المؤلفون: Carty, Michael, Kearney, Jay, Shanahan, Katharine A., Hams, Emily, Sugisawa, Ryoichi, Connolly, Dympna, Doran, Ciara G., Muñoz-Wolf, Natalia, Gürtler, Claudia, Fitzgerald, Katherine A., Lavelle, Ed C., Fallon, Padraic G., Bowie, Andrew G.

المساهمون: Science Foundation Ireland, Biotechnology and Biological Sciences Research Council-Science Foundation Ireland

المصدر: Immunity ; volume 50, issue 6, page 1412-1424.e6 ; ISSN 1074-7613

الإتاحة: https://doi.org/10.1016/j.immuni.2019.04.005Test
https://api.elsevier.com/content/article/PII:S1074761319301852?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1074761319301852?httpAccept=text/plainTest

المؤلفون: Dunphy, Gillian, Flannery, Sinéad M, Almine, Jessica F, Connolly, Dympna J, Paulus, Christina, Jonsson, Kasper L, Jakobsen, Martin R, Nevels, Michael Martin, Bowie, Andrew G, Unterholzner, Leonie

المصدر: Dunphy , G , Flannery , S M , Almine , J F , Connolly , D J , Paulus , C , Jonsson , K L , Jakobsen , M R , Nevels , M M , Bowie , A G & Unterholzner , L 2018 , ' Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-κB signalling after nuclear DNA damage ' , Molecular Cell , vol. 71 , no. 5 , e5 , pp. 745-760 . https://doi.org/10.1016/j.molcel.2018.07.034Test

مصطلحات موضوعية: Innate immunity, DNA damage, Etoposide, Interferon, IFI16, STING, p53, TRAF6, Ubiquitin

وصف الملف: application/pdf

العلاقة: https://research-portal.st-andrews.ac.uk/en/researchoutput/noncanonical-activation-of-the-dna-sensing-adaptor-sting-by-atm-and-ifi16-mediates-nfb-signalling-after-nuclear-dna-damageTest(e92f7d2b-b839-4c92-b0bd-4fbd2d175b5b).html

الإتاحة: https://doi.org/10.1016/j.molcel.2018.07.034Test
https://research-portal.st-andrews.ac.uk/en/researchoutput/noncanonical-activation-of-the-dna-sensing-adaptor-sting-by-atm-and-ifi16-mediates-nfb-signalling-after-nuclear-dna-damageTest(e92f7d2b-b839-4c92-b0bd-4fbd2d175b5b).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/16034/1/Dunphy_2018_MC_non_canonical_CC.pdfTest
https://www.sciencedirect.com/science/article/pii/S1097276518306038?dgcid=raven_sd_search_email#app2Test

المؤلفون: Bowie, Andrew, Dunphy, Gillian, Flannery, Sin?ad M., Almine, Jessica F., Connolly, Dympna J., Paulus, Christina, J?nsson, Kasper L., Jakobsen, Martin R., Nevels, Michael M., Unterholzner, Leonie

مصطلحات موضوعية: Detection of etoposide-induced damage by ATM, Innate immunity, DNA damage, Etoposide, Interferon, IFI16, STING, p53, TRAF6, Ubiquitin

وصف الملف: 745-760.e5

العلاقة: Molecular cell; 71; 5; Dunphy, G., Flannery, S.M., Almine, J.F., Connolly, D.J., Paulus, C., J?nsson, K.L., Jakobsen, M.R., Nevels, M.M., Bowie, A.G. & Unterholzner, L., Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-?B Signaling after Nuclear DNA Damage., 2018, Molecular cell, 71, 5; Y; https://www.sciencedirect.com/science/article/pii/S1097276518306038?via%3DihubTest; http://hdl.handle.net/2262/91328Test; http://people.tcd.ie/agbowieTest; 196288; http://dx.doi.org/10.1016/j.molcel.2018.07.034Test; orcid:0000-0001-5316-4373

الإتاحة: https://doi.org/10.1016/j.molcel.2018.07.034Test
http://hdl.handle.net/2262/91328Test
https://www.sciencedirect.com/science/article/pii/S1097276518306038?via%3DihubTest
http://people.tcd.ie/agbowieTest

المؤلفون: Sisquella, Xavier, Ofir-Birin, Yifat, Pimentel, Matthew A, Cheng, Lesley, Abou Karam, Paula, Sampaio, Natalia G, Penington, Jocelyn Sietsma, Connolly, Dympna, Giladi, Tal, Scicluna, Benjamin J, Sharples, Robyn A, Waltmann, Andreea, Avni, Dror, Schwartz, Eli, Schofield, Louis, Porat, Ziv, Hansen, Diana S, Papenfuss, Anthony T, Eriksson, Emily M, Gerlic, Motti, Hill, Andrew F, Bowie, Andrew G, Regev-Rudzki, Neta

مصطلحات موضوعية: 3207 Medical microbiology, Chancellery, DNA sensors, malaria, Plasmodium falciparum, DNA, malaria parasites, pathogens, pattern recognition receptors, PRR

وصف الملف: text

العلاقة: https://vuir.vu.edu.au/45304Test/; https://doi.org/10.1038/s41467-017-02083-1Test; https://vuir.vu.edu.au/45304/1/Malaria%20parasite%20DNA-harbouring%20vesicles%20activate%20cytosolic%20immune%20sensors.pdfTest; Sisquella, Xavier, Ofir-Birin, Yifat, Pimentel, Matthew A, Cheng, Lesley, Abou Karam, Paula, Sampaio, Natalia G, Penington, Jocelyn Sietsma, Connolly, Dympna, Giladi, Tal, Scicluna, Benjamin J, Sharples, Robyn A, Waltmann, Andreea, Avni, Dror, Schwartz, Eli, Schofield, Louis, Porat, Ziv, Hansen, Diana S, Papenfuss, Anthony T, Eriksson, Emily M, Gerlic, Motti, Hill, Andrew F orcid:0000-0001-5581-2354 , Bowie, Andrew G and Regev-Rudzki, Neta (2017) Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors. Nature Communications, 8. ISSN 2041-1723

الإتاحة: https://doi.org/10.1038/s41467-017-02083-1Test
https://vuir.vu.edu.au/45304Test/
https://www.nature.com/articles/s41467-017-02083-1Test
https://vuir.vu.edu.au/45304/1/Malaria%20parasite%20DNA-harbouring%20vesicles%20activate%20cytosolic%20immune%20sensors.pdfTest

المؤلفون: Almine, Jessica F., O'Hare, Craig A. J., Dunphy, Gillian, Haga, Ismar R., Naik, Rangeetha J., Atrih, Abdelmadjid, Connolly, Dympna J., Taylor, Jordan, Kelsall, Ian R., Bowie, Andrew G., Beard, Philippa M., Unterholzner, Leonie

المصدر: Almine , J F , O'Hare , C A J , Dunphy , G , Haga , I R , Naik , R J , Atrih , A , Connolly , D J , Taylor , J , Kelsall , I R , Bowie , A G , Beard , P M & Unterholzner , L 2017 , ' IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes ' , Nature Communications , vol. 8 , 14392 , pp. 1-15 . https://doi.org/10.1038/ncomms14392Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/ae76526a-3adb-4dae-aa04-ab4e737516f0Test

الإتاحة: https://doi.org/10.1038/ncomms14392Test
https://discovery.dundee.ac.uk/en/publications/ae76526a-3adb-4dae-aa04-ab4e737516f0Test
https://discovery.dundee.ac.uk/ws/files/11996728/ncomms14392.pdfTest

المؤلفون: Dowling, Jennifer K., Becker, Christine E., Bourke, Nollaig M., Corr, Sinead C., Connolly, Dympna J., Quinn, Susan R., Pandolfi, Paolo P., Mansell, Ashley, O'Neill, Luke A.J.

المصدر: Journal of Biological Chemistry ; volume 289, issue 10, page 6429-6437 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.m113.539692Test
https://api.elsevier.com/content/article/PII:S0021925820444655?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925820444655?httpAccept=text/plainTest

المؤلفون: Connolly, Dympna J., O'Neill, Luke A.J., McGettrick, Anne F.

المصدر: Journal of Biological Chemistry ; volume 288, issue 8, page 5616-5623 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.m112.403899Test
https://api.elsevier.com/content/article/PII:S002192582045063X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S002192582045063X?httpAccept=text/plainTest

المؤلفون: Doyle, Sarah L., Husebye, Harald, Connolly, Dympna J., Espevik, Terje, O'Neill, Luke A.J., McGettrick, Anne F.

المصدر: Nature Communications ; volume 3, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/ncomms1706Test
https://www.nature.com/articles/ncomms1706Test
https://www.nature.com/articles/ncomms1706.pdfTest

المؤلفون: Stack, Julianne, Doyle, Sarah L, Connolly, Dympna J, Reinert, Line S, O'Keeffe, Kate M, McLoughlin, Rachel M, Paludan, Søren R, Bowie, Andrew G

المصدر: Stack , J , Doyle , S L , Connolly , D J , Reinert , L S , O'Keeffe , K M , McLoughlin , R M , Paludan , S R & Bowie , A G 2014 , ' TRAM is required for TLR2 endosomal signaling to type I IFN induction ' , Journal of Immunology , vol. 193 , no. 12 , pp. 6090-102 . https://doi.org/10.4049/jimmunol.1401605Test

مصطلحات موضوعية: Adaptor Proteins, Signal Transducing, Cell Line, Endocytosis, Endosomes, Host-Pathogen Interactions, Humans, Immunity, Innate, Interferon Regulatory Factor-7, Interferon Type I, Interferon-beta, Intracellular Space, Membrane Glycoproteins, Myeloid Differentiation Factor 88, Peptides, Protein Binding, Protein Transport, Receptors, Interleukin-1, Signal Transduction, Toll-Like Receptor 2, Toll-Like Receptor 4

الإتاحة: https://doi.org/10.4049/jimmunol.1401605Test
https://pure.au.dk/portal/da/publications/tram-is-required-for-tlr2-endosomal-signaling-to-type-i-ifn-inductionTest(4ef250c9-2fe3-488b-b103-ae8f664c1de6).html

المؤلفون: Connolly, Dympna J., Bowie, Andrew G.

المساهمون: Science Foundation Ireland, National Institutes of Health

المصدر: Biochemical Pharmacology ; volume 92, issue 3, page 405-414 ; ISSN 0006-2952

مصطلحات موضوعية: Pharmacology, Biochemistry

الإتاحة: https://doi.org/10.1016/j.bcp.2014.08.031Test
https://api.elsevier.com/content/article/PII:S0006295214005218?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0006295214005218?httpAccept=text/plainTest