التفاصيل البيبلوغرافية
| العنوان: |
Cognitive function, self-management, and outcomes among liver transplant recipients: LivCog, a multicenter, prospective study |
| المؤلفون: |
Serper, Marina, Chafale, Adwait, Burdzy, Alex, Kim, Minjee, Asrani, Sumeet K., Yoshino Benavente, Julia, Gershon, Richard, Reese, Peter P., Schaubel, Douglas E., Boike, Justin R., Blanco, Maria C., Wolf, Michael S. |
| المصدر: |
Hepatology Communications ; volume 7, issue 10 ; ISSN 2471-254X |
| بيانات النشر: |
Ovid Technologies (Wolters Kluwer Health) |
| سنة النشر: |
2023 |
| الوصف: |
Liver transplantation is a life-saving option for decompensated cirrhosis. Liver transplant recipients require advanced self-management skills, intact cognitive skills, and care partner support to improve long-term outcomes. Gaps remain in understanding post-liver transplant cognitive and health trajectories, and patient factors such as self-management skills, care partner support, and sleep. Our aims are to (1) assess pre-liver transplant to post-liver transplant cognitive trajectories and identify risk factors for persistent cognitive impairment; (2) evaluate associations between cognitive function and self-management skills, health behaviors, functional health status, and post-transplant outcomes; and (3) investigate potential mediators and moderators of associations between cognitive function and post-liver transplant outcomes. LivCog is a longitudinal, prospective observational study that will enroll 450 adult liver transplant recipients and their caregivers/care partners. The duration of the study is 5 years with 24 additional months of patient follow-up. Data will be collected from participants at 1, 3, 12, and 24 months post-transplant. Limited pre-liver transplant data will also be collected from waitlisted candidates. Data collection methods include interviews, surveys, cognitive assessments, and actigraphy/sleep diary measures. Patient measurements include sociodemographic characteristics, pretransplant health status, cognitive function, physical function, perioperative measures, medical history, transplant history, self-management skills, patient-reported outcomes, health behaviors, and clinical outcomes. Caregiver measures assess sociodemographic variables, health literacy, health care navigation skills, self-efficacy, care partner preparedness, nature and intensity of care, care partner burden, and community participation. By elucidating various health trajectories from pre-liver transplant to 2 years post-liver transplant, LivCog will be able to better characterize recipients at higher risk of ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1097/hc9.0000000000000259 |
| DOI: |
10.1097/HC9.0000000000000259 |
| الإتاحة: |
https://doi.org/10.1097/hc9.0000000000000259Test |
| حقوق: |
http://creativecommons.org/licenses/by-nc-nd/4.0Test/ http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
| رقم الانضمام: |
edsbas.7AD68EB7 |
| قاعدة البيانات: |
BASE |
