دورية أكاديمية
Erinnerung an Professor Dr. rer.nat, Dr. med. Kázmer Jobst (1924-2016) ; In memoriam of Kázmér Jobst (1924-2016) ; Jobst Kázmér (1924-2016)
| العنوان: | Erinnerung an Professor Dr. rer.nat, Dr. med. Kázmer Jobst (1924-2016) ; In memoriam of Kázmér Jobst (1924-2016) ; Jobst Kázmér (1924-2016) |
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| المؤلفون: | Makovitzky, Josef Georg |
| المصدر: | Kaleidoscope : journal of history of science, culture and medicine; Bd. 8 Nr. 14 (2017); 263-268 ; Kaleidoscope : journal of history of science, culture and medicine; Vol. 8 No. 14 (2017); 263-268 ; Kaleidoscope : művelődés-, tudomány- és orvostörténeti folyóirat; Évf. 8 szám 14 (2017); 263-268 ; 2062-2597 |
| بيانات النشر: | LÉTRA Alapítvány és a Semmelweis Egyetem, Népegészségtani Intézet, Orvostörténeti Munkacsoportja |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | DNA-Histochemie, Feulgen-Reaktion, Polarisations-mikroskopie, Cytophotometrie, Chromatin Doppelbrechung, topo-optische Reaktion, einsträngige DNA, DNA histochemistry, Feulgen reaction, polarization microscopy, cytophotometry, chromatin birefringence, topo-optical reactions, single-stranded DNA |
| الوصف: | Prof. Dr. Kázmér (Kasimir) Jobst passed away on Nov. 5th2016 shortly before completing his 92ndyear. Prof. Jobst was a distinguished chemist, histochemist and molecular pathologist. His professional career started, continued and climaxed at The University of Pécs, Hungary. During the first period of his research he developed polarization optical analyses of isolated DNA fibrils. Then he studied the kinetics of the Feulgen reaction upon extended hydrolysis. He could show the birefringence of chromatin in cell nuclei isolated by sucrose density gradient centrifugation in Tyrode- and Hank media. With the help of so-called topo-optical reactions (histochemical reactions with polarization optical detection) he could prove the oriented structure of single-stranded DNA in formalin-fixed cell nuclei. In HeLa cell cultures he found – after treatment with non-ionic detergents – a network of filaments that encoil the cell nucleus. Later this fibrillary network was shown to be identical with the „actin-like cytoskeleton“ of bacteria.Jobst introduced a new reaction into histology, i.e. the selective staining of aldehyde-oxo groups in cells after blocking with NaBH4.From 1968 till 1992 he served as director of the clinical chemistry central laboratory of The University Pécs medical school.In 2015 he received the Gold Medal for distinguished scientific and academic achievements from the Hungarian Academy of Science. ; Prof. Dr. Kázmér (Kasimir) Jobst passed away on Nov. 5th2016 shortly before completing his 92ndyear. Prof. Jobst was a distinguished chemist, histochemist and molecular pathologist. His professional career started, continued and climaxed at The University of Pécs, Hungary. During the first period of his research he developed polarization optical analyses of isolated DNA fibrils. Then he studied the kinetics of the Feulgen reaction upon extended hydrolysis. He could show the birefringence of chromatin in cell nuclei isolated by sucrose density gradient centrifugation in Tyrode- and Hank media. With the help of ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | German Hungarian |
| العلاقة: | https://ojs.mtak.hu/index.php/kaleidoscope/article/view/522/267Test; https://ojs.mtak.hu/index.php/kaleidoscope/article/view/522/12522Test; https://ojs.mtak.hu/index.php/kaleidoscope/article/view/522Test |
| DOI: | 10.17107/kh.2017.14.263-268 |
| الإتاحة: | https://doi.org/10.17107/kh.2017.14.263-268Test https://ojs.mtak.hu/index.php/kaleidoscope/article/view/522Test |
| رقم الانضمام: | edsbas.E40ACBCE |
| قاعدة البيانات: | BASE |
| DOI: | 10.17107/kh.2017.14.263-268 |
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