المؤلفون: Maas, Brian M., Lommerse, Jos, Plock, Nele, Railkar, Radha A., Cheung, S.Y. Amy, Caro, Luzelena, Chen, Jingxian, Liu, Wen, Zhang, Ying, Huang, Qinlei, Gao, Wei, Qin, Li, Meng, Jie, Witjes, Han, Schindler, Emilie, Guiastrennec, Benjamin, Bellanti, Francesco, Spellman, Daniel S., Roadcap, Brad, Kalinova, Mariya, Fok-Seang, Juin, Catchpole, Andrew P., Espeseth, Amy S., Stoch, S. Aubrey, Lai, Eseng, Vora, Kalpit A., Aliprantis, Antonios O., Sachs, Jeffrey R.

المساهمون: Merck Sharp and Dohme, Merck & Co Inc

المصدر: EBioMedicine ; volume 73, page 103651 ; ISSN 2352-3964

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology, General Medicine

الإتاحة: https://doi.org/10.1016/j.ebiom.2021.103651Test
https://api.elsevier.com/content/article/PII:S235239642100445X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S235239642100445X?httpAccept=text/plainTest

المؤلفون: Musuamba Tshinanu, Flora, Cheung, S.Y. Amy, Colin, Pieter, Davies, Elin H., Barret, Jeffrey S., Pappalardo, Francesco, Chappell, Michael J., Dogne, Jean‐Michel, Ceci, Adriana, Della Pasqua, Oscar, Rusten, Ine S.

وصف الملف: application/pdf

العلاقة: https://wrap.warwick.ac.uk/173374/1/engineering-160823-wrap--clin_pharma_and_therapeutics_-_2023_-_musuamba.pdfTest; Musuamba Tshinanu, Flora, Cheung, S.Y. Amy, Colin, Pieter, Davies, Elin H., Barret, Jeffrey S., Pappalardo, Francesco, Chappell, Michael J., Dogne, Jean‐Michel, Ceci, Adriana, Della Pasqua, Oscar and Rusten, Ine S. (2023) Moving towards a question‐centric approach for regulatory decision‐making in the context of drug assessment. Clinical Pharmacology & Therapeutics, 114 (1). pp. 41-50. doi:10.1002/cpt.2856 ISSN 1532-6535.

الإتاحة: https://doi.org/10.1002/cpt.2856Test
https://wrap.warwick.ac.uk/173374Test/
https://wrap.warwick.ac.uk/173374/1/engineering-160823-wrap--clin_pharma_and_therapeutics_-_2023_-_musuamba.pdfTest

المؤلفون: Robertson, John F.R., Coleman, Robert E., Cheung, Kwok-Leung, Evans, Abigail, Holcombe, Chris, Skene, Anthony, Rea, Daniel, Ahmed, Samreen, Jahan, Ali, Horgan, Kieran, Rauchhaus, Petra, Littleford, Roberta, Cheung, S.Y. Amy, Cullberg, Marie, de Bruin, Elza C., Koulai, Loumpiana, Lindemann, Justin P. O., Pass, Martin, Rugman, Paul, Schiavon, Gaia, Deb, Rahul, Finlay, Pauline, Foxley, Andrew, Gee, Julia M.W.

مصطلحات موضوعية: Cancer Research, Oncology

العلاقة: https://nottingham-repository.worktribe.com/output/3600603Test; Clinical Cancer Research; Volume 26; Issue 7; Pagination 1574-1585; https://nottingham-repository.worktribe.com/file/3600603/1/Capivasertib%20%28AZD5363%29,%20an%20AKT%20inhibitor,%20rapidly%20and%20effectively%20targets%20key%20AKT%20pathway%20and%20proliferation%20biomarkers%3A%20the%20STAKT%20pre-surgical%20breast%20cancer%20studyTest

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-19-3053Test
https://nottingham-repository.worktribe.com/file/3600603/1/Capivasertib%20%28AZD5363%29,%20an%20AKT%20inhibitor,%20rapidly%20and%20effectively%20targets%20key%20AKT%20pathway%20and%20proliferation%20biomarkers%3A%20the%20STAKT%20pre-surgical%20breast%20cancer%20studyTest
https://nottingham-repository.worktribe.com/output/3600603Test

المؤلفون: Fornari, Chiara, Oplustil O'Connor, Lenka, Pin, Carmen, Smith, Aaron, Yates, James W.T., Cheung, S.Y. Amy, Jodrell, Duncan I., Mettetal, Jerome T., Collins, Teresa A.

المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 8, issue 11, page 858-868 ; ISSN 2163-8306 2163-8306

الإتاحة: https://doi.org/10.1002/psp4.12459Test

المؤلفون: Musuamba, Flora T., Cheung, S.Y. Amy, Colin, Pieter, Davies, Elin H., Barret, Jeffrey S., Pappalardo, Francesco, Chappell, Michael, Dogne, Jean‐Michel, Ceci, Adriana, Della Pasqua, Oscar, Rusten, Ine S.

المصدر: Clinical Pharmacology & Therapeutics; Jul2023, Vol. 114 Issue 1, p41-50, 10p

مصطلحات موضوعية: DECISION making, MEDICAL supplies, CLINICAL pharmacology, TRAINING needs, DRUGS

المؤلفون: Kandala, Bhargava, Plock, Nele, Chawla, Akshita, Largajolli, Anna, Robey, Seth, Watson, Kenny, Thatavarti, Raj, Dubey, Sheri A., Cheung, S.Y. Amy, de Greef, Rik, Stone, Julie, Sachs, Jeffrey R.

المصدر: eBioMedicine

مصطلحات موضوعية: Articles, demo, info

العلاقة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514977Test/

الإتاحة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514977Test/

المؤلفون: Yates, James W.T., Cheung, S.Y. Amy

المصدر: European Journal of Cancer ; volume 150, page 42-52 ; ISSN 0959-8049

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1016/j.ejca.2021.03.027Test
https://api.elsevier.com/content/article/PII:S0959804921001945?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0959804921001945?httpAccept=text/plainTest

المؤلفون: Khong, Yuet Mei, Liu, Jing, Cook, Jack, Purohit, Vivek, Thompson, Karen, Mehrotra, Shailly, Cheung, S.Y. Amy, Hay, Justin L., Fletcher, Elimika Pfuma, Wang, Jian, Sachs, Hari Cheryl, Zhu, Hao, Siddiqui, Akhtar, Cunningham, Lea, Selen, Arzu

المساهمون: US Food and Drug Administration

المصدر: European Journal of Pharmaceutics and Biopharmaceutics ; volume 164, page 66-74 ; ISSN 0939-6411

مصطلحات موضوعية: Pharmaceutical Science, General Medicine, Biotechnology

الإتاحة: https://doi.org/10.1016/j.ejpb.2021.04.010Test
https://api.elsevier.com/content/article/PII:S093964112100103X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S093964112100103X?httpAccept=text/plainTest

المؤلفون: Robertson, John F.R., Coleman, Robert E., Cheung, Kwok-Leung, Evans, Abigail, Holcombe, Chris, Skene, Anthony, Rea, Daniel, Ahmed, Samreen, Jahan, Ali, Horgan, Kieran, Rauchhaus, Petra, Littleford, Roberta, Cheung, S.Y. Amy, Cullberg, Marie, de Bruin, Elza C., Koulai, Loumpiana, Lindemann, Justin P. O., Pass, Martin, Rugman, Paul, Schiavon, Gaia, Deb, Rahul, Finlay, Pauline, Foxley, Andrew, Gee, Julia M.W.

وصف الملف: application/pdf

العلاقة: https://orca.cardiff.ac.uk/id/eprint/128328/1/Capivasertib%20%28AZD5363%29,%20an%20AKT%20inhibitor,%20rapidly%20and%20effectively%20targets%20key%20AKT%20pathway%20and%20proliferation%20biomarkers-%20the%20STAKT%20pre-surgical%20breast%20cancer%20study.pdfTest; Robertson, John F.R., Coleman, Robert E., Cheung, Kwok-Leung, Evans, Abigail, Holcombe, Chris, Skene, Anthony, Rea, Daniel, Ahmed, Samreen, Jahan, Ali, Horgan, Kieran, Rauchhaus, Petra, Littleford, Roberta, Cheung, S.Y. Amy, Cullberg, Marie, de Bruin, Elza C., Koulai, Loumpiana, Lindemann, Justin P. O., Pass, Martin, Rugman, Paul, Schiavon, Gaia, Deb, Rahul, Finlay, Pauline, Foxley, Andrew and Gee, Julia M.W. https://orca.cardiff.ac.uk/view/cardiffauthors/A055751U.htmlTest orcid:0000-0001-6483-2015 orcid:0000-0001-6483-2015 2020. Proliferation and AKT activity biomarker analyses after Capivasertib (AZD5363) treatment of patients with ER+ invasive breast cancer (STAKT). Clinical Cancer Research 26 (7) , pp. 1574-1585. 10.1158/1078-0432.CCR-19-3053 https://doi.org/10.1158/1078-0432.CCR-19-3053Test file https://orca.cardiff.ac.uk/id/eprint/128328/1/Capivasertib%20%28AZD5363%29,%20an%20AKT%20inhibitor,%20rapidly%20and%20effectively%20targets%20key%20AKT%20pathway%20and%20proliferation%20biomarkers-%20the%20STAKT%20pre-surgical%20breast%20cancer%20study.pdfTest

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-19-3053Test
https://orca.cardiff.ac.uk/id/eprint/128328Test/
https://orca.cardiff.ac.uk/id/eprint/128328/1/Capivasertib%20%28AZD5363%29,%20an%20AKT%20inhibitor,%20rapidly%20and%20effectively%20targets%20key%20AKT%20pathway%20and%20proliferation%20biomarkers-%20the%20STAKT%20pre-surgical%20breast%20cancer%20study.pdfTest

المؤلفون: Banerji, Udai, Dean, Emma J., Pérez-Fidalgo, J. Alejandro, Batist, Gerald, Bedard, Philippe L., You, Benoit, Westin, Shannon N., Kabos, Peter, Garrett, Michelle D., Tall, Mathew, Ambrose, Helen, Barrett, J. Carl, Carr, T. Hedley, Cheung, S.Y. Amy, Corcoran, Claire, Cullberg, Marie, Davies, Barry R., de Bruin, Elza C., Elvin, Paul, Foxley, Andrew, Lawrence, Peter, Lindemann, Justin P.O., Maudsley, Rhiannon, Pass, Martin, Rowlands, Vicky, Rugman, Paul, Schiavon, Gaia, Yates, James, Schellens, Jan H.M.

مصطلحات موضوعية: Q Science

وصف الملف: application/pdf

العلاقة: https://kar.kent.ac.uk/63859/1/Banerji%20et%20al%202017%20R2-Merged%20manuscript%20and%20Figures-Post%20decision-accepted.pdfTest; https://kar.kent.ac.uk/63859/2/Banerji%20et%20al%202017%20R2-Supplementary%20data_.pdfTest; https://kar.kent.ac.uk/63859/3/Banerji%20et%20al%202017%20R2-Supplementary%20Table.docx.pdfTest; Banerji, Udai, Dean, Emma J., Pérez-Fidalgo, J. Alejandro, Batist, Gerald, Bedard, Philippe L., You, Benoit, Westin, Shannon N., Kabos, Peter, Garrett, Michelle D., Tall, Mathew, and others. Ambrose, Helen, Barrett, J. Carl, Carr, T. Hedley, Cheung, S.Y. Amy, Corcoran, Claire, Cullberg, Marie, Davies, Barry R., de Bruin, Elza C., Elvin, Paul, Foxley, Andrew, Lawrence, Peter, Lindemann, Justin P.O., Maudsley, Rhiannon, Pass, Martin, Rowlands, Vicky, Rugman, Paul, Schiavon, Gaia, Yates, James, and Schellens, Jan H.M. (hide) (2018) A Phase 1 open-label study to identify a dosing regimen of the pan-AKT inhibitor AZD5363 for evaluation in solid tumors and in PIK3CA-mutated breast and gynecologic cancers. Clinical Cancer Research, 24 (9). pp. 2050-2059. ISSN 1078-0432. E-ISSN 1557-3265. (doi:10.1158/1078-0432.CCR-17-2260 ) (KAR id:63859 )

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-17-2260Test
https://kar.kent.ac.uk/63859Test/
https://kar.kent.ac.uk/63859/1/Banerji%20et%20al%202017%20R2-Merged%20manuscript%20and%20Figures-Post%20decision-accepted.pdfTest
https://kar.kent.ac.uk/63859/2/Banerji%20et%20al%202017%20R2-Supplementary%20data_.pdfTest
https://kar.kent.ac.uk/63859/3/Banerji%20et%20al%202017%20R2-Supplementary%20Table.docx.pdfTest