المؤلفون: Lindsey T. Brinton, Pu Zhang, Katie Williams, Daniel Canfield, Shelley Orwick, Steven Sher, Ronni Wasmuth, Larry Beaver, Casey Cempre, Jordan Skinner, Matthew Cannon, Mukul Govande, Bonnie Harrington, Amy Lehman, John C. Byrd, Rosa Lapalombella, James S. Blachly

المصدر: Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: Gilteritinib, Midostaurin, Synergy, Combination therapy, FLT3, BCL2, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s13045-020-00973-4Test; https://doaj.org/toc/1756-8722Test

الوصول الحر: https://doaj.org/article/f9792135e55a4ec59d467892727b81d0Test

المؤلفون: Lindsey T. Brinton, Steven Sher, Katie Williams, Daniel Canfield, Shelley Orwick, Ronni Wasmuth, Casey Cempre, Jordan Skinner, Amy Lehman, James S. Blachly, John C. Byrd, Rosa Lapalombella

المصدر: Cancers, Vol 12, Iss 6, p 1574 (2020)

مصطلحات موضوعية: AML, FLT3, XPO1, CRISPR-Cas9 screening, synergism, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6694/12/6/1574Test; https://doaj.org/toc/2072-6694Test

الوصول الحر: https://doaj.org/article/c66048c7b4ad4701bac8721753c538c8Test

المؤلفون: Lindsey T. Brinton (3169368), Pu Zhang (51027), Katie Williams (6166097), Daniel Canfield (9538049), Shelley Orwick (8371137), Steven Sher (9538052), Ronni Wasmuth (8371146), Larry Beaver (9538055), Casey Cempre (9538058), Jordan Skinner (9538061), Matthew Cannon (5907527), Mukul Govande (5104676), Bonnie Harrington (9538064), Amy Lehman (364347), John C. Byrd (14625), Rosa Lapalombella (8371152), James S. Blachly (9538067)

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Cancer, Hematology, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Gilteritinib, Midostaurin, Synergy, Combination therapy, FLT3, BCL2, Venetoclax, Acute myeloid leukemia

العلاقة: https://figshare.com/articles/presentation/Additional_file_1_of_Synergistic_effect_of_BCL2_and_FLT3_co-inhibition_in_acute_myeloid_leukemia/13114679Test

الإتاحة: https://doi.org/10.6084/m9.figshare.13114679.v1Test

المؤلفون: Lindsey T. Brinton (3169368), Pu Zhang (51027), Katie Williams (6166097), Daniel Canfield (9538049), Shelley Orwick (8371137), Steven Sher (9538052), Ronni Wasmuth (8371146), Larry Beaver (9538055), Casey Cempre (9538058), Jordan Skinner (9538061), Matthew Cannon (5907527), Mukul Govande (5104676), Bonnie Harrington (9538064), Amy Lehman (364347), John C. Byrd (14625), Rosa Lapalombella (8371152), James S. Blachly (9538067)

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Cancer, Hematology, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Gilteritinib, Midostaurin, Synergy, Combination therapy, FLT3, BCL2, Venetoclax, Acute myeloid leukemia

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_2_of_Synergistic_effect_of_BCL2_and_FLT3_co-inhibition_in_acute_myeloid_leukemia/13114682Test

الإتاحة: https://doi.org/10.6084/m9.figshare.13114682.v1Test

المؤلفون: Amy S. Ruppert, Larry Beaver, Bonnie K. Harrington, Janek S. Walker, Brandi R. Walker, Katie Williams, James Cronin, Zachary A. Hing, Alexander Pan, Jordan N. Skinner, Jennifer A. Woyach, Nyla A. Heerema, Steven Sher, Amy Lehman, Charles Thomas Gregory, Vincenzo Coppola, Rosa Lapalombella, Krzysztof Mrózek, Max Yano, Pearlly S. Yan, Hatice Gulcin Ozer, James S. Blachly, Jadwiga Labanowska, John C. Byrd, Casey Cempre

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

مصطلحات موضوعية: Adult, Male, Chronic lymphocytic leukaemia, Genes, Immunoglobulin Heavy Chain, Chronic lymphocytic leukemia, Science, General Physics and Astronomy, Chromosomal translocation, Biology, Article, Translocation, Genetic, General Biochemistry, Genetics and Molecular Biology, Pathogenesis, Mice, chemistry.chemical_compound, immune system diseases, B-Cell Lymphoma 3 Protein, Proto-Oncogene Proteins, hemic and lymphatic diseases, medicine, Animals, Humans, Cyclin D1, Cancer models, neoplasms, Cancer genetics, B cell, Aged, Aged, 80 and over, Multidisciplinary, Cancer, Oncogenes, General Chemistry, Middle Aged, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Mice, Inbred C57BL, Leukemia, medicine.anatomical_structure, Gene Expression Regulation, Proto-Oncogene Proteins c-bcl-2, chemistry, Ibrutinib, Cancer research, Female, CD5, Immunoglobulin Heavy Chains

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4020fc2f6408fa397a551b9d41261e40Test
https://doaj.org/article/810bfd0089064a989b380ab83b7f18b0Test

المؤلفون: Zachary A. Hing, Jennifer A. Woyach, Katie Williams, Kerry A. Rogers, Brian Giacopelli, Neil E. Kay, Jordan M. Baumhardt, Matthew K. Summers, Benjamin R. Stromberg, Sameer A. Parikh, Sharon Shacham, Janek S. Walker, Christopher C. Oakes, Rosa Lapalombella, Vincenzo Coppola, Thomas J. Kipps, Qingxiang Sun, Bonnie K. Harrington, Hatice Gulcin Ozer, Larry Beaver, Laura Z. Rassenti, Amy Lehman, Jordan N. Skinner, Yuh Min Chook, Casey Cempre, Lynne V. Abruzzo, John C. Byrd

المصدر: Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-21 (2021)
Journal of hematology & oncology, vol 14, iss 1

مصطلحات موضوعية: Nonsynonymous substitution, Male, Models, Molecular, Cancer Research, Lymphoma, Cytoplasmic and Nuclear, Chronic lymphocytic leukemia, Mutant, Receptors, Cytoplasmic and Nuclear, Selinexor, Cardiorespiratory Medicine and Haematology, Inbred C57BL, Sines, Epigenesis, Genetic, Mice, Models, Receptors, 2.1 Biological and endogenous factors, Chronic, Aetiology, Cancer, Leukemic, Leukemia, Gene Expression Regulation, Leukemic, Hematology, lcsh:Diseases of the blood and blood-forming organs, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Lymphocytic, Mutation analysis, Oncology, XPO1, Female, Oncology and Carcinogenesis, Biology, Karyopherins, lcsh:RC254-282, Mouse model, Rare Diseases, Genetic, Genetics, medicine, Animals, Humans, Neoplastic transformation, Epigenetics, Molecular Biology, Expression profiling, Retrospective Studies, lcsh:RC633-647.5, Point mutation, Research, B-Cell, Wild type, Molecular, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Mice, Inbred C57BL, Gene Expression Regulation, Mutation, Cancer research, Transcriptome, Epigenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6b45569723f9693a4cbbbded7307c8Test
http://europepmc.org/articles/PMC7809770Test

المؤلفون: James S. Blachly, Shelley Orwick, Jordan N. Skinner, Steven Sher, Katie Williams, Matthew Cannon, Amy Lehman, Daniel Canfield, Lindsey T. Brinton, Pu Zhang, Bonnie K. Harrington, Rosa Lapalombella, Casey Cempre, John C. Byrd, Mukul Govande, Larry Beaver, Ronni Wasmuth

المصدر: Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, Mice, SCID, Targeted therapy, Gene Knockout Techniques, chemistry.chemical_compound, fluids and secretions, 0302 clinical medicine, hemic and lymphatic diseases, Medicine, CRISPR, Midostaurin, FLT3, Sulfonamides, Aniline Compounds, Hematology, Myeloid leukemia, Gilteritinib, hemic and immune systems, lcsh:Diseases of the blood and blood-forming organs, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Synergy, Leukemia, Myeloid, Acute, Proto-Oncogene Proteins c-bcl-2, Oncology, Pyrazines, 030220 oncology & carcinogenesis, embryonic structures, Female, Rapid Communication, BCL2, medicine.medical_specialty, Combination therapy, Antineoplastic Agents, lcsh:RC254-282, Venetoclax, 03 medical and health sciences, In vivo, Cell Line, Tumor, Internal medicine, Animals, Humans, Protein Kinase Inhibitors, Molecular Biology, Acute myeloid leukemia, lcsh:RC633-647.5, business.industry, Genetic Therapy, Bridged Bicyclo Compounds, Heterocyclic, Staurosporine, 030104 developmental biology, fms-Like Tyrosine Kinase 3, chemistry, Cancer research, CRISPR-Cas Systems, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41325df92804a780f7d8c154d2728ccTest
https://doi.org/10.1186/s13045-020-00973-4Test

المؤلفون: Tzyy-Jye Doong, Nicole Grieselhuber, Nyla A. Heerema, Gerard Lozanski, Cecelia R. Miller, Karilyn Larkin, Tierney Kauffman, Rosa Lapalombella, Arletta Lozanski, John C. Byrd, Clara D. Bloomfield, Casey Cempre, Shelley Orwick, Bhavana Bhatnagar, Alice S. Mims, Lynne V. Abruzzo, Gregory K. Behbehani, Eileen Hu, Virginia M. Goettl, Alison Walker, Steven Sher, Pu Zhang, Caner Saygin, Jordan N. Skinner, James S. Blachly, Jadwiga Labanowska, Deedra Nicolet

المصدر: Leukemia

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Biology, Somatic evolution in cancer, Article, Acute myeloid leukaemia, Immunophenotyping, Clonal Evolution, 03 medical and health sciences, Young Adult, 0302 clinical medicine, medicine, Biomarkers, Tumor, Humans, Cancer genetics, Aged, Aged, 80 and over, Myeloid leukemia, Hematopoietic stem cell, Correction, Hematology, Genomics, Amplicon, Middle Aged, medicine.disease, Flow Cytometry, Hematopoietic Stem Cells, Prognosis, Haematopoiesis, Leukemia, Leukemia, Myeloid, Acute, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, DNA methylation, Mutation, Cancer research, Neoplastic Stem Cells, Female, Stem cell, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7eae162980dfd0939ef606772acafdTest
https://pubmed.ncbi.nlm.nih.gov/34480107Test

المؤلفون: Brandi R. Walker, Rosa Lapalombella, John C. Byrd, Casey Cempre, Jordan N. Skinner, Janek S. Walker

المصدر: Blood. 138:1542-1542

مصطلحات موضوعية: XPO1, T cell repertoire, hemic and lymphatic diseases, Immunology, Cell Biology, Hematology, Biology, Biochemistry, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1e73b86f9859a7d728cf6bdba1a3ce36Test
https://doi.org/10.1182/blood-2021-152777Test

المؤلفون: Cecelia R. Miller, Alice S. Mims, Tierney Kauffman, Virginia M. Goettl, Gregory K. Behbehani, Jadwiga Labanowska, Clara D. Bloomfield, Pu Zhang, Nicole Grieselhuber, Lynne V. Abruzzo, Eileen Hu, Caner Saygin, Gerard Lozanski, Jordan N. Skinner, Casey Cempre, Alison Walker, Steven Sher, John C. Byrd, Karilyn Larkin, Bhavana Bhatnagar, Nyla A. Heerema, Tzyy-Jye Doong, James S. Blachly, Rosa Lapalombella, Deedra Nicolet, Arletta Lozanski, Shelley Orwick

المصدر: Leukemia. 35:3627-3627

مصطلحات موضوعية: Cancer Research, Oncology, Hierarchy (mathematics), Cancer genetics, Myeloid leukemia, Hematology, Computational biology, Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::32d8b8b7c2d43ec7fe04d585356d5ee7Test
https://doi.org/10.1038/s41375-021-01398-9Test