المؤلفون: Cai, Huiqiang, Zhang, Bin, Ahrenfeldt, Johanne, Joseph, Justin V., Riedel, Maria, Gao, Zongliang, Thomsen, Sofie K., Christensen, Ditte S., Bak, Rasmus O., Hager, Henrik, Vendelbo, Mikkel H., Gao, Xin, Birkbak, Nicolai, Thomsen, Martin K.

المصدر: Cai , H , Zhang , B , Ahrenfeldt , J , Joseph , J V , Riedel , M , Gao , Z , Thomsen , S K , Christensen , D S , Bak , R O , Hager , H , Vendelbo , M H , Gao , X , Birkbak , N & Thomsen , M K 2024 , ' CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression ' , Nature Communications , vol. 15 , no. 1 , 2088 . https://doi.org/10.1038/s41467-024-46370-0Test , https://doi.org/10.1038/s41467-024-46370-0Test

مصطلحات موضوعية: Male, Humans, Animals, Mice, CRISPR-Cas Systems/genetics, Prostatic Neoplasms/genetics, Transcriptome, Multigene Family

العلاقة: https://pure.au.dk/portal/en/publications/48136e79-1998-4e13-986b-0c921f9b3f18Test

الإتاحة: https://doi.org/10.1038/s41467-024-46370-0Test
https://pure.au.dk/portal/en/publications/48136e79-1998-4e13-986b-0c921f9b3f18Test
http://www.scopus.com/inward/record.url?scp=85187165808&partnerID=8YFLogxKTest

المؤلفون: Joseph, Justin V., Blaavand, Mathilde S., Cai, Huiqiang, Vernejoul, Fabienne, Knopper, Rasmus W., Lindhardt, Thomas B., Skipper, Kristian A., Axelgaard, Esben, Reinert, Line, Mikkelsen, Jacob G., Borghammer, Per, Degn, Søren E., Perouzel, Eric, Hager, Henrik, Hansen, Brian, Kalucka, Joanna M., Vendelbo, Mikkel, Paludan, Søren R., Thomsen, Martin K.

المصدر: Joseph , J V , Blaavand , M S , Cai , H , Vernejoul , F , Knopper , R W , Lindhardt , T B , Skipper , K A , Axelgaard , E , Reinert , L , Mikkelsen , J G , Borghammer , P , Degn , S E , Perouzel , E , Hager , H , Hansen , B , Kalucka , J M , Vendelbo , M , Paludan , S R & Thomsen , M K 2023 , ' STING activation counters glioblastoma by vascular alteration and immune surveillance ' ....

مصطلحات موضوعية: CRISPR, GBM, Immunotherapy, Mouse models, STING agonist, Immunotherapy/methods, Humans, Tumor Microenvironment, Brain Neoplasms/metabolism, Glioblastoma/metabolism

العلاقة: https://pure.au.dk/portal/en/publications/399cfb9e-28a8-4ab3-9b72-7a0baff61e6dTest

الإتاحة: https://doi.org/10.1016/j.canlet.2023.216480Test
https://pure.au.dk/portal/en/publications/399cfb9e-28a8-4ab3-9b72-7a0baff61e6dTest
http://www.scopus.com/inward/record.url?scp=85176215680&partnerID=8YFLogxKTest

المؤلفون: Cai, Xiaopeng, Deng, Jingwen, Zhou, Xiaohu, Wang, Kaiyue, Cai, Huiqiang, Yan, Yingcai, Jiang, Jun, Yang, Jia, Gu, Jin, Zhang, Yuan, Ding, Yuan, Sun, Qiang, Wang, Weilin

المصدر: Int J Surg ; ISSN:1743-9159

العلاقة: https://doi.org/10.1097/JS9.0000000000001893Test; https://pubmed.ncbi.nlm.nih.gov/38935114Test

الإتاحة: https://doi.org/10.1097/JS9.0000000000001893Test
https://pubmed.ncbi.nlm.nih.gov/38935114Test

المؤلفون: Gao, Zongliang, Ravendran, Sujan, Mikkelsen, Nanna S., Haldrup, Jakob, Cai, Huiqiang, Ding, Xiangning, Paludan, Søren R., Thomsen, Martin K., Mikkelsen, Jacob Giehm, Bak, Rasmus O.

المصدر: Gao , Z , Ravendran , S , Mikkelsen , N S , Haldrup , J , Cai , H , Ding , X , Paludan , S R , Thomsen , M K , Mikkelsen , J G & Bak , R O 2022 , ' A truncated reverse transcriptase enhances prime editing by split AAV vectors ' , Molecular Therapy , vol. 30 , no. 9 , pp. 2942-2951 . https://doi.org/10.1016/j.ymthe.2022.07.001Test

مصطلحات موضوعية: AAV vectors, CRISPR-Cas9, gene editing, gene therapy, in vivo delivery, PASTE, prime editing, reverse transcriptase, Dependovirus/genetics, Animals, CRISPR-Cas Systems, Genetic Vectors/genetics, Proprotein Convertase 9/genetics, Mice, RNA, Guide, Kinetoplastida/genetics, RNA-Directed DNA Polymerase/genetics

العلاقة: https://pure.au.dk/portal/en/publications/f8e75b2d-a57b-496a-b465-f74b4080a2dcTest

الإتاحة: https://doi.org/10.1016/j.ymthe.2022.07.001Test
https://pure.au.dk/portal/en/publications/f8e75b2d-a57b-496a-b465-f74b4080a2dcTest
http://www.scopus.com/inward/record.url?scp=85134827831&partnerID=8YFLogxKTest
https://www.biorxiv.org/content/biorxiv/early/2021/11/05/2021.11.05.467423.full.pdfTest

المؤلفون: Cai, Huiqiang, Agersnap, Simon N., Sjøgren, Amalie, Simonsen, Mikkel K., Blaavand, Mathilde S., Jensen, Ulrikke V., Thomsen, Martin K.

المصدر: Cai , H , Agersnap , S N , Sjøgren , A , Simonsen , M K , Blaavand , M S , Jensen , U V & Thomsen , M K 2022 , ' In Vivo Application of CRISPR/Cas9 Revealed Implication of Foxa1 and Foxp1 in Prostate Cancer Proliferation and Epithelial Plasticity ' , Cancers , vol. 14 , no. 18 , 4381 . https://doi.org/10.3390/cancers14184381Test

مصطلحات موضوعية: cell plasticity, CRISPR, Forkhead box proteins, mouse models, prostate cancer

العلاقة: https://pure.au.dk/portal/da/publications/in-vivo-application-of-crisprcas9-revealed-implication-of-foxa1-and-foxp1-in-prostate-cancer-proliferation-and-epithelial-plasticityTest(d807217b-4e5f-4e88-9fb1-d97a83a45205).html

الإتاحة: https://doi.org/10.3390/cancers14184381Test
https://pure.au.dk/portal/da/publications/in-vivo-application-of-crisprcas9-revealed-implication-of-foxa1-and-foxp1-in-prostate-cancer-proliferation-and-epithelial-plasticityTest(d807217b-4e5f-4e88-9fb1-d97a83a45205).html
http://www.scopus.com/inward/record.url?scp=85138739040&partnerID=8YFLogxKTest

المؤلفون: Berthelsen, Martin Fogtmann, Riedel, Maria, Cai, Huiqiang, Skaarup, Søren H., Alstrup, Aage K.O., Dagnæs-Hansen, Frederik, Luo, Yonglun, Jensen, Uffe B., Hager, Henrik, Liu, Ying, Callesen, Henrik, Vendelbo, Mikkel H., Jakobsen, Jannik E., Thomsen, Martin Kristian

المصدر: Berthelsen , M F , Riedel , M , Cai , H , Skaarup , S H , Alstrup , A K O , Dagnæs-Hansen , F , Luo , Y , Jensen , U B , Hager , H , Liu , Y , Callesen , H , Vendelbo , M H , Jakobsen , J E & Thomsen , M K 2021 , ' The CRISPR/Cas9 Minipig—A Transgenic Minipig to Produce Specific Mutations in Designated Tissues ' , Cancers , vol. 13 , no. 12 , 3024 . https://doi.org/10.3390/cancers13123024Test

مصطلحات موضوعية: Animal models, Cancer, CRISPR, Göttingen minipigs, Handmade cloning, KRAS, Lung cancer, Porcine model, STK11, TP53

العلاقة: https://pure.au.dk/portal/en/publications/f1f00d41-0209-4a56-92ce-a2bd8dd947acTest

الإتاحة: https://doi.org/10.3390/cancers13123024Test
https://pure.au.dk/portal/en/publications/f1f00d41-0209-4a56-92ce-a2bd8dd947acTest
http://www.scopus.com/inward/record.url?scp=85107897352&partnerID=8YFLogxKTest

المؤلفون: Thomsen, Martin Kristian, Cai, Huiqiang, Stoltze, Iben C., Vendelbo, Mikkel, Wagner, Erwin F, Bakiri, Latifa

المصدر: Thomsen , M K , Cai , H , Stoltze , I C , Vendelbo , M , Wagner , E F , Bakiri , L & Thomsen , M K 2021 , ' Targeting AP-1 transcription factors by CRISPR in the prostate ' , OncoTarget , vol. 12 , no. 19 , pp. 1956-1961 . https://doi.org/10.18632/oncotarget.27997Test

مصطلحات موضوعية: AAV, AP-1, CRISPR, Mouse models, Prostate cancer

وصف الملف: application/pdf

العلاقة: https://pure.au.dk/portal/da/publications/targeting-ap1-transcription-factors-by-crispr-in-the-prostateTest(9a113f99-56d0-43bb-ac10-8c89416e4cf3).html

الإتاحة: https://doi.org/10.18632/oncotarget.27997Test
https://pure.au.dk/portal/da/publications/targeting-ap1-transcription-factors-by-crispr-in-the-prostateTest(9a113f99-56d0-43bb-ac10-8c89416e4cf3).html
https://pure.au.dk/ws/files/273858995/oncotarget_v12i19_27997.pdfTest

المؤلفون: Cai, Xiaopeng, Deng, Jingwen, zhou, Jiaming, Cai, Huiqiang, Chen, Zhi

المصدر: Cai , X , Deng , J , zhou , J , Cai , H & Chen , Z 2021 , ' Cyclin-dependent kinase 19 upregulation correlates with an unfavorable prognosis in hepatocellular carcinoma ' , BMC Gastroenterology , vol. 21 , no. 1 , 377 . https://doi.org/10.1186/s12876-021-01962-8Test

مصطلحات موضوعية: Cyclin-dependent kinase 19, Hepatocellular carcinoma, Invasion, Knockdown, Migration, Prognosis, Proliferation

الإتاحة: https://doi.org/10.1186/s12876-021-01962-8Test
https://pure.au.dk/portal/da/publications/cyclindependent-kinase-19-upregulation-correlates-with-an-unfavorable-prognosis-in-hepatocellular-carcinomaTest(3e15c76e-2d8f-49ba-beec-c4dd4267f191).html
http://www.scopus.com/inward/record.url?scp=85117312375&partnerID=8YFLogxKTest

المؤلفون: Riedel, Maria, Berthelsen, Martin F., Cai, Huiqiang, Haldrup, Jakob, Borre, Michael, Paludan, Søren R., Hager, Henrik, Vendelbo, Mikkel H., Wagner, Erwin F., Bakiri, Latifa, Thomsen, Martin K.

المصدر: Riedel , M , Berthelsen , M F , Cai , H , Haldrup , J , Borre , M , Paludan , S R , Hager , H , Vendelbo , M H , Wagner , E F , Bakiri , L & Thomsen , M K 2021 , ' In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun ' , Oncogene , vol. 40 , no. 13 , pp. 2437–2447 . https://doi.org/10.1038/s41388-021-01724-6Test

الإتاحة: https://doi.org/10.1038/s41388-021-01724-6Test
https://pure.au.dk/portal/da/publications/in-vivo-crispr-inactivation-of-fos-promotes-prostate-cancer-progression-by-altering-the-associated-ap1-subunit-junTest(fe74efb7-c179-4613-b88c-42fb511abee6).html
http://www.scopus.com/inward/record.url?scp=85102174512&partnerID=8YFLogxKTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610543/pdf/EMS116956.pdfTest

المؤلفون: Cai, Xiaopeng, Deng, Jingwen, Ming, Qianqian, Cai, Huiqiang, Chen, Zhi

المصدر: Cai , X , Deng , J , Ming , Q , Cai , H & Chen , Z 2020 , ' Chemokine-like factor 1 : A promising therapeutic target in human diseases ' , Experimental Biology and Medicine , vol. 245 , no. 16 , pp. 1518-1528 . https://doi.org/10.1177/1535370220945225Test

مصطلحات موضوعية: chemokine-like factor 1, Chemokines, human diseases, signaling pathways, targeted therapy, tumors, MIGRATION, CELLS, C-TERMINAL PEPTIDE, FOCAL CEREBRAL-ISCHEMIA, C19, CYTOKINE, ARREST, INFLAMMATION, HUMAN CKLF1, MOLECULAR-CLONING, Disease, Signal Transduction, Humans, Molecular Targeted Therapy, Chemotaxis, Chemokines/chemistry, Animals, Models, Biological

العلاقة: https://pure.au.dk/portal/en/publications/3bf8b2e5-55b7-44b0-b8e0-d0018ce7bf8dTest

الإتاحة: https://doi.org/10.1177/1535370220945225Test
https://pure.au.dk/portal/en/publications/3bf8b2e5-55b7-44b0-b8e0-d0018ce7bf8dTest
http://www.scopus.com/inward/record.url?scp=85088599839&partnerID=8YFLogxKTest