المؤلفون: Shave, Steven, Kasprowicz, Richard, Athar, Abdullah M., Vlachou, Denise, Carragher, Neil O., Nguyen, Cuong Q.

مصطلحات موضوعية: Quantitative Biology - Quantitative Methods, Computer Science - Machine Learning

الوصول الحر: http://arxiv.org/abs/2404.18960Test

المؤلفون: McDiarmid, Amina H, Gospodinova, Katerina O, Elliott, Richard J R, Dawson, John C, Graham, Rebecca E, El-Daher, Marie-Therese, Anderson, Susan M, Glen, Sophie C, Glerup, Simon, Carragher, Neil O, Evans, Kathryn L

المساهمون: Alzheimer’s Research UK, Scotland Network Centre, University of Edinburgh

المصدر: Brain Communications ; volume 6, issue 2 ; ISSN 2632-1297

الإتاحة: https://doi.org/10.1093/braincomms/fcae101Test
https://academic.oup.com/braincomms/article-pdf/6/2/fcae101/57292835/fcae101.pdfTest

المؤلفون: Hollis, Robert L., Elliott, Richard, Dawson, John C., Ilenkovan, Narthana, Matthews, Rosie M., Stillie, Lorna J., Oswald, Ailsa J., Kim, Hannah, Llaurado Fernandez, Marta, Churchman, Michael, Porter, Joanna M., Roxburgh, Patricia, Unciti-Broceta, Asier, Gershenson, David M., Herrington, C. Simon, Carey, Mark S., Carragher, Neil O., Gourley, Charlie

المساهمون: Target Ovarian Cancer, Cancer Research UK

المصدر: Gynecologic Oncology ; volume 186, page 42-52 ; ISSN 0090-8258

مصطلحات موضوعية: Obstetrics and Gynecology, Oncology

الإتاحة: https://doi.org/10.1016/j.ygyno.2024.03.029Test
https://api.elsevier.com/content/article/PII:S0090825824001859?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0090825824001859?httpAccept=text/plainTest

المؤلفون: Athanasiadis, Paschalis, Ravikumar, Balaguru, Elliott, Richard J. R., Dawson, John C., Carragher, Neil O., Clemons, Paul A., Johanssen, Timothy, Ebner, Daniel, Aittokallio, Tero

المساهمون: Institute for Molecular Medicine Finland, Computational Systems Medicine, Helsinki Institute of Life Science HiLIFE, Helsinki Institute for Information Technology, Tero Aittokallio / Principal Investigator, Bioinformatics, Research Programs Unit

مصطلحات موضوعية: Anticancer drug, Comprehensive characterization, Integrated analysis, Cancer, Sensitivity, Database, Dependencies, Hallmarks, Resource, Efficacy, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: The authors thank Dr. David Drewry (UNC Eshelman School of Pharmacy) for his critical review and useful comments on the manuscript draft, Dr. Jani Saarela (FIMM) for his help with the library construction and compound sourcing, and LifeArc for assistance in compound sourcing. We also acknowledge Professor Steven Pollard and Dr Gillian Morrison (University of Edinburgh) and the CRUK Glioma Cellular Genetic resource for the provision of patient-derived glioma stem cells. The authors acknowledge funding support from Cancer Research UK and the Brain Tumour Charity (grant REF: C42454/A28596) , Norwegian Cancer Society (grant 216104) , Helse Sor-Ost (grant 2020026) , Radium Hospital Foundation, and the Finnish Cancer Foundation. P.A.C. was supported in part by the National Cancer Institute's Cancer Target Discovery and Development (CTD boolean AND 2) Network (U01CA217848) .; Athanasiadis , P , Ravikumar , B , Elliott , R J R , Dawson , J C , Carragher , N O , Clemons , P A , Johanssen , T , Ebner , D & Aittokallio , T 2023 , ' Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells ' , iScience , vol. 26 , no. 7 , 107209 . https://doi.org/10.1016/j.isci.2023.107209Test; ORCID: /0000-0002-0886-9769/work/143862187; ORCID: /0000-0003-0500-533X/work/143862998; 1eff72b3-9e82-473a-879c-02c3189dc2b1; http://hdl.handle.net/10138/565920Test; 001060192600001

الإتاحة: http://hdl.handle.net/10138/565920Test

المؤلفون: Baillache, Daniel J., Valero Griñán, María Teresa, Lorente Macías, Álvaro, Bennett, David Jonathan, Elliott, Richard J. R., Carragher, Neil O., Unciti-Broceta, Asier

العلاقة: info:eu-repo/grantAgreement/EC/H2020/1046-2016; Baillache, D. J., Valero, T., Lorente-Macías, Á., Bennett, D. J., Elliott, R., Carragher, N., & Unciti-Broceta, A. (2023). Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against Glioblastoma cells. RSC Medicinal Chemistry.[DOI:10.1039/d3md00454f]; https://hdl.handle.net/10481/85552Test

الإتاحة: https://doi.org/10.1039/d3md00454fTest
https://hdl.handle.net/10481/85552Test

المؤلفون: Smer-Barreto, Vanessa, Quintanilla Cavia, Andrea, Elliott, Richard J. R., Dawson, John C., Sun, Jiugeng, Campa Fernández, Víctor Manuel, Lorente-Macías, Álvaro, Unciti-Broceta, Asier, Carragher, Neil O., Acosta Cobacho, Juan Carlos, Oyarzún, Diego A.

المساهمون: Universidad de Cantabria

المصدر: Nature Communications, 2023, 14, 3445

العلاقة: https://doi.org/10.1038/s41467-023-39120-1Test; PID2020-117860GB-I00; https://hdl.handle.net/10902/29781Test

الإتاحة: https://doi.org/10.1038/s41467-023-39120-1Test
https://hdl.handle.net/10902/29781Test

المؤلفون: Chrisochoidou, Yakinthi, Roy, Rajat, Farahmand, Pooyeh, Gonzalez, Guadalupe, Doig, Jennifer, Krasny, Lukas, Rimmer, Ella F, Willis, Anne E, MacFarlane, Marion, Huang, Paul H, Carragher, Neil O, Munro, Alison F, Murphy, Daniel J, Veselkov, Kirill, Seckl, Michael J, Moffatt, Miriam F, Cookson, William OC, Pardo, Olivier E

مصطلحات موضوعية: Animals, Mice, Humans, Mesothelioma, Malignant, Fibroblasts, Cancer-Associated Fibroblasts, Lung

وصف الملف: application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/363261Test

الإتاحة: https://www.repository.cam.ac.uk/handle/1810/363261Test

المؤلفون: Johanssen, Timothy, McVeigh, Laura, Erridge, Sara, Higgins, Geoffrey, Straehla, Joelle, Frame, Margaret, Aittokallio, Tero Antero, Carragher, Neil O., Ebner, Daniel

المصدر: 2234-943X.

العلاقة: Johanssen, Timothy McVeigh, Laura Erridge, Sara Higgins, Geoffrey Straehla, Joelle Frame, Margaret Aittokallio, Tero Antero Carragher, Neil O. Ebner, Daniel . Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia. Frontiers in Oncology. 2023, 12; http://hdl.handle.net/10852/106664Test; 2127239; info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Frontiers in Oncology&rft.volume=12&rft.spage=&rft.date=2023; Frontiers in Oncology; 12; https://doi.org/10.3389/fonc.2022.1075559Test

الإتاحة: https://doi.org/10.3389/fonc.2022.1075559Test
http://hdl.handle.net/10852/106664Test

المؤلفون: Cunningham, Richard, Jia, Siyang, Purohit, Krishna, Salem, Omar, Hui, Ning Sze, Lin, Yue, Carragher, Neil O., Hansen, Carsten Gram

المساهمون: Worldwide Cancer Research, Wellcome Trust

المصدر: Clinical and Translational Medicine ; volume 13, issue 2 ; ISSN 2001-1326 2001-1326

الإتاحة: https://doi.org/10.1002/ctm2.1190Test

المؤلفون: Li, Xue-Feng, Selli, Cigdem, Zhou, Han-Lin, Cao, Jian, Wu, Shuiqing, Ma, Ruo-Yu, Lu, Ye, Zhang, Cheng-Bin, Xun, Bijie, Lam, Alyson D., Pang, Xiao-Cong, Fernando, Anu, Zhang, Zeda, Unciti-Broceta, Asier, Carragher, Neil O., Ramachandran, Prakash, Henderson, Neil C., Sun, Ling-Ling, Hu, Hai-Yan, Li, Gui-Bo, Sawyers, Charles, Qian, Bin-Zhi

المساهمون: European Research Council, Fellowship of China Postdoctoral Science Foundation, International Postdoctoral Exchange Fellowship Program, Natural Science Foundation of China, Wellcome Trust

المصدر: Journal of Experimental Medicine ; volume 220, issue 4 ; ISSN 0022-1007 1540-9538

الإتاحة: https://doi.org/10.1084/jem.20221007Test