دورية أكاديمية
Biological Therapies or Apremilast in the Treatment of Psoriasis in Patients with a History of Hematologic Malignancy: Results from a Retrospective Study in 21 Patients
| العنوان: | Biological Therapies or Apremilast in the Treatment of Psoriasis in Patients with a History of Hematologic Malignancy: Results from a Retrospective Study in 21 Patients |
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| المؤلفون: | Cohen-Sors,Raphaella, Fougerousse,Anne-Claire, Reguiai,Ziad, Maccari,Francois, Mahé,Emmanuel, Delaunay,Juliette, Roussel,Aude, de la Breteque,Maud Amy, Cottencin,Caroline, Bertolotti,Antoine, Kemp,Hélène, Chaby,Guillaume |
| بيانات النشر: | Dove Press |
| سنة النشر: | 2021 |
| المجموعة: | Dove Medical Press |
| مصطلحات موضوعية: | Clinical, Cosmetic and Investigational Dermatology |
| الوصف: | Raphaella Cohen-Sors,1 Anne-Claire Fougerousse,2 Ziad Reguiai,3 Francois Maccari,2 Emmanuel Mahé,4 Juliette Delaunay,5 Aude Roussel,2 Maud Amy de la Breteque,4 Caroline Cottencin,6 Antoine Bertolotti,7 Hélène Kemp,8 Guillaume Chaby1 1Dermatology Department, Amiens-Picardie University Hospital Center, Amiens, France; 2Dermatology Department, Military Teaching Hospital Bégin, Saint-Mandé, France; 3Dermatology Department, Polyclinic Courlancy, Reims, France; 4Dermatology Department, Argenteuil Hospital, Argenteuil, France; 5Dermatology Department, University Hospital, Angers, France; 6Dermatology Department, University Hospital, Lille, France; 7Dermatology Department, University Hospital, Saint-Pierre, Ile de la Réunion, France; 8Hematology Department, Amiens-Picardie University Hospital Center, Amiens, FranceCorrespondence: Guillaume Chaby Email chaby.guillaume@chu-amiens.frBackground: Few studies addressing the safety and efficacy of biological therapy (BT) or apremilast (APR) in patients with psoriasis with a history of hematologic malignancy (HM) exist.Aim: To describe the tolerance and efficacy of BT and APR in moderate-to-severe psoriasis in patients with a history of in-remission or evolving HM.Methodology: A retrospective, multicenter chart review of the tolerance and efficacy of BT or APR in patients with moderate-to-severe psoriasis and a clinical history of in-remission or evolving HM.Results: Twenty-one patients with severe psoriasis and a history of HM were included in France by the GEM Resopso study group. Of the 16 patients treated with one or more BT lines, none showed recurrence of their HM which was considered as stable or in remission, and only 2 patients showed an evolution of their HM which had been considered as stable at the beginning of treatment. In the 10 patients treated with APR, the HM of one patient who also received BT worsened. The 3 evolutions did not impact the treatment with BT or APR. Tolerance was very satisfactory, with a low occurrence of infections. Regarding efficacy, ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | https://www.dovepress.com/biological-therapies-or-apremilast-in-the-treatment-of-psoriasis-in-pa-peer-reviewed-fulltext-article-CCIDTest |
| الإتاحة: | https://doi.org/10.2147/CCID.S320098Test https://www.dovepress.com/biological-therapies-or-apremilast-in-the-treatment-of-psoriasis-in-pa-peer-reviewed-fulltext-article-CCIDTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.EA1030AF |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |