التفاصيل البيبلوغرافية
| العنوان: |
Accelerated Mimetic Oxidase Activity of Polydopamine-Dressed PdCu Nanozyme for the Detection of Ascorbic Acid Related Bioenzymes |
| المؤلفون: |
Chenghui Zhang (6008435), Wendong Liu (507488), Zhe Li (219258), Bingsong Yan (11961106), Jiatong Lin (7863038), Chuanxia Chen (1430191), Libing Zhang (1481890), Yizhong Lu (1761193) |
| سنة النشر: |
2022 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biophysics, Cell Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, spontaneous accumulating nature, making full use, generating alkaline phosphatase, 5 ′- tetramethylbenzidine, undesirable catalytic activity, 3 ′, dressed pdcu alloy, gel formation time, enhanced substrate affinity, combining surface modification, 4 , dressed pdcu nanozyme, surface modification, using 3, like activity, enhanced oxidase, chromogenic substrate, pdcu samples, successfully prepared, related bioenzymes, reduction method, pot nabh, ox ), nanosized noble |
| الوقت: |
5 |
| الوصف: |
The spontaneous accumulating nature and undesirable catalytic activity of nanosized noble-metal nanoparticle-based nanozymes significantly limit their applications in the bioanalytical field. Herein, by combining surface modification and nonprecious metal doping strategies, polydopamine-dressed PdCu alloy (PDA-PdCu) nanozymes with nanochain networks are successfully prepared through a facile one-pot NaBH 4 reduction method. It is found that dopamine can shorten the gel formation time and Cu is indispensable for the formation of jelly-like PDA-PdCu samples with chain-like structures. Notably, benefiting from the improved Pd(0)/Pd(II) ratio, the enhanced substrate affinity, and the increased active surface area, the synthesized PDA-PdCu samples exhibit considerably enhanced oxidase mimetic activity compared to PDA-Pd and PdCu nanozymes. By making full use of the enhanced oxidase-like activity of PDA-PdCu and using 3,3′,5,5′-tetramethylbenzidine as a chromogenic substrate, a sensitive and straightforward colorimetric biosensing strategy for ascorbic acid (AA)-related bioenzyme activity, including the AA-generating alkaline phosphatase (ALP) and α-glucosidase (α-Glu) as well as the AA-consuming ascorbic acid oxidase (AA-ox), is elaborately developed. This work not only elucidates that the performance of the nanozyme can be modulated simultaneously by composition and surface modification but also provides a new versatile colorimetric sensing platform for AA-related bioenzymes. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/journal_contribution/Accelerated_Mimetic_Oxidase_Activity_of_Polydopamine-Dressed_PdCu_Nanozyme_for_the_Detection_of_Ascorbic_Acid_Related_Bioenzymes/18627283Test |
| DOI: |
10.1021/acssuschemeng.1c07568.s001 |
| الإتاحة: |
https://doi.org/10.1021/acssuschemeng.1c07568.s001Test |
| حقوق: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.FCE54B39 |
| قاعدة البيانات: |
BASE |
