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1مؤتمر
المؤلفون: Juarez-Alvarez, Omar, Franci, Alessio
المصدر: urn:isbn:978-1-66543-659-5
60th IEEE Conference on Decision and Control, CDC 2021 (2021); 2021 60th IEEE Conference on Decision and Control (CDC), Austin, Usa [Usa], 13-12-2021 => 17-12-2021مصطلحات موضوعية: Adjacency matrix, Cellular levels, Cellulars, Coupled oscillators, Feedback mechanisms, In-phase, In-phase oscillations, Network level, Network oscillations, Synaptic coupling, Control and Systems Engineering, Modeling and Simulation, Control and Optimization, Engineering, computing & technology, Ingénierie, informatique & technologie
الوصول الحر: https://orbi.uliege.be/handle/2268/303278Test
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2دورية أكاديمية
مصطلحات موضوعية: Quantum Physics, Physical Sciences, Physical Injury - Accidents and Adverse Effects, Traumatic Head and Spine Injury, Traumatic Brain Injury (TBI), Neurosciences, Bioengineering, Brain Disorders, Injuries and accidents, Neurological, Astrocytes, bTBI, LIS, QPM, TBI, Micromanipulators, Shock waves, Cellular levels, Exact functional, External shocks, Laser induced shock wave, Mechanical force, Quantitative phase microscopies, Traumatic Brain Injuries, Whole process, Brain, Communications engineering, Electronics, sensors and digital hardware, Atomic, molecular and optical physics
وصف الملف: application/pdf
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3دورية أكاديمية
المؤلفون: Dou Dou (12025312), Yanyan Diao (1655920), Wenjie Sha (12025315), Rongrong Su (12025318), Linjiang Tong (213513), Wenjie Li (6558), Limin Leng (6108116), Lijuan Xie (1602031), Zhixiao Yu (12025321), Haoming Song (848555), Zihao Shen (11518000), Lili Zhu (219363), Zhenjiang Zhao (1655923), Hua Xie (49932), Zhuo Chen (135585), Honglin Li (19441), Yufang Xu (1655929)
مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, >)‑ one derivatives, >)- one derivatives, 937 xenograft models, attractive therapeutic target, noncovalent btk inhibitors, 24a , 50 , covalent btk inhibitors, 7 ( 8, selective inhibitors, h <, target inhibition, 50 mg, tyrosine kinase, platelet dysfunction, kg dosage, high selectivity, cellular levels, bruton ’
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4دورية أكاديمية
المؤلفون: Zhang-Xu He (11872120), Qi An (331241), Bo Wei (188204), Wen-Juan Zhou (1484746), Bing-Fei Wei (11872123), Yun-Peng Gong (11872126), Xin Zhang (35492), Ge Gao (5909), Guan-Jun Dong (11872129), Jin-Ling Huo (11872132), Xin-Hui Zhang (1491649), Fei-Fei Yang (585760), Hong-Min Liu (668537), Li-Ying Ma (1648447), Wen Zhao (302324)
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, isolated cardiac fibroblasts, important therapeutic target, cullin 3 neddylation, catalyzing cullin neddylation, anticardiac fibrotic effects, cellular thermal shift, specifically targeted dcn1, potentially unrecognized role, molecular modeling studies, 2 , cellular levels, yielding compound, previous work, pressure overload, performed based, mouse hearts, lead compound, immunoprecipitation assays, human diseases, first found, findings indicate, e3 ligase
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5دورية أكاديمية
المؤلفون: Bin Zhou (84959), Xiaofei Liang (843086), Husheng Mei (11581149), Shuang Qi (1502860), Zongru Jiang (3745834), Aoli Wang (1319265), Fengming Zou (1586605), Qingwang Liu (791358), Juan Liu (6492), Wenliang Wang (1233804), Chen Hu (317374), Yongfei Chen (1319262), Zuowei Wang (333190), Beilei Wang (298371), Li Wang (15202), Jing Liu (38537), Qingsong Liu (381059)
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Chemical Sciences not elsewhere classified, zeste homologue 2, zeste homolog 2, cellular levels led, apparent inhibitory activity, 30 μm ), go related gene, epz6438 (< b, 29 , 3 nm ), showed better efficacy, ezh2 mutant cancers, 50 , 1 , 1 nm, h3k27 ), ́- go, solid tumors, oral administration, inhibited ezh2, human ether, histone methyltransferases, high selectivity, hematologic malignancies
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6رسالة جامعية
المؤلفون: Tavares, Lucas Alves
مرشدي الرسالة: Silva, Luis Lamberti Pinto da
مصطلحات موضوعية: 2 depletion, acts in the CD4 down-regulation induced by Nef. These studies contribute to a better understanding on the molecular mechanisms involved in Nef activit, although not need charging ubiquitination, and it is estimated that there are currently at least 36.9 million people infected with the virus. During the replication cycle, and only the AP-1 variant comprising ?2, another subunit of AP-1, AP-1, AP-1 subunits. By pull-down technique, AP-2, AP-2 and AP-3 are potentially heterogeneous due to the existence of multiple subunits isoforms encoded by different genes. However, AP-3 complexes and Nef does not appear to interact with AP-4 and AP-5 subunits. However, being an important protein in the endo-lysosomal system. Furthermore, but also seem to compose AP-1 complex with distinct cell functions, but not ?1, but not ?1 depletion, but the molecular mechanisms are still incompletely understood. Nef forms a tripartite complex with the cytosolic tail of the CD4 and adapter protein, by flow cytometry assay, compromises the reduction of surface CD4 levels induced by Nef. Immunofluorescence microscopy analysis also revealed that ?2 depletion impairs the red, compromising the efficient CD4 degradation by Nef. Moreover, depends on the proteins from ESCRTs (Endosomal Sorting Complexes Required for Transport) machinery and the action of Alix, an accessory protein ESCRT, ESCRT, HIV promotes several changes in the physiology of the host cell to promote their survival and enhance replication. The fast progression of HIV-1 in hu, HIV-1, inducing CD4 internalization and lysosome degradation. Previous research has demonstrated that CD4 target to lysosomes by Nef involves targeting of th, internalized CD4 accumulates in enlarged HRS-GFP positive endosomes, is required in Nef-mediated targeting of CD4 to lysosomes and the ?2 participation in this process is conserved by Nef from different viral strains. F, MVB, Nef, not ?1-adaptin, one is the most important is the down-regulation of proteins from the immune response, our data from immunoblots indicated that ?2- adaptin, regulação negativa de CD4, resulted in decreased cellular levels of ?1 and ?2 and, resulting in CD4 accumulation in primary endosomes. Knockdown of ?1A, such as the CD4 receptor. It is known that this action causes CD4 degradation in lysosome, the results indicate that ?-adaptins isoforms not only have different functions, the results indicate that ?2-adaptin is a molecule that is essential for CD4 targeting by Nef to ESCRT/MVB pathway, The Human Immunodeficiency Virus (HIV) is the etiologic agent of Acquired Immunodeficiency Syndrome (AIDS). AIDS is a disease which has a global distr, the role of Nef interaction with AP-1 or AP-3 in CD4 down-regulation is poorly understood. Furthermore, there are few studies to demonstrate if the different combinations of APs isoforms are form and if they have distinct functional properties. This stud, this study aimed to characterize the involvement of AP-1 complex in the down-regulation of CD4 by Nef HIV-1 through the functional study of the two is, this work contributes with the understanding of primordial process regulation on intracellular trafficking of transmembrane proteins., upon artificially stabilizing ESCRT-I in early endosomes, via overexpression of HRS, we showed that Nef is able to interact with ?2. In addition, where co-localize with ?2. Together, which may also help to improve the understanding of the HIV pathogenesis and the related syndrome. In addition, y1-adaptina, y2-adaptina
وصف الملف: application/pdf
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7دورية أكاديمية
المؤلفون: Behrooz eDarbani, Shahin eNoeparvar, Søren eBorg
المصدر: Frontiers in Plant Science, Vol 7 (2016)
مصطلحات موضوعية: Micronutrients, Mitochondria, leaves, circular RNAs, transfer cells, cellular levels, Plant culture, SB1-1110
وصف الملف: electronic resource
العلاقة: http://journal.frontiersin.org/Journal/10.3389/fpls.2016.00776/fullTest; https://doaj.org/toc/1664-462XTest
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8
المؤلفون: Dalvi-Isfahan, Mohsen, Jha, Piyush, Tavakoli, Javad, Daraei-Garmakhany, Amir, Xanthakis, Epameinondas, Le-Bail, Allain
المصدر: Journal of Food Engineering. 255:50-60
مصطلحات موضوعية: Cryoconcentration, Freeze burn, Freeze damage, Mechanical damage, Microscopy, Recrystallization, Crystallization, Damage detection, Food preservation, Food products, Freezing, Ice, Microscopic examination, Microstructure, Morphology, Thermal processing (foods), Cellular levels, Cellular structure, Chemical change, Freezing process, Mechanical damages, Physical damages, Food storage
وصف الملف: print
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9دورية أكاديمية
المؤلفون: Sanchez-Pino, Maria Dulfary
المصدر: School of Medicine Faculty Publications
مصطلحات موضوعية: Cellular levels of ROS, Flow cytometry, Fluorescence-activated cell sorting (FACS), Immunophenotyping, Intracellular arginase-1, MDSC, Myeloid-derived suppressor cells, Medical Genetics, Medical Physiology, Oncology
العلاقة: https://digitalscholar.lsuhsc.edu/som_facpubs/1504Test; https://doi.org/10.1007/978-1-0716-1948-3_17Test
الإتاحة: https://doi.org/10.1007/978-1-0716-1948-3_17Test
https://digitalscholar.lsuhsc.edu/som_facpubs/1504Test -
10تقرير
المؤلفون: 柴田 幹大, Shibata Mikihiro
مصطلحات موضوعية: タンパク質, バイオイメージング, 原子間力顕微鏡, 画像解析, Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
العلاقة: https://kaken.nii.ac.jp/ja/search/?kw=80631027Test; https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-18K19287Test/; https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-18K19287/18K19287seikaTest/; https://kanazawa-u.repo.nii.ac.jp/?action=repository_uri&item_id=52830Test; http://hdl.handle.net/2297/00059123Test; 令和1(2019)年度 科学研究費補助金 挑戦的研究(萌芽) 研究成果報告書 = 2019 Fiscal Year Final Research Report, 2018-06-29 – 2020-03-31, 9p.(2020-05-29); https://kanazawa-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=52830&item_no=1&attribute_id=26&file_no=1Test
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