المؤلفون: Scott, Robert A, Freitag, Daniel F, Li, Li, Chu, Audrey Y, Surendran, Praveen, Young, Robin, Grarup, Niels, Stancáková, Alena, Chen, Yuning, Varga, Tibor V, Yaghootkar, Hanieh, Luan, Jian’an, Zhao, Jing Hua, Willems, Sara M, Wessel, Jennifer, Wang, Shuai, Maruthur, Nisa, Michailidou, Kyriaki, Pirie, Ailith, van der Lee, Sven J, Gillson, Christopher, Al Olama, Ali Amin, Amouyel, Philippe, Arriola, Larraitz, Arveiler, Dominique, Aviles-Olmos, Iciar, Balkau, Beverley, Barricarte, Aurelio, Barroso, Inês, Garcia, Sara Benlloch, Bis, Joshua C, Blankenberg, Stefan, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Borecki, Ingrid B, Bork-Jensen, Jette, Bowden, Sarah, Caldas, Carlos, Caslake, Muriel, consortium, The CVD50, Cupples, L Adrienne, Cruchaga, Carlos, Czajkowski, Jacek, Hoed, Marcel den, Dunn, Janet A, Earl, Helena M, Ehret, Georg B, Ferrannini, Ele, Ferrieres, Jean, Foltynie, Thomas, Ford, Ian, Forouhi, Nita G, Gianfagna, Francesco, Gonzalez, Carlos, Grioni, Sara, Hiller, Louise, Jansson, Jan-Håkan, Jørgensen, Marit E, Jukema, J Wouter, Kaaks, Rudolf, Kee, Frank, Kerrison, Nicola D, Key, Timothy J, Kontto, Jukka, Kote-Jarai, Zsofia, Kraja, Aldi T, Kuulasmaa, Kari, Kuusisto, Johanna, Linneberg, Allan, Liu, Chunyu, Marenne, Gaëlle, Mohlke, Karen L, Morris, Andrew P, Muir, Kenneth, Müller-Nurasyid, Martina, Munroe, Patricia B, Navarro, Carmen, Nielsen, Sune F, Nilsson, Peter M, Nordestgaard, Børge G, Packard, Chris J, Palli, Domenico, Panico, Salvatore, Peloso, Gina M, Perola, Markus, Peters, Annette, Poole, Christopher J, Quirós, J Ramón, Rolandsson, Olov, Sacerdote, Carlotta, Salomaa, Veikko, Sánchez, María-José, Sattar, Naveed, Sharp, Stephen J, Sims, Rebecca, Slimani, Nadia, Smith, Jennifer A, Thompson, Deborah J, Trompet, Stella

المصدر: Science Translational Medicine. 8(341)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Clinical Research, Diabetes, Human Genome, Cardiovascular, Prevention, Obesity, Genetics, Heart Disease, Heart Disease - Coronary Heart Disease, Clinical Trials and Supportive Activities, Aetiology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 2.1 Biological and endogenous factors, Metabolic and endocrine, Good Health and Well Being, Alleles, Coronary Disease, Diabetes Mellitus, Type 2, Dipeptidyl Peptidase 4, Genotype, Glucagon-Like Peptide-1 Receptor, Humans, Receptor, Cannabinoid, CB2, Receptor, Serotonin, 5-HT2C, Receptors, Somatostatin, Sodium-Glucose Transporter 1, CVD50 consortium, GERAD_EC Consortium, Neurology Working Group of the Cohorts for Heart, Aging Research in Genomic Epidemiology, Alzheimer’s Disease Genetics Consortium, Pancreatic Cancer Cohort Consortium, European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease, EPIC-InterAct, CHARGE consortium, CHD Exome+ Consortium, CARDIOGRAM Exome Consortium, Biological Sciences, Medical and Health Sciences, Medical biotechnology, Biomedical engineering

الوصول الحر: https://escholarship.org/uc/item/0zq8d76wTest

المؤلفون: Scott, RA, Freitag, DF, Li, L, Chu, AY, Surendran, P, Young, R, Grarup, N, Stancáková, A, Chen, Y, Varga, TV, Yaghootkar, H, Luan, J, Zhao, JH, Willems, SM, Wessel, J, Wang, S, Maruthur, N, Michailidou, K, Pirie, A, van der Lee, SJ, Gillson, C, Al Olama, AA, Amouyel, P, Arriola, L, Arveiler, D, Aviles-Olmos, I, Balkau, B, Barricarte, A, Barroso, I, Garcia, SB, Bis, JC, Blankenberg, S, Boehnke, M, Boeing, H, Boerwinkle, E, Borecki, IB, Bork-Jensen, J, Bowden, S, Caldas, C, Caslake, M, CVD50 consortium, Cupples, LA, Cruchaga, C, Czajkowski, J, den Hoed, M, Dunn, JA, Earl, HM, Ehret, GB, Ferrannini, E, Ferrieres, J, Foltynie, T, Ford, I, Forouhi, NG, Gianfagna, F, Gonzalez, C, Grioni, S, Hiller, L, Jansson, J-H, Jørgensen, ME, Jukema, JW, Kaaks, R, Kee, F, Kerrison, ND, Key, TJ, Kontto, J, Kote-Jarai, Z, Kraja, AT, Kuulasmaa, K, Kuusisto, J, Linneberg, A, Liu, C, Marenne, G, Mohlke, KL, Morris, AP, Muir, K, Müller-Nurasyid, M, Munroe, PB, Navarro, C, Nielsen, SF, Nilsson, PM, Nordestgaard, BG, Packard, CJ, Palli, D, Panico, S, Peloso, GM, Perola, M, Peters, A, Poole, CJ, Quirós, JR, Rolandsson, O, Sacerdote, C, Salomaa, V, Sánchez, M-J, Sattar, N, Sharp, SJ, Sims, R, Slimani, N, Smith, JA, Thompson, DJ, Trompet, S, Tumino, R, van der A, DL, van der Schouw, YT, Virtamo, J, Walker, M, Walter, K, GERAD_EC Consortium, Neurology Working Group of the Cohorts for Heart, Aging Research in Genomic Epidemiology (CHARGE), Alzheimer’s Disease Genetics Consortium, Pancreatic Cancer Cohort Consortium, European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD), EPIC-InterAct, Abraham, JE, Amundadottir, LT, Aponte, JL, Butterworth, AS, Dupuis, J, Easton, DF, Eeles, RA, Erdmann, J, Franks, PW, Frayling, TM, Hansen, T, Howson, JMM, Jørgensen, T, Kooner, J, Laakso, M, Langenberg, C, McCarthy, MI, Pankow, JS, Pedersen, O, Riboli, E, Rotter, JI, Saleheen, D, Samani, NJ, Schunkert, H, Vollenweider, P, O'Rahilly, S, CHARGE consortium, CHD Exome+ Consortium, CARDIOGRAM Exome Consortium, Deloukas, P, Danesh, J, Goodarzi, MO, Kathiresan, S, Meigs, JB, Ehm, MG, Wareham, NJ, Waterworth, DM

المساهمون: Kote-Jarai, Zsofia, Eeles, Rosalind

مصطلحات موضوعية: CVD50 consortium, GERAD_EC Consortium, Neurology Working Group of the Cohorts for Heart, Aging Research in Genomic Epidemiology (CHARGE), Alzheimer’s Disease Genetics Consortium, Pancreatic Cancer Cohort Consortium, European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD), EPIC-InterAct, CHARGE consortium, CHD Exome+ Consortium, CARDIOGRAM Exome Consortium, Humans, Coronary Disease, Diabetes Mellitus, Type 2, Obesity, Receptor, Cannabinoid, CB2, Serotonin, 5-HT2C, Receptors, Somatostatin, Genotype, Alleles, Sodium-Glucose Transporter 1, Dipeptidyl Peptidase 4, Glucagon-Like Peptide-1 Receptor

وصف الملف: Print; ?; application/pdf

العلاقة: Science translational medicine, 2016, 8 (341), pp. 341ra76 - ?; https://repository.icr.ac.uk/handle/internal/1463Test

الإتاحة: https://doi.org/10.1126/scitranslmed.aad3744Test
https://repository.icr.ac.uk/handle/internal/1463Test

المؤلفون: Scott, RA, Freitag, DF, Li, L, Chu, AY, Surendran, P, Young, R, Grarup, N, Stancakova, A, Chen, Y, Varga, TV, Yaghootkar, H, Luan, J, Zhao, JH, Willems, SM, Wessel, J, Wang, S, Maruthur, N, Michailidou, K, Pirie, A, Van der Lee, SJ, Gillson, C, Al Olama, AA, Amouyel, P, Arriola, L, Arveiler, D, Aviles-Olmos, I, Balkau, B, Barricarte, A, Barroso, I, Garcia, SB, Bis, JC, Blankenberg, S, Boehnke, M, Boeing, H, Boerwinkle, E, Borecki, IB, Bork-Jensen, J, Bowden, S, Caldas, C, Caslake, M, Cupples, LA, Cruchaga, C, Czajkowski, J, Den Hoed, M, Dunn, JA, Earl, HM, Ehret, GB, Ferrannini, E, Ferrieres, J, Foltynie, T, Ford, I, Forouhi, NG, Gianfagna, F, Gonzalez, C, Grioni, S, Hiller, L, Jansson, J-H, Jorgensen, ME, Jukema, JW, Kaaks, R, Kee, F, Kerrison, ND, Key, TJ, Kontto, J, Kote-Jarai, Z, Kraja, AT, Kuulasmaa, K, Kuusisto, J, Linneberg, A, Liu, C, Marenne, G, Mohlke, KL, Morris, AP, Muir, K, Mueller-Nurasyid, M, Munroe, PB, Navarro, C, Nielsen, SF, Nilsson, PM, Nordestgaard, BG, Packard, CJ, Palli, D, Panico, S, Peloso, GM, Perola, M, Peters, A, Poole, CJ, Quiros, JR, Rolandsson, O, Sacerdote, C, Salomaa, V, Sanchez, M-J, Sattar, N, Sharp, SJ, Sims, R, Slimani, N, Smith, JA, Thompson, DJ, Trompet, S, Tumino, R, Van der A, DL, Van der Schouw, YT, Virtamo, J, Walker, M, Walter, K, Abraham, JE, Amundadottir, LT, Aponte, JL, Butterworth, A, Dupuis, J, Easton, DF, Eeles, RA, Erdmann, J, Franks, PW, Frayling, TM, Hansen, T, Howson, JMM, Jorgensen, T, Kooner, J, Laakso, M, Langenberg, C, McCarthy, MI, Pankow, JS, Pedersen, O, Riboli, E, Rotter, JI, Saleheen, D, Samani, NJ, Schunkert, H, Vollenweider, P, O'Rahilly, S, Deloukas, P, Danesh, J, Goodarzi, MO, Kathiresan, S, Meigs, JB, Ehm, MG, Wareham, NJ, Waterworth, DM

المصدر: 341ra76

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Cell Biology, Medicine, Research & Experimental, Research & Experimental Medicine, GLUCAGON-LIKE PEPTIDE-1, TYPE-2 DIABETES-MELLITUS, PLACEBO-CONTROLLED TRIAL, RECEPTOR AGONIST LIXISENATIDE, ONCE-DAILY LIXISENATIDE, RANDOMIZED CONTROLLED-TRIAL, INCRETIN-BASED THERAPIES, BETA-CELL FUNCTION, BODY-MASS INDEX, DOUBLE-BLIND, CVD50 consortium, GERAD_EC Consortium, Neurology Working Group of the Cohorts for Heart, Aging Research in Genomic Epidemiology (CHARGE), Alzheimer’s Disease Genetics Consortium, Pancreatic Cancer Cohort Consortium, European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD), EPIC-InterAct, CHARGE consortium, CHD Exome+ Consortium, CARDIOGRAM Exome Consortium, 11 Medical And Health Sciences, 06 Biological Sciences

العلاقة: Science Translational Medicine; http://hdl.handle.net/10044/1/38461Test; http://dx.doi.org/10.1126/scitranslmed.aad3744Test

الإتاحة: https://doi.org/10.1126/scitranslmed.aad3744Test
http://hdl.handle.net/10044/1/38461Test

المؤلفون: Nicola D. Kerrison, Carlos González, Mark Walker, Adam S. Butterworth, Martina Müller-Nurasyid, Mark I. McCarthy, Jarmo Virtamo, Nilesh J. Samani, Daniel F. Freitag, Jennifer Wessel, Inês Barroso, Jette Bork-Jensen, Marit E. Jørgensen, Torben Hansen, Nita G. Forouhi, Jennifer A. Smith, Peter Vollenweider, Douglas F. Easton, Heiner Boeing, Helena M. Earl, Laufey T. Amundadottir, Annette Peters, Ingrid B. Borecki, L. Adrienne Cupples, Li Li, Josée Dupuis, Sara Benlloch Garcia, J. Wouter Jukema, Shuai Wang, Veikko Salomaa, Jukka Kontto, Timothy J. Key, Yuning Chen, Sune F. Nielsen, Robin Young, Jing Hua Zhao, Andrew P. Morris, Larraitz Arriola, Claudia Langenberg, Joshua C. Bis, Nisa M. Maruthur, Ele Ferrannini, Joanna M. M. Howson, Marcel den Hoed, Jeanette Erdmann, Rosalind A. Eeles, Daphne L. van der A, Panos Deloukas, Eric Boerwinkle, Sara M. Willems, Elio Riboli, Markku Laakso, Gina M. Peloso, Muriel J. Caslake, Nadia Slimani, Zsofia Kote-Jarai, Paul W. Franks, EPIC-InterAct, Dominique Arveiler, Sarah Bowden, Janet A. Dunn, Jan-Håkan Jansson, Carlos Cruchaga, Audrey Y. Chu, James S. Pankow, Rudolf Kaaks, Jerome I. Rotter, Jaspal S. Kooner, Ailith Pirie, Johanna Kuusisto, Hanieh Yaghootkar, Niels Grarup, Danish Saleheen, Thomas Foltynie, Jean Abraham, Stefan Blankenberg, Mark O. Goodarzi, Markus Perola, Olov Rolandsson, Chris J. Packard, Praveen Surendran, Allan Linneberg, Beverley Balkau, Christopher J. Poole, Frank Kee, Carmen Navarro, Nicholas J. Wareham, Oluf Pedersen, Heribert Schunkert, Domenico Palli, Patricia B. Munroe, Sven J. van der Lee, Chunyu Liu, Rebecca Sims, Georg Ehret, Michael Boehnke, Stephen J. Sharp, Peter M. Nilsson, Salvatore Panico, Børge G. Nordestgaard, Aldi T. Kraja, Sara Grioni, Sekar Kathiresan, Dawn M. Waterworth, Francesco Gianfagna, Jacek Czajkowski, Naveed Sattar, Margaret G. Ehm, Christopher J. Gillson, Karen L. Mohlke, Stella Trompet, John Danesh, Carlotta Sacerdote, Gaëlle Marenne, Jian'an Luan, Timothy M. Frayling, J. Ramón Quirós, Iciar Aviles-Olmos, Robert A. Scott, Yvonne T. van der Schouw, Jennifer L. Aponte, María José Sánchez, Deborah J. Thompson, Klaudia Walter, James B. Meigs, Tibor V. Varga, Kari Kuulasmaa, Torben Jørgensen, Rosario Tumino, Kyriaki Michailidou, Kenneth Muir, Philippe Amouyel, Ian Ford, Aurelio Barricarte, Stephen O'Rahilly, Ali Amin Al Olama, Louise Hiller, Alena Stančáková, Carlos Caldas, Jean Ferrières

المساهمون: Scott, Robert A, Freitag, Daniel F, Li, Li, Chu, Audrey Y, Surendran, Praveen, Young, Robin, Grarup, Niel, Stancáková, Alena, Chen, Yuning, Varga, Tibor V, Yaghootkar, Hanieh, Luan, Jian'An, Zhao, Jing Hua, Willems, Sara M, Wessel, Jennifer, Wang, Shuai, Maruthur, Nisa, Michailidou, Kyriaki, Pirie, Ailith, van der Lee, Sven J, Gillson, Christopher, Al Olama, Ali Amin, Amouyel, Philippe, Arriola, Larraitz, Arveiler, Dominique, Aviles Olmos, Iciar, Balkau, Beverley, Barricarte, Aurelio, Barroso, Inê, Garcia, Sara Benlloch, Bis, Joshua C, Blankenberg, Stefan, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Borecki, Ingrid B, Bork Jensen, Jette, Bowden, Sarah, Caldas, Carlo, Caslake, Muriel, Cupples, L. Adrienne, Cruchaga, Carlo, Czajkowski, Jacek, den Hoed, Marcel, Dunn, Janet A, Earl, Helena M, Ehret, Georg B, Ferrannini, Ele, Ferrieres, Jean, Foltynie, Thoma, Ford, Ian, Forouhi, Nita G, Gianfagna, Francesco, Gonzalez, Carlo, Grioni, Sara, Hiller, Louise, Jansson, Jan Håkan, Jørgensen, Marit E, Jukema, J. Wouter, Kaaks, Rudolf, Kee, Frank, Kerrison, Nicola D, Key, Timothy J, Kontto, Jukka, Kote Jarai, Zsofia, Kraja, Aldi T, Kuulasmaa, Kari, Kuusisto, Johanna, Linneberg, Allan, Liu, Chunyu, Marenne, Gaëlle, Mohlke, Karen L, Morris, Andrew P, Muir, Kenneth, Müller Nurasyid, Martina, Munroe, Patricia B, Navarro, Carmen, Nielsen, Sune F, Nilsson, Peter M, Nordestgaard, Børge G, Packard, Chris J, Palli, Domenico, Panico, Salvatore, Peloso, Gina M, Perola, Marku, Peters, Annette, Poole, Christopher J, Quirós, J. Ramón, Rolandsson, Olov, Sacerdote, Carlotta, Salomaa, Veikko, Sánchez, María José, Sattar, Naveed, Sharp, Stephen J, Sims, Rebecca, Slimani, Nadia, Smith, Jennifer A, Thompson, Deborah J, Trompet, Stella, Tumino, Rosario, van der A, Daphne L, van der Schouw, Yvonne T, Virtamo, Jarmo, Walker, Mark, Walter, Klaudia, Abraham, Jean E, Amundadottir, Laufey T, Aponte, Jennifer L, Butterworth, Adam S, Dupuis, Josée, Easton, Douglas F, Eeles, Rosalind A, Erdmann, Jeanette, Franks, Paul W, Frayling, Timothy M, Hansen, Torben, Howson, Joanna M. M, Jørgensen, Torben, Kooner, Jaspal, Laakso, Markku, Langenberg, Claudia, Mccarthy, Mark I, Pankow, James S, Pedersen, Oluf, Riboli, Elio, Rotter, Jerome I, Saleheen, Danish, Samani, Nilesh J, Schunkert, Heribert, Vollenweider, Peter, O'Rahilly, Stephen, Deloukas, Pano, Danesh, John, Goodarzi, Mark O, Kathiresan, Sekar, Meigs, James B, Ehm, Margaret G, Wareham, Nicholas J, Waterworth, Dawn M., Surgery, Epidemiology, Ehret, Georg Benedikt, Surendran, Praveen [0000-0002-4911-6077], Luan, Jian'an [0000-0003-3137-6337], Barroso, Ines [0000-0001-5800-4520], Caldas, Carlos [0000-0003-3547-1489], Earl, Helena [0000-0003-1549-8094], Forouhi, Nita [0000-0002-5041-248X], Sharp, Stephen [0000-0003-2375-1440], Thompson, Deborah [0000-0003-1465-5799], Abraham, Jean [0000-0003-0688-4807], Butterworth, Adam [0000-0002-6915-9015], Easton, Douglas [0000-0003-2444-3247], Howson, Joanna [0000-0001-7618-0050], Langenberg, Claudia [0000-0002-5017-7344], O'Rahilly, Stephen [0000-0003-2199-4449], Danesh, John [0000-0003-1158-6791], Wareham, Nicholas [0000-0003-1422-2993], Apollo - University of Cambridge Repository

المصدر: 341ra76
Scott, R A, Freitag, D F, Li, L, Chu, A Y, Surendran, P, Young, R, Grarup, N, Stancáková, A, Chen, Y, Varga, T V, Yaghootkar, H, Luan, J, Zhao, J H, Willems, S M, Wessel, J, Wang, S, Maruthur, N, Michailidou, K, Pirie, A, van der Lee, S J, Gillson, C, Al Olama, A A, Amouyel, P, Arriola, L, Arveiler, D, Aviles-Olmos, I, Balkau, B, Barricarte, A, Barroso, I, Garcia, S B, Bis, J C, Blankenberg, S, Boehnke, M, Boeing, H, Boerwinkle, E, Borecki, I B, Bork-Jensen, J, Bowden, S, Caldas, C, Caslake, M, Cupples, L A, Cruchaga, C, Czajkowski, J, den Hoed, M, Dunn, J A, Earl, H M, Ehret, G B, Ferrannini, E, Ferrieres, J, Jørgensen, T & CVD50 consortium 2016, ' A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease ', Science Translational Medicine, vol. 8, no. 341, 341ra76 . https://doi.org/10.1126/scitranslmed.aad3744Test
Scott, R A, Freitag, D F, Li, L, Chu, A Y, Surendran, P, Young, C R, Grarup, N, Stancakova, A, Chen, Y, Varga, T V, Yaghootkar, H, Luan, J, Zhao, J H, Willems, S M, Wessel, J, Wang, S, Maruthur, N M, Michailidou, K, Pirie, A, Van Der Lee, S J, Gillson, C J, Amin Al Olama, A, Amouyel, P, Arriola, L, Arveiler, D, Aviles-Olmos, I, Balkau, B, Barricarte, A, Barroso, I, Garcia, S B, Bis, J C, Blankenberg, S, Boehnke, M, Boeing, H, Boerwinkle, E, Borecki, I B, Bork-Jensen, J, Bowden, S, Caldas, C, Caslake, M, Cupples, L A, Cruchaga, C, Czajkowski, J, den Hoed, M, Dunn, J A, Earl, H M, Ehret, G B, Ferrannini, E, Ferrieres, J, Foltynie, T, Ford, I, Forouhi, N G, Gianfagna, F, Gonzalez, C A, Grioni, S, Hiller, L, Jansson, J H, Jørgensen, M E, Jukema, J W, Kaaks, R, Kee, F, Kerrison, N D, J. Key, T, Kontto, J, Kote-Jarai, Z, Kraja, A T, Kuulasmaa, K, Kuusisto, J, Linneberg, A, Liu, C, Marenne, G, Mohlke, K L, Morris, A P, Muir, K, Müller-Nurasyid, M, Munroe, P B, Navarro, C, Nielsen, S F, Nilsson, P M, Nordestgaard, B G, Packard, C J, Palli, D, Panico, S, Peloso, G M, Perola, M, Peters, A, Poole, C J, Quiros, J R, Rolandsson, O, Sacerdote, C, Salomaa, V, Sánchez, M-J, Sattar, N, Sharp, S J, Sims, R, Slimani, N, Smith, J A, Thompson, J D, Trompet, S, Tumino, R, van der A, D L, van der Schouw, Y T, Virtamo, J, Walker, M, Walter, K, Abraham, J E, Amundadottir, L T, Butterworth, A S, Aponte, J L, Dupuis, J, Easton, D F, Eeles, R A, Erdmann, J, Franks, P W, Frayling, T M, Hansen, T, Howson, J M M, Jørgensen, T, Kooner, J, Laakso, M, McCarthy, M I, Pankow, J S, Pedersen, O, Riboli, E, Rotter, J I, Saleheen, D, Samani, N J, Schunkert, H, Vollenweider, P, O'Rahilly, S, Deloukas, P, Danesh, J, Goodarzi, M O, Kathiresan, S, Meigs, J B, Ehm, M G, Wareham, N J & Waterworth, D M 2016, ' A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease ', Science Translational Medicine, bind 8, nr. 341 . https://doi.org/10.1126/scitranslmed.aad3744Test
SCIENCE TRANSLATIONAL MEDICINE
Scott, R A, Freitag, D F, Li, L, Chu, A Y, Surendran, P, Young, R, Grarup, N, Stancáková, A, Chen, Y, Varga, T V, Yaghootkar, H, Luan, J, Zhao, J H, Willems, S M, Wessel, J, Wang, S, Maruthur, N, Michailidou, K, Pirie, A, van der Lee, S J, Gillson, C, Al Olama, A A, Amouyel, P, Arriola, L, Arveiler, D, Aviles-Olmos, I, Balkau, B, Barricarte, A, Barroso, I, Garcia, S B, Bis, J C, Blankenberg, S, Boehnke, M, Boeing, H, Boerwinkle, E, Borecki, I B, Bork-Jensen, J, Bowden, S, Caldas, C, Caslake, M, Cupples, L A, Cruchaga, C, Czajkowski, J, den Hoed, M, Dunn, J A, Earl, H M, Ehret, G B, Ferrannini, E & Ferrieres, J & Foltynie, T 2016, ' A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease ', Science Translational Medicine, vol. 8, no. 341, pp. 341ra76 . https://doi.org/10.1126/scitranslmed.aad3744Test
Science Translational Medicine, 8(341)
Science Translational Medicine, 8(341):341ra76. American Association for the Advancement of Science
Science Translational Medicine, Vol. 8, No 341 (2016) P. 341ra76
Science Translational Medicine, 8(341). American Association for the Advancement of Science

مصطلحات موضوعية: Type 2/genetics, 0301 basic medicine, Somatostatin/genetics, Heart disease, Epidemiology, CHARGE consortium, Obesity/genetics, RECEPTOR AGONIST LIXISENATIDE, Coronary Disease, Type 2 diabetes, Research & Experimental Medicine, Bioinformatics, PLACEBO-CONTROLLED TRIAL, Receptor, Cannabinoid, CB2, DOUBLE-BLIND, Dipeptidyl Peptidase 4/genetics, 0302 clinical medicine, ONCE-DAILY LIXISENATIDE, Receptors, Receptor, Serotonin, 5-HT2C, Receptors, Somatostatin, Exome sequencing, GLUCAGON-LIKE PEPTIDE-1, CHD Exome+ Consortium, Neurology Working Group of the Cohorts for Heart, General Medicine, 11 Medical And Health Sciences, RANDOMIZED CONTROLLED-TRIAL, 3. Good health, Coronary Disease/genetics, 5-HT2C/genetics, CVD50 consortium, Drug development, Medicine, Research & Experimental, EPIC-InterAct, Public Health, Life Sciences & Biomedicine, INCRETIN-BASED THERAPIES, Receptor, Serotonin, RM, European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD), Genotype, Dipeptidyl Peptidase 4, CB2/genetics, TYPE-2 DIABETES-MELLITUS, 030209 endocrinology & metabolism, Article, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Sodium-Glucose Transporter 1, BETA-CELL FUNCTION, Diabetes mellitus, Diabetes Mellitus, Journal Article, medicine, Humans, Sodium-Glucose Transporter 1/genetics, Obesity, Cannabinoid, Alleles, Science & Technology, business.industry, Alzheimer’s Disease Genetics Consortium, Glucagon-Like Peptide-1 Receptor/genetics, GERAD_EC Consortium, Cell Biology, 06 Biological Sciences, medicine.disease, R1, Human genetics, CARDIOGRAM Exome Consortium, Clinical trial, Minor allele frequency, BODY-MASS INDEX, 030104 developmental biology, Diabetes Mellitus, Type 2, Aging Research in Genomic Epidemiology (CHARGE), business, RC, Pancreatic Cancer Cohort Consortium

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2df1af35c1e4c46ac1448dacdbce98Test
http://hdl.handle.net/11588/650489Test