المؤلفون: Sacher, Adrian, LoRusso, Patricia, Patel, Manish R, Miller, Wilson H, Garralda, Elena, Forster, Martin D, Santoro, Armando, Falcon, Alejandro, Kim, Tae Won, Paz-Ares, Luis, Bowyer, Samantha, de Miguel, Maria, Han, Sae-Won, Krebs, Matthew G, Lee, Jong-Seok, Cheng, Michael L, Arbour, Kathryn, Massarelli, Erminia, Choi, Yoonha, Shi, Zhen, Mandlekar, Sandhya, Lin, Mark T, Royer-Joo, Stephanie, Chang, Julie, Dharia, Neekesh V, Schutzman, Jennifer L, Desai, Jayesh

المساهمون: Freres, Pierre

المصدر: New England Journal of Medicine, 389 (8), 710 - 721 (2023-08-24)

مصطلحات موضوعية: Antineoplastic Agents, KRAS protein, human, Proto-Oncogene Proteins p21(ras), Enzyme Inhibitors, Humans, Mutation, Proto-Oncogene Proteins p21(ras)/genetics, Administration, Oral, Antineoplastic Agents/administration & dosage, Antineoplastic Agents/adverse effects, Antineoplastic Agents/therapeutic use, Carcinoma, Non-Small-Cell Lung/drug therapy, Carcinoma, Non-Small-Cell Lung/genetics, Colorectal Neoplasms/drug therapy, Colorectal Neoplasms/genetics, Lung Neoplasms/drug therapy, Lung Neoplasms/genetics, Enzyme Inhibitors/administration & dosage, Enzyme Inhibitors/adverse effects, Enzyme Inhibitors/therapeutic use, Cancer, Gastroenterology, Gastrointestinal Tract Cancer, Genetics, Hematology/Oncology, Lung Cancer, Pulmonary/Critical Care, Pulmonary/Critical Care General, Treatments in Oncology, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Lung Neoplasms, Medicine (all), General Medicine, Human health sciences, Oncology, Sciences de la santé humaine, Oncologie

العلاقة: http://www.nejm.org/doi/pdf/10.1056/NEJMoa2303810Test; urn:issn:0028-4793; urn:issn:1533-4406

الوصول الحر: https://orbi.uliege.be/handle/2268/311523Test

المؤلفون: Georgiou, Alexandros

المساهمون: Banerji, U.

مصطلحات موضوعية: Colorectal Cancer--Therapy, Colorectal Neoplasms--Genetics

الوصول الحر: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.857299Test

المساهمون: Kyukwang Kim, Mooyoung Kim, Andrew J Lee, Sang-Hyun Song, Jun-Kyu Kang, Junghyun Eom, Gyeong Hoon Kang, Jeong Mo Bae, Sunwoo Min, Yeonsoo Kim, Yoojoo Lim, Han Sang Kim, Young-Joon Kim, Tae-You Kim, Inkyung Jung, Kim, Han Sang

مصطلحات موضوعية: Chromatin, Colorectal Neoplasms* / genetics, DNA, Genome, Humans, Prognosis, 3D cancer genome, CP: Cancer, CP: Genomics, clonality, colorectal cancer, enhancer-hijacking, in situ Hi-C, prognostic marker, structural variations

العلاقة: CELL REPORTS; J00488; OAK-2023-02725; https://ir.ymlib.yonsei.ac.kr/handle/22282913/196163Test; T202304563; CELL REPORTS, Vol.42(7) : 112778, 2023-07

الإتاحة: https://doi.org/10.1016/j.celrep.2023.112778Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/196163Test

المساهمون: Ceres Fernandez-Rozadilla, Maria Timofeeva, Zhishan Chen, Philip Law, Minta Thomas, Stephanie Schmit, Virginia Díez-Obrero, Li Hsu, Juan Fernandez-Tajes, Claire Palles, Kitty Sherwood, Sarah Briggs, Victoria Svinti, Kevin Donnelly, Susan Farrington, James Blackmur, Peter Vaughan-Shaw, Xiao-Ou Shu, Jirong Long, Qiuyin Cai, Xingyi Guo, Yingchang Lu, Peter Broderick, James Studd, Jeroen Huyghe, Tabitha Harrison, David Conti, Christopher Dampier, Mathew Devall, Fredrick Schumacher, Marilena Melas, Gad Rennert, Mireia Obón-Santacana, Vicente Martín-Sánchez, Ferran Moratalla-Navarro, Jae Hwan Oh, Jeongseon Kim, Sun Ha Jee, Keum Ji Jung, Sun-Seog Kweon, Min-Ho Shin, Aesun Shin, Yoon-Ok Ahn, Dong-Hyun Kim, Isao Oze, Wanqing Wen, Keitaro Matsuo, Koichi Matsuda, Chizu Tanikawa, Zefang Ren, Yu-Tang Gao, Wei-Hua Jia, John Hopper, Mark Jenkins, Aung Ko Win, Rish Pai, Jane Figueiredo, Robert Haile, Steven Gallinger, Michael Woods, Polly Newcomb, David Duggan, Jeremy Cheadle, Richard Kaplan, Timothy Maughan, Rachel Kerr, David Kerr, Iva Kirac, Jan Böhm, Lukka-Pekka Mecklin, Pekka Jousilahti, Paul Knekt, Lauri Aaltonen, Harri Rissanen, Eero Pukkala, Johan Eriksson, Tatiana Cajuso, Ulrika Hänninen, Johanna Kondelin, Kimmo Palin, Tomas Tanskanen, Laura Renkonen-Sinisalo, Brent Zanke, Satu Männistö, Demetrius Albanes, Stephanie Weinstein, Edward Ruiz-Narvaez, Julie Palmer, Daniel Buchanan, Elizabeth Platz, Kala Visvanathan, Cornelia Ulrich, Erin Siegel, Stefanie Brezina, Andrea Gsur, Peter Campbell, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Martha Slattery

مصطلحات موضوعية: Colorectal Neoplasms* / genetics, East Asian People* / genetics, European People* / genetics, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Multiomics, Polymorphism, Single Nucleotide / genetics

العلاقة: NATURE GENETICS; J02294; OAK-2023-02622; OAK-2023-02623; https://ir.ymlib.yonsei.ac.kr/handle/22282913/196118Test; T202302780; NATURE GENETICS, Vol.55(1) : 89-99, 2023-01

الإتاحة: https://doi.org/10.1038/s41588-022-01222-9Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/196118Test

المساهمون: Soyoung Kim, Jae-Hoon Lee, Eun Jung Park, Hye Sun Lee, Seung Hyuk Baik, Tae Joo Jeon, Kang Young Lee, Young Hoon Ryu, Jeonghyun Kang, Kang, Jeonghyun

مصطلحات موضوعية: Colorectal Neoplasms* / diagnostic imaging, Colorectal Neoplasms* / genetics, Fluorodeoxyglucose F18, Humans, Machine Learning, Microsatellite Instability, Positron Emission Tomography Computed Tomography, Retrospective Studies, Colorectal cancer, image analysis, positron emission tomography

وصف الملف: application/pdf

العلاقة: YONSEI MEDICAL JOURNAL; J02813; OAK-2023-01631; OAK-2023-01632; OAK-2023-01633; OAK-2023-01634; OAK-2023-01635; OAK-2023-01636; OAK-2023-01637; https://ir.ymlib.yonsei.ac.kr/handle/22282913/195385Test; T202303056; YONSEI MEDICAL JOURNAL, Vol.64(5) : 320-326, 2023-05

الإتاحة: https://doi.org/10.3349/ymj.2022.0548Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/195385Test

المؤلفون: Marolleau, Pauline, Tougeron, David, Allignet, Benoit, Cohen, Romain, Sefrioui, David, Gallet, Blandine, Dumont, Frédéric, Guimbaud, Rosine, Alouani, Emily, Passot, Guillaume, Desolneux, Grégoire, Ghiringhelli, François, Marchal, Frédéric, Mourthadhoi, Farouk, Coriat, Romain, Desgrippes, Romain, Locher, Christophe, Goujon, Gaël, Des Guetz, Gaëtan, Aparicio, Thomas, Paubelle, Etienne, Dupré, Aurélien, de la Fouchardière, Christelle

المساهمون: Centre Léon Bérard Lyon, Centre hospitalier universitaire de Poitiers = Poitiers University Hospital (CHU de Poitiers La Milétrie ), Université de Poitiers = University of Poitiers (UP), Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Saint-Antoine AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Génomique et Médecine Personnalisée du Cancer et des Maladies Neuropsychiatriques (GPMCND), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Rouen, Normandie Université (NU), UNICANCER - Institut régional du Cancer Montpellier Val d'Aurelle (ICM), CRLCC Val d'Aurelle - Paul Lamarque, Institut de Cancérologie de l'Ouest Angers/Nantes (UNICANCER/ICO), UNICANCER, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Lyon Sud CHU - HCL (CHLS), Hospices Civils de Lyon (HCL), Institut Bergonié Bordeaux, Département d'oncologie médicale Centre Georges-François Leclerc, Centre Régional de Lutte contre le cancer Georges-François Leclerc Dijon (UNICANCER/CRLCC-CGFL), UNICANCER-UNICANCER, Institut de Cancérologie de Lorraine - Alexis Vautrin Nancy (UNICANCER/ICL), Centre Hospitalier Universitaire de Saint-Etienne CHU Saint-Etienne (CHU ST-E), Université Jean Monnet - Saint-Étienne (UJM), Université Paris Descartes - Paris 5 (UPD5), Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CH de Saint-Malo Broussais, Centre Hospitalier de Meaux, AP-HP - Hôpital Bichat - Claude Bernard Paris, Hopital Saint-Louis AP-HP (AP-HP), CHU Amiens-Picardie, HEMATIM - Hématopoïèse et immunologie - UR UPJV 4666 (HEMATIM), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Paoli-Calmettes (IPC), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)

المصدر: ISSN: 0020-7136.

مصطلحات موضوعية: deficient mismatch repair system, immune checkpoint inhibitors, metastatic colorectal cancer, microsatellite instability, neoadjuvant treatment, pathological complete response, MESH: Colonic Neoplasms* / pathology, MESH: Colorectal Neoplasms* / drug therapy, MESH: Colorectal Neoplasms* / genetics, MESH: DNA Mismatch Repair / genetics, MESH: Humans, MESH: Immune Checkpoint Inhibitors / therapeutic use, MESH: Microsatellite Instability, MESH: Neoplasm Recurrence, Local / pathology, MESH: Rectal Neoplasms* / drug therapy, MESH: Retrospective Studies, [SDV.CAN]Life Sciences [q-bio]/Cancer

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37403609; hal-04154476; https://u-picardie.hal.science/hal-04154476Test; https://u-picardie.hal.science/hal-04154476/documentTest; https://u-picardie.hal.science/hal-04154476/file/Intl%20Journal%20of%20Cancer%20-%202023%20-%20Marolleau%20-%20Complete%20pathological%20response%20after%20chemotherapy%20or%20immune%20checkpoint.pdfTest; PUBMED: 37403609

الإتاحة: https://doi.org/10.1002/ijc.34636Test
https://u-picardie.hal.science/hal-04154476Test
https://u-picardie.hal.science/hal-04154476/documentTest
https://u-picardie.hal.science/hal-04154476/file/Intl%20Journal%20of%20Cancer%20-%202023%20-%20Marolleau%20-%20Complete%20pathological%20response%20after%20chemotherapy%20or%20immune%20checkpoint.pdfTest

المؤلفون: KONCINA, Eric, NURMIK, Martin, POZDEEV, Vitaly, GILSON, Cédric, TSENKOVA, Mina, BEGAJ, Rubens, Stang, S, GAIGNEAUX, Anthoula, Weindorfer, C, RODRIGUEZ, Fabien, SCHMOETTEN, Maryse, KLEIN, Eliane, KARTA, Jessica, Atanasova, V S, GRZYB, Kamil, ULLMANN, Pit, HALDER, Rashi, Hengstschläger, M, Graas, J, Augendre, V, Karapetyan, Y E, KERGER, Lucien, Zuegel, N, SKUPIN, Alexander, HAAN, Serge, MEISER, Johannes, Dolznig, H, LETELLIER, Elisabeth

المصدر: Nature Communications, 14 (1), 4251 (2023-07-17)

مصطلحات موضوعية: IL1R1 protein, human, Receptors, Interleukin-1 Type I, Humans, Fibroblasts/pathology, Immune Tolerance, Immunosuppression Therapy, Tumor Microenvironment, Cell Proliferation, Interleukin-1 Type I/genetics, Cancer-Associated Fibroblasts/pathology, Colorectal Neoplasms/drug therapy, Colorectal Neoplasms/genetics, Cancer-Associated Fibroblasts, Colorectal Neoplasms, Fibroblasts, Chemistry (all), Biochemistry, Genetics and Molecular Biology (all), Physics and Astronomy (all), General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary, Life sciences, biophysics & molecular biology, Sciences du vivant, Biochimie

العلاقة: https://www.nature.com/articles/s41467-023-39953-w.pdfTest; urn:issn:2041-1723; https://orbilu.uni.lu/handle/10993/60466Test; info:hdl:10993/60466; https://orbilu.uni.lu/bitstream/10993/60466/1/Koncina%20et%20al%2c%202023.pdfTest; scopus-id:2-s2.0-85165029123; info:pmid:37460545; wos:001032761800007

الإتاحة: https://doi.org/10.1038/s41467-023-39953-wTest
https://orbilu.uni.lu/handle/10993/60466Test
https://orbilu.uni.lu/bitstream/10993/60466/1/Koncina%20et%20al%2c%202023.pdfTest

المصدر: The PRACTICAL Consortium 2023 , ' Genetically proxied glucose-lowering drug target perturbation and risk of cancer : a Mendelian randomisation analysis ' , Diabetologia , vol. 66 , no. 8 , pp. 1481-1500 . https://doi.org/10.1007/s00125-023-05925-4Test

مصطلحات موضوعية: ABCC8, Breast cancer, Colorectal cancer, GLP1R, Glucose-lowering drug targets, Mendelian randomisation, PPARG, Prostate cancer, Genome-Wide Association Study, Humans, Risk Factors, Colorectal Neoplasms/genetics, Male, Glucose, Polymorphism, Single Nucleotide/genetics, Diabetes Mellitus, Type 2/drug therapy, Prostatic Neoplasms/complications, Mendelian Randomization Analysis, Breast Neoplasms/genetics, PPAR gamma/genetics

العلاقة: https://pure.au.dk/portal/en/publications/ccc37670-0dee-479b-bd77-1f542cb4bd93Test

الإتاحة: https://doi.org/10.1007/s00125-023-05925-4Test
https://pure.au.dk/portal/en/publications/ccc37670-0dee-479b-bd77-1f542cb4bd93Test
http://www.scopus.com/inward/record.url?scp=85164210817&partnerID=8YFLogxKTest

المؤلفون: Fernandez-Rozadilla, Ceres, Timofeeva, Maria, Chen, Zhishan, Law, Philip, Thomas, Minta, Schmit, Stephanie, Díez-Obrero, Virginia, Hsu, Li, Fernandez-Tajes, Juan, Palles, Claire, Sherwood, Kitty, Briggs, Sarah, Svinti, Victoria, Donnelly, Kevin, Farrington, Susan, Blackmur, James, Vaughan-Shaw, Peter, Shu, Xiao ou, Long, Jirong, Cai, Qiuyin, Guo, Xingyi, Lu, Yingchang, Broderick, Peter, Studd, James, Huyghe, Jeroen, Harrison, Tabitha, Conti, David, Dampier, Christopher, Devall, Mathew, Schumacher, Fredrick, Melas, Marilena, Rennert, Gad, Obón-Santacana, Mireia, Martín-Sánchez, Vicente, Moratalla-Navarro, Ferran, Oh, Jae Hwan, Kim, Jeongseon, Jee, Sun Ha, Jung, Keum Ji, Kweon, Sun Seog, Shin, Min Ho, Shin, Aesun, Ahn, Yoon Ok, Kim, Dong Hyun, Oze, Isao, Wen, Wanqing, Matsuo, Keitaro, Matsuda, Koichi, Tanikawa, Chizu, Ren, Zefang, Gao, Yu Tang, Jia, Wei Hua, Hopper, John, Jenkins, Mark, Win, Aung Ko, Pai, Rish, Figueiredo, Jane, Haile, Robert, Gallinger, Steven, Woods, Michael, Newcomb, Polly, Duggan, David, Cheadle, Jeremy, Kaplan, Richard, Maughan, Timothy, Kerr, Rachel, Kerr, David, Kirac, Iva, Böhm, Jan, Mecklin, Lukka Pekka, Jousilahti, Pekka, Knekt, Paul, Aaltonen, Lauri, Rissanen, Harri, Pukkala, Eero, Eriksson, Johan, Cajuso, Tatiana, Hänninen, Ulrika, Kondelin, Johanna, Palin, Kimmo, Tanskanen, Tomas, Renkonen-Sinisalo, Laura, Zanke, Brent, Männistö, Satu, Albanes, Demetrius, Weinstein, Stephanie, Ruiz-Narvaez, Edward, Palmer, Julie, Buchanan, Daniel, Platz, Elizabeth, Visvanathan, Kala, Ulrich, Cornelia, Siegel, Erin, Brezina, Stefanie, Gsur, Andrea, Campbell, Peter, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Slattery, Martha, Potter, John, Tsilidis, Konstantinos, Schulze, Matthias, Gunter, Marc, Murphy, Neil, Castells, Antoni, Castellví-Bel, Sergi, Moreira, Leticia, Arndt, Volker, Shcherbina, Anna, Stern, Mariana, Pardamean, Bens, Bishop, Timothy, Giles, Graham, Southey, Melissa, Idos, Gregory, McDonnell, Kevin, Abu-Ful, Zomoroda, Greenson, Joel, Shulman, Katerina, Lejbkowicz, Flavio, Offit, Kenneth, Su, Yu Ru, Steinfelder, Robert, Keku, Temitope, van Guelpen, Bethany, Hudson, Thomas, Hampel, Heather, Pearlman, Rachel, Berndt, Sonja, Hayes, Richard, Martinez, Marie Elena, Thomas, Sushma, Corley, Douglas, Pharoah, Paul, Larsson, Susanna, Yen, Yun, Lenz, Heinz Josef, White, Emily, Li, Li, Doheny, Kimberly, Pugh, Elizabeth, Shelford, Tameka, Chan, Andrew, Cruz-Correa, Marcia, Lindblom, Annika, Hunter, David, Joshi, Amit, Schafmayer, Clemens, Scacheri, Peter, Kundaje, Anshul, Nickerson, Deborah, Schoen, Robert, Hampe, Jochen, Stadler, Zsofia, Vodicka, Pavel, Vodickova, Ludmila, Vymetalkova, Veronika, Papadopoulos, Nickolas, Edlund, Chistopher, Gauderman, William, Thomas, Duncan, Shibata, David, Toland, Amanda, Markowitz, Sanford, Kim, Andre, Chanock, Stephen, van Duijnhoven, Franzel, Feskens, Edith, Sakoda, Lori, Gago-Dominguez, Manuela, Wolk, Alicja, Naccarati, Alessio, Pardini, Barbara, FitzGerald, Liesel, Lee, Soo Chin, Ogino, Shuji, Bien, Stephanie, Kooperberg, Charles, Li, Christopher, Lin, Yi, Prentice, Ross, Qu, Conghui, Bézieau, Stéphane, Tangen, Catherine, Mardis, Elaine, Yamaji, Taiki, Sawada, Norie, Iwasaki, Motoki, Haiman, Christopher, Le Marchand, Loic, Wu, Anna, Qu, Chenxu, McNeil, Caroline, Coetzee, Gerhard, Hayward, Caroline, Deary, Ian, Harris, Sarah, Theodoratou, Evropi, Reid, Stuart, Walker, Marion, Ooi, Li Yin, Moreno, Victor, Casey, Graham, Gruber, Stephen, Tomlinson, Ian, Zheng, Wei, Dunlop, Malcolm, Houlston, Richard, Peters, Ulrike

المصدر: Fernandez-Rozadilla , C , Timofeeva , M , Chen , Z , Law , P , Thomas , M , Schmit , S , Díez-Obrero , V , Hsu , L , Fernandez-Tajes , J , Palles , C , Sherwood , K , Briggs , S , Svinti , V , Donnelly , K , Farrington , S , Blackmur , J , Vaughan-Shaw , P , Shu , X O , Long , J , Cai , Q , Guo , X , Lu , Y , Broderick , P , Studd , J , Huyghe , ....

مصطلحات موضوعية: Colorectal Neoplasms/genetics, East Asian People/genetics, European People/genetics, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Multiomics, Polymorphism, Single Nucleotide/genetics

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/6611e9c2-5392-4b94-bd23-1bcac0010cb4Test

الإتاحة: https://doi.org/10.1038/s41588-022-01222-9Test
https://doi.org/10.1038/s41588-023-01334-wTest
https://portal.findresearcher.sdu.dk/da/publications/6611e9c2-5392-4b94-bd23-1bcac0010cb4Test
https://findresearcher.sdu.dk/ws/files/226512438/62499_2_merged_1665683535.pdfTest
https://findresearcher.sdu.dk/ws/files/226512440/SuppTables_110422.xlsxTest
https://findresearcher.sdu.dk/ws/files/226512442/62499_2_supp_707822_rbznjt_convrt.pdfTest

المؤلفون: Zhou, Xuan, Xiao, Qian, Jiang, Fangyuan, Sun, Jing, Wang, Lijuan, Yu, Lili, Zhou, Yajing, Zhao, Jianhui, Zhang, Han, Yuan, Shuai, Timofeeva, Maria, Spiliopoulou, Athina, Mesa-Eguiagaray, Ines, Farrington, Susan M., Law, Philip J., Houlston, Richard S., Ding, Kefeng, Dunlop, Malcolm G., Theodoratou, Evropi, Li, Xue

المصدر: Zhou , X , Xiao , Q , Jiang , F , Sun , J , Wang , L , Yu , L , Zhou , Y , Zhao , J , Zhang , H , Yuan , S , Timofeeva , M , Spiliopoulou , A , Mesa-Eguiagaray , I , Farrington , S M , Law , P J , Houlston , R S , Ding , K , Dunlop , M G , Theodoratou , E & Li , X 2023 , ' Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation ....

مصطلحات موضوعية: Colorectal Neoplasms/genetics, DNA Methylation, Genome-Wide Association Study, Humans, Polymorphism, Single Nucleotide, Prospective Studies, Smoking/adverse effects, Tobacco Smoking

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/f4b0af50-8203-4c87-b378-5f9ecc55541dTest

الإتاحة: https://doi.org/10.1038/s41416-023-02397-6Test
https://portal.findresearcher.sdu.dk/da/publications/f4b0af50-8203-4c87-b378-5f9ecc55541dTest
https://findresearcher.sdu.dk/ws/files/254745159/s41416-023-02397-6.pdfTest