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1دورية أكاديمية
المؤلفون: Grohmann, C, Magtoto, CM, Walker, JR, Chua, NK, Gabrielyan, A, Hall, M, Cobbold, SA, Mieruszynski, S, Brzozowski, M, Simpson, DS, Dong, H, Dorizzi, B, Jacobsen, A, Morrish, E, Silke, N, Murphy, JM, Heath, JK, Testa, A, Maniaci, C, Ciulli, A, Lessene, G, Silke, J, Feltham, R
العلاقة: pii: 10.1038/s41467-022-29670-1; Grohmann, C., Magtoto, C. M., Walker, J. R., Chua, N. K., Gabrielyan, A., Hall, M., Cobbold, S. A., Mieruszynski, S., Brzozowski, M., Simpson, D. S., Dong, H., Dorizzi, B., Jacobsen, A., Morrish, E., Silke, N., Murphy, J. M., Heath, J. K., Testa, A., Maniaci, C. ,. Feltham, R. (2022). Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms. NATURE COMMUNICATIONS, 13 (1), https://doi.org/10.1038/s41467-022-29670-1Test.; http://hdl.handle.net/11343/307513Test
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2دورية أكاديمية
المؤلفون: Ho, GY, Kyran, EL, Bedo, J, Wakefield, MJ, Ennis, DP, Mirza, HB, Vandenberg, CJ, Lieschke, E, Farrell, A, Hadla, A, Lim, R, Dall, G, Vince, JE, Chua, NK, Kondrashova, O, Upstill-Goddard, R, Bailey, U-M, Dowson, S, Roxburgh, P, Glasspool, RM, Bryson, G, Biankin, AV, Cooke, SL, Ratnayake, G, McNally, O, Traficante, N, DeFazio, A, Weroha, SJ, Bowtell, DD, McNeish, IA, Papenfuss, AT, Scott, CL, Barker, HE
العلاقة: NHMRC/1081178; NHMRC/1062702; NHMRC/400281; NHMRC/400413; pii: 709667; Ho, G. Y., Kyran, E. L., Bedo, J., Wakefield, M. J., Ennis, D. P., Mirza, H. B., Vandenberg, C. J., Lieschke, E., Farrell, A., Hadla, A., Lim, R., Dall, G., Vince, J. E., Chua, N. K., Kondrashova, O., Upstill-Goddard, R., Bailey, U. -M., Dowson, S., Roxburgh, P. ,. Barker, H. E. (2022). Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin. CANCER RESEARCH, 82 (23), pp.4457-4473. https://doi.org/10.1158/0008-5472.CAN-21-4012Test.; http://hdl.handle.net/11343/320081Test
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3دورية أكاديمية
المؤلفون: Ho, G-Y, Kyran, EL, Bedo, J, Wakefield, MJ, Ennis, DP, Mirza, HB, Vandenberg, CJ, Lieschke, E, Farrell, A, Hadla, A, Lim, R, Dall, G, Vince, JE, Chua, NK, Kondrashova, O, Upstill-Goddard, R, Bailey, U-M, Dowson, S, Roxburgh, P, Glasspool, RM, Bryson, G, Biankin, AV, Cooke, SL, Ratnayake, G, McNally, O, Traficante, N, DeFazio, A, Weroha, SJ, Bowtell, DD, McNeish, IA, Papenfuss, AT, Scott, CL, Barker, HE
المصدر: 4473 ; 4457
العلاقة: Cancer Research; http://hdl.handle.net/10044/1/100375Test
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4دورية أكاديمية
المؤلفون: Hughes, SA, Lin, M, Weir, A, Huang, B, Xiong, L, Chua, NK, Pang, J, Santavanond, JP, Tixeira, R, Doerflinger, M, Deng, Y, Yu, C-H, Silke, N, Conos, SA, Frank, D, Simpson, DS, Murphy, JM, Lawlor, KE, Pearson, JS, Silke, J, Pellegrini, M, Herold, M, Poon, IKH, Masters, SL, Li, M, Tang, Q, Zhang, Y, Rashidi, M, Geng, L, Vince, JE
العلاقة: Hughes, S. A., Lin, M., Weir, A., Huang, B., Xiong, L., Chua, N. K., Pang, J., Santavanond, J. P., Tixeira, R., Doerflinger, M., Deng, Y., Yu, C. -H., Silke, N., Conos, S. A., Frank, D., Simpson, D. S., Murphy, J. M., Lawlor, K. E., Pearson, J. S. ,. Vince, J. E. (2023). Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. EMBO JOURNAL, 42 (5), https://doi.org/10.15252/embj.2021110468Test.; http://hdl.handle.net/11343/339736Test
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5دورية أكاديمية
المصدر: urn:ISSN:2041-1723 ; Nat Commun, 10, 1, 888-888
مصطلحات موضوعية: Cancer, 5 Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Biosynthetic Pathways, Catalytic Domain, Cell Line, Tumor, Cholesterol, Crystallography, X-Ray, Drug Screening Assays, Antitumor, Enzyme Inhibitors, Humans, Models, Molecular, Neoplasms, Protein Conformation, Squalene Monooxygenase
وصف الملف: application/pdf
العلاقة: http://hdl.handle.net/1959.4/unsworks_69744Test; https://unsworks.unsw.edu.au/bitstreams/71dfcdca-0149-4723-be9e-39de50012fe1/downloadTest; https://doi.org/10.1038/s41467-019-08866-yTest
الإتاحة: https://doi.org/10.1038/s41467-019-08866-yTest
http://hdl.handle.net/1959.4/unsworks_69744Test
https://unsworks.unsw.edu.au/bitstreams/71dfcdca-0149-4723-be9e-39de50012fe1/downloadTest -
6دورية أكاديمية
المؤلفون: Chua, NK, Howe, V, Jatana, N, Thukral, L, Brown, AJ
المصدر: urn:ISSN:0021-9258 ; urn:ISSN:1083-351X ; Journal of Biological Chemistry, 292, 49, 19959-19973
مصطلحات موضوعية: Biotechnology, Cholesterol, Conserved Sequence, Endoplasmic Reticulum, Genetic Engineering, Humans, Hydrophobic and Hydrophilic Interactions, Intracellular Membranes, Proteasome Endopeptidase Complex, Protein Structure, Secondary, Proteolysis, Squalene Monooxygenase, cholesterol regulation, degron, endoplasmic reticulum (ER), membrane protein, protein degradation, anzsrc-for: 03 Chemical Sciences, anzsrc-for: 06 Biological Sciences, anzsrc-for: 11 Medical and Health Sciences
العلاقة: http://purl.org/au-research/grants/nhmrc/APP1060515Test; http://purl.org/au-research/grants/arc/DP170101178Test; http://hdl.handle.net/1959.4/unsworks_48460Test; https://doi.org/10.1074/jbc.M117.794230Test
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7دورية أكاديمية
المؤلفون: Howe, V, Chua, NK, Stevenson, J, Brown, AJ
المصدر: urn:ISSN:0021-9258 ; urn:ISSN:1083-351X ; Journal of Biological Chemistry, 290, 46, 27533-27544
مصطلحات موضوعية: 1.1 Normal biological development and functioning, 1 Underpinning research, Animals, CHO Cells, Cholesterol, Cricetulus, Cysteine, Endoplasmic Reticulum, Green Fluorescent Proteins, HEK293 Cells, Humans, Protein Structure, Secondary, Tertiary, Proteolysis, Recombinant Fusion Proteins, Squalene Monooxygenase, cholesterol regulation, conformational change, membrane, membrane topology, protein turnover, anzsrc-for: 03 Chemical Sciences, anzsrc-for: 06 Biological Sciences, anzsrc-for: 11 Medical and Health Sciences
العلاقة: http://purl.org/au-research/grants/nhmrc/APP1060515Test; http://hdl.handle.net/1959.4/unsworks_48461Test; https://doi.org/10.1074/jbc.M115.675181Test
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