المؤلفون: Rosa Camarillo, Pablo Huertas, Sonia Jimeno

المساهمون: [Camarillo,R: Jimeno,S, Huertas,P] Departamento de Genética, Universidad de Sevilla, Sevilla, Spain. [Camarillo,R: Jimeno,S, Huertas,P] Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Sevilla, Spain., This work was funded by the R + D + I grant PID 2019-104195G from the Spanish Ministry of Science and Innovation-Agencia Estatal de Investigación/10.13039/501100011033. RC-D is funded by an FPI fellowships from the Spanish Ministry of Science. CABIMER is supported by the regional government of Andalucia (Junta de Andalucía)., Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Junta de Andalucía, Universidad de Sevilla. Departamento de Genética, Agencia Estatal de Investigación. España 10.13039/501100011033

المصدر: Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla

مصطلحات موضوعية: DNA end resection, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Molecular Conformation::Nucleic Acid Conformation::G-Quadruplexes [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Structures::Nucleic Acid Conformation::G-Quadruplexes [Medical Subject Headings], ADN, QH426-470, G-quadruplex, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids [Medical Subject Headings], Resection, chemistry.chemical_compound, Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Learning::Cues [Medical Subject Headings], Recombinación homóloga, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Homologous Recombination [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA [Medical Subject Headings], Genetics, Genetics (clinical), Double strand, Phenomena and Processes::Biological Phenomena [Medical Subject Headings], R-loops, G-cuádruplex, Double Strand Break Repair, Cell biology, ARN, chemistry, DNA double strand break repair, Homologous recombination (HR), Perspective, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Nucleic Acid Conformation::DNA, B-Form [Medical Subject Headings], Nucleic acid, Molecular Medicine, Homologous recombination, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], DNA, Estructuras R-loop

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd244bea64742c5ac9080fe66df384cTest
https://hdl.handle.net/10668/4085Test

المؤلفون: Josué Martínez-de la Puente, Rafael Gutiérrez-López, Alazne Díez-Fernández, Ramón C. Soriguer, Isabel Moreno-Indias, Jordi Figuerola

المساهمون: [Martínez-de la Puente,J, Gutiérrez-López,R, Díez-Fernández,A, Soriguer,RC, Figuerola,J] Estación Biológica de Doñana (EBD-CSIC), Seville, Spain. [Martínez-de la Puente,J, Figuerola,J] Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. [Moreno-Indias,I] Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Instituto de Investigación Biomédica de Málaga (IBIMA), University of Malaga, Málaga, Spain. [Moreno-Indias,I] Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain., This study was supported by a grant from the Spanish Society of Ethology and Evolutionary Ecology to JM-P and by the projects CGL2015-65055-P and PGC2018-095704-B-I00 from the Spanish Ministry of Economy and Competition and from the European Regional Development Fund (FEDER) to JF. IM-I was supported by the 'MS type I' program (CP16/00163) from the ISCIII cofounded by FEDER. AD-F was supported by Severo-Ochoa grant from the Spanish Ministry of Economy and Competitiveness (SVP-2014-068571).

المصدر: Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Frontiers in Microbiology, Vol 11 (2021)
Digital.CSIC. Repositorio Institucional del CSIC

مصطلحات موضوعية: Vector-borne pathogens, Chemicals and Drugs::Carbohydrates::Glycosides::Aminoglycosides::Streptomycin [Medical Subject Headings], Antibiotics, lcsh:QR1-502, Plasmodium, lcsh:Microbiology, 0302 clinical medicine, Culex pipiens, Organisms::Eukaryota::Animals [Medical Subject Headings], Parasite hosting, Parasitología, 0303 health sciences, Virulence, biology, Transmission (medicine), Microbiota, Culex, Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Parasitology [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Control Groups [Medical Subject Headings], Microbiology (medical), Enfermedades transmitidas por vectores, Chemicals and Drugs::Carbohydrates::Glycosides::Aminoglycosides::Gentamicins [Medical Subject Headings], medicine.drug_class, 030231 tropical medicine, Organisms::Eukaryota::Alveolata::Apicomplexa::Haemosporida::Plasmodium [Medical Subject Headings], Microbiology, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Birds::Passeriformes::Songbirds::Sparrows [Medical Subject Headings], 03 medical and health sciences, parasitic diseases, medicine, Microbiome, Ecology-diseases, 030304 developmental biology, Virulencia, fungi, Parasite transmission, Anatomy::Hemic and Immune Systems::Immune System [Medical Subject Headings], Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Penicillins [Medical Subject Headings], biology.organism_classification, medicine.disease, Malaria, Mosquitos vectores, Diseases::Parasitic Diseases::Protozoan Infections::Malaria::Malaria, Avian [Medical Subject Headings], Anatomy::Fluids and Secretions::Bodily Secretions::Saliva [Medical Subject Headings], Vector (epidemiology), Organisms::Eukaryota::Animals::Invertebrates::Arthropods::Insects::Diptera::Culicidae::Culex [Medical Subject Headings], Disciplines and Occupations::Health Occupations::Medicine::Public Health::Epidemiology [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], Parásitos

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5eaf411e20399177c08fc75d534b105Test

المؤلفون: Pedro Ortega, José Antonio Mérida-Cerro, Ana G Rondón, Belén Gómez-González, Andrés Aguilera

المساهمون: Universidad de Sevilla. Departamento de Genética, European Commission, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Junta de Andalucía, Ministerio de Educación, Cultura y Deporte (España), [Ortega,P, Mérida-Cerro,JA, Rondón,AG, Gómez-González,B, Aguilera,A] Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain., H2020 European Research Council ERC2014 AdG669898 TARLOOP Andrés Aguilera. Ministerio de Economía y Competitividad BFU2016-75058-P Andrés Aguilera. Ministerio de Ciencia, Innovación y Universidades PDI2019-104270GB-I00 Andrés Aguilera. Junta de Andalucía P12-BIO-1238 Andrés Aguilera. European Regional Development Fund Andrés Aguilera. Ministerio de Educación, Cultura y Deporte PhD FPU fellowship Pedro Ortega. Junta de Andalucía PhD fellowship Jose Antonio Mérida-Cerro. Junta de Andalucía P18-FR-566 Andrés Aguilera.

المصدر: idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
eLife, Vol 10 (2021)
eLife

مصطلحات موضوعية: Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair [Medical Subject Headings], DNA Repair, ADN, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Fungal Proteins::Saccharomyces cerevisiae Proteins [Medical Subject Headings], S. cerevisiae, Hybrids, homologous recombination, DSB repair, Quimera, chemistry.chemical_compound, 0302 clinical medicine, Plasmid, DNA-RNA hybrids, Transcription (biology), Recombinación homóloga, Gene Expression Regulation, Fungal, Gene expression, Roturas del ADN de doble cadena, DNA Breaks, Double-Stranded, ssDNA breaks, Biology (General), Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Nucleic Acid Hybridization [Medical Subject Headings], Organisms::Eukaryota::Fungi::Ascomycota::Saccharomycetales::Saccharomyces::Saccharomyces cerevisiae [Medical Subject Headings], 0303 health sciences, biology, General Neuroscience, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Replication [Medical Subject Headings], Nucleic Acid Hybridization, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::Recombinational DNA Repair [Medical Subject Headings], General Medicine, Chromosomes and Gene Expression, Cell biology, ARN, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Alcohol Oxidoreductases::NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases::3-Isopropylmalate Dehydrogenase [Medical Subject Headings], Medicine, transcription, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Fungal [Medical Subject Headings], Recombination, Research Article, DNA Replication, chromosomes, replication, Saccharomyces cerevisiae Proteins, Double-strand breaks, QH301-705.5, Science, Saccharomyces cerevisiae, General Biochemistry, Genetics and Molecular Biology, 3-Isopropylmalate Dehydrogenase, 03 medical and health sciences, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA [Medical Subject Headings], 030304 developmental biology, General Immunology and Microbiology, DNA replication, Recombinational DNA Repair, DNA, biology.organism_classification, chemistry, gene expression, RNA, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], Homologous recombination, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddf2188d1b8a2089ef8bb5e1005ce92Test

المؤلفون: Gauthier, Benoit R., Comaills, Valentine

المساهمون: Asociación Española Contra el Cáncer, Fundación Vencer el Cancer, Junta de Andalucía, Instituto de Salud Carlos III, European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Juvenile Diabetes Research Foundation, [Gauthier,BR, Comaills,V] Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain. [Gauthier,BR] Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., Authors were/are funded by grants from the Spanish association against the Cancer AECC (Aecc investigator to V.C. INVES20033COMA) and from the Fundación Vencer el Cáncer (to B.R.G. and V.C). B.R.G. was/is funded by grants from Consejería de Salud, Fundación Pública AndaluzaProgreso y Salud, Junta de Andalucía (PI-0727-2010, December 2010 to B.R.G. and PI-0001-2020, December 2020 to B.R.G.), Consejería de Economía, Innovación y Ciencia, Junta de Andalucía (P10-CTS-6359 to B.R.G.), Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, cofunded by Fondos FEDER (PI10/00871, January 2011and PI13/00593, January 2014 to B.R.G.), Ministerio de Economía y Competitividad, Plan Nacional(BFU2017-83588-P, January 2018 to B.R.G.), JuvenileDiabetes Research Foundation JDRF (17-2013-372, August 2013 and 2-SRA-2019-837-S-B, August 2019 to B.R.G.).

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Anatomy::Cells::Cellular Structures::Cell Membrane::Cell Membrane Structures::Nuclear Envelope [Medical Subject Headings], Inflammation, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Chromosome Aberrations::Chromosomal Instability [Medical Subject Headings], Inflamación, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage [Medical Subject Headings], Lipodystrophy, Nuclear envelope disruption, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Genomic Instability [Medical Subject Headings], Inestabilidad cromosómica, cGAS/STING, Neoplasias, Nuclear envelope, Chromosomal instability, Neuropathy, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Organisms::Eukaryota::Animals [Medical Subject Headings], Phenomena and Processes::Immune System Phenomena::Immunity::Immunity, Innate [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation [Medical Subject Headings], Envelopathy, Cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0638ce1fa1d4f95c898e472ae10984e5Test
http://hdl.handle.net/10261/259669Test

المؤلفون: Valor, Luis M., Hervás-Corpión, Irati

المساهمون: [Valor,LM, Hervás-Corpión,I] Unidad de Investigación, Hospital Universitario Puerta del Mar, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Cádiz, Spain., LV is supported by the Plan Propio INiBICA (Grant L19-07IN-CO07) and by the Programa Estatal de Generación de Conocimiento y Fortalecimiento del Sistema Español de I+D+i, financed by the Instituto de Salud Carlos III and Fondo Europeo de Desarrollo Regional 2014-2020 (Grants CP15/00180 and PI16/00722). LV is the recipient of a Miguel Servet I contract (CP15/00180) financed by the Instituto de Salud Carlos III and Fondo Social Europeo 2014-2020, Programa Estatal de Promoción del Talento y su empleabilidad en I+D+i.

مصطلحات موضوعية: Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Nerve Tissue::Neuroectodermal Tumors::Neoplasms, Neuroepithelial::Glioma::Astrocytoma::Glioblastoma [Medical Subject Headings], HDACi, ADN, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic [Medical Subject Headings], Acetylation, Anatomy::Cells::Stem Cells::Neoplastic Stem Cells [Medical Subject Headings], DNA, H3.3, Phenomena and Processes::Metabolic Phenomena::Metabolism::Acylation::Acetylation [Medical Subject Headings], Methylation, Polycomb, Acetilación, Histone, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation [Medical Subject Headings], Histonas, Metilación, Glioblastoma, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], Anatomy::Cells::Stem Cells::Neural Stem Cells [Medical Subject Headings]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______2636::369b12c563c81c18e63e7f6e0afe7f6aTest
https://hdl.handle.net/10668/3546Test

المؤلفون: Sanchez-Martin, Victoria, Lopez-Pujante, Carmen, Soriano-Rodriguez, Miguel, Garcia-Salcedo, Jose A.

المساهمون: [Sanchez-Martin,V, Lopez-Pujante,C, Soriano-Rodriguez,M, Garcia-Salcedo,JA] GENYO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, Granada, Spain. [Sanchez-Martin,V, Garcia-Salcedo,JA] Microbiology Unit, University Hospital Virgen de las Nieves, Biosanitary Research Institute IBS, Granada, Spain. [Sanchez-Martin,V] Department of Biochemistry, Molecular Biology III and Immunology, University of Granada, Granada, Spain. [Soriano-Rodriguez,M] Centre for Intensive Mediterranean Agrosystems and Agri-food Biotechnology (CIAMBITAL), University of Almeria, Almeria, Spain., This study was supported by 3TR, IMI2 (H2020-JTI538 IMI2-2018) and by Instituto de Salud Carlos III under the frame of EuroNanoMed III (AC18/00008) to J.A.G.S. The Government of Spain granted with PhD fellowship FPU16/05822 to V.S.M.

مصطلحات موضوعية: Citosina, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Purines::Purinones::Hypoxanthines::Guanine [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Structures::Nucleic Acid Conformation::G-Quadruplexes [Medical Subject Headings], ADN, Guanina, DNA G-quadruplex, Oncogenes, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Molecular Targeted Therapy [Medical Subject Headings], Diseases::Neoplasms [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus::Cell Nucleus Structures::Intranuclear Space::Chromosomes::Chromosome Structures::Telomere [Medical Subject Headings], Neoplasias, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyrimidines::Pyrimidinones::Cytosine [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins [Medical Subject Headings], RNA G-quadruplex, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Ácidos nucleicos, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Neoplasm::Oncogenes [Medical Subject Headings], heterocyclic compounds, i-Motif, G-Cuádruplex, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], Telómero, Cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______2636::e18f43c3ef61991d520b296ac7d5dbafTest
https://hdl.handle.net/10668/3653Test

المؤلفون: Magán-Fernández, Antonio, Rasheed Al-Bakri, Sarmad Muayad, O'Valle, Francisco, Benavides-Reyes, Cristina, Abadía-Molina, Francisco, Mesa, Francisco

المساهمون: [Magán-Fernández,A, Rasheed Al-Bakri, SM, Mesa,F] Periodontology Department, School of Dentistry, University of Granada, 18071 Granada, Spain. [O'Valle,F] Pathology Department, School of Medicine (IBIMER, CIBM), University of Granada, Granada, Spain. [O'Valle,F] Biosanitary Research Institute (IBS-GRANADA), University of Granada, Granada, Spain. [Benavides-Reyes,C] Department of Operative Dentistry, School of Dentistry, University of Granada, Granada, Spain. [Abadía-Molina,F] Department of Cell Biology, University of Granada, Granada, Spain. [Abadía-Molina,F] INYTA, Institute of Nutrition and Food Technology 'José Mataix', University of Granada, Armilla, Granada, Spain.

مصطلحات موضوعية: Innate immunity, Trampas extracelulares, Neutrófilos, Diseases::Stomatognathic Diseases::Mouth Diseases::Periodontal Diseases::Periodontitis [Medical Subject Headings], Chemicals and Drugs::Inorganic Chemicals::Free Radicals::Reactive Oxygen Species [Medical Subject Headings], Anatomy::Cells [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nuclear Proteins::Histones [Medical Subject Headings], Neutrophil extracellular traps, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Organisms::Bacteria::Bacteroidetes::Bacteroidaceae::Porphyromonas::Porphyromonas gingivalis [Medical Subject Headings], Phenomena and Processes::Immune System Phenomena::Immunity::Immunity, Innate [Medical Subject Headings], Neutrophil functions, Anatomy::Cells::Blood Cells::Leukocytes::Granulocytes::Neutrophils [Medical Subject Headings], Periodontitis, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], Inmunidad innata, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation [Medical Subject Headings], Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis [Medical Subject Headings]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______2636::816a40fb283fcdbdb0cf2bf317d476e1Test
https://hdl.handle.net/10668/3791Test

المؤلفون: Gaëlle Legube, Sérgio F. de Almeida, Pablo Huertas, Alexandra C Vítor

المساهمون: Laboratoire de Biologie Cellulaire et Moléculaire du Contrôle de la Prolifération (LBCMCP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Repositório da Universidade de Lisboa, Fundação para a Ciência e a Tecnologia (Portugal), European Commission, Programa Operacional do Potencial Humano (Portugal), European Research Council, Agence Nationale de la Recherche (France), Ligue Nationale contre le Cancer (France), Institut National du Cancer (France), Universidad de Sevilla. Departamento de Genética, [Vítor,AC, de Almeida,SF] Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal. [Huertas,P] Department of Genetics, University of Seville, Seville, Spain. [Huertas,P] Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain. [Legube,G] LBCMCP, Centre de Biologie Integrative (CBI), CNRS, Université de Toulouse, Toulouse, France., Work in the SA lab was funded by PTDC/BIM-ONC/0016/2014 and PTDC/BIA-MOL/30438/2017 from Fundação para a Ciência e a Tecnologia (FCT), Portugal, by LISBOA-01-0145-FEDER-007391, project co-funded by FEDER through POR Lisboa, Portugal 2020–Programa Operacional Regional de Lisboa, and FCT, and by the IMM-Laço Fund. The GL laboratory was funded by grants from the European Research Council (ERC-2014-CoG 647344), Agence Nationale pour la Recherche (ANR-18-CE12-0015-02), the Institut National contre le Cancer (INCA), and the Ligue Nationale contre le Cancer (LNCC).

المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Frontiers Media, 2020, 7, ⟨10.3389/fmolb.2020.00024⟩
Frontiers in Molecular Biosciences, Vol 7 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla

مصطلحات موضوعية: 0301 basic medicine, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair [Medical Subject Headings], Non-homologous DNA end joining, Cell cycle checkpoint, DNA damage, DNA repair, [SDV]Life Sciences [q-bio], ComputingMilieux_LEGALASPECTSOFCOMPUTING, Review, Computational biology, Biology, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints [Medical Subject Headings], Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Cromatina, homologous recombination (HR), 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded [Medical Subject Headings], Recombinación homóloga, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Homologous Recombination [Medical Subject Headings], Roturas del ADN de doble cadena, Reparación del ADN por unión de extremidades, Molecular Biosciences, Molecular Biology, lcsh:QH301-705.5, ComputingMilieux_MISCELLANEOUS, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Chromosome Structures::Chromatin [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::DNA End-Joining Repair [Medical Subject Headings], Double Strand Break Repair, Chromatin, 3. Good health, 030104 developmental biology, Daño del ADN, chemistry, lcsh:Biology (General), Homologous recombination (HR), 030220 oncology & carcinogenesis, Reparación del ADN, chromatin, Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], DNA, non-homologous DNA end joining

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e0e0736246065f19724974f8131932Test
https://hal.archives-ouvertes.fr/hal-03011382Test

المؤلفون: Serrano-Benítez, Almudena, Cortés-Ledesma, Felipe, Ruiz, Jose F.

المساهمون: [Serrano-Benítez,A, Cortés-Ledesma,F, Ruiz,JF] Andalusian Center of Molecular Biology and Regenerative Medicine (CABIMER-CSIC-University of Seville-Pablo de Olavide University), Seville, Spain. [Cortés-Ledesma,F] Topology and DNA breaks Group, Spanish National Cancer Research Center, Madrid, Spain. [Ruiz,JF] Department of Plant Biochemistry and Molecular Biology, University of Seville, Seville, Spain., Work in the FC-L laboratory was funded with grants from the Spanish and Andalusian Government (SAF2017-89619-R, CVI-7948, European Regional Development Fund), and the European Research Council (ERC-CoG-2014-647359), and with an individual fellowship for AS-B (Beca Predoctoral AEFAT, Asociación Española Familia Ataxia Telangiectasia). CABIMER was supported by the Andalusian Government.

مصطلحات موضوعية: Non-homologous DNA end joining, DNA-PK catalytic subunit, ADN, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence [Medical Subject Headings], DNA double strand break (DSB), Genome instability, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::DNA-Activated Protein Kinase [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Ataxia Telangiectasia Mutated Proteins [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::DNA End-Joining Repair [Medical Subject Headings], Proteínas de la ataxia telangiectasia mutada, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded [Medical Subject Headings], ATM, Roturas del ADN de doble cadena, Reparación del ADN por unión de extremidades, Proteína quinasa activada por ADN, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______2636::31cb904f46bc6e1baa6a359817b09fb3Test
https://hdl.handle.net/10668/3746Test

المؤلفون: Cecilio López-Galíndez, Rebeca S. de Pablo-Bernal, Carmen Rodríguez, Isabel Olivares, Ezequiel Ruiz-Mateos, Maria Pernas, Mar Vera, Alberto Merino-Mansilla, Ramon Lorenzo-Redondo, Victor Sanchez-Merino, Maria Cristina O. Salgado, Cristina Gálvez, Concepción Casado, Javier Martinez-Picado, Laura Tarancon-Diez, Jorge del Romero

المساهمون: Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), Red Española de Investigación en SIDA, European Commission, Junta de Andalucía, Grifols, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Red de Investigación Cooperativa en Investigación en Sida (España), Regional Government of Andalusia (España), [Casado,C, Pernas,M, Olivares,I, Lopez-Galindez,C] Virología Molecular, Laboratorio de Referencia e Investigación en Retrovirus, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain. [Galvez,C, Salgado,M, Martinez-Picado,J] AIDS Research Institute IrsiCaixa, Badalona, Spain. [Galvez,C] Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain. [Tarancon-Diez,L, De Pablo-Bernal,R, Ruiz-Mateos,E] Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), Virgen del Rocío University Hospital, CSIC, University of Seville, Seville, Spain. [Rodriguez,C, Vera,M, Del Romero,J] Centro Sanitario Sandoval, Hospital Clínico San Carlos. IdISSC, Madrid, Spain. [Sanchez-Merino,V, Merino-Mansilla,A] AIDS Immunopathology Unit. Laboratorio de Referencia e Investigación en Retrovirus. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain. [Lorenzo-Redondo,R] Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. [Martinez-Picado,J] University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain. [Martinez-Picado,J] Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain., Work in Centro Nacional de Microbiologia (ISCIII) was supported by grants SAF (2016–77894-R) from Ministerio de Economia y Competitividad (MINECO) (Spain) and Fondo de Investigación Sanitaria(FIS)-Instituto de Salud CarlosIII, grant FIS (PI 13/02269, ISCIII) and in part by the RIS-RETIC grants RD12/0017/0028 and RD16CIII/0002/0005 funded by the ISCIII-FEDER. MP has a contract of RIS-RETICRD16CIII/0002/0005. Tis work was supported by grants from the MINECO, FIS-Instituto de Salud CarlosIII, Fondos Europeos para el Desarrollo Regional, FEDER, grant numbers PI16/00684, PI19/01127, CPII014/00025 to ER-M. and FI14/00431 to LT-D., the Gilead Fellowship Program (grant numbers GLD17/00299), the Red de Investigación en Sida (grant number RD16/0025/0020). ER-M. is supported by Consejería de Salud y BienestarSocial of Junta de Andalucía through the Nicolás Monardes Program (C-0032/17). Research in VS-M group was supported by Fondo de Investigación Sanitaria (FIS)-Instituto de Salud CarlosIII, grant FIS (PI 17CIII/00049). Grifols partially supported work in the AIDS Research Institute IrsiCaixa.

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol

مصطلحات موضوعية: 0301 basic medicine, Male, ADN, Remission, Spontaneous, Diseases, HIV Infections, Pathogenesis, Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::CD4-Positive T-Lymphocytes [Medical Subject Headings], Virus Replication, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Microbial::Genes, Viral::Genes, env [Medical Subject Headings], Viral load, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Biological [Medical Subject Headings], Multidisciplinary, Molecular medicine, Middle Aged, Viral Load, Virus, Viral evolution, Viruses, Spontaneous cure, Disease Progression, Medicine, Diseases::Immune System Diseases::Immunologic Deficiency Syndromes::HIV Infections [Medical Subject Headings], Female, medicine.symptom, VIH-1, Evolution, Science, 030106 microbiology, Check Tags::Male [Medical Subject Headings], Inflammation, Models, Biological, Article, HIV Long-Term Survivors, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Microbiological Techniques::Viral Load [Medical Subject Headings], 03 medical and health sciences, Immune system, Elite controllers, HIV, Progresión de la enfermedad, medicine, Humans, Allele, Disease progression, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression [Medical Subject Headings], Organisms::Viruses::RNA Viruses::Retroviridae::Lentivirus::Lentiviruses, Primate::HIV::HIV-1 [Medical Subject Headings], Host Microbial Interactions, business.industry, Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings], DNA, Phenomena and Processes::Immune System Phenomena::Immunity [Medical Subject Headings], Persons::Persons::Patients::Survivors::HIV Long-Term Survivors [Medical Subject Headings], Carga viral, Phenomena and Processes::Microbiological Phenomena::Microbiological Processes::Virus Physiological Processes::Virus Replication [Medical Subject Headings], 030104 developmental biology, Check Tags::Female [Medical Subject Headings], Viral replication, Immunology, HIV-1, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression::Remission, Spontaneous [Medical Subject Headings], VIH no-progresivos, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], business, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b214399cf8eb1e7b6c313351383dbee9Test
http://hdl.handle.net/10261/228602Test