المؤلفون: Wing-Kee Lee, Michelle Maaß, Amy Quach, Nataliya Poscic, Holly Prangley, Erin-Claire Pallott, Jiyoon L. Kim, Jason S. Pierce, Besim Ogretmen, Anthony H. Futerman, Frank Thévenod

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: TG, thapsigargin, Male, cancer drug resistance, FASN, fatty acid synthase, Biochemistry, ERAD, ER-associated degradation, UPR, unfolded protein response, MDR, multidrug resistance, Tandem Mass Spectrometry, Sphingosine N-Acyltransferase, Tumor Microenvironment, HERPUD1, homocysteine-inducible ER protein with ubiquitin-like domain 1, GRP78, glucose-regulated protein 78 kDa, unfolded protein response, Endoplasmic Reticulum-Associated Degradation, Kidney Neoplasms, XBP1, X-box binding protein 1, lipids (amino acids, peptides, and proteins), Female, ABC transporter, ATP6α, activating transcription factor 6α, Research Article, ATP Binding Cassette Transporter, Subfamily B, PDIA4, protein disulfide isomerase family A member 4, P-glycoprotein, CHOP, C/EBP homologous protein, Ceramides, ACACA, acetyl-CoA carboxylase alpha, ER, endoplasmic reticulum, VLC, very long chain, LCC, long-chain ceramide, HPCT, human proximal convoluted tubule, Humans, RNA, Messenger, TUN, tunicamycin, Molecular Biology, Sphingolipids, SM, sphingomyelin, UCSC, University of California, Santa Cruz, SREBP, sterol-regulatory element binding protein, LD, lipid domain, Tumor Suppressor Proteins, Membrane Proteins, Cell Biology, DOX, doxorubicin, Doxorubicin, Drug Resistance, Neoplasm, Mff, mitochondrial fission factor, CerS, ceramide synthase, HMGCL, 3-hydroxymethyl-3-methylglutaryl-CoA lyase, TM, transmembrane

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1819640a96f5d4d5386b5634e205d7Test
http://europepmc.org/articles/PMC8804196Test

المؤلفون: Thomas O. Metz, Iris D. Zelnik, Lisa M. Bramer, Eric Barklis, R. Max Petty, Kent J. Bloodsworth, Jennifer E. Kyle, Ayna Alfadhli, Anthony H. Futerman, Robin Lid Barklis, Fikadu G. Tafesse, Hans C. Leier

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, viruses, β-gal, β-galactosidase, HIV Infections, Biochemistry, chemistry.chemical_compound, NIH, National Institutes of Health, PIP2, phosphatidyl-4,5-bisphosphate, BME, β-mercaptoethanol, Sphingosine N-Acyltransferase, Ceramide synthase, CA, capsid, Infectivity, biology, Chemistry, Ceramide synthase 2, virus diseases, PS, phosphatidylserine, Cell biology, Vesicular stomatitis virus, PM, plasma membrane, PrGag, precursor Gag, SL, sphingolipid, Sphingomyelin, Research Article, Ceramide, CT, cytoplasmic tail, VSV, vesicular stomatitis virus, HexCer, hexosylceramide, Ceramides, 03 medical and health sciences, G, glycoprotein, fusion protein, Humans, ceramide, Molecular Biology, 030102 biochemistry & molecular biology, Tumor Suppressor Proteins, Membrane Proteins, HIV, Cell Biology, Virus Internalization, HEK293T, human embryonic kidney 293T, biology.organism_classification, Fusion protein, Sphingolipid, ceramide synthase, 030104 developmental biology, HEK293 Cells, CerS, ceramide synthase, Env, envelope, HIV-1, sphingolipid, Gene Deletion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95d3b26a57ef253f47dc2293f746c62Test
https://pubmed.ncbi.nlm.nih.gov/33515546Test

المؤلفون: Hirotaka Goto, Masatoshi Miyamoto, Akio Kihara

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, S1PR, sphingosine-1-phosphate receptor, channel, MEDEP, mouse ES cell-derived erythroid progenitor line, Biochemistry, chemistry.chemical_compound, Gene Knockout Techniques, PC, phosphatidylcholine, Sph, sphingosine, Sphingosine, HUVEC, human umbilical vein endothelial cell, PA, phosphatidic acid, CERS, ceramide synthase, PS, phosphatidylserine, PLPP, phospholipid phosphatase, Cell biology, Endothelial stem cell, transporter, endothelial cell, phospholipid phosphatase, lipids (amino acids, peptides, and proteins), TKO, triple KO, Research Article, Pi, orthophosphoric acid, SPNS2, sphingolipid transporter 2, Ceramide, HDL, high-density lipoprotein, PE, phosphatidylethanolamine, PI, phosphatidylinositol, Cell Line, Dephosphorylation, 03 medical and health sciences, FBS, fetal bovine serum, lipid, Extracellular, Animals, Humans, Sphingosine-1-phosphate, ceramide, Molecular Biology, S1P, sphingosine-1-phosphate, 030102 biochemistry & molecular biology, organic chemicals, Biological Transport, MFSD2B, major facilitator superfamily domain containing 2B, Cell Biology, Lipid signaling, Sphingolipid, PAP, phosphatidic acid phosphatase, Phosphoric Monoester Hydrolases, 030104 developmental biology, chemistry, phosphatidylethanolamine, LPP, lipid phosphate phosphatase, sphingosine-1-phosphate, BSA, bovine serum albumin, erythrocyte, sphingolipid, Lysophospholipids, UPLC, ultra–high performance liquid chromatography, HA, hemagglutinin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a7214694a034a295f8e3c91cc65849Test
http://hdl.handle.net/2115/83044Test

المؤلفون: Gergely Karsai, Thorsten Hornemann, Arnold von Eckardstein, Regula Steiner, Andres Kaech, Museer A. Lone

المساهمون: University of Zurich, Hornemann, Thorsten

المصدر: Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100122-(2021)

مصطلحات موضوعية: 1303 Biochemistry, cell migration, SPTLC1, serine palmitoyltransferase long-chain base subunit 1, SO, sphingosine, Biochemistry, 1307 Cell Biology, Mice, chemistry.chemical_compound, Endocrinology, LCB, long-chain base, fumonisin B1, Cell Movement, 540 Chemistry, Hereditary Sensory and Autonomic Neuropathies, Cells, Cultured, 10038 Institute of Clinical Chemistry, HSAN1, hereditary sensory neuropathy type 1, Cell migration, functional lipidomics, SA, sphinganine, 1310 Endocrinology, Cell biology, SL, sphingolipid, Intracellular, Research Article, Ceramide, Cell type, FB1, fumonisin B1, 1-deoxySA, 1-deoxy-sphinganine, T2DM, 610 Medicine & health, QD415-436, FADS3, fatty acid desaturase 3, 1-deoxy-sphingolipids, Animals, ceramide, Sphingosine-1-phosphate, 1-deoxySO, 1-deoxy-sphingosine, SPTLC1, HPF, high-pressure frozen, S1P, sphingosine-1-phosphate, EM, electron microscopy, Sphingolipids, EA, Epon/Araldite, Sphingosine, Golgi, Golgi apparatus, Serine C-palmitoyltransferase, T2DM, type 2 diabetes mellitus, Cell Biology, Fibroblasts, 1-deoxySL, 1-deoxy-sphinglipid, SPT, serine palmitoyltransferase, ceramide synthase, live cell imaging, Diabetes Mellitus, Type 2, chemistry, CerS, ceramide synthase, NIH 3T3 Cells, sphingolipid, metabolism

وصف الملف: PIIS0022227521001048.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d1383c8147711111b721da3a2dc237Test
https://doi.org/10.1016/j.jlr.2021.100122Test

المؤلفون: Nawajes A Mandal, Sandip K. Basu, Richard C. Grambergs, Bano Qaladize, M. Victoria Simón, Nora P. Rotstein

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100037-(2021)
Journal of Lipid Research
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: 0301 basic medicine, RETINITIS PIGMENTOSA, genetic structures, DR, diabetic retinopathy, DHCer, dihydroceramide, Physiology, 030204 cardiovascular system & hematology, Biochemistry, AH, aqueous humor, purl.org/becyt/ford/1 [https], ASAH, N-acyl-sphingosine amidohydrolase, S1PR, S1P receptor, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Sph, sphingosine, AMD, age-related macular degeneration, GCS, glucosylceramide synthase, ceramide-1-phosphate, CDase, ceramidase, music.instrument, C1P, ceramide 1-phosphate, AGE-RELATED MACULAR DEGENERATION, PARP-1, poly-ADP ribose polymerase 1, purl.org/becyt/ford/3.1 [https], SphK, sphingosine kinase, SPT, serine palmitoyl transferase, VEGF, vascular endothelial growth factor, medicine.anatomical_structure, OAG, open-angle glaucoma, BDNF, brain-derived neurotrophic factor, SMS, SM synthase, purl.org/becyt/ford/3 [https], lipids (amino acids, peptides, and proteins), CerK, ceramide kinase, Thematic Review Series: Seeing 2020: Lipids and Lipid-Soluble Molecules in the Eye, Ceramide, RPE, retinal pigment epithelium, GlcCer, glucosylceramide, NGF, nerve growth factor, HexCer, hexosylceramide, Cer, ceramide, PDR, proliferative diabetic retinopathy, QD415-436, GalCer, galactosylceramide, CFH, complement factor H, VMD, vitelliform macular dystrophy, 03 medical and health sciences, Lactosylceramide, nSMase, neutral sphingomyelinase, retinitis pigmentosa, BEST1, bestrophin-1, PKC, protein kinase C, Retinitis pigmentosa, medicine, ceramide, Sphingosine-1-phosphate, purl.org/becyt/ford/1.6 [https], RP, retinitis pigmentosa, music, age-related macular degeneration, photoreceptor degeneration, Sphingolipids, Retina, Retinal pigment epithelium, SPHINGOSINE-1-PHOSPHATE, hBest1, human bestrophin-1, CERAMIDE, aSMase, acid SMase, business.industry, EAU, experimental autoimmune uveoretinitis, Thematic Review Series, Retinal, Cell Biology, medicine.disease, PHOTORECEPTOR DEGENERATION, IOP, intraocular pressure, Sphingolipid, CERAMIDE-1-PHOSPHATE, eye diseases, 030104 developmental biology, GA, geographic atrophy, chemistry, CerS, ceramide synthase, sphingosine-1-phosphate, LacCer, lactosylceramide, ADIPOR1, adiponectin receptor 1, sense organs, Mac Tel, macular telangiectasia, business, POAG, primary open-angle glaucoma, CERKL, ceramide kinase-like

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639e875fa28547227b078cf550989119Test
https://doi.org/10.1194/jlr.tr120000972Test

المؤلفون: Campana, Mélanie, Bellini, Lara, Rouch, Claude, Rachdi, Latif, Coant, Nicolas, Butin, Noémie, Bandet, Cécile, Philippe, Erwann, Meneyrol, Kelly, Kassis, Nadim, Dairou, Julien, Hajduch, Eric, Colsch, Benoit, Magnan, Christophe, Le Stunff, Hervé

المساهمون: Unité de Biologie Fonctionnelle et Adaptative (BFA (UMR_8251 / U1133)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche Croissance et signalisation (UMR_S 845), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Métabolisme des Médicaments (LEMM), Service de Pharmacologie et Immunoanalyse (SPI), Médicaments et Technologies pour la Santé (MTS), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Médicaments et Technologies pour la Santé (MTS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche des Cordeliers (CRC), Université Pierre et Marie Curie - Paris 6 (UPMC)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), École pratique des hautes études (EPHE), Hajduch, Eric

المصدر: Molecular metabolism
Molecular metabolism, Elsevier, 2018, 8, pp.23-36. ⟨10.1016/j.molmet.2017.10.013⟩
Molecular Metabolism, Vol 8, Iss, Pp 23-36 (2018)
Molecular metabolism, 2018, 8, pp.23-36. ⟨10.1016/j.molmet.2017.10.013⟩
Molecular Metabolism

مصطلحات موضوعية: OZR, Obese Zucker rat, Blood Glucose, lcsh:Internal medicine, Hypothalamus, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Ceramides, d4-palmitate, Deuterium-labeled palmitate, Cell Line, ER, endoplasmic reticulum, Ceramide, Mice, IR, insulin resistance, HFD, high fat diet, Thr-308, Threonine 308, Insulin-Secreting Cells, M, myriocin, Animals, Insulin, Obesity, Hypotalamus, lcsh:RC31-1245, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Cells, Cultured, ComputingMilieux_MISCELLANEOUS, ICV, intracerebroventricular, Ser-473, Serine 473, C2-Cer, C2-Ceramide, LZR, Lean Zucker rat, Insulin secretion, PKCs, proteins kinase C, T2D, Type 2 diabetes mellitus, DH-C2-cer, dihydroceramide, Insulin resistance, SPT2, Serine-palmitoyl transferase 2, Rats, Rats, Zucker, CerS, ceramide Synthase, Original Article, Lipotoxicity, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fd4a4826ebe9c43d17b824d86cdbb5cfTest
https://hal.archives-ouvertes.fr/hal-02450789Test

المؤلفون: Mototeru Yamane

المصدر: Biochimie Open
Biochimie Open, Vol 1, Iss C, Pp 11-27 (2015)

مصطلحات موضوعية: Necrosis, Research paper, acridine orange, 3,6-Bis(dimethylamino) acridine hydrochloride, CathB, cathepsin B, 4-HPR, N-(4-hydroxyphenyl)retinamide, ([13C16]C16:0-CoA, palmitoyl-13C16 coenzyme A, Biochemistry, Cathepsin B, chemistry.chemical_compound, SIM, selected-ion monitoring, C2:0-CoA, acetyl-coenzyme A, DL-PDMP, DL-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, lcsh:QD415-436, A549 cells, Ser, Serine, IS, internal standard, CHOP, CAAT/enhancer binding protein homologous protein, DMEM, Dulbecco's modified Eagle's medium, ESI, electrospray ionization, LDH, lactate dehydrogenase, [1,2,3,4-13C4]C16:0 acid, palmitic acid-1,2,3,4-13C4, APCI, atmospheric pressure chemical ionization, SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, [2-13C]C2:0 acid, sodium acetate-2-13C, SPTLC, SPT-long chain base subunit, d18:1-[D31]C16:0-Cer, N-palmitoyl [D31]-D-erythro-sphingosine, Lys, lysosomes, Ceramidase, Cell biology, lipids (amino acids, peptides, and proteins), medicine.symptom, D-NMAPPD, D-NMAPPD, N-[(1R,2R)-2-hydroxy-1-(hydroxy-methyl)-2-(4-nitrophenyl)ethyl]tetradecanamide, Ceramide, C16:0-CoA, palmitoyl-coenzyme A, DMSO, dimethylsulfoxide, SDS, sodium dodecyl sulfate, GlcCer, glucosylceramide, Palmitoyl-ceramide, Cer, ceramide, [D7]d18:1, D-erythro-sphingosine-D7, Biology, Myriocin, 2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid, C16:0-Cer, palmitoyl-ceramide, lcsh:Biochemistry, ER, endoplasmic reticulum, L-[2,3,3-D3]Ser, L-serine-2,3,3-D3, FBS, fetal bovine serum, Survivin, medicine, d18:1, sphingosine, DL-PDMP, LC3, microtubule-associated protein 1 light chain 3B, A549 cell, SM, sphingomyelin, Cell growth, SPT, serine palmitoyltransferase, [D7]d18:0, D-erythro-sphinganine-D7, LMP, lysosomal membrane permeabilization, FATP1, fatty acid transport protein 1, carbohydrates (lipids), Sphinganine, chemistry, Apoptosis, DTT, dithiothreitol, CerS, ceramide synthase, BSA, bovine serum albumin, d18:0, sphinganine, MAM, mitochondria-associated membrane, DAPI, 4′,6-diamidino-2-phenylindole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0962d08fecd59ada8b59d83f4d72ace7Test
http://europepmc.org/articles/PMC5889477Test