المؤلفون: Yaron, Tomer M, Heaton, Brook E, Levy, Tyler M, Johnson, Jared L, Jordan, Tristan X, Cohen, Benjamin M, Kerelsky, Alexander, Lin, Ting-Yu, Liberatore, Katarina M, Bulaon, Danielle K, Van Nest, Samantha J, Koundouros, Nikos, Kastenhuber, Edward R, Mercadante, Marisa N, Shobana-Ganesh, Kripa, He, Long, Schwartz, Robert E, Chen, Shuibing, Weinstein, Harel, Elemento, Olivier, Piskounova, Elena, Nilsson-Payant, Benjamin E, Lee, Gina, Trimarco, Joseph D, Burke, Kaitlyn N, Hamele, Cait E, Chaparian, Ryan R, Harding, Alfred T, Tata, Aleksandra, Zhu, Xinyu, Tata, Purushothama Rao, Smith, Clare M, Possemato, Anthony P, Tkachev, Sasha L, Hornbeck, Peter V, Beausoleil, Sean A, Anand, Shankara K, Aguet, François, Getz, Gad, Davidson, Andrew D, Heesom, Kate, Kavanagh-Williamson, Maia, Matthews, David A, tenOever, Benjamin R, Cantley, Lewis C, Blenis, John, Heaton, Nicholas S

المصدر: Science Signaling. 15(757)

مصطلحات موضوعية: Pneumonia & Influenza, Prevention, Immunization, Biotechnology, Vaccine Related, Lung, Emerging Infectious Diseases, Infectious Diseases, Infection, Good Health and Well Being, Animals, Humans, SARS-CoV-2, Phosphorylation, COVID-19, Glycogen Synthase Kinase 3, Virus Replication, Nucleocapsid Proteins, Nucleocapsid, Serine, Threonine, Mammals, Protein Serine-Threonine Kinases, Biochemistry and Cell Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/44d513ncTest

المؤلفون: Ludwig, David S, Aronne, Louis J, Astrup, Arne, de Cabo, Rafael, Cantley, Lewis C, Friedman, Mark I, Heymsfield, Steven B, Johnson, James D, King, Janet C, Krauss, Ronald M, Lieberman, Daniel E, Taubes, Gary, Volek, Jeff S, Westman, Eric C, Willett, Walter C, Yancy, William S, Ebbeling, Cara B

المصدر: American Journal of Clinical Nutrition. 114(6)

مصطلحات موضوعية: Prevention, Obesity, Nutrition, Cancer, Cardiovascular, Oral and gastrointestinal, Metabolic and endocrine, Stroke, Affordable and Clean Energy, Carbohydrates, Dietary Carbohydrates, Dietary Fats, Energy Intake, Energy Metabolism, Humans, Insulin, Pandemics, obesity, weight loss, dietary carbohydrate, energy balance, macronutrients, endocrinology, insulin, glucagon, incretins, scholarly discourse, Engineering, Medical and Health Sciences, Nutrition & Dietetics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7wm5x0gjTest

المؤلفون: Rogava, Meri, Aprati, Tyler J, Chi, Wei-Yu, Melms, Johannes C, Hug, Clemens, Davis, Stephanie H, Earlie, Ethan M, Chung, Charlie, Deshmukh, Sachin K, Wu, Sharon, Sledge, George, Tang, Stephen, Ho, Patricia, Amin, Amit Dipak, Caprio, Lindsay, Gurjao, Carino, Tagore, Somnath, Ngo, Bryan, Lee, Michael J, Zanetti, Giorgia, Wang, Yiping, Chen, Sean, Ge, William, Melo, Luiza Martins Nascentes, Allies, Gabriele, Rösler, Jonas, Gibney, Goeffrey T, Schmitz, Oliver J, Sykes, Megan, Creusot, Rémi J, Tüting, Thomas, Schadendorf, Dirk, Röcken, Martin, Eigentler, Thomas K, Molotkov, Andrei, Mintz, Akiva, Bakhoum, Samuel F, Beyaz, Semir, Cantley, Lewis C, Sorger, Peter K, Meckelmann, Sven W, Tasdogan, Alpaslan, Liu, David, Laughney, Ashley M, Izar, Benjamin

مصطلحات موضوعية: cancer, diseases & disorders, Investigative techniques and equipment, CRISPR-Cas9, liver, metastasis, organs types and functions, organs, tissues, organelles, cell types and functions

وصف الملف: application/pdf

العلاقة: https://repository.cshl.edu/id/eprint/41428/1/s43018-023-00704-x.pdfTest; Rogava, Meri, Aprati, Tyler J, Chi, Wei-Yu, Melms, Johannes C, Hug, Clemens, Davis, Stephanie H, Earlie, Ethan M, Chung, Charlie, Deshmukh, Sachin K, Wu, Sharon, Sledge, George, Tang, Stephen, Ho, Patricia, Amin, Amit Dipak, Caprio, Lindsay, Gurjao, Carino, Tagore, Somnath, Ngo, Bryan, Lee, Michael J, Zanetti, Giorgia, Wang, Yiping, Chen, Sean, Ge, William, Melo, Luiza Martins Nascentes, Allies, Gabriele, Rösler, Jonas, Gibney, Goeffrey T, Schmitz, Oliver J, Sykes, Megan, Creusot, Rémi J, Tüting, Thomas, Schadendorf, Dirk, Röcken, Martin, Eigentler, Thomas K, Molotkov, Andrei, Mintz, Akiva, Bakhoum, Samuel F, Beyaz, Semir, Cantley, Lewis C, Sorger, Peter K, Meckelmann, Sven W, Tasdogan, Alpaslan, Liu, David, Laughney, Ashley M, Izar, Benjamin (January 2024) Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature Cancer. ISSN 2662-1347 (Public Dataset)

الإتاحة: https://doi.org/10.1038/s43018-023-00704-xTest
https://repository.cshl.edu/id/eprint/41428Test/
https://repository.cshl.edu/id/eprint/41428/1/s43018-023-00704-x.pdfTest
https://www.ncbi.nlm.nih.gov/pubmed/38286827Test

المؤلفون: Zheng, Yuxiang, Lin, Ting-Yu, Lee, Gina, Paddock, Marcia N, Momb, Jessica, Cheng, Zhe, Li, Qian, Fei, Dennis L, Stein, Benjamin D, Ramsamooj, Shivan, Zhang, Guoan, Blenis, John, Cantley, Lewis C

المصدر: Cell. 175(6)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Nutrition, Complementary and Integrative Health, Cancer, Carbon, Cytosol, Formates, HCT116 Cells, HeLa Cells, Humans, MCF-7 Cells, Methotrexate, Mitochondria, Mitochondrial Proteins, Neoplasm Proteins, Neoplasms, Tetrahydrofolate Dehydrogenase, Tetrahydrofolates, Hela Cells, folate, formate, metabolism, methotrexate, mitochondria, one-carbon, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6bc6x1f8Test

المؤلفون: Triscott, Joanna, Reist, Matthias, Küng, Lukas, Moselle, Francielle C, Lehner, Marika, Gallon, John, Ravi, Archna, Arora, Gurpreet K, De Brot, Simone, Lundquist, Mark, Gallart-Ayala, Hector, Ivanisevic, Julijana, Piscuoglio, Salvatore, Cantley, Lewis C, Emerling, Brooke M, Rubin, Mark A

المصدر: Triscott, Joanna; Reist, Matthias; Küng, Lukas; Moselle, Francielle C; Lehner, Marika; Gallon, John; Ravi, Archna; Arora, Gurpreet K; De Brot, Simone; Lundquist, Mark; Gallart-Ayala, Hector; Ivanisevic, Julijana; Piscuoglio, Salvatore; Cantley, Lewis C; Emerling, Brooke M; Rubin, Mark A (2023). PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition. Science Advances, 9(5), eade8641. American Association for the Advancement of Science 10.1126/sciadv.ade8641

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

العلاقة: https://boris.unibe.ch/178285Test/

الإتاحة: https://doi.org/10.1126/sciadv.ade8641Test
https://boris.unibe.ch/178285/1/sciadv.ade8641.pdfTest
https://boris.unibe.ch/178285Test/

المؤلفون: Davidson, Shawn M, Schmidt, Daniel R, Heyman, Julia E, O'Brien, James P, Liu, Amy C, Israelsen, William J, Dayton, Talya L, Sehgal, Raghav, Bronson, Roderick T, Freinkman, Elizaveta, Mak, Howard H, Fanelli, Giuseppe Nicolò, Malstrom, Scott, Bellinger, Gary, Carracedo, Arkaitz, Pandolfi, Pier Paolo, Courtney, Kevin D, Jha, Abhishek, DePinho, Ronald A, Horner, James W, Thomas, Craig J, Cantley, Lewis C, Loda, Massimo, Vander Heiden, Matthew G

المساهمون: Massachusetts Institute of Technology. Department of Biology

المصدر: AACR Journals

وصف الملف: application/pdf

العلاقة: Cancer Research; https://hdl.handle.net/1721.1/147020Test; Davidson, Shawn M, Schmidt, Daniel R, Heyman, Julia E, O'Brien, James P, Liu, Amy C et al. 2022. "Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma." Cancer Research, 82 (13).

الإتاحة: https://hdl.handle.net/1721.1/147020Test

المؤلفون: Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Torres Robles, Jaylissa, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.

المساهمون: Biochemistry and Molecular Biology, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Kinases, Cellular signalling networks, Bioinformatics, Phosphorylation

وصف الملف: application/pdf

العلاقة: Nature; Johnson JL, Yaron TM, Huntsman EM, et al. An atlas of substrate specificities for the human serine/threonine kinome. Nature. 2023;613(7945):759-766. doi:10.1038/s41586-022-05575-3; https://hdl.handle.net/1805/36481Test

الإتاحة: https://doi.org/10.1038/s41586-022-05575-3Test
https://hdl.handle.net/1805/36481Test

المؤلفون: Jbara, Amina, Lin, Kuan-Ting, Stossel, Chani, Siegfried, Zahava, Shqerat, Haya, Amar-Schwartz, Adi, Elyada, Ela, Mogilevsky, Maxim, Raitses-Gurevich, Maria, Johnson, Jared L., Yaron, Tomer M., Ovadia, Ofek, Jang, Gun Ho, Danan-Gotthold, Miri, Cantley, Lewis C., Levanon, Erez Y., Gallinger, Steven, Krainer, Adrian R., Golan, Talia, Karni, Rotem

المصدر: Nature ; volume 617, issue 7959, page 147-153 ; ISSN 0028-0836 1476-4687

مصطلحات موضوعية: Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41586-023-05820-3Test
https://www.nature.com/articles/s41586-023-05820-3.pdfTest
https://www.nature.com/articles/s41586-023-05820-3Test

المؤلفون: Paul, Swagatika, Sarraf, Shireen A., Nam, Ki Hong, Zavar, Leila, DeFoor, Nicole, Biswas, Sahitya Ranjan, Fritsch, Lauren E., Yaron, Tomer M., Johnson, Jared L., Huntsman, Emily M., Cantley, Lewis C., Ordureau, Alban, Pickrell, Alicia M.

المساهمون: National Institutes of Health

المصدر: Journal of Cell Biology ; volume 223, issue 2 ; ISSN 0021-9525 1540-8140

الإتاحة: https://doi.org/10.1083/jcb.202303082Test

المؤلفون: Lin, Ting-Yu, Ramsamooj, Shakti, Perrier, Tiffany, Liberatore, Katarina, Lantier, Louise, Vasan, Neil, Karukurichi, Kannan, Hwang, Seo-Kyoung, Kesicki, Edward A., Kastenhuber, Edward R., Wiederhold, Thorsten, Yaron, Tomer M., Huntsman, Emily M., Zhu, Mengmeng, Ma, Yilun, Paddock, Marcia N., Zhang, Guoan, Hopkins, Benjamin D., McGuinness, Owen, Schwartz, Robert E., Ersoy, Baran A., Cantley, Lewis C., Johnson, Jared L., Goncalves, Marcus D.

المصدر: Cell Reports ; volume 42, issue 12, page 113535 ; ISSN 2211-1247

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.celrep.2023.113535Test
https://api.elsevier.com/content/article/PII:S2211124723015474?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2211124723015474?httpAccept=text/plainTest