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1دورية أكاديمية
المؤلفون: Yihua Lin, Yiling Zhao, Minggui Chen, Zishuo Li, Qiao Liu, Jian Chen, Yi Ding, Chunyong Ding, Ye Ding, Cuiling Qi, Lingyun Zheng, Jiangchao Li, Rongxin Zhang, Jia Zhou, Lijing Wang, Qian-Qian Zhang
المصدر: BMC Cancer, Vol 23, Iss 1, Pp 1-18 (2023)
مصطلحات موضوعية: CYD0281, B-cell lymphoma 2 (Bcl-2), Bcl-2 homology (BH) domains, BH4 domain antagonist, Apoptosis, Angiogenesis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1471-2407Test
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2دورية أكاديمية
المؤلفون: Heng Xu, Hongfang Zhao, Chunyong Ding, Defang Jiang, Zijie Zhao, Yang Li, Xiaoyu Ding, Jing Gao, Hu Zhou, Cheng Luo, Guoqiang Chen, Ao Zhang, Ying Xu, Hao Zhang
المصدر: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-16 (2023)
مصطلحات موضوعية: Medicine, Biology (General), QH301-705.5
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2059-3635Test
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3دورية أكاديمية
المؤلفون: Xiyuan Wang, Ancheng Shen, Yan Zhang, Xiaoxu Chen, Jian Ding, Ao Zhang, Meiyu Geng, Chunyong Ding, Zuoquan Xie
المصدر: Clinical and Translational Discovery, Vol 3, Iss 5, Pp n/a-n/a (2023)
مصطلحات موضوعية: anti‐tumor, combinatory therapy, immunotherapy, innate immunity, STING agonist, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2768-0622Test
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4دورية أكاديمية
المؤلفون: Xiaohua Liu, Yu Zhang, Yalei Li, Juan Wang, Huaqian Ding, Wenjing Huang, Chunyong Ding, Hongchun Liu, Wenfu Tan, Ao Zhang
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 488-504 (2021)
مصطلحات موضوعية: Medulloblastoma, Hedgehog signaling pathway, Drug resistance, GLI, BRD4, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S221138352030633XTest; https://doaj.org/toc/2211-3835Test
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5دورية أكاديمية
المؤلفون: Chunyong Ding, Zilan Song, Ancheng Shen, Tingting Chen, Ao Zhang
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2272-2298 (2020)
مصطلحات موضوعية: Immunotherapy, Anti-tumor, cGAS, STING, TBK1, Small molecule modulators, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S2211383519316946Test; https://doaj.org/toc/2211-3835Test
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6دورية أكاديمية
المؤلفون: Hongchuan Zhao, Pu Sun, Wei Guo, Yi Wang, Ao Zhang, Linghua Meng, Chunyong Ding
المصدر: Molecules, Vol 24, Iss 6, p 1059 (2019)
مصطلحات موضوعية: indoleamine 2,3-dioxygenase 1, immunosuppressive, natural product, ortho-naphthaquinone, molecular docking, Organic chemistry, QD241-441
وصف الملف: electronic resource
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7دورية أكاديمية
المؤلفون: Ruoqing Zeng, Meimiao Fang, Ancheng Shen, Xiaolei Chai, Yumiao Zhao, Mingyao Liu, Lingfeng Zhu, Weiwei Rui, Bo Feng, Liang Hong, Chunyong Ding, Zilan Song, Weiqiang Lu, Ao Zhang
مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Immunology, Cancer, Chemical Sciences not elsewhere classified, structural elaboration focusing, safety profile based, reference antagonist nibr189, inferior druglike properties, induced experimental colitis, robust antagonistic activity, critical pathological role, inflammatory bowel disease, oxysterol receptor gpr183, improved pk properties, 50 sub, 33 b, inflammatory activity, pathological symptoms, effectively improved, various inflammatory, vivo <, vitro <, studies due, oral administration, high selectivity, findings demonstrate, displayed strong, benzo [<
الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01905.s001Test
https://figshare.com/articles/journal_contribution/Discovery_of_a_Highly_Potent_Oxysterol_Receptor_GPR183_Antagonist_Bearing_the_Benzo_i_d_i_thiazole_Structural_Motif_for_the_Treatment_of_Inflammatory_Bowel_Disease_IBD_/25308386Test -
8دورية أكاديمية
المؤلفون: Xuanzheng Xiao, Juanjuan Feng, Jing Ma, Xinting Xia, Xiaogu Liu, Jian Zhang, Chunyong Ding, Xiufeng Pang, Ao Zhang
مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, kg twice daily, new compounds markedly, inhibitors provides inspiration, tumor growth inhibition, showed higher potency, new inhibitors call, g12d sup, g12c sup, 50 sub, new inhibitors, tumor efficacy, clonogenic growth, vivo <, vitro <, structural analysis, selectively inhibited, rbd peptide, pharmacological evaluation, p .), multisubstituted pyrido
الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01724.s001Test
https://figshare.com/articles/journal_contribution/Design_Synthesis_and_Pharmacological_Evaluation_of_Multisubstituted_Pyrido_4_3_i_d_i_pyrimidine_Analogues_Bearing_Deuterated_Methylene_Linkers_as_Potent_KRAS_sup_G12D_sup_Inhibitors/24495049Test -
9دورية أكاديمية
المؤلفون: Chenghu Xie, Bo Liu, Zilan Song, Ye Yang, Mengdi Dai, Yinglei Gao, Yujia Yao, Chunyong Ding, Jing Ai, Ao Zhang
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Virology, Chemical Sciences not elsewhere classified, structural optimization approach, promising key target, improved iv profile, important negative regulator, effectively inhibited pslp76, classic immunosuppressive factors, isoindoline structural motif, enhanced aqueous solubility, 26 tumor model, 49 b, 2 b, cell activity mediated, reported hpk1 inhibitor, 50 sub, 5 nm ), cell receptor signaling, cell receptor, tumor microenvironment, tme ), synergistically enhanced, isoindoline analogues
الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01571.s001Test
https://figshare.com/articles/journal_contribution/Design_Synthesis_and_Pharmacological_Evaluation_of_Isoindoline_Analogues_as_New_HPK1_Inhibitors/24610083Test -
10دورية أكاديمية
المؤلفون: Yijing Dang (3862039), Yi Lai (370972), Fengping Chen (496501), Qian Sun (53880), Chunyong Ding (1804177), Wen Zhang (7555), Zhiai Xu (1839739)
مصطلحات موضوعية: Biochemistry, Cell Biology, Physiology, Chemical Sciences not elsewhere classified, visualize disease progression, t2d blood samples, resolution viewing window, multiple chronic inflammation, local nonpolar microenvironment, good biocompatibility led, fluorescent probe tdtcd, also greatly promoted, novel activatable nanoprobe, activatable second near, t2d ), methylglyoxal, time mgo bio, ii fluorescent nanoprobe, methylglyoxal facilitated, activatable nir, water solubility, treatment effects, successfully improved, small polarity, satisfactory signal, response rate, reaction mechanism, rational packaging, quick response, potential key