramer, tetrameric assembly, TCEP, tris(2-carboxyethyl) phosphine, CtBP, C-terminal binding protein, medicine, Humans, structural biology, Nucleotide, CtBP, crystallography, Molecular Biology, chemistry.chemical_classification, 030102 biochemistry & molecular biology, Chemistry, NAD(H), MALS, multiangle light scattering, D2-HDH, D-isomer-specific 2-hydroxyacid dehydrogenase, Cell Biology, NAD, Adenosine, DNA-Binding Proteins, Alcohol Oxidoreductases, transcription coregulator, SEC, size-exclusion column, 030104 developmental biology, Structural biology, dehydrogenase, Biophysics, cancer target, NAD+ kinase, Protein Multimerization, Co-Repressor Proteins, NADP, Research Article, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae63f49298568958adbc7bb03781a10Test
https://doi.org/10.1016/j.jbc.2021.100351Test

المؤلفون: Marius C. Jones, Meritxell Rosell, Malcolm G. Parker

المصدر: Biochimica et Biophysica Acta

مصطلحات موضوعية: HFD, high-fat diet, RBP4, retinol binding protein 4, Peroxisome proliferator-activated receptor, Adipose tissue, HDAC, histone deacetylase, Review, White adipose tissue, 0302 clinical medicine, CtBP, C-terminal binding protein, FOXC2, forkhead-box C2, SMRT, silencing mediator of retinoic acid and thyroid hormone receptor, Metabolic Syndrome, chemistry.chemical_classification, PRDM16, CREB, CRE-binding protein, PGC, PPARγ coactivator, PRDM16, positive regulatory domain-containing 16, 0303 health sciences, EDL, extensor digitorum longus, Muscles, Nuclear Proteins, SRC, steroid receptor coactivator, NR, nuclear receptor, FAS, fatty acid synthase, NRF, nuclear respiratory factor, Nuclear Receptor Interacting Protein 1, 3. Good health, Adipose Tissue, Dnmt, DNA methyltransferase, TNFα, tumour necrosis factor α, 030220 oncology & carcinogenesis, Molecular Medicine, ERR, estrogen related receptor, NF-κB, nuclear factor κB, CPT, 1β carnitine palmitoyltransferase 1β, ATF, activating transcription factors, CBP, CRE-binding protein, TR, thyroid hormone receptor, TLR, Toll-like receptor, medicine.medical_specialty, RXR, retinoid X receptor, CIDEA, cell death-inducing DNA fragmentation factor alpha-like effector A, JNK, Janus N-terminal kinase, Biology, TAG, triacylglyceride, 03 medical and health sciences, MEF, myocyte-specific enhancer binding factor, ROS, reactive oxygen species, VLDL, very low density lipoprotein, Internal medicine, UCP1, uncoupling protein 1, medicine, Animals, Humans, SREBP1c, sterol regulatory element binding protein 1c, Molecular Biology, Adaptor Proteins, Signal Transducing, 030304 developmental biology, Inflammation, GLUT4, glucose transporter 4, GR, glucocorticoid receptor, FA, fatty acid, PPAR, peroxixome proliferator-activated receptor, medicine.disease, Obesity, IL, interleukin, Endocrinology, RIP140, chemistry, Nuclear receptor, RAR, retinoic acid receptor, biology.protein, PEPCK, phosphoenolpyruvate carboxykinase, AR, androgen receptor, NCoR, nuclear receptor corepressor, Steatosis, Metabolic syndrome, PCOS, polycystic ovary syndrome, GLUT4

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d2e6881e36fe40574534f7da45cc15Test

المؤلفون: Anna, Baghdasaryan, Peter, Chiba, Michael, Trauner

المصدر: Molecular Aspects of Medicine

مصطلحات موضوعية: PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1 alpha, FXR, farnesoid X receptor (NR1H4), HNF4α, hepatocyte nuclear factor 4 alpha, CARM1, co-activator-associated arginine methyltransferase 1, OATP, organic anion transporting polypeptide, VDR (NR1I1), vitamin D receptor, Review, BCRP (ABCG2), breast cancer resistance protein, NDRG2, NMYC downstrean-regulated gene 2, MRP4 (ABCC4), multidrug resistance-associated protein 4, SRC2, steroid receptor co-activator 2, GGT, gamma-glutamyl transpeptidase, MDR1 (ABCB1), multidrug resistance protein 1, Nuclear receptors, GRE, glucocorticoid response element, CtBP, C-terminal binding protein, GCA, glycocholic acid, TβMCA, β-tauromuricholic acid, TNF-α, tumor necrosis factor alpha, ATB-binding cassette transporters, FGF19/FGF15, fibroblast growth factor 19/15, MARE, MAF recognition element, ATP Binding Cassette Transporter, Subfamily B, Member 11, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, Cholestasis, ASBT (SLC10A2), apical sodium-dependent bile acid transporter, Symporters, AE2 (SLC4A2), anion exchanger 2, ABC, ATP-binding cassette, FXRE, FXR response element, cAMP, cyclic adenosine monophosphate, DILI, drug-induced liver injury, IL-6, interleukin 6, PL, phospholipid, TGR5, G protein coupled bile acid receptor, OCA, obeticholic acid, OSTα/OSTβ (SLC51A/SLC51B), organic solute transporter alpha/beta, LRH1 (NR5A2), liver receptor homologue 1, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, LPS, lipopolysaccharide, BRIC2, benign recurrent intrahepatic cholestasis type 2, LXR (NR1H3), liver X receptor, Transcriptional Activation, PFIC2, progressive familial intrahepatic cholestasis type 2, PXR (NR1I2), pregnane X receptor, TCA, taurocholic acid, RXRα (NR2B1), retinoid X receptor, Organic Anion Transporters, Sodium-Dependent, CCl4, carbone tetrachloride, UDCA, ursodeoxycholic acid, Bile Acids and Salts, CDCA, chenodeoxycholic acid, STAT-5, signal transducer and activator of transcription 5, LCA, litocholic acid, ALT, alanine aminotransferase, CBDL, common bile duct ligation, IR-1, inverse repeat 1, TUDCA, tauroursodeoxycholic acid, Humans, ICP, intrahepatic cholestasis of pregnancy, GR (NR3C1), glucocorticoid receptor, MRP2 (ABCC2), multidrug resistance-associated protein 2, TαMCA, α-tauromuricholic acid, TPN, total parenteral nutrition, ALP, alkaline phosphatase, IL-1β, interleukin-1 beta, SREBP1, sterol regulatory element-binding protein 1, Membrane Transport Proteins, Biological Transport, BSEP (ABCB11), bile salt export pump, MAF, musculo-aponeurotic fibrosacroma, ASCOM, activating signal cointegrator-2-containing complex, HNF1α, hepatocyte nuclear factor 1 alpha, MCL-1, myeloid cell leukemia factor 1, NTCP (SLC10A1), Na+-taurocholate cotransporting polypeptide solute carrier family 10 member 1, VPAC-1, vasoactive intestinal polypeptide activated receptor, AMPK, AMP-activated protein kinase, MRP3 (ABCC3), multidrug resistance-associated protein 3, NF-κB, nuclear factor kappa-B, PSC, primary sclerosing cholangitis, Gene Expression Regulation, DCA, deoxycholic acid, BS, bile salt, MDR2 (ABCB4), multidrug resistance protein 2, PPARα (NR1C1), peroxisome proliferator-activated receptor alpha, SHP (NR0B2), short heterodimer partner, RARα (NR1B1), retinoic acid receptor, ATP-Binding Cassette Transporters, PBC, primary biliary cirrhosis, PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::02c2316b6e5fe1c1e107f32e273f6aebTest
https://pubmed.ncbi.nlm.nih.gov/24333169Test

المؤلفون: Kinyui Alice Lo, Lei Sun

المصدر: Bioscience Reports
Bioscience Reports, Vol 33, Iss 5, p e00065 (2013)

مصطلحات موضوعية: Adipocytes, White, PGI2, prostacyclin, lcsh:Life, lcsh:QR1-502, Adipose tissue, FGF21, fibroblast growth factor 21, White adipose tissue, Review Article, Biochemistry, TIF2, transcriptional intermediary factor-2, lcsh:Microbiology, peroxisome-proliferator-activated receptor γ coactivator 1-α (PGC-1α), C/EBP, CCAAT/enhancer-binding protein, Adipose Tissue, Brown, Lipid droplet, Brown adipose tissue, miRNA, microRNA, SVF, stromal vascular fraction, TBX15, T-box 15, Elovl3, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3, PRDM16, PKA, protein kinase A (=cAMP-dependent protein kinase), TFAM, mitochondrial transcription factor A, WAT, white adipose tissue, eIF4E, eukaryotic translation initiation factor 4E, TRPV4, transient receptor potential vanilloid 4, Thermogenin, medicine.anatomical_structure, FoxC2, forkhead box protein C2, EBF2, early B cell factor-2, beige fat, ATF2, activating transcription factor 2, PRDM16, PR domain containing 16, medicine.medical_specialty, white adipocytes, Adipose tissue macrophages, Adipose Tissue, White, Biophysics, Biology, PGC-1α, peroxisome-proliferator-activated receptor γ coactivator 1α, Internal medicine, Coactivator, UCP1, uncoupling protein 1, medicine, Animals, Humans, PR domain containing 16 (PRDM16), CtBP, C-terminal-binding protein, SRC-1, steroid receptor coactivator-1, ANP, atrial natriuretic peptide, Cidea, cell death-inducing DFFA-like effector a, Molecular Biology, peroxisome-proliferator-activated receptor γ (PPARγ), browning, Myf5, myogenic factor 5, 4E-BP1, eukaryotic translation initiation factor 4E binding protein 1, pRb, retinoblastoma protein, NPRC, natriuretic peptide receptor C, PPARγ, peroxisome-proliferator-activated receptor gamma, BMP7, bone morphogenetic protein 7, Cell Biology, Lipid Metabolism, CNP, cardiac natriuretic peptide, Hormones, BAT, brown adipose tissue, lcsh:QH501-531, Endocrinology, PKG, protein kinase G (=cGMP-dependent protein kinase), Gene Expression Regulation, COX2, cyclo-oxygenase 2, Cell Transdifferentiation, MAPK, mitogen-activated protein kinase, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cf6225e6dbb0db42e19e9637ad71e7Test
https://pubmed.ncbi.nlm.nih.gov/23895241Test

المؤلفون: Nicholas P. Robinson, Sian Bray, Joseph D. Maman, John K. Blackwood, Luca Pellegrini, Neil J. Rzechorzek

المصدر: Biochemical Society Transactions

مصطلحات موضوعية: DNA, Bacterial, S1, DNA repair, Biology, Biochemistry, 03 medical and health sciences, RPA, replication protein A, SMC, structural maintenance of chromosomes, Chi, crossover hotspot initiator, DSB, double-strand break, Strand invasion, Replication protein A, Phylogeny, 030304 developmental biology, CDK, cyclin-dependent kinase, Genetics, chemistry.chemical_classification, Independent Meeting, 0303 health sciences, DNA ligase, DNA clamp, Circular bacterial chromosome, 030302 biochemistry & molecular biology, DNA, NHEJ, non-homologous end-joining, Sbc, suppressors of RecBC, DNA, Archaeal, Eukaryotic Cells, BLM, Bloom’s syndrome protein, chemistry, CtIP, CtBP (C-terminal-binding protein)-interacting protein, HR, homologous recombination, Homologous recombination, In vitro recombination, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301f263d7efbef0ec94616994ff2f401Test
https://pubmed.ncbi.nlm.nih.gov/23356304Test