دورية أكاديمية

COVID-19 Vaccination and New Onset Glomerular Disease : Results from the IRocGN2 International Registry

التفاصيل البيبلوغرافية
العنوان: COVID-19 Vaccination and New Onset Glomerular Disease : Results from the IRocGN2 International Registry
المؤلفون: Waldman, Meryl, Sinaii, Ninet, Lerma, Edgar V., Kurien, Anila Abraham, Jhaveri, Kenar D., Uppal, Nupur N., Wanchoo, Rimda, Avasare, Rupali, Zuckerman, Jonathan E., Liew, Adrian, Gallan, Alexander J., El-Meanawy, Ashraf, Yagil, Yoram, Lebedev, Larissa, Baskaran, Krishoban, Vilayur, Eswari, Cohen, Adrienne, Weerasinghe, Nethmi, Petrakis, Ioannis, Stylianou, Kostas, Gakiopoulou, Hariklia, Hamilton, Alexander J., Edney, Naomi, Millner, Rachel, Marinaki, Smaragdi, Rein, Joshua L., Killen, John Paul, Chagolla, Jose ManuelRodriguez, Bassil, Claude, del Valle, Ramon Lopez, Evans, Jordan, Urisman, Anatoly, Zawaideh, Mona, Baxi, Pravir V., Rodby, Roger, Vankalakunti, Mahesha, Vilet, Juan Mejia M., Andrade, Silvia Ramirez E., Homan, Mal P., Jimenez, Enzo Vasquez, Perinpanayagam, Natasha, Velez, Juan Carlos Q., Mohamed, Muner M. B., Mohammed, Khalid M. G., Sekar, Arjun, Ollila, Laura, Aron, Abraham W., Arteaga, Kevin Javier Arellano, Islam, Mahmud, Berrio, Esperanza Moral, Maoujoud, Omar, Morales, Rebecca Ruf, Seipp, Regan, Schulze, Carl E., Yenchek, Robert H., Vancea, Irina, Muneeb, Muhammad, Howard, Lilian, Caza, Tiffany N.
المساهمون: HUS Heart and Lung Center
بيانات النشر: American Society of Nephrology
سنة النشر: 2024
المجموعة: Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto
مصطلحات موضوعية: Covid-19, Glomerular and Tubulointerstitial Diseases, IRocGN2, Registries, Covid-19 vaccine, Glomerular, Kidney, Nephrotic, General medicine, internal medicine and other clinical medicine
الوصف: Background Patients with de novo glomerular disease (GD) with various renal histologies have been reported after vaccination against SARS-CoV-2. Causality has not been established, and the long-term outcomes are not known. To better characterize the GDs and clinical courses/outcomes, we created the International Registry of COVID-19 vaccination and Glomerulonephritis to study in aggregate patients with de novo GN suspected after COVID-19 vaccine exposure.Methods A REDCap survey was used for anonymized data collection. Detailed information on vaccination type and timing and GD histology were recorded in the registry. We collected serial information on laboratory values (before and after vaccination and during follow-up), treatments, and kidney-related outcomes.Results Ninety-eight patients with GD were entered into the registry over 11 months from 44 centers throughout the world. Median follow-up was 89 days after diagnosis. IgA nephropathy (IgAN) and minimal change disease (MCD) were the most common kidney diseases reported. Recovery of kidney function and remission of proteinuria were more likely in IgAN and MCD at 4-6 months than with pauci-immune GN/vasculitis and membranous nephropathy.Conclusions The development of GD after vaccination against SARS-CoV-2 may be a very rare adverse event. Temporal association is present for IgAN and MCD, but causality is not firmly established. Kidney outcomes for IgAN and MCD are favorable. No changes in vaccination risk-benefit assessment are recommended based on these findings. ; Peer reviewed
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
ردمك: 978-0-00-970062-0
0-00-970062-5
العلاقة: Waldman , M , Sinaii , N , Lerma , E V , Kurien , A A , Jhaveri , K D , Uppal , N N , Wanchoo , R , Avasare , R , Zuckerman , J E , Liew , A , Gallan , A J , El-Meanawy , A , Yagil , Y , Lebedev , L , Baskaran , K , Vilayur , E , Cohen , A , Weerasinghe , N , Petrakis , I , Stylianou , K , Gakiopoulou , H , Hamilton , A J , Edney , N , Millner , R , Marinaki , S , Rein , J L , Killen , J P , Chagolla , J M , Bassil , C , del Valle , R L , Evans , J , Urisman , A , Zawaideh , M , Baxi , P V , Rodby , R , Vankalakunti , M , Vilet , J M M , Andrade , S R E , Homan , M P , Jimenez , E V , Perinpanayagam , N , Velez , J C Q , Mohamed , M M B , Mohammed , K M G , Sekar , A , Ollila , L , Aron , A W , Arteaga , K J A , Islam , M , Berrio , E M , Maoujoud , O , Morales , R R , Seipp , R , Schulze , C E , Yenchek , R H , Vancea , I , Muneeb , M , Howard , L & Caza , T N 2023 , ' COVID-19 Vaccination and New Onset Glomerular Disease : Results from the IRocGN2 International Registry ' , Kidney360 , vol. 4 , no. 3 , pp. 349-362 . https://doi.org/10.34067/KID.0006832022Test; http://hdl.handle.net/10138/572155Test; a69fcb51-0139-4ee7-871d-06489d7fbc9b; 000970062500013
الإتاحة: http://hdl.handle.net/10138/572155Test
حقوق: cc_by_nc_nd ; info:eu-repo/semantics/openAccess ; openAccess
رقم الانضمام: edsbas.2ED34278
قاعدة البيانات: BASE