المؤلفون: Sebastian Seufert, Roland Coras, Christian Tränkle, Darius P. Zlotos, Ingmar Blümcke, Lars Tatenhorst, Michael T. Heneka, Eric Hahnen

المصدر: PPAR Research, Vol 2008 (2008)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1687-4757Test; https://doaj.org/toc/1687-4765Test

الوصول الحر: https://doaj.org/article/2c61bcf6f78a4fd497f37037228a77f4Test

المؤلفون: Matthias Irmen, Janine Holze, Michael Kauk, Marcel Bermudez, Marco De Amici, Clelia Dallanoce, Klaus Mohr, Theresa Bödefeld, Gabriele M. König, Andreas Bock, Eva Marie Pfeil, Carsten Hoffmann, Gerhard Wolber, Carlo Matera, Ulrike Holzgrabe, Evi Kostenis, Ramona Schrage, Christian Tränkle

المصدر: ACS Pharmacol Transl Sci

مصطلحات موضوعية: Pharmacology, Coupling (electronics), Chemistry, Allosteric regulation, Biophysics, Extracellular, Pharmacology (medical), Muscarinic acetylcholine receptor M1, Receptor, Intracellular, G Protein-Coupled Receptor Signaling, G protein-coupled receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b5f203c7b3b178ef34fa4414d35cbaTest
https://doi.org/10.1021/acsptsci.0c00069Test

المؤلفون: Simon Schramm, Matthias Irmen, Christian Tränkle, Michael Decker, Timo Littmann, Hubert Gerwe, Gerhard Wolber, Luca Agnetta, Marcel Bermudez, Janine Holze

المصدر: ChemMedChem. 14:1349-1358

مصطلحات موضوعية: Pharmacology, Agonist, Allosteric modulator, 010405 organic chemistry, Stereochemistry, Chemistry, medicine.drug_class, Organic Chemistry, Allosteric regulation, Context (language use), 01 natural sciences, Biochemistry, Partial agonist, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Receptor, G protein-coupled receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::39a2e20d3265aa2902aa274db5a4008bTest
https://doi.org/10.1002/cmdc.201900283Test

المؤلفون: Janine Holze, Dina Manetti, Christian Tränkle, Klaus Mohr, Elisabetta Teodori, Maria Vittoria Martino, Cristina Bellucci, Maria Novella Romanelli, Giulio Vistoli, Jessica Welzel, Silvia Dei, Angelica Mazzolari, Marta Nesi, Ulrike Bartz, Rosanna Matucci

المصدر: European journal of pharmacology. 883

مصطلحات موضوعية: 0301 basic medicine, Carbachol, Allosteric regulation, CHO Cells, Muscarinic Antagonists, Muscarinic Agonists, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Cricetulus, Muscarinic acetylcholine receptor, medicine, Cyclic AMP, Animals, Humans, Phosphorylation, Receptor, Extracellular Signal-Regulated MAP Kinases, Pharmacology, Molecular Structure, Chemistry, Muscarinic antagonist, Receptors, Muscarinic, Molecular Docking Simulation, Kinetics, 030104 developmental biology, Docking (molecular), Guanosine 5'-O-(3-Thiotriphosphate), Biophysics, Cholinergic, Dimerization, 030217 neurology & neurosurgery, medicine.drug, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88ca14a4fbf7a1acd767dca1e4963fcTest
https://pubmed.ncbi.nlm.nih.gov/32534072Test

المؤلفون: Janine Holze, Christian Tränkle, Theresa Bödefeld, Matthias Irmen

المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology. 391:1037-1052

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Chemistry, Allosteric regulation, Muscarinic antagonist, Cooperativity, General Medicine, Methanthelinium bromide, 03 medical and health sciences, 030104 developmental biology, Muscarinic acetylcholine receptor, medicine, Biophysics, Antagonism, Receptor, Acetylcholine, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::44d577b3c1e9f36968bf3363d183b512Test
https://doi.org/10.1007/s00210-018-1525-1Test

المؤلفون: Sebastian Seufert, Christian Tränkle, Darius P. Zlotos, Ingmar Blümcke, Lars Tatenhorst, Michael T. Heneka, Eric Hahnen

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/9b/64/PPAR_Res_2008_Sep_14_2008_513943.tar.gz

وصف الملف: application/zip

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.7236Test

المؤلفون: Carlo Matera, Andreas Bock, Christoph A. Sotriffer, Brian Chirinda, Regina Messerer, Lisa Flammini, Michael Decker, Matthias Irmen, Marco De Amici, Ulrike Holzgrabe, Christian Tränkle, Elisabetta Barocelli, Sarah Wehle, Clelia Dallanoce

المصدر: MedChemComm. 8:1346-1359

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Allosteric regulation, Pharmaceutical Science, 01 natural sciences, Biochemistry, 03 medical and health sciences, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Moiety, Pharmacology, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, biology.organism_classification, In vitro, Electric eel, 0104 chemical sciences, 030104 developmental biology, Docking (molecular), Tacrine, Molecular Medicine, Linker, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ab5e32049e4149b6a64811bb9b4ea2f8Test
https://doi.org/10.1039/c7md00149eTest

المؤلفون: Esther Pohl-Rescigno, Julika Borde, Guido Neidhardt, Elisabeth Mangold, Christian Tränkle, Alfons Meindl, Harald Surowy, Norbert Arnold, Jan Hauke, Christian Sutter, Nana Weber-Lassalle, Kristina Klaschik, Gunter Rappl, Christoph Engel, Stefanie Heilmann-Heimbach, Dieter Niederacher, Sandra Schmidt, Eric Hahnen, Rita K. Schmutzler, Barbara Burwinkel, Barbara Wappenschmidt, Corinna Ernst, Konstantin Weber-Lassalle

المصدر: International journal of cancer. 144(7)

مصطلحات موضوعية: Cancer Research, business.industry, GPRC5A, Breast Neoplasms, medicine.disease, Frameshift mutation, Receptors, G-Protein-Coupled, Breast cancer, Oncology, Cancer research, medicine, Prevalence, Humans, business, Brca1 gene, Germ-Line Mutation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524572ee8c1d212bfdf0e4fefa7733c1Test
https://pubmed.ncbi.nlm.nih.gov/30474109Test

المؤلفون: Matthias, Irmen, Janine, Holze, Theresa, Bödefeld, Christian, Tränkle

المصدر: Naunyn-Schmiedeberg's archives of pharmacology. 391(10)

مصطلحات موضوعية: Radioligand Assay, Cricetulus, Methantheline, Animals, Humans, CHO Cells, Muscarinic Antagonists, N-Methylscopolamine, Binding, Competitive, Receptors, Muscarinic, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::2d6e59bcc1da206371aaac05f6700ebbTest
https://pubmed.ncbi.nlm.nih.gov/29938305Test

المؤلفون: Christoph Enzensperger, Christian Tränkle, Christian Fleck, Robert Otto, Dorothea Appenroth, Jochen Lehmann, Thomas Winckler, Friedemann Gaube, Robert Penzis

المصدر: European Journal of Medicinal Chemistry. 87:63-70

مصطلحات موضوعية: Stereochemistry, Scopolamine, Pharmacology, Receptors, N-Methyl-D-Aspartate, Neuroprotection, Structure-Activity Relationship, Alzheimer Disease, In vivo, Drug Discovery, Animals, Rats, Wistar, Maze Learning, Beta (finance), Indole test, Memory Disorders, Anti alzheimer, Chemistry, Organic Chemistry, General Medicine, Rats, Anti-Anxiety Agents, Propargyl, NMDA receptor, Female, Cognition Disorders, Antagonism, Adjuvants, Anesthesia, Carbolines

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e390437c1d94743ea2f57043d5a4ca1bTest
https://doi.org/10.1016/j.ejmech.2014.09.048Test