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المؤلفون: Huijuan Jin, Dhulfiqar Ali Abed, Haifa Albanyan, Melanie Goldstein, Longqin Hu
المصدر: Acta Pharmaceutica Sinica B, Vol 5, Iss 4, Pp 285-299 (2015)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: vitamin E, tocopherols, AD, Alzheimer׳s disease, Direct inhibitors of protein–protein interaction, Review, medicine.disease_cause, HTS, high-throughput screening, GST, glutathione S-transferase, General Pharmacology, Toxicology and Pharmaceutics, GCL, glutamate-cysteine ligase, PD, Parkinson׳s disease, chemistry.chemical_classification, GPx, glutathione peroxidase, Chemistry, Nrf2, nuclear factor erythroid 2–related factor 2, NTR, N-terminal region, respiratory system, Small molecule, MD, molecular dynamics, Keap1, Kelch-like ECH-associated protein 1, TRX, thioredoxin, Biochemistry, CBP, cAMP response element binding (CREB) protein, H2O2, hydrogen peroxide, CDDO-Me, bardoxolone methyl, HO-1, heme-oxygenase-1, FP, fluorescence polarization, THIQ, tetrahydroisoquinoline, 1O2, singlet oxygen, CTR, C-terminal region, Keap1, PPI, protein–protein interaction, Protein domain, IVR, intervening region, ARE, antioxidant response element, SPR, surface plasmon resonance, CVD, cardiovascular disease, DGR, double glycine repeats, O2−, superoxide, OH·, hydroxyl radical, STZ, streptozotocin, Nrf2, Protein–protein interaction, RNS, reactive nitrogen species, Structure–activity relationships, ROS, reactive oxygen species, Downregulation and upregulation, ONO2−, peroxynitrate, SOD, superoxide dismutase, medicine, FITC, flurescein isothiocyanate, X-ray crystallography, NO, nitric oxide, NMR,, lcsh:RM1-950, Bach1, BTB and CNC homology 1, vitamin C, ascorbate, KEAP1, NQO1, NAD(P)H quinone oxidoreductase I, Enzyme, lcsh:Therapeutics. Pharmacology, COPD, chronic obstructive pulmonary disease, Oxidative stress, High throughput screening assays, BTB, broad complex, tramtrack and bric-a-brac, IBS, inflammatory bowel disease, Cysteine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e376506c73d1e50dafd120221447bd0aTest
http://www.sciencedirect.com/science/article/pii/S2211383515000829Test -
2Myeloid derived suppressor cells-An overview of combat strategies to increase immunotherapy efficacy
المؤلفون: Toos Daemen, Joyce M Lubbers, Hans W. Nijman, Oana Draghiciu
المصدر: Oncoimmunology
مصطلحات موضوعية: CD62L, L-selectin, TUMOR-BEARING MICE, MDSCs, myeloid-derived suppressor cells, STAT3, signal transducer and activator of transcription 3, medicine.medical_treatment, ARG1, arginase-1, ATRA, all-trans retinoic acid, PDE-5, phosphodiesterase type 5, Review, IMCs, immature myeloid cells, HNSCC, head and neck squamous cell carcinoma, law.invention, APCs, antigen presenting cells, CARCINOMA PATIENTS, iNOS2, inducible nitric oxid synthase 2, law, GM-CSF/CSF2, granulocyte monocyte colony stimulating factor, ANTITUMOR IMMUNITY, GSH, glutathione, TGFβ, transforming growth factor β, Immunology and Allergy, Cytotoxic T cell, JAK2, Janus kinase 2, IN-VIVO, TCR, T cell receptor, gemcitabine, IL-1β, interleukin 1 β, NSAID, nonsteroidal anti-inflammatory drugs, c-kit, Mast/stem cell growth factor receptor, all-trans retinoic acid, TNFα, tumor necrosis factor α, IL-6, interleukin 6, mRCC, metastatic renal cell carcinoma, CCL2, chemokine (C-C motif) ligand 2, Oncology, VEGFR, vascular endothelial growth factor receptor, Tregs, regulatory T cells, CDDO-Me, bardoxolone methyl, ESTABLISHED TUMORS, DCs, dendritic cells, WITHANIA-SOMNIFERA, medicine.drug, MMPs, metalloproteinases (e.g., MMP9), CTLs, cytotoxic T lymphocytes, ERK1/2, extracellular signal-regulated kinases, FoxP3, forkhead box P3, 5-Fluorouracil, Immunology, sunitinib therapeutic vaccination, IFNγ, interferon γ, CANCER-PATIENTS, CD8(+) T-CELLS, Biology, ODN, oligodeoxynucleotides, RNS, reactive nitrogen species, ROS, reactive oxygen species, In vivo, IL-4, interleukin 4, TAMs, tumor-associated macrophages, medicine, PGE2, prostaglandin E2, WA, withaferin A, GITR, anti-glucocorticoid tumor necrosis factor receptor, bisphosphonates, CXCL15, chemokine (C-X-C motif) ligand 15, Flt3, Fms-like tyrosine kinase 3, WRE, Withaferin somnifera, NO, nitric oxide, immune suppressive mechanisms, HLA, human leukocyte antigen, SCF, stem cell factor, IMMUNOSUPPRESSIVE ACTIVITY, HSCs, hematopoietic stem cells, Cancer, COX2, cyclooxygenase 2, Immunotherapy, NADPH, nicotinamide adenine dinucleotide phosphate-oxidase NK cells, natural killer cells, medicine.disease, myeloid-derived suppressor cells, HPV-16, human papillomavirus 16, ADAM17, metalloproteinase domain-containing protein 17, Gemcitabine, Blockade, TRANS-RETINOIC ACID, NOHA, N-hydroxy-L-Arginine, NAC, N-acetyl cysteine, Myeloid-derived Suppressor Cell, Suppressor, CXCL12, chemokine (C-X-C motif) ligand 12, 5-FU, 5-fluorouracil, HIF-1α, hypoxia inducible factor 1α, IL-10, interleukin 10, Myd88, myeloid differentiation primary response protein 88, ICT, 3, 5, 7-trihydroxy-4′-emthoxy-8-(3-hydroxy-3-methylbutyl)-flavone, IL-13, interleukin 13
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d066a21e4c242e158360b8a1aa115a0Test
https://pubmed.ncbi.nlm.nih.gov/25949858Test