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1دورية أكاديمية
المؤلفون: Anuj Khandelwal, Caitlin N. Kent, Maurie Balch, Shuxia Peng, Sanket J. Mishra, Junpeng Deng, Victor W. Day, Weiya Liu, Chitra Subramanian, Mark Cohen, Jeffery M. Holzbeierlein, Robert Matts, Brian S. J. Blagg
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
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المؤلفون: Samantha J. McClenahan, Caitlin N. Kent, Sujay V. Kharade, Elena Isaeva, Jade C. Williams, Changho Han, Andrew Terker, Robert Gresham, Roman M. Lazarenko, Emily L. Days, Ian M. Romaine, Joshua A. Bauer, Olivier Boutaud, Gary A. Sulikowski, Raymond Harris, C. David Weaver, Alexander Staruschenko, Craig W. Lindsley, Jerod S. Denton
المصدر: Mol Pharmacol
مصطلحات موضوعية: Pharmacology, Mice, Potassium, Potassium Channel Blockers, Animals, Molecular Medicine, Articles, Potassium Channels, Inwardly Rectifying, Gene Library, High-Throughput Screening Assays
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fbdcbfcd068da9cf2cba3d0be7037fTest
https://doi.org/10.1124/molpharm.121.000464Test -
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المؤلفون: Monimoy Banerjee, Caitlin N. Kent, Penchala Narasimharao Meka, Subhabrata Chaudhury, Brian S. J. Blagg
المصدر: Chemistry
مصطلحات موضوعية: Gene isoform, Combination therapy, biology, Chemistry, Organic Chemistry, Cancer, General Chemistry, Computational biology, medicine.disease, Hsp90, Article, Catalysis, Design synthesis, Neoplasms, Heat shock protein, biology.protein, medicine, Humans, Protein Isoforms, Protein folding, HSP90 Heat-Shock Proteins, Heat shock, Molecular Chaperones, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8c36e98335a0e974b1aa2571c9c0d4Test
https://doi.org/10.1002/chem.202102574Test -
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المؤلفون: Leonard M. Neckers, John Koren, Kristin Beebe, Vitumbiko Munthali, Jeffrey M. Holzbeierlein, Brian S. J. Blagg, Weiya Liu, Sanket J. Mishra, John A. Taylor, Monimoy Banerjee, Caitlin N. Kent
المصدر: Journal of Medicinal Chemistry. 64:1545-1557
مصطلحات موضوعية: Gene isoform, 0303 health sciences, biology, Chemistry, Cancer, Small Molecule Libraries, medicine.disease, 01 natural sciences, Hsp90, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Heat shock protein, Drug Discovery, polycyclic compounds, Cancer research, medicine, biology.protein, Molecular Medicine, Structure–activity relationship, Gene silencing, Protein folding, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ae713e75838f258bcdb77b9f5d0cb66cTest
https://doi.org/10.1021/acs.jmedchem.0c01700Test -
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المؤلفون: Sanket J, Mishra, Weiya, Liu, Kristin, Beebe, Monimoy, Banerjee, Caitlin N, Kent, Vitumbiko, Munthali, John, Koren, John A, Taylor, Leonard M, Neckers, Jeffrey, Holzbeierlein, Brian S J, Blagg
المصدر: J Med Chem
مصطلحات موضوعية: Models, Molecular, Protein Folding, Molecular Conformation, Antineoplastic Agents, Heterocyclic Compounds, 4 or More Rings, Article, Substrate Specificity, Small Molecule Libraries, Structure-Activity Relationship, Urinary Bladder Neoplasms, Cell Line, Tumor, Neoplasms, polycyclic compounds, Humans, Gene Silencing, HSP90 Heat-Shock Proteins, Cell Proliferation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::fea484f03b8f837f82dd59c679412e46Test
https://pubmed.ncbi.nlm.nih.gov/33428418Test -
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المؤلفون: Caitlin N, Kent, Mark G, Fulton, Kaylee J, Stillwell, Jonathan W, Dickerson, Matthew T, Loch, Alice L, Rodriguez, Anna L, Blobaum, Olivier, Boutaud, Jerri L, Rook, Colleen M, Niswender, P Jeffrey, Conn, Craig W, Lindsley
المصدر: Bioorganicmedicinal chemistry letters. 37
مصطلحات موضوعية: Catalepsy, Disease Models, Animal, Mice, Structure-Activity Relationship, Neuroprotective Agents, Allosteric Regulation, Dose-Response Relationship, Drug, Molecular Structure, Drug Discovery, Animals, Haloperidol, Parkinson Disease, Receptors, Metabotropic Glutamate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::aa0e4acb766ebacc10e8996ddcf9fb14Test
https://pubmed.ncbi.nlm.nih.gov/33556572Test -
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المساهمون: Giustiniano, M., Gruber, C. W., Kent, C. N., Trippier, P. C.
مصطلحات موضوعية: World Wide Web, Pharmaceutical Preparations, Chemistry, Chemistry, Pharmaceutical, Drug Discovery, MEDLINE, Humans, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3014a4fdd90912594e4ffc0bd52dd0fTest
https://hdl.handle.net/11588/907805Test -
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المؤلفون: Chitra Subramanian, Robert L. Matts, Brian S. J. Blagg, Anuj Khandelwal, Weiya Liu, Jeffery M. Holzbeierlein, Junpeng Deng, Mark S. Cohen, Victor W. Day, Sanket J. Mishra, Caitlin N. Kent, Maurie Balch, Shuxia Peng
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Gene isoform, Science, Drug Evaluation, Preclinical, General Physics and Astronomy, Antineoplastic Agents, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, Heat shock protein, polycyclic compounds, medicine, Humans, Protein Isoforms, Structure–activity relationship, HSP90 Heat-Shock Proteins, Heat shock, lcsh:Science, Multidisciplinary, biology, Chemistry, HEK 293 cells, Cancer, Hydrogen Bonding, General Chemistry, medicine.disease, Hsp90, 3. Good health, Cell biology, HEK293 Cells, 030104 developmental biology, Drug Design, biology.protein, Protein folding, lcsh:Q
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca0d3fd460c06cb7b268c988c06edc1Test
http://link.springer.com/article/10.1038/s41467-017-02013-1Test -
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المؤلفون: Brian S. J. Blagg, Katherine M. Byrd, Caitlin N. Kent
المصدر: ChemMedChem. 12:2022-2029
مصطلحات موضوعية: Stereochemistry, Triazole, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Amide, Stilbenes, Drug Discovery, medicine, Side chain, Humans, Molecule, Structure–activity relationship, HSP90 Heat-Shock Proteins, General Pharmacology, Toxicology and Pharmaceutics, Novobiocin, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, Hsp90, 0104 chemical sciences, chemistry, biology.protein, Molecular Medicine, Piperidine, Drug Screening Assays, Antitumor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe51d71c54ecf5716dd75fd0a5317418Test
https://doi.org/10.1002/cmdc.201700630Test -
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المؤلفون: Kaylee J. Stillwell, Jonathan W. Dickerson, Matthew T. Loch, Craig W. Lindsley, Mark G. Fulton, Olivier Boutaud, P. Jeffrey Conn, Colleen M. Niswender, Caitlin N. Kent, Alice L. Rodriguez, Jerri L. Rook, Anna L. Blobaum
المصدر: Bioorganic & Medicinal Chemistry Letters. 37:127838
مصطلحات موضوعية: 010405 organic chemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Catalepsy, medicine.disease, 01 natural sciences, Biochemistry, 0104 chemical sciences, Cns penetration, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Molecular Medicine, Penetrant (biochemical), Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8982a8ca4fb9fbb1b11c0095cf87e8fbTest
https://doi.org/10.1016/j.bmcl.2021.127838Test