المؤلفون: Schoof, Michael, Wang, Lan, Cogan, J Zachery, Lawrence, Rosalie E, Boone, Morgane, Wuerth, Jennifer Deborah, Frost, Adam, Walter, Peter

المصدر: Nature communications. 12(1)

مصطلحات موضوعية: K562 Cells, Humans, Phlebovirus, Virus Diseases, Eukaryotic Initiation Factor-2B, Eukaryotic Initiation Factor-2, Viral Proteins, Cryoelectron Microscopy, Binding Sites, Protein Binding, Phosphorylation, Infectious Diseases, Emerging Infectious Diseases, Genetics, Infection, Generic health relevance

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8rh3r2b3Test

المؤلفون: Nuñez, James K, Chen, Jin, Pommier, Greg C, Cogan, J Zachery, Replogle, Joseph M, Adriaens, Carmen, Ramadoss, Gokul N, Shi, Quanming, Hung, King L, Samelson, Avi J, Pogson, Angela N, Kim, James YS, Chung, Amanda, Leonetti, Manuel D, Chang, Howard Y, Kampmann, Martin, Bernstein, Bradley E, Hovestadt, Volker, Gilbert, Luke A, Weissman, Jonathan S

المصدر: Cell. 184(9)

مصطلحات موضوعية: Biological Sciences, Genetics, Human Genome, Biotechnology, Stem Cell Research, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, CRISPR-Cas Systems, Cell Differentiation, Cellular Reprogramming, CpG Islands, DNA Methylation, Epigenesis, Genetic, Epigenome, Gene Editing, Gene Silencing, Histone Code, Humans, Induced Pluripotent Stem Cells, Neurons, Protein Processing, Post-Translational, CRISPR, DNA methylation, cell therapy, dCas9, epigenetics, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4ph8w0v1Test
https://escholarship.org/content/qt4ph8w0v1/qt4ph8w0v1.pdfTest

المؤلفون: Hickey, Kelsey L, Dickson, Kimberley, Cogan, J Zachery, Replogle, Joseph M, Schoof, Michael, D'Orazio, Karole N, Sinha, Niladri K, Hussmann, Jeffrey A, Jost, Marco, Frost, Adam, Green, Rachel, Weissman, Jonathan S, Kostova, Kamena K

المصدر: Molecular cell. 79(6)

مصطلحات موضوعية: Ribosomes, Animals, Humans, Mice, Ubiquitin-Protein Ligases, Carrier Proteins, Eukaryotic Initiation Factor-4E, RNA, Messenger, Protein Biosynthesis, Protein Processing, Post-Translational, Peptide Chain Initiation, Translational, Quality Control, CRISPR-Cas Systems, Neurodegenerative, Genetics, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0wp752dkTest

المؤلفون: Replogle, Joseph M, Norman, Thomas M, Xu, Albert, Hussmann, Jeffrey A, Chen, Jin, Cogan, J Zachery, Meer, Elliott J, Terry, Jessica M, Riordan, Daniel P, Srinivas, Niranjan, Fiddes, Ian T, Arthur, Joseph G, Alvarado, Luigi J, Pfeiffer, Katherine A, Mikkelsen, Tarjei S, Weissman, Jonathan S, Adamson, Britt

المصدر: Nature Biotechnology. 38(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Human Genome, Biotechnology, Prevention, Generic health relevance, CRISPR-Cas Systems, Gene Expression Regulation, Gene Targeting, HEK293 Cells, High-Throughput Nucleotide Sequencing, Humans, Nucleic Acid Amplification Techniques, RNA, Guide, Kinetoplastida, Single-Cell Analysis, Transcriptome

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5tw9z723Test

المؤلفون: Chen, Jin, Brunner, Andreas-David, Cogan, J Zachery, Nuñez, James K, Fields, Alexander P, Adamson, Britt, Itzhak, Daniel N, Li, Jason Y, Mann, Matthias, Leonetti, Manuel D, Weissman, Jonathan S

المصدر: Science. 367(6482)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Prevention, Biodefense, Vaccine Related, Human Genome, Biotechnology, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, CRISPR-Cas Systems, Humans, Open Reading Frames, Operon, Peptides, Protein Biosynthesis, RNA, Messenger, Ribosomes, Transcriptome, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/96m1n5z5Test

المؤلفون: Nuñez, James K, Chen, Jin, Pommier, Greg C, Cogan, J Zachery, Replogle, Joseph M, Adriaens, Carmen, Ramadoss, Gokul N, Shi, Quanming, Hung, King L, Samelson, Avi J, Pogson, Angela N, Kim, James YS, Chung, Amanda, Leonetti, Manuel D, Chang, Howard Y, Kampmann, Martin, Bernstein, Bradley E, Hovestadt, Volker, Gilbert, Luke A, Weissman, Jonathan S

المساهمون: Whitehead Institute for Biomedical Research

المصدر: PMC

وصف الملف: application/octet-stream

العلاقة: http://dx.doi.org/10.1016Test/J.CELL.2021.03.025; Cell; https://hdl.handle.net/1721.1/142534.2Test; Nuñez, James K, Chen, Jin, Pommier, Greg C, Cogan, J Zachery, Replogle, Joseph M et al. 2021. "Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing." Cell, 184 (9).

الإتاحة: https://doi.org/10.1016Test/J.CELL.2021.03.025
https://hdl.handle.net/1721.1/142534.2Test