نتائج البحث - "Christina Kalderén"

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دورية أكاديمية

Pharmacological OGG1 inhibition decreases murine allergic airway inflammation

المؤلفون: Lloyd Tanner, Jesper Bergwik, Ravi K. V. Bhongir, Lang Pan, Caijuan Dong, Olov Wallner, Christina Kalderén, Thomas Helleday, Istvan Boldogh, Mikael Adner, Arne Egesten

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: allergic asthma, Ogg1, macrophage polarization, NF-κB, Th2 airway inflammation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2022.999180/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/f6fed02054d74206a115008f6a48c7fbTest

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النص الكامل

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دورية أكاديمية

Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses

المصدر: Viruses, Vol 12, Iss 12, p 1423 (2020)

مصطلحات موضوعية: antivirals, virus-host interactions, pathogenic RNA viruses, HSP70, target identification, Microbiology, QR1-502

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1999-4915/12/12/1423Test; https://doaj.org/toc/1999-4915Test

الوصول الحر: https://doaj.org/article/7e99e5d7218142b29c78b60105b8de5dTest

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النص الكامل

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Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function

المؤلفون: Maurice Michel, Carlos Benítez-Buelga, Patricia A. Calvo, Bishoy M. F. Hanna, Oliver Mortusewicz, Geoffrey Masuyer, Jonathan Davies, Olov Wallner, Kumar Sanjiv, Julian J. Albers, Sergio Castañeda-Zegarra, Ann-Sofie Jemth, Torkild Visnes, Ana Sastre-Perona, Akhilesh N. Danda, Evert J. Homan, Karthick Marimuthu, Zhao Zhenjun, Celestine N. Chi, Antonio Sarno, Elisée Wiita, Catharina von Nicolai, Anna J. Komor, Varshni Rajagopal, Sarah Müller, Emily C. Hank, Marek Varga, Emma R. Scaletti, Monica Pandey, Stella Karsten, Hanne Haslene-Hox, Simon Loevenich, Petra Marttila, Azita Rasti, Kirill Mamonov, Florian Ortis, Fritz Schömberg, Olga Loseva, Josephine Stewart, Nicholas D’Arcy-Evans, Tobias Koolmeister, Martin Henriksson, Dana Michel, Ana de Ory, Lucia Acero, Oriol Calvete, Martin Scobie, Christian Hertweck, Ivan Vilotijevic, Christina Kalderén, Ana Osorio, Rosario Perona, Alexandra Stolz, Pål Stenmark, Ulrika Warpman Berglund, Miguel de Vega, Thomas Helleday

المصدر: Science. 376:1471-1476

مصطلحات موضوعية: Enzyme Activation, Oxidative Stress, Multidisciplinary, DNA Repair, Phenylalanine, Biocatalysis, Glycine, Humans, Ligands, DNA Damage, DNA Glycosylases, Substrate Specificity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3729c4fdd8e5f18775de3d2f9e81a847Test
https://doi.org/10.1126/science.abf8980Test

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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

المؤلفون: Nadilly Bonagas, Nina M. S. Gustafsson, Martin Henriksson, Petra Marttila, Robert Gustafsson, Elisée Wiita, Sanjay Borhade, Alanna C. Green, Karl S. A. Vallin, Antonio Sarno, Richard Svensson, Camilla Göktürk, Therese Pham, Ann-Sofie Jemth, Olga Loseva, Victoria Cookson, Nicole Kiweler, Lars Sandberg, Azita Rasti, Judith E. Unterlass, Martin Haraldsson, Yasmin Andersson, Emma R. Scaletti, Christoffer Bengtsson, Cynthia B. J. Paulin, Kumar Sanjiv, Eldar Abdurakhmanov, Linda Pudelko, Ben Kunz, Matthieu Desroses, Petar Iliev, Katarina Färnegårdh, Andreas Krämer, Neeraj Garg, Maurice Michel, Sara Häggblad, Malin Jarvius, Christina Kalderén, Amanda Bögedahl Jensen, Ingrid Almlöf, Stella Karsten, Si Min Zhang, Maria Häggblad, Anders Eriksson, Jianping Liu, Björn Glinghammar, Natalia Nekhotiaeva, Fredrik Klingegård, Tobias Koolmeister, Ulf Martens, Sabin Llona-Minguez, Ruth Moulson, Helena Nordström, Vendela Parrow, Leif Dahllund, Birger Sjöberg, Irene L. Vargas, Duy Duc Vo, Johan Wannberg, Stefan Knapp, Hans E. Krokan, Per I. Arvidsson, Martin Scobie, Johannes Meiser, Pål Stenmark, Ulrika Warpman Berglund, Evert J. Homan, Thomas Helleday

المصدر: Nature Cancer

مصطلحات موضوعية: Methylenetetrahydrofolate Dehydrogenase (NADP), Cancer och onkologi, Leukemia, Myeloid, Acute, Cancer Research, Oncology, Cellbiologi, Aminohydrolases, Hydrolases, Cancer and Oncology, Humans, Cell Biology, Multifunctional Enzymes, Thymidine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc803a4ce48681e11987b33fd0a94afTest
https://doi.org/10.1038/s43018-022-00331-yTest

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Front Cover: Optimization of N ‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1 (ChemMedChem 1/2023)

المصدر: ChemMedChem. 18

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c2057798a6f1ce2cc79a2bd7cf5f16fcTest
https://doi.org/10.1002/cmdc.202200681Test

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Optimization of N ‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1

المصدر: ChemMedChem

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9cd2d96f25f6a4c11257c011d10bafTest
https://doi.org/10.1002/cmdc.202200310Test

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OGG1 inhibitor TH5487 alleviates allergic airway inflammation in mice

المؤلفون: Lloyd Tanner, Jesper Bergwik, Ravi KV Bhongir, Lang Pan, Caijuan Dong, Christina Kalderén, Thomas Helleday, Istvan Boldogh, Mikael Adner, Arne Egesten

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9baf48a789486de442582f72f00fb17aTest
https://doi.org/10.1101/2022.05.17.492235Test

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Supplementary methods for 'Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress'

المؤلفون: Nadilly Bonagas, Nina Gustafsson, Martin Henriksson, Petra Marttila, Robert Gustafsson, Elisée Wiita, Sanjay Borhade, Alanna Green, Karl Vallin, Antonio Sarno, Richard Svensson, Camilla Göktürk, Therese Pham, Ann-Sofie Jemth, Olga Loseva, Victoria Cookson, Nicole Kiweler, Lars Sandberg, Azita Rasti, Judith Unterlass, Martin Haraldsson, Yasmin Andersson, Emma Scaletti, Christoffer Bengtsson, Cynthia Paulin, Kumar Sanjiv, Eldar Abdurakhmanov, Linda Pudelko, Ben Kunz, Matthieu Desroses, Petar Iliev, Katarina Färnegårdh, Andreas Krämer, Neeraj Garg, Maurice Michel, Sara Häggblad, Malin Jarvius, Christina Kalderén, Amanda Bögedahl Jensen, Ingrid Almlöf, Stella Karsten, Si Min Zhang, Maria Häggblad, Anders Eriksson, Jianping Liu, Björn Glinghammar, Natalia Nekhotiaeva, Fredrik Klingegård, Tobias Koolmeister, Ulf Martens, Sabin Llona-Minguez, Ruth Moulson, Helena Nordström, Vendela Parrow, Leif Dahllund, Birger Sjöberg, Irene Vargas, Duy Duc Vo, Johan Wannberg, Stefan Knapp, Hans Krokan, Per Arvidsson, Martin Scobie, Johannes Meiser, Pål Stenmark, Ulrika Warpman Berglund, Evert Homan, Thomas Helleday

مصطلحات موضوعية: hemic and lymphatic diseases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::032514cb5181fdda8fdfefd73848c5d0Test
https://doi.org/10.21203/rs.3.pex-1730/v1Test

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Development of a chemical probe against NUDT15

المصدر: Nature chemical biology
Nature Chemical Biology

مصطلحات موضوعية: Models, Molecular, GTP', acute lymphoblastic leukaemia, Protein Conformation, Plasma protein binding, Nudix hydrolase, Article, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, Drug Development, Escherichia coli, Structure–activity relationship, Humans, Binding site, Pyrophosphatases, Molecular Biology, Structural analog, 030304 developmental biology, 0303 health sciences, TH1760, Binding Sites, Thiopurine methyltransferase, biology, Chemistry, thiopurines, 030302 biochemistry & molecular biology, small molecule inhibitor, 6-thio-dGTP, Cell Biology, 3. Good health, Inorganic Pyrophosphatase, Biochemistry, Drug Design, biology.protein, Nucleic acid, NUDT15, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c67aef4c81a65cb8722945b628f211Test
http://europepmc.org/articles/PMC7610571Test

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Table1_Pharmacological OGG1 inhibition decreases murine allergic airway inflammation.DOCX

المؤلفون: Lloyd Tanner, Jesper Bergwik, Ravi K. V. Bhongir, Lang Pan, Caijuan Dong, Olov Wallner, Christina Kalderén, Thomas Helleday, Istvan Boldogh, Mikael Adner, Arne Egesten

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, allergic asthma, Ogg1, macrophage polarization, NF-κB, Th2 airway inflammation

العلاقة: https://figshare.com/articles/dataset/Table1_Pharmacological_OGG1_inhibition_decreases_murine_allergic_airway_inflammation_DOCX/21344802Test

الإتاحة: https://doi.org/10.3389/fphar.2022.999180.s001Test
https://figshare.com/articles/dataset/Table1_Pharmacological_OGG1_inhibition_decreases_murine_allergic_airway_inflammation_DOCX/21344802Test

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