المؤلفون: Hongren Huang, Xue Liu, Liping Wang, Feng Wang

المصدر: Biology of Sex Differences, Vol 15, Iss 1, Pp 1-15 (2024)

مصطلحات موضوعية: Lateral habenula, Glutamatergic neuron, Sex differences, Connectivity map, Medicine, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2042-6410Test

الوصول الحر: https://doaj.org/article/53477be7f5ba4d7c887a48f0be0471eeTest

المؤلفون: Yao‐Yu Hsieh, Jia‐Ling Du, Pei‐Ming Yang

المصدر: Molecular Oncology, Vol 18, Iss 2, Pp 386-414 (2024)

مصطلحات موضوعية: colorectal cancer, connectivity map, drug repositioning, drug resistance, microtubule‐targeting agent, polypharmacology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1574-7891Test; https://doaj.org/toc/1878-0261Test

الوصول الحر: https://doaj.org/article/ac4d479514f04c64864d836760798ff8Test

المؤلفون: Linares, Gabriel, Li, Yichen, Chang, Wen-Hsuan, Rubin-Sigler, Jasper, Mendonca, Stacee, Hong, Sarah, Eoh, Yunsun, Guo, Wenxuan, Huang, Yi-Hsuan, Chang, Jonathan, Tu, Sharon, Dorjsuren, Nomongo, Santana, Manuel, Hung, Shu-Ting, Yu, Johnny, Perez, Joscany, Chickering, Michael, Cheng, Tze-Yuan, Huang, Chi-Chou, Lee, Shih-Jong, Deng, Hao-Jen, Bach, Kieu-Tram, Gray, Kamden, Subramanyam, Vishvak, Rosenfeld, Jeffrey, Alworth, Samuel, Goodarzi, Hani, Ichida, Justin

المصدر: Cell Stem Cell. 30(2)

مصطلحات موضوعية: SYF2, TDP-43, amyotrophic lateral sclerosis, androgens, connectivity map, drug screen, induced pluripotent stem cells, nineteen complex, norgestrel, spliceosome, Mice, Animals, Amyotrophic Lateral Sclerosis, Motor Neurons, Neurodegenerative Diseases, Mutation, DNA-Binding Proteins

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4p4819z7Test
https://escholarship.org/content/qt4p4819z7/qt4p4819z7.pdfTest

المؤلفون: Dubey, Akanksha, Sivaraman, Jayanthi¹

المصدر: Research Journal of Pharmacy and Technology 16(9):4447-4454. 2023

المؤلفون: Dai, Jun, Zheng, Shuyu, Falco, Matías M., Bao, Jie, Eriksson, Johanna, Pikkusaari, Sanna, Forstén, Sofia, Jiang, Jing, Wang, Wenyu, Gao, Luping, Perez-Villatoro, Fernando, Dufva, Olli, Saeed, Khalid, Wang, Yinyin, Amiryousefi, Ali, Färkkilä, Anniina, Mustjoki, Satu, Kauppi, Liisa, Tang, Jing, Vähärautio, Anna

المساهمون: Research Program in Systems Oncology, Faculty of Medicine, Lung Cancer Model Systems, Institute for Molecular Medicine Finland, TRIMM - Translational Immunology Research Program, Research Programs Unit, Digital Precision Cancer Medicine (iCAN), Embryophylo, Department of Obstetrics and Gynecology, HUS Gynecology and Obstetrics, Clinicum, HUS Comprehensive Cancer Center, Department of Clinical Chemistry and Hematology, Medicum, Faculty Common Matters (Faculty of Biology and Environmental Sciences), Genome Stability Group, Department of Biochemistry and Developmental Biology, Department of Mathematics and Statistics, Organismal and Evolutionary Biology Research Programme

مصطلحات موضوعية: Activation, Connectivity map, Growth, Homologous recombination, Integrated analysis, Platform, R package, Signatures, 3122 Cancers

وصف الملف: application/pdf

العلاقة: We thank FIMM High Content Imaging and Analysis unit for imaging services. BSL-2 laboratory for recombinant virus work was provided by Biomedicum Virus Core (HelVi-BVC) supported by Helsinki Institute of Life Science (HiLIFE) and the Faculty of Medicine, University of Helsinki, and Biocenter Finland. The flow cytometry analysis was performed at the HiLife Flow Cytometry Unit, University of Helsinki. Single-cell transcriptomics was performed at FIMM Single-Cell Analytics unit supported by HiLIFE and Biocenter Finland. The results are in part based upon data generated by the TCGA Research Network: https://www.cancer.gov/tcgaTest. Cartoons in Figs. 3a and 4a were created with BioRender.com. This work was supported by The Sigrid Juselius Foundation (A.V., J.T., A.F.), The Cancer Foundation Finland (A.V., S.Z., F.P.), Foundation for the Finnish Cancer Institute (K. Albin Johansson Cancer Research Fellowship for AV), The Academy of Finland projects 289059 (A.V.), 319243 (A.V.), 317680 (J.T.), 320131 (J.T.), 351165 and 351196 (J.T., A.V.), ERA PerMed JTC2020 PARIS/Academy of Finland project 344697 (A.V.), European Research Council No. 716063 (J.T.), HORIZON-MSCA-2021-PF project 101067835 (M.F.), University of Helsinki Research Foundation (J.D., S.Z., F.P.), K. Albin Johanssons stiftelse (S.Z.), Ida Montinin Saeaetioe (S.Z., F.P.), Biomedicum Helsinki Foundation (S.Z., F.P.), Cancer Society of Finland (A.F.), Academy of Finland (grant number 350396 to A.F.), European Union (ERC, SPACE 101076096). Open access funded by Helsinki University Library.; Dai , J , Zheng , S , Falco , M M , Bao , J , Eriksson , J , Pikkusaari , S , Forstén , S , Jiang , J , Wang , W , Gao , L , Perez-Villatoro , F , Dufva , O , Saeed , K , Wang , Y , Amiryousefi , A , Färkkilä , A , Mustjoki , S , Kauppi , L , Tang , J & Vähärautio , A 2024 , ' Tracing back primed resistance in cancer via sister cells ' , Nature Communications , vol. 15 , no. 1 , 1158 . https://doi.org/10.1038/s41467-024-45478-7Test; RIS: urn:28050D9C8112B205404AC6A62ECD156C; RIS: Dai2024; ORCID: /0000-0003-4721-3954/work/154003007; ORCID: /0000-0002-0816-8241/work/154003603; ORCID: /0000-0002-2966-0446/work/154003613; ORCID: /0000-0003-0624-8077/work/154003973; ORCID: /0000-0001-7480-7710/work/154004109; ORCID: /0000-0002-5419-8484/work/154006198; ORCID: /0000-0002-1993-7309/work/154008681; ORCID: /0000-0002-6813-0050/work/154009811; 56444ba5-8069-441b-b66d-4ddc6066a2de; http://hdl.handle.net/10138/571691Test; 001159313700032

الإتاحة: http://hdl.handle.net/10138/571691Test

المؤلفون: Trang Truong, Zoe Liu, B Panizzutti, Jee Hyun Kim, Olivia Dean, Michael Berk, Ken Walder

مصطلحات موضوعية: Biomedical and clinical sciences, Neurosciences, Psychology, Biological psychology, Science & Technology, Life Sciences & Biomedicine, Pharmacology & Pharmacy, Psychiatry, Neurosciences & Neurology, MITOCHONDRIAL COMPLEX I, CELL-ADHESION MOLECULES, HERPES-SIMPLEX, TRANSCRIPTION FACTORS, CONNECTIVITY MAP, DOUBLE-BLIND, EXPRESSION, RIMONABANT, BRAIN, RISK, 200409 Mental health, Faculty of Health, School of Medicine, Institute for Innovation in Mental and Physical Health and Clinical Translation

العلاقة: http://hdl.handle.net/10779/DRO/DU:25194260.v3Test; https://figshare.com/articles/journal_contribution/Network-based_drug_repurposing_for_schizophrenia/25194260Test

الإتاحة: http://hdl.handle.net/10779/DRO/DU:25194260.v3Test
https://figshare.com/articles/journal_contribution/Network-based_drug_repurposing_for_schizophrenia/25194260Test

المؤلفون: Eri Wakai, Takashi Shiromizu, Shota Otaki, Junko Koiwa, Satoshi Tamaru, Yuhei Nishimura

المصدر: Pharmaceuticals, Vol 17, Iss 1, p 82 (2024)

مصطلحات موضوعية: drug-induced liver injury, drug repositioning, gene expression signature, connectivity map, FDA adverse event reporting system, zebrafish, Medicine, Pharmacy and materia medica, RS1-441

العلاقة: https://www.mdpi.com/1424-8247/17/1/82Test; https://doaj.org/toc/1424-8247Test; https://doaj.org/article/00300a45eabd413aa9a0d62689e2cf3cTest

الإتاحة: https://doi.org/10.3390/ph17010082Test
https://doaj.org/article/00300a45eabd413aa9a0d62689e2cf3cTest

المؤلفون: Chang Su, Cai-yan Cheng, Zheng Rong, Jing-cheng Yang, Zhi-mei Li, Jing-yue Yao, An Liu, Le Yang, Ming-gao Zhao

المصدر: Heliyon, Vol 9, Iss 12, Pp e22605- (2023)

مصطلحات موضوعية: Hepatocellular carcinoma, Connectivity map, Fluphenazine, Autophagy, Drug repurposing, Chronic pain, Science (General), Q1-390, Social sciences (General), H1-99

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2405844023098134Test; https://doaj.org/toc/2405-8440Test

الوصول الحر: https://doaj.org/article/9853eb99014842f1a9de7dabae16e2d0Test

المؤلفون: Xue-Zhen Liang, Xiao-Chen Liu, Song Li, Ming-Tao Wen, Yan-Rong Chen, Di Luo, Bo Xu, Nian-Hu Li, Gang Li

المصدر: Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-23 (2023)

مصطلحات موضوعية: Steroid-induced osteonecrosis of the femoral head, Immune cell infiltration, Noncoding RNA, Competing endogenous RNA, Connectivity map database, Drug gene interaction database, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1749-799XTest

الوصول الحر: https://doaj.org/article/c9823abec0094a0284a34d01de18878bTest

المؤلفون: Yue-Mei Yan, Meng-Zhu Jin, Sheng-Hua Li, Yun Wu, Qiang Wang, Fei-Fei Hu, Chen Shen, Wen-Hao Yin

المصدر: Frontiers in Genetics, Vol 14 (2023)

مصطلحات موضوعية: systemic sclerosis, weighted gene co-expression network analysis, connectivity map, molecular docking, phosphodiesterase inhibitors, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fgene.2023.1202561/fullTest; https://doaj.org/toc/1664-8021Test

الوصول الحر: https://doaj.org/article/a43c8f2dbd2e48238a2fd0595c9895a2Test