المؤلفون: Canul-Tec, Juan, C, Kumar, Anand, Dhenin, Jonathan, Assal, Redda, Legrand, Pierre, Rey, Martial, Jean-Pierre, Chamot-Rooke, Julia, Reyes, Nicolas

المساهمون: Mécanismes des Protéines Membranaires - Membrane Protein Mechanisms, Institut Pasteur Paris (IP), Institut Européen de Chimie et de Biologie, Microbiologie Fondamentale et Pathogénicité (MFP), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), Spectrométrie de Masse pour la Biologie – Mass Spectrometry for Biology (UTechS MSBio), Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), The work was funded by the European Research Council (ERC grant 309657 to NR). JCC-T was partly supported by a Pasteur-Roux Postdoctoral Fellowship. Further support from Institut Pasteur, INCA 2017-44 Grant, CACSICE grant (ANR-11-EQPX-008), and CNRS UMR3528 to NR and JC-R is acknowledged., The authors thank Ahmed Haouz and the staff at the crystallogenesis core facility of the Institut Pasteur for assistance with crystallization screens and staff at Synchrotron Soleil and the European Synchrotron Radiation Facility for assistance with data collection. The IECB cryoEM imaging facility is acknowledged for support in cryo-EM sample screening and initial data acquisition, the EMBL-Heildelberg Cryo-Electron Microscopy Service Platform for support in cryoEM data collection., ANR-11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), European Project: 309657,EC:FP7:ERC,ERC-2012-StG_20111109,HEAATS(2012)

المصدر: ISSN: 0261-4189.

مصطلحات موضوعية: cryo-EM, neurotransmitter transport, permeation and transport, solute carrier, X-ray crystallography, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34747040; info:eu-repo/grantAgreement/EC/FP7/309657/EU/Molecular bases of human excitatory neurotransmitter transport across the plasma membrane/HEAATS; pasteur-03795591; https://pasteur.hal.science/pasteur-03795591Test; https://pasteur.hal.science/pasteur-03795591/documentTest; https://pasteur.hal.science/pasteur-03795591/file/Canul_et_al_2021_HAL_comp.pdfTest; PUBMED: 34747040; PUBMEDCENTRAL: PMC8724772

الإتاحة: https://doi.org/10.15252/embj.2021108341Test
https://pasteur.hal.science/pasteur-03795591Test
https://pasteur.hal.science/pasteur-03795591/documentTest
https://pasteur.hal.science/pasteur-03795591/file/Canul_et_al_2021_HAL_comp.pdfTest

المؤلفون: Khare, Shashank, Villalba, Miryam I., Canul-Tec, Juan C., Cajiao, Arantza Balsebre, Kumar, Anand, Backovic, Marija, Rey, Felix A., Pardon, Els, Steyaert, Jan, Perez, Camilo, Reyes, Nicolas

المصدر: Nature Structural and Molecular Biology; 20240101, Issue: Preprints p1-9, 9p

المؤلفون: CIRRI, Erica, BRIER, Sebastien, ASSAL, Reda, CANUL TEC, Juan Carlos, CHAMOT ROOKE, Julia, REYES, Nicolas

مصطلحات موضوعية: Amino Acid Sequence, Amino Acid Transport System X-AG, Consensus Sequence, Deuterium Exchange Measurement, Excitatory Amino Acid Transporter 1, Humans, Kinetics, Models, Molecular, Mutant Proteins, Neurotransmitter Agents, Protein Stability, Protein Subunits, Protein Unfolding, Temperature, Sciences du Vivant [q-bio]/Microbiologie et Parasitologie

العلاقة: https://oskar-bordeaux.fr/handle/20.500.12278/186021Test

الإتاحة: https://doi.org/20.500.12278/186021Test
https://doi.org/10.7554/eLife.40110Test
https://oskar-bordeaux.fr/handle/20.500.12278/186021Test
https://hdl.handle.net/20.500.12278/186021Test

المؤلفون: Canul-Tec, Juan, Assal, Reda, Cirri, Erica, Legrand, Pierre, Brier, Sébastien, Chamot-Rooke, Julia, Reyes, Nicolas

المساهمون: Mécanismes moléculaires du transport membranaire - Molecular mechanisms of membrane transport, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Spectrométrie de Masse pour la Biologie – Mass Spectrometry for Biology (UTechS MSBio), Institut Pasteur Paris (IP)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), The work was funded by the ERC Starting grant 309657 (N.R.). Further support from G5 Institut Pasteur funds (N.R.), CACSICE grant (ANR-11-EQPX-008), and CNRS UMR3528 (N.R., J.C.-R.) is acknowledged., We thank O. Boudker for comments on the manuscript and discussion on consensus mutagenesis, P. V. Krasteva for comments on the manuscript, A. Haouz and the staff at the crystallogenesis core facility of the Institut Pasteur for assistance with crystallization screens, Staff at Synchrotron SOLEIL and the European Synchrotron Radiation Facility for assistance with data collection, D. O’Brien for discussion of HDX results., ANR-11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), European Project: 309657,EC:FP7:ERC,ERC-2012-StG_20111109,HEAATS(2012)

المصدر: ISSN: 0028-0836.

مصطلحات موضوعية: Membrane proteins, Molecular neuroscience, Permeation and transport, MESH: Allosteric Regulation, MESH: Allosteric Site, MESH: Crystallization, MESH: Crystallography, X-Ray, MESH: Deuterium Exchange Measurement, MESH: Excitatory Amino Acid Transporter 1, MESH: Humans, MESH: Mass Spectrometry, MESH: Models, Molecular, MESH: Protein Domains, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28424515; info:eu-repo/grantAgreement/EC/FP7/309657/EU/Molecular bases of human excitatory neurotransmitter transport across the plasma membrane/HEAATS; pasteur-01655604; https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604Test; https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/documentTest; https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/fileTest/Canul-Tech-etal_nature_accepted_HAL.pdf; PUBMED: 28424515; PUBMEDCENTRAL: PMC5410168

الإتاحة: https://doi.org/10.1038/nature22064Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/documentTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/fileTest/Canul-Tech-etal_nature_accepted_HAL.pdf

المؤلفون: Reyes, Nicolas, Canul Tec, Juan Carlos, Assal, Reda, Cirri, Erica, Legrand, Pierre, Brier, Sebastien, Chamot-Rooke, Julia

المصدر: Biophysical Journal ; volume 112, issue 3, page 13a ; ISSN 0006-3495

مصطلحات موضوعية: Biophysics

الإتاحة: https://doi.org/10.1016/j.bpj.2016.11.101Test
https://api.elsevier.com/content/article/PII:S0006349516311316?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0006349516311316?httpAccept=text/plainTest

المؤلفون: Villalba, Miryam I., Canul-Tec, Juan C., Luna-Martínez, Oscar D., Sánchez-Alcalá, Rosalba, Olamendi-Portugal, Timoteo, Rudiño-Piñera, Enrique, Rojas, Sonia, Sánchez-López, Rosana, Fernández-Velasco, Daniel A., Becerril, Baltazar

المساهمون: National Institutes of Health

المصدر: Journal of Biological Chemistry ; volume 290, issue 5, page 2577-2592 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.m114.629550Test
https://api.elsevier.com/content/article/PII:S0021925820492361?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925820492361?httpAccept=text/plainTest

المؤلفون: Canul‐Tec, Juan C, Kumar, Anand, Dhenin, Jonathan, Assal, Reda, Legrand, Pierre, Rey, Martial, Chamot‐Rooke, Julia, Reyes, Nicolas

المساهمون: FP7 Ideas: European Research Council, Institut National Du Cancer, Agence Nationale de la Recherche, Institut Pasteur, Centre National de la Recherche Scientifique

المصدر: The EMBO Journal ; volume 41, issue 1 ; ISSN 0261-4189 1460-2075

مصطلحات موضوعية: General Immunology and Microbiology, General Biochemistry, Genetics and Molecular Biology, Molecular Biology, General Neuroscience

الإتاحة: https://doi.org/10.15252/embj.2021108341Test

المؤلفون: Canul-Tec, Juan Carlos, Riaño-Umbarila, Lidia, Rudiño-Piñera, Enrique, Becerril, Baltazar, Possani, Lourival D., Torres-Larios, Alfredo

المصدر: Journal of Biological Chemistry ; volume 286, issue 23, page 20892-20900 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.m111.238410Test
https://api.elsevier.com/content/article/PII:S0021925819491527?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925819491527?httpAccept=text/plainTest

المؤلفون: Villalba, Miryam I., Canul-Tec, Juan C., Luna-Martínez, Oscar D., Sánchez-Alcalá, Rosalba, Olamendi-Portugal, Timoteo, Rudiño-Piñera, Enrique, Rojas, Sonia, Sánchez-López, Rosana, Fernández-Velasco, Daniel A., Becerril, Baltazar

مصطلحات موضوعية: 59 BASIC BIOLOGICAL SCIENCES, 60 APPLIED LIFE SCIENCES

وصف الملف: application/pdf

العلاقة: http://www.osti.gov/servlets/purl/1349050Test; https://www.osti.gov/biblio/1349050Test; https://doi.org/10.1074/jbc.m114.629550Test

الإتاحة: https://doi.org/10.1074/jbc.m114.629550Test
http://www.osti.gov/servlets/purl/1349050Test
https://www.osti.gov/biblio/1349050Test

المؤلفون: Cirri, Erica, Brier, Sébastien, Assal, Reda, Canul-Tec, Juan Carlos, Chamot-Rooke, Julia, Reyes, Nicolas

الإتاحة: https://doi.org/10.7554/elife.40110.024Test