المؤلفون: Filipa C. Ferreira, Camilla D. Buarque, Miquéias Lopes-Pacheco

المصدر: Molecules, Vol 29, Iss 4, p 821 (2024)

مصطلحات موضوعية: CFTR corrector, CFTR potentiator, cystic fibrosis, drug development, mechanism of action, molecular structure, Organic chemistry, QD241-441

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1420-3049/29/4/821Test; https://doaj.org/toc/1420-3049Test

الوصول الحر: https://doaj.org/article/5abfdc1f3d7343b399545f581ac76e42Test

المؤلفون: Martinez, Fernando J, Criner, Gerard J, Gessner, Christian, Jandl, Margret, Scherbovsky, Fernando, Shinkai, Masaharu, Siler, Thomas M, Vogelmeier, Claus F, Voves, Robert, Wedzicha, Jadwiga A, Bartels, Christian, Bottoli, Ivan, Byiers, Stuart, Cardenas, Pamela, Eckert, Joerg H, Gutzwiller, Florian S, Knorr, Barbara, Kothari, Mahavir, Parlikar, Rutvick, Tanase, Ana-Maria, Franssen, Frits M E

المصدر: Martinez , F J , Criner , G J , Gessner , C , Jandl , M , Scherbovsky , F , Shinkai , M , Siler , T M , Vogelmeier , C F , Voves , R , Wedzicha , J A , Bartels , C , Bottoli , I , Byiers , S , Cardenas , P , Eckert , J H , Gutzwiller , F S , Knorr , B , Kothari , M , Parlikar , R , Tanase , A-M & Franssen , F M E 2023 , ' Icenticaftor, a CFTR Potentiator, ....

مصطلحات موضوعية: CFTR dysfunction, CFTR potentiator, COPD, chronic bronchitis, icenticaftor, Humans, Cystic Fibrosis Transmembrane Conductance Regulator/genetics, Cough/drug therapy complications, Pulmonary Disease, Chronic Obstructive, Bronchitis, Chronic, Double-Blind Method, Forced Expiratory Volume, Treatment Outcome

العلاقة: https://cris.maastrichtuniversity.nl/en/publications/4b4239bf-de41-4aba-b4d0-574081894e2eTest

الإتاحة: https://doi.org/10.1164/rccm.202303-0458OCTest
https://cris.maastrichtuniversity.nl/en/publications/4b4239bf-de41-4aba-b4d0-574081894e2eTest

المؤلفون: Rowe SM, Jones I, Dransfield MT, Haque N, Gleason S, Hayes KA, Kulmatycki K, Yates DP, Danahay H, Gosling M, Rowlands DJ, Grant SS

المصدر: International Journal of COPD, Vol Volume 15, Pp 2399-2409 (2020)

مصطلحات موضوعية: chronic obstructive pulmonary disease, chronic bronchitis, cystic fibrosis transmembrane conductance regulator (cftr) potentiator, mucociliary clearance, qbw251, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/efficacy-and-safety-of-theTest-cftr-potentiatornbspicenticaftor-qbw251-in--peer-reviewed-article-COPD; https://doaj.org/toc/1178-2005Test

الوصول الحر: https://doaj.org/article/7fca65db81524b9888847d498710aa20Test

المؤلفون: Ferrera L., Cappiello F., Loffredo M. R., Puglisi E., Casciaro B., Botta B., Galietta L. J. V., Mori M., Mangoni M. L.

المساهمون: Ferrera, L., Cappiello, F., Loffredo, M. R., Puglisi, E., Casciaro, B., Botta, B., Galietta, L. J. V., Mori, M., Mangoni, M. L.

مصطلحات موضوعية: Antibiotic-resistance, Antimicrobial peptide, CFTR potentiator, Innate immunity, Lung pathology, Pulmonary drug delivery, Animal, Anti-Bacterial Agent, Bicarbonate, Chloride, Cystic Fibrosi, Cystic Fibrosis Transmembrane Conductance Regulator, Human, Ion Transport, Lung Disease, Pseudomonas Infection, Pseudomonas aeruginosa, Rat, Rats, Inbred F344

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34971429; info:eu-repo/semantics/altIdentifier/wos/WOS:000736790100005; volume:79; issue:1; firstpage:67; journal:CELLULAR AND MOLECULAR LIFE SCIENCES; http://hdl.handle.net/11573/1610735Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85122505018

الإتاحة: https://doi.org/10.1007/s00018-021-04030-2Test
http://hdl.handle.net/11573/1610735Test

المؤلفون: Stéphanie Bui, Alexandra Masson, Raphaël Enaud, Léa Roditis, Gaël Dournes, François Galode, Cyrielle Collet, Emmanuel Mas, Jeanne Languepin, Michael Fayon, Fabien Beaufils, Marie Mittaine

المصدر: Frontiers in Pediatrics, Vol 9 (2021)

مصطلحات موضوعية: cystic fibrosis, child, CFTR potentiator, CFTR corrector, lung function testing, nutritional status, Pediatrics, RJ1-570

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fped.2021.744705/fullTest; https://doaj.org/toc/2296-2360Test

الوصول الحر: https://doaj.org/article/cf2af5d930334a16a3f31dfa40ab41d4Test

المؤلفون: Martina Gentzsch, Deborah M. Cholon, Nancy L. Quinney, Mary E. B. Martino, John T. Minges, Susan E. Boyles, Tara N. Guhr Lee, Charles R. Esther, Carla M. P. Ribeiro

المصدر: Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: airway inflammation, CFTR, F508del, CFTR corrector, CFTR potentiator, CFTR rescue, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2021.628722/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/0684a12ec8d9405d9a3000c14aebce39Test

المؤلفون: Spano' V., Barreca M., Cilibrasi V., Genovese M., Renda M., Montalbano A., Galietta L. J. V., Barraja P.

المساهمون: Spano' V., Barreca M., Cilibrasi V., Genovese M., Renda M., Montalbano A., Galietta L.J.V., Barraja P.

مصطلحات موضوعية: CFTR, CFTR corrector, CFTR potentiator, cystic fibrosis, F508del-CFTR

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33652850; volume:26; issue:5; firstpage:1; lastpage:25; numberofpages:25; journal:MOLECULES; http://hdl.handle.net/10447/493064Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85102483302

الإتاحة: https://doi.org/10.3390/molecules26051275Test
http://hdl.handle.net/10447/493064Test

المؤلفون: Carla M. P. Ribeiro, Martina Gentzsch

المصدر: Cells; Volume 10; Issue 11; Pages: 3260

مصطلحات موضوعية: cystic fibrosis, CFTR, airway inflammation, CFTR corrector, CFTR potentiator, F508del rescue, primary bronchial epithelia

وصف الملف: application/pdf

العلاقة: Cellular Pathology; https://dx.doi.org/10.3390/cells10113260Test

الإتاحة: https://doi.org/10.3390/cells10113260Test

المؤلفون: Virginia Spanò, Marilia Barreca, Vincenzo Cilibrasi, Michele Genovese, Mario Renda, Alessandra Montalbano, Luis Juan Vicente Galietta, Paola Barraja

المصدر: Molecules; Volume 26; Issue 5; Pages: 1275

مصطلحات موضوعية: cystic fibrosis, CFTR, F508del-CFTR, CFTR corrector, CFTR potentiator

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules26051275Test

الإتاحة: https://doi.org/10.3390/molecules26051275Test

المؤلفون: Righetti G., Casale M., Tonelli M., Liessi N., Fossa P., Pedemonte N., Millo E., Cichero E.

المساهمون: Righetti, G., Casale, M., Tonelli, M., Liessi, N., Fossa, P., Pedemonte, N., Millo, E., Cichero, E.

مصطلحات موضوعية: CFTR modulator, CFTR potentiator, F508del CFTR, Molecular docking, Pharmacophore analyse, VX-770

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33291847; info:eu-repo/semantics/altIdentifier/wos/WOS:000602487700001; volume:13; firstpage:1; lastpage:28; numberofpages:28; journal:PHARMACEUTICALS; https://hdl.handle.net/11567/1034977Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85097526626

الإتاحة: https://doi.org/10.3390/ph13120445Test
https://hdl.handle.net/11567/1034977Test