Amyloid Fibril Formation of Arctic Amyloid-β 1–42 Peptide is Efficiently Inhibited by the BRICHOS Domain
| العنوان: | Amyloid Fibril Formation of Arctic Amyloid-β 1–42 Peptide is Efficiently Inhibited by the BRICHOS Domain |
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| المؤلفون: | Xueying Zhong, Rakesh Kumar, Yu Wang, Henrik Biverstål, Caroline Ingeborg Jegerschöld, Philip J B Koeck, Jan Johansson, Axel Abelein, Gefei Chen |
| المصدر: | ACS Chemical Biology. 17:2201-2211 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Amyloid, Amyloid beta-Peptides, Alzheimer Disease, Humans, Molecular Medicine, General Medicine, Peptides, Receptors for Activated C Kinase, Biochemistry, Peptide Fragments, Molecular Chaperones |
| الوصف: | Amyloid-β peptide (Aβ) aggregation is one of the hallmarks of Alzheimer's disease (AD). Mutations in Aβ are associated with early onset familial AD, and the Arctic mutant E22G (Aβ |
| تدمد: | 1554-8937 1554-8929 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea6b97e29aeb3e7731e0dd05e1d895bTest https://doi.org/10.1021/acschembio.2c00344Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0ea6b97e29aeb3e7731e0dd05e1d895b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15548937 15548929 |
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