التفاصيل البيبلوغرافية
| العنوان: |
GenPup-M: A novel validated owner-reported clinical metrology instrument for detecting early mobility changes in dogs |
| المؤلفون: |
Clark, Natasha L., Bates, Karl T., Harris, Lauren K., Tomlinson, Andrew W., Murray, Jane K., Comerford, Eithne J. |
| المساهمون: |
Loor, Juan J., Dogs Trust, Medical Research Council |
| المصدر: |
PLOS ONE ; volume 18, issue 12, page e0291035 ; ISSN 1932-6203 |
| بيانات النشر: |
Public Library of Science (PLoS) |
| سنة النشر: |
2023 |
| المجموعة: |
PLOS Publications (via CrossRef) |
| الوصف: |
Objective To use a previously validated veterinary clinical examination sheet, Liverpool Osteoarthritis in Dogs (LOAD) questionnaire, combined with kinetic and kinematic gait analysis in dogs with/without mobility problems to demonstrate the capacity of a novel clinical metrology instrument (“GenPup-M”) to detect canine mobility impairments. Design Quantitative study. Animals 62 dogs (31 with mobility impairments and 31 without mobility impairments). Procedure The dogs’ clinical history was obtained from owners and all dogs underwent a validated orthopaedic clinical examination. Mobility impairments were diagnosed in the mobility impaired group based on clinical history and orthopaedic examination. Owners were asked to complete GenPup-M along with a previously validated mobility questionnaire (Liverpool Osteoarthritis in Dogs (LOAD)) to identify construct validity. As a test of criterion validity, the correlation between instrument scores and the overall clinical examination scores, along with force-platform obtained peak vertical forces (PVF) were calculated. GenPup-M underwent internal consistency and factor analysis. Spatiotemporal parameters were calculated for dogs with/without mobility impairments to define the gait differences between these two groups. Results Principal Component Analysis identified GenPup-M had two components with Eigenvalues >1 (“stiffness/ease of movement” and “willingness to be active/exercise”). Cronbach’s α was used to test internal consistency of GenPup-M and was found to be “good” (0.87). There was a strong, positive correlation between GenPup-M and LOAD responses (r 2 = 0.69, p<0.001) highlighting construct validity. Criterion validity was also shown when comparing GenPup-M to clinical examination scores (r 2 = 0.74, p<0.001) and PVF (r 2 = 0.43, p<0.001). Quantitative canine gait analysis showed that there were statistically significant differences between peak vertical forces (PVF) of mobility impaired and non-mobility impaired dogs (p<0.05). Analyses of PVF ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1371/journal.pone.0291035 |
| الإتاحة: |
https://doi.org/10.1371/journal.pone.0291035Test |
| حقوق: |
http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.E13B1477 |
| قاعدة البيانات: |
BASE |
