المؤلفون: Sanvicente García, Marta

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

مرشدي الرسالة: Güell Cargol, Marc

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Genome editing, bioinformatics, PRDM9, homology directed repair, CRISPR-Cas systems, Edició genòmica, bioinformàtica, reparació dirigida per homologia

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/688355Test

المؤلفون: Hagen, Kari D, Hart, Christopher JS, McInally, Shane G, Dawson, Scott C

المصدر: Genetics. 227(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Genetics, Biological Sciences, Digestive Diseases, Emerging Infectious Diseases, Biotechnology, Biodefense, Infectious Diseases, Giardia, Giardiasis, Protozoan Proteins, Humans, CRISPR-Cas Systems, Animals, CRISPR/Cas9, morpholino, CRISPRi, Cre-Lox, Developmental Biology, Biochemistry and cell biology

الوصول الحر: https://escholarship.org/uc/item/0gv0g36gTest

المؤلفون: Mowery, Cody T, Freimer, Jacob W, Chen, Zeyu, Casaní-Galdón, Salvador, Umhoefer, Jennifer M, Arce, Maya M, Gjoni, Ketrin, Daniel, Bence, Sandor, Katalin, Gowen, Benjamin G, Nguyen, Vinh, Simeonov, Dimitre R, Garrido, Christian M, Curie, Gemma L, Schmidt, Ralf, Steinhart, Zachary, Satpathy, Ansuman T, Pollard, Katherine S, Corn, Jacob E, Bernstein, Bradley E, Ye, Chun Jimmie, Marson, Alexander

المصدر: Nature Genetics. 56(6)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Human Genome, Biotechnology, 1.1 Normal biological development and functioning, Underpinning research, Humans, CTLA-4 Antigen, CD28 Antigens, Gene Expression Regulation, Chromatin, T-Lymphocytes, Inducible T-Cell Co-Stimulator Protein, CCCTC-Binding Factor, CRISPR-Cas Systems, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2jm527bjTest
https://escholarship.org/content/qt2jm527bj/qt2jm527bj.pdfTest

المؤلفون: Halasz, Haley, Malekos, Eric, Covarrubias, Sergio, Yitiz, Samira, Montano, Christy, Sudek, Lisa, Katzman, Sol, Liu, S, Horlbeck, Max, Namvar, Leila, Weissman, Jonathan, Carpenter, Susan

المصدر: Proceedings of the National Academy of Sciences. 121(22)

مصطلحات موضوعية: CRISPRi, inflammation, long noncoding RNA, macrophage, short encoded peptide, RNA, Long Noncoding, Humans, Macrophages, Cell Differentiation, Signal Transduction, Monocytes, Inflammation, Toll-Like Receptor 4, NF-kappa B, Trans-Activators, Proto-Oncogene Proteins, CRISPR-Cas Systems, Gene Expression Regulation

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7p5045j3Test
https://escholarship.org/content/qt7p5045j3/qt7p5045j3.pdfTest

المؤلفون: Berjis, Abdulla, Muthumani, Deeksha, Aguilar, Oscar, Pomp, Oz, Johnson, Omar, Finck, Amanda, Engel, Nils, Chen, Linhui, Plachta, Nicolas, Scholler, John, June, Carl, Sheppard, Neil, Lanier, Lewis

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Granzymes, Interleukin-15, Killer Cells, Natural, Apoptosis, Humans, Interleukin-18, Animals, Cryopreservation, Mice, Cell Line, Tumor, CRISPR-Cas Systems

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5f2742z4Test

المؤلفون: Enustun, Eray, Armbruster, Emily G, Lee, Jina, Zhang, Sitao, Yee, Brian A, Malukhina, Kseniya, Gu, Yajie, Deep, Amar, Naritomi, Jack T, Liang, Qishan, Aigner, Stefan, Adler, Benjamin A, Cress, Brady F, Doudna, Jennifer A, Chaikeeratisak, Vorrapon, Cleveland, Don W, Ghassemian, Majid, Bintu, Bogdan, Yeo, Gene W, Pogliano, Joe, Corbett, Kevin D

المصدر: Nucleic Acids Research. 52(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Biotechnology, Infection, Bacteriophages, RNA-Binding Proteins, RNA, Messenger, Cell Nucleus, Viral Proteins, RNA, Viral, CRISPR-Cas Systems, Virus Assembly, Genome, Viral, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4vt1n111Test

المؤلفون: Scranton, Kyle, John, Scott, Angelini, Marina, Steccanella, Federica, Umar, Soban, Zhang, Rui, Olcese, Riccardo, Goldhaber, Joshua, Ottolia, Michela

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Sodium-Calcium Exchanger, Animals, Myocytes, Cardiac, Male, Sodium, Mice, Action Potentials, Calcium, Myocardial Contraction, Heart, Humans, Mutation, CRISPR-Cas Systems

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7467j9n7Test

المؤلفون: Mudde, Anne CA, Kuo, Caroline Y, Kohn, Donald B, Booth, Claire

المصدر: The Journal of Allergy and Clinical Immunology In Practice. 12(5)

مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, Pediatric, Genetics, Stem Cell Research, Biotechnology, Regenerative Medicine, Gene Therapy, Development of treatments and therapeutic interventions, 5.2 Cellular and gene therapies, Inflammatory and immune system, Humans, Gene Editing, Genetic Therapy, Animals, CRISPR-Cas Systems, Agammaglobulinemia, Severe Combined Immunodeficiency, Hematopoietic Stem Cell Transplantation, Gene editing, Inborn errors of immunity, CRISPR/Cas, Prime editing, Base editing, Immunology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0vw218bhTest
https://escholarship.org/content/qt0vw218bh/qt0vw218bh.pdfTest

المؤلفون: Keener, Rebecca, Chhetri, Surya B, Connelly, Carla J, Taub, Margaret A, Conomos, Matthew P, Weinstock, Joshua, Ni, Bohan, Strober, Benjamin, Aslibekyan, Stella, Auer, Paul L, Barwick, Lucas, Becker, Lewis C, Blangero, John, Bleecker, Eugene R, Brody, Jennifer A, Cade, Brian E, Celedon, Juan C, Chang, Yi-Cheng, Cupples, L Adrienne, Custer, Brian, Freedman, Barry I, Gladwin, Mark T, Heckbert, Susan R, Hou, Lifang, Irvin, Marguerite R, Isasi, Carmen R, Johnsen, Jill M, Kenny, Eimear E, Kooperberg, Charles, Minster, Ryan L, Naseri, Take, Viali, Satupa’itea, Nekhai, Sergei, Pankratz, Nathan, Peyser, Patricia A, Taylor, Kent D, Telen, Marilyn J, Wu, Baojun, Yanek, Lisa R, Yang, Ivana V, Albert, Christine, Arnett, Donna K, Ashley-Koch, Allison E, Barnes, Kathleen C, Bis, Joshua C, Blackwell, Thomas W, Boerwinkle, Eric, Burchard, Esteban G, Carson, April P, Chen, Zhanghua, Chen, Yii-Der Ida, Darbar, Dawood, de Andrade, Mariza, Ellinor, Patrick T, Fornage, Myriam, Gelb, Bruce D, Gilliland, Frank D, He, Jiang, Islam, Talat, Kaab, Stefan, Kardia, Sharon LR, Kelly, Shannon, Konkle, Barbara A, Kumar, Rajesh, Loos, Ruth JF, Martinez, Fernando D, McGarvey, Stephen T, Meyers, Deborah A, Mitchell, Braxton D, Montgomery, Courtney G, North, Kari E, Palmer, Nicholette D, Peralta, Juan M, Raby, Benjamin A, Redline, Susan, Rich, Stephen S, Roden, Dan, Rotter, Jerome I, Ruczinski, Ingo, Schwartz, David, Sciurba, Frank, Shoemaker, M Benjamin, Silverman, Edwin K, Sinner, Moritz F, Smith, Nicholas L, Smith, Albert V, Tiwari, Hemant K, Vasan, Ramachandran S, Weiss, Scott T, Williams, L Keoki, Zhang, Yingze, Ziv, Elad, Raffield, Laura M, Reiner, Alexander P, Arvanitis, Marios, Greider, Carol W, Mathias, Rasika A, Battle, Alexis

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Biological Sciences, Genetics, Human Genome, Clinical Research, Underpinning research, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group, K562 Cells, Telomere, Humans, Gene Expression Regulation, Polymorphism, Single Nucleotide, Genome-Wide Association Study, Telomere Homeostasis, CRISPR-Cas Systems

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6gg7t188Test
https://escholarship.org/content/qt6gg7t188/qt6gg7t188.pdfTest

المؤلفون: Yan, Jun, Oyler-Castrillo, Paul, Ravisankar, Purnima, Ward, Carl C, Levesque, Sébastien, Jing, Yangwode, Simpson, Danny, Zhao, Anqi, Li, Hui, Yan, Weihao, Goudy, Laine, Schmidt, Ralf, Solley, Sabrina C, Gilbert, Luke A, Chan, Michelle M, Bauer, Daniel E, Marson, Alexander, Parsons, Lance R, Adamson, Britt

المصدر: Nature. 628(8008)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Humans, CRISPR-Cas Systems, Gene Editing, K562 Cells, Poly U, RNA Polymerase III, RNA, Guide, CRISPR-Cas Systems, RNA-Binding Proteins, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1x77g827Test