المؤلفون: Adler, Benjamin A, Trinidad, Marena I, Bellieny-Rabelo, Daniel, Zhang, Elaine, Karp, Hannah M, Skopintsev, Petr, Thornton, Brittney W, Weissman, Rachel F, Yoon, Peter H, Chen, LinXing, Hessler, Tomas, Eggers, Amy R, Colognori, David, Boger, Ron, Doherty, Erin E, Tsuchida, Connor A, Tran, Ryan V, Hofman, Laura, Shi, Honglue, Wasko, Kevin M, Zhou, Zehan, Xia, Chenglong, Al-Shimary, Muntathar J, Patel, Jaymin R, Thomas, Vienna CJX, Pattali, Rithu, Kan, Matthew J, Vardapetyan, Anna, Yang, Alana, Lahiri, Arushi, Maxwell, Micaela F, Murdock, Andrew G, Ramit, Glenn C, Henderson, Hope R, Calvert, Roland W, Bamert, Rebecca S, Knott, Gavin J, Lapinaite, Audrone, Pausch, Patrick, Cofsky, Joshua C, Sontheimer, Erik J, Wiedenheft, Blake, Fineran, Peter C, Brouns, Stan JJ, Sashital, Dipali G, Thomas, Brian C, Brown, Christopher T, Goltsman, Daniela SA, Barrangou, Rodolphe, Siksnys, Virginius, Banfield, Jillian F, Savage, David F, Doudna, Jennifer A

المصدر: Nucleic Acids Research. 52(D1)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Humans, Bacteria, RNA, Phylogeny, CRISPR-Cas Systems, Gene Editing, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5ck3v1hwTest

المؤلفون: Cofsky, Joshua C, Soczek, Katarzyna M, Knott, Gavin J, Nogales, Eva, Doudna, Jennifer A

المصدر: Nature Structural & Molecular Biology. 29(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Biological Sciences, Genetics, Biotechnology, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, CRISPR-Cas Systems, DNA, Endonucleases, Gene Editing, RNA, Guide, Kinetoplastida, Chemical Sciences, Medical and Health Sciences, Biophysics, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/50v323sqTest

المؤلفون: Gao, Yongqiang, Amon, Jeremy D., Brogan, Anna P., Artzi, Lior, Ramírez-Guadiana, Fernando H., Cofsky, Joshua C., Kruse, Andrew C., Rudner, David Z.

مصطلحات موضوعية: Research Papers

وصف الملف: text/html

العلاقة: http://genesdev.cshlp.org/cgi/content/short/38/1-2/31Test; http://dx.doi.org/10.1101/gad.351353.123Test

الإتاحة: https://doi.org/10.1101/gad.351353.123Test
http://genesdev.cshlp.org/cgi/content/short/38/1-2/31Test

المؤلفون: Cofsky, Joshua C, Knott, Gavin J, Gee, Christine L, Doudna, Jennifer A

المصدر: PLOS ONE. 17(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, DNA, Nucleic Acid Conformation, Nucleic Acids, Nucleotides, RNA, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/54863152Test

المؤلفون: Ivanov, Ivan E, Wright, Addison V, Cofsky, Joshua C, Aris, Kevin D Palacio, Doudna, Jennifer A, Bryant, Zev

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(11)

مصطلحات موضوعية: Biochemistry and Cell Biology, Physical Sciences, Biological Sciences, Biotechnology, Genetics, Bioengineering, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Base Pairing, CRISPR-Associated Proteins, CRISPR-Cas Systems, DNA, DNA Cleavage, Endonucleases, Gene Editing, Genome, R-Loop Structures, RNA, RNA, Guide, Kinetoplastida, magnetic tweezers, gene editing, torque spectroscopy

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4x9506b9Test

المؤلفون: Cofsky, Joshua C, Karandur, Deepti, Huang, Carolyn J, Witte, Isaac P, Kuriyan, John, Doudna, Jennifer A

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Biological Sciences, Genetics, Prevention, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Bacterial Proteins, CRISPR-Associated Proteins, CRISPR-Cas Systems, DNA, DNA Breaks, Double-Stranded, Endodeoxyribonucleases, Escherichia coli, Gene Editing, R-Loop Structures, RNA, Guide, Kinetoplastida, CRISPR, E. coli, R-loop, RNA, biochemistry, chemical biology, deoxyribonuclease, genome editing, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6sq1v35sTest

المؤلفون: Cofsky, Joshua C, Doudna, Jennifer A

المصدر: Bio-protocol. 10(20)

مصطلحات موضوعية: Rare Diseases, Genetics, Generic health relevance, Radiolabel, P-32-phosphate, 3' DNA end, T4 polynucleotide kinase, T4 RNA ligase 2, DNA oligonucleotide, 2'-O-methylribonucleotide, 2', 3'-cyclic phosphate, 2′-O-methylribonucleotide, 2′, 32P-phosphate, 3′ DNA end, 3′-cyclic phosphate, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8x76b17dTest

المؤلفون: Adler, Benjamin A, Trinidad, Marena I, Bellieny-Rabelo, Daniel, Zhang, Elaine, Karp, Hannah M, Skopintsev, Petr, Thornton, Brittney W, Weissman, Rachel F, Yoon, Peter H, Chen, LinXing, Hessler, Tomas, Eggers, Amy R, Colognori, David, Boger, Ron, Doherty, Erin E, Tsuchida, Connor A, Tran, Ryan V, Hofman, Laura, Shi, Honglue, Wasko, Kevin M, Zhou, Zehan, Xia, Chenglong, Al-Shimary, Muntathar J, Patel, Jaymin R, Thomas, Vienna C J X, Pattali, Rithu, Kan, Matthew J, Vardapetyan, Anna, Yang, Alana, Lahiri, Arushi, Maxwell, Michaela F, Murdock, Andrew G, Ramit, Glenn C, Henderson, Hope R, Calvert, Roland W, Bamert, Rebecca S, Knott, Gavin J, Lapinaite, Audrone, Pausch, Patrick, Cofsky, Joshua C, Sontheimer, Erik J, Wiedenheft, Blake, Fineran, Peter C, Brouns, Stan J J, Sashital, Dipali G, Thomas, Brian C, Brown, Christopher T, Goltsman, Daniela S A, Barrangou, Rodolphe, Šikšnys, Virginijus, Banfield, Jillian F, Savage, David F, Doudna, Jennifer A

المصدر: Nucleic acids research., Oxford : Oxford University Press, 2024, vol. 52, iss. D1, p. D590-D596. ; ISSN 0305-1048 ; eISSN 1362-4962

مصطلحات موضوعية: CasPEDIA, CRISPR-Cas, Database

وصف الملف: application/pdf

العلاقة: https://epublications.vu.lt/object/elaba:181883712/181883712.pdfTest; https://repository.vu.lt/VU:ELABAPDB181883712&prefLang=en_USTest

الإتاحة: https://doi.org/10.1093/nar/gkad890Test
https://repository.vu.lt/VU:ELABAPDB181883712&prefLang=en_USTest

المؤلفون: Harrington, Lucas B, Doxzen, Kevin W, Ma, Enbo, Liu, Jun-Jie, Knott, Gavin J, Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Chen, Janice S, Cofsky, Joshua C, Kranzusch, Philip J, Sontheimer, Erik J, Davidson, Alan R, Maxwell, Karen L, Doudna, Jennifer A

المصدر: Cell. 170(6)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Prevention, Genetics, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Amino Acid Sequence, Bacterial Proteins, Bacteriophages, CRISPR-Cas Systems, Endonucleases, Evolution, Molecular, HEK293 Cells, Humans, Protein Domains, Sequence Alignment, Viral Proteins, CRISPR, CRISPR-Cas9, Cas9, anti-CRISPR, gene editing, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

الوصول الحر: https://escholarship.org/uc/item/3jx3d2pvTest

المؤلفون: Bandaru, Pradeep, Shah, Neel H, Bhattacharyya, Moitrayee, Barton, John P, Kondo, Yasushi, Cofsky, Joshua C, Gee, Christine L, Chakraborty, Arup K, Kortemme, Tanja, Ranganathan, Rama, Kuriyan, John

مصطلحات موضوعية: Humans, ras Proteins, DNA Mutational Analysis, Evolution, Molecular, Mutagenesis, Conserved Sequence, Protein Interaction Maps, E. coli, S. cerevisiae, allostery, biophysics, evolution, protein dynamics, structural biology, systems biology, Evolution, Molecular, Genetics, 1.1 Normal biological development and functioning, Generic Health Relevance, Biochemistry and Cell Biology

الوصول الحر: https://escholarship.org/uc/item/1gr1c2b5Test