المؤلفون: Lau, Darryl, Magill, Stephen T, Aghi, Manish K

المصدر: Neurosurgical FOCUS. 37(6)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Brain Cancer, Brain Disorders, Orphan Drug, Cancer, Neurosciences, Evaluation of treatments and therapeutic interventions, Development of treatments and therapeutic interventions, 6.1 Pharmaceuticals, 5.1 Pharmaceuticals, Brain Neoplasms, Glioblastoma, Humans, Molecular Targeted Therapy, Neoplasm Recurrence, Local, combination treatment, glioblastoma, molecular therapy, overall survival, progression-free survival, recurrent, BBB = blood-brain barrier, CR = complete response, EGFR = epidermal growth factor receptor, MGMT = methyguanine DNA methyltransferase, OS = overall survival, PD = progressive disease, PDGFR = platelet-derived growth factor receptor, PFS = progression-free survival, PKC = protein kinase C, PR = partial response, RTK = receptor tyrosine kinase, RTKI = RTK inhibitor, SD = stable disease, TCGA = The Cancer Genome Atlas, VEGF = vascular endothelial growth factor, VEGFR = VEGF receptor, mTOR = mammalian target of rapamycin, Clinical Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4nb66879Test

المؤلفون: Liang Ouyang, Yao Liu, Jie Liu, Lu Feng, Guan Wang, Yi Chen, Meng Wang, Tingting Jiang

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 355-372 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: NTRK, neurotrophic receptor tyrosine kinase, FISH, fluorescence in situ hybridization, Review, Tropomyosin receptor kinase B, HNSCC, head and neck squamous cell carcinoma, Tropomyosin receptor kinase A, HTS, high-throughput screening, ring finger and WD repeat domain 2, E3 ubiquitin protein ligase, Tropomyosin receptor kinase C, LMNA, lamin A/C, Receptor tyrosine kinase, TPM3, tropomyosin 3, 0302 clinical medicine, MASC, mammary analogue secretory carcinoma, PROTAC proteolysis targeting chimera, QKI, SQSTM1, sequestosome 1, TPR, translocated promoter region, General Pharmacology, Toxicology and Pharmaceutics, RABGTPase activating protein 1-like, RFWD2, AML, acute myeloid leukemia, 0303 health sciences, ICC, intrahepatic cholangiocarcinoma, TRK, tropomyosin receptor kinase, Neurotrophic receptor tyrosine kinase fusions, PPL, periplakin, TP53, tumor protein P53, SBC, secretory breast carcinoma, OAK, osteoarthritis of the knee, TFG, TRK-fused gene, ARHGEF2, Rho/Rac guanine nucleotide exchange factor 2, NT3, neurotrophin-3, quaking I protein, RABGAP1L, ETV6, ETS translocation variant 6, 030220 oncology & carcinogenesis, CR, complete response, CRC, colorectal cancer, BCAN, brevican, BDNF, brain-derived neurotrophic factor, BTBD1, BTB (POZ) domain containing 1, RTK, receptor tyrosine kinase, DOR, durable objective responses, CDK-2, cyclin-dependent kinase 2, Tyrosine kinase, EWG, electron-withdrawing group, ORR, overall response rate, Neurotrophin, NCCN, National Comprehensive Cancer Network, VCL, vinculin, NGF, nerve growth factor, MPRIP, myosin phosphatase Rho interacting protein, Biology, PAN3, poly(A) nuclease 3, TRIM24, tripartite motif containing 24, Small-molecule inhibitor, NTRK fusion cancer, SCYL3, SCY1 like pseudokinase 3, 03 medical and health sciences, NACC2, NACC family member 2, NSCLC, non-small cell lung cancer, SAR, structure–activity relationship, Protein kinase B, VEGFR2, vascular endothelial growth factor receptor 2, 030304 developmental biology, DFG, Asp-Phe-Gly, CTCs, sequencing of circulating tumor cells, lcsh:RM1-950, GBM, glioblastoma multiforme, NFASC, neurofascin, NGS, next-generation sequencing of tumor tissue, FDA, U.S. Food and Drug Administration, lcsh:Therapeutics. Pharmacology, nervous system, Trk receptor, IG-C2, Ig-like C2 type I, Cancer research, biology.protein, Tropomyosin receptor kinase, AFAP1, actin filament-associated protein 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c737a8f0c0bb6776695689290564cb8aTest
http://www.sciencedirect.com/science/article/pii/S2211383520305864Test

المؤلفون: Michi M. Shinohara, Kelly G. Paulson, Paul Nghiem, Karl D. Lewis, Nora A. Alexander, Candice D. Church, Nancy S. Lee, Song Youn Park

المصدر: JAAD Case Reports, Vol 8, Iss, Pp 28-33 (2021)
JAAD Case Reports

مصطلحات موضوعية: MCPyV, Merkel cell polyomavirus, Immune checkpoint inhibitors, medicine.medical_treatment, MCC, Merkel cell carcinoma, Human immunodeficiency virus (HIV), Merkel cell polyomavirus, Case Report, aMCC, advanced Merkel cell carcinoma, Dermatology, medicine.disease_cause, PET, positron emission tomography, Merkel cell carcinoma, Acquired immunodeficiency syndrome (AIDS), PD-L1, PD-L1, anti-programmed death ligand-1, medicine, lcsh:Dermatology, MCC, biology, PD-1, anti-programmed cell death-1, business.industry, HIV, Immunotherapy, lcsh:RL1-803, RT, radiation treatment, biology.organism_classification, medicine.disease, AIDS, ICI, immune checkpoint inhibitors, CR, complete response, biology.protein, Cancer research, Immunohistochemistry, immunotherapy, business, IHC, immunohistochemistry, anti-PD-(L)1 agent

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc06c2e9d001058c4c8f7e1820262c58Test
http://www.sciencedirect.com/science/article/pii/S2352512620308183Test

المؤلفون: Chi Hou Ng, Mu Shiun Tsai, Mai Huong Thi Nguyen, Jean Lu, Ming Hong Chen, Shu Chen Liu, Nianhan Ma, Long Yuan Li, Jen Chieh Tsai, Chen Huan Lin, Hironobu Ihn, Hsuan Lin, Satoshi Fukushima, Azusa Miyashita, In Yu Lin, Szu Mam Liu

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 789-799 (2020)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, miR-524-5p, Resistance, Mice, 0302 clinical medicine, Medicine, Melanoma, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, STPR, short-term partial response, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, CR, complete response, Biomarker (medicine), RNA Interference, IHC, immunohistochemistry, Proto-Oncogene Proteins B-raf, BRAF inhibitor, Original article, PD, progressive disease, MITF, microphthalmia-associated transcription factor, IPA, ingenuity pathway analysis, ISH, in situ hybridization, lcsh:RC254-282, 03 medical and health sciences, In vivo, Cell Line, Tumor, microRNA, Biomarkers, Tumor, Nevus, Animals, Humans, Liver X receptor, Protein Kinase Inhibitors, neoplasms, Cell Proliferation, miRNA, Dose-Response Relationship, Drug, business.industry, LTPR, long-term partial response, medicine.disease, RECIST, response evaluation criteria in solid tumors, Xenograft Model Antitumor Assays, NGS, next-generation sequencing, Disease Models, Animal, MicroRNAs, 030104 developmental biology, Vemurafenib, Drug Resistance, Neoplasm, Mutation, Cancer research, business, Progressive disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34d1c07ad9f7bf3140c025ea38a8d55Test
http://www.sciencedirect.com/science/article/pii/S1476558620301640Test

المؤلفون: Norihiko Suzuki, Hideyuki Takeuchi, Junji Takahashi, Keigo Nakashima, Shinya Okada, Yutaka Suzuki, Hironori Ohdaira, Hiroshi Ishiguro, Teppei Kamada, Yuichi Nakaseko

المصدر: Annals of Medicine and Surgery

مصطلحات موضوعية: Oncology, medicine.medical_specialty, PD-L1, programmed death ligand 1, medicine.medical_treatment, NCCN, National Comprehensive Cancer Network, Case Report, Pembrolizumab, Pemetrexed, PET, positron emission tomography, Cancer of unknown primary, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Maintenance therapy, Internal medicine, medicine, Lung cancer, Platinum, Chemotherapy, LDH, lactate dehydrogenase, business.industry, ALK, anaplastic lymphoma kinase, CUP, cancer of unknown primary site, General Medicine, medicine.disease, TTF-1, thyroid transcription factor-1, Carboplatin, EGFR, epidermal growth factor receptor, CT, computed tomography, chemistry, 030220 oncology & carcinogenesis, CR, complete response, Adenocarcinoma, 030211 gastroenterology & hepatology, Surgery, CEA, carcinoembryonic antigen, business, CK7, cytokeratin 7, Non-small-cell lung cancer, Progressive disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931c4a2f9e20fcfc3a4cf8a935b4c559Test
http://europepmc.org/articles/PMC7578551Test

المؤلفون: Hui-Chuan Sun, Xiao-Dong Zhu, Zhao-You Tang

المصدر: Genes and Diseases, Vol 7, Iss 3, Pp 328-335 (2020)
Genes & Diseases

مصطلحات موضوعية: 0301 basic medicine, Sorafenib, Oncology, medicine.medical_specialty, PD-L1, program death-1 ligand, lcsh:QH426-470, Combination therapy, Cabozantinib, Hepatocellular carcinoma, ICI, immune checkpoint inhibitor, Pembrolizumab, TKI, tyrosine kinase inhibitor, Biochemistry, Article, Ramucirumab, OS, overall survival, ORR, objective response rate, Combinational therapy, 03 medical and health sciences, chemistry.chemical_compound, PR, partial response, 0302 clinical medicine, RECIST, Response Evaluation Criteria in Solid Tumors, PD-1, program death-1, Regorafenib, Internal medicine, medicine, Molecular targeted therapy, TACE, transcatheter chemoembolization, Molecular Biology, Genetics (clinical), lcsh:R5-920, Systemic therapy, business.industry, Anti-angiogenic therapy, Cell Biology, PFS, progression-free survival, lcsh:Genetics, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, CR, complete response, Nivolumab, HCC, hepatocellular carcinoma, lcsh:Medicine (General), business, Lenvatinib, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb19869f3bc3bfb3bae7b9eaa804f48cTest
https://doi.org/10.1016/j.gendis.2020.03.010Test

المؤلفون: Kang-Shuai Li, Xiao-Dong Zhu, Hui-Chuan Sun

المصدر: Genes and Diseases, Vol 7, Iss 3, Pp 359-369 (2020)
Genes & Diseases

مصطلحات موضوعية: Oncology, RCT, randomized clinical trial, PD-L1, program death-1 ligand, Hepatocellular carcinoma, ICI, immune checkpoint inhibitor, medicine.medical_treatment, TKI, tyrosine kinase inhibitor, Biochemistry, law.invention, ORR, objective response rate, Liver disease, PR, partial response, 0302 clinical medicine, RECIST, Response Evaluation Criteria in Solid Tumors, Randomized controlled trial, law, Medicine, Molecular targeted therapy, 030212 general & internal medicine, Genetics (clinical), lcsh:R5-920, Anti-PD-1 antibody, RFS, recurrence-free survival, Clinical trial, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, CR, complete response, lcsh:Medicine (General), Adjuvant, medicine.drug, Sorafenib, medicine.medical_specialty, lcsh:QH426-470, Adjuvant therapy, Article, OS, overall survival, 03 medical and health sciences, PD-1, program death-1, Internal medicine, TACE, transcatheter chemoembolization, Molecular Biology, business.industry, Cell Biology, medicine.disease, Recurrence-free survival, lcsh:Genetics, HCC, hepatocellular carcinoma, CIK, chemokine-induced killer cells, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389b02e06369d54c5c7cd0a28e191866Test
http://www.sciencedirect.com/science/article/pii/S2352304220300325Test

المؤلفون: Ayatallah A. Youssief, Shimaa Abdalla Ahmed, Mayada Fawzy Sedik, Tareq Salah, Shereen Mamdouh Kamal

المصدر: Journal of Bone Oncology, Vol 31, Iss, Pp 100395-(2021)
Journal of Bone Oncology

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Analgesic, Diseases of the musculoskeletal system, Capecitabine, MF, multiples fraction, Breast cancer, CR, Complete response, Palliative radiotherapy, Medicine, External beam radiotherapy, Prospective cohort study, RC254-282, ComputingMethodologies_COMPUTERGRAPHICS, business.industry, SF, single fraction, Standard treatment, Bone metastases, Bone metastasis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, PR, Partial response, PP, Progressive pain, Radiation therapy, Oncology, RC925-935, Concurrent capecitabine, Pain score, OR, overall response rates, Radiology, business, SP, Stable pain, medicine.drug, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a09cd7d2e2f5bd095ef6dfe143c58c1Test
http://www.sciencedirect.com/science/article/pii/S2212137421000506Test

المؤلفون: Wataru Nakata, Masao Tsujihata, Yuki Horibe, Takayoshi Gotoh, Yuichi Tsujimoto, Goh Tsujimura

المصدر: Urology Case Reports
Urology Case Reports, Vol 41, Iss, Pp 101959-(2022)

مصطلحات موضوعية: PD-L1, medicine.medical_specialty, Urology, Locally advanced, Pembrolizumab, Pelvic wall, medicine.artery, Medicine, Adverse effect, TURBT, transurethral resection of the bladder tumor, Bladder cancer, business.industry, UC, urothelial carcinoma, Complete remission, Leg pain, medicine.disease, Internal iliac artery, Diseases of the genitourinary system. Urology, Surgery, CT, computed tomography, Oncology, CR, complete response, Urothelial carcinoma, RC870-923, business, MRI, magnetic resonance imaging

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e346119b2247816f0256820763c7f9c6Test
http://europepmc.org/articles/PMC8724930Test

المؤلفون: Bader Abdelmaksoud*and Ahmed El-Azony

مصطلحات موضوعية: Recurrent glioblastoma, Tamoxifen, Glioblastoma multiforme, Biopsy, Tumors, Radionecrosis: Pseudoprogression, GBM: Glioblastoma Multiforme, CR: Complete Response, PR: Partial Response, SD: Stable Disease, PD: Progressive Disease, PFS: Progression Free Survival, TTP: Time to Tumor Progression, OS: Overall Survival

وصف الملف: application/pdf

العلاقة: http://medcraveonline.com/JCPCR/JCPCR-06-00195.pdfTest

الإتاحة: http://medcraveonline.com/JCPCR/JCPCR-06-00195.pdfTest