المؤلفون: Chen, Xu-Qiao, Fang, Fang, Florio, Jazmin B, Rockenstein, Edward, Masliah, Eliezer, Mobley, William C, Rissman, Robert A, Wu, Chengbiao

المصدر: Traffic (Copenhagen, Denmark). 19(11)

مصطلحات موضوعية: Cells, Cultured, CHO Cells, Microtubules, Animals, Humans, Cricetulus, Rats, Brain-Derived Neurotrophic Factor, tau Proteins, Axonal Transport, Phosphorylation, Cricetinae, Cyclin-Dependent Kinase 5, Chaperonin Containing TCP-1, HEK293 Cells, TRiC/CCT chaperonin, axonal transport, hyperphosphorylation, tau, Aging, Neurodegenerative, Brain Disorders, Neurosciences, 1.1 Normal biological development and functioning, Underpinning research, Neurological, TRiC, CCT chaperonin, Biochemistry and Cell Biology, Medical Microbiology, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3rv1r2ntTest

المؤلفون: Kelly, John J., Tranter, Dale, Pardon, Els, Chi, Gamma, Kramer, Holger, Happonen, Lotta, Knee, Kelly M., Janz, Jay M., Steyaert, Jan, Bulawa, Christine, Paavilainen, Ville O., Huiskonen, Juha T., Yue, Wyatt W.

المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, Biosciences, Molecular and Integrative Biosciences Research Programme

مصطلحات موضوعية: CRYO-EM STRUCTURE, GROUP-II CHAPERONIN, EUKARYOTIC CHAPERONIN, CYTOSOLIC CHAPERONIN, CRYSTAL-STRUCTURE, ATP HYDROLYSIS, CCT CHAPERONIN, PROTEIN, MECHANISM, SUBUNIT, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: J.J.K. was supported by the Nuffield Department of Medicine DPhil Prize Studentship. The work by J.J.K. and W.W.Y. was also supported by funding from Pfizer Inc. J.J.K., G.C., and W.W.Y. were part of the Structural Genomics Consortium (Registered charity number 1097737) and acknowledged funding from the Wellcome Trust (092809/Z/10/Z). This project was also funded by the Academy of Finland consortium grant SEMMA (314669 to J.T.H., 314672 to V.O.P.). Cryo-EM was carried out with support of the Biocenter Finland and Instruct-HiLIFE cryo-EM core facility (University of Helsinki), Oxford Particle Imaging Centre (University of Oxford) and eBIC (Diamond Light Source, UK, visits EM20223-30 and EM20223-31 to J.T.H. and W. W. Yue). We thank B. Loflund and P. Laurinmaki (University of Helsinki), B. MacLean (University of Oxford), J. Radecke and A. Howe (eBIC) for technical assistance with cryo-EM experiments, and CSC - IT Center for Science, Finland, for computational resources. We acknowledge the support and the use of resources of Instruct-ERIC (PID6308 to E.P. and J.S.), part of the European Strategy Forum on Research Infrastructures (ESFRI), and the Research Foundation - Flanders (FWO) for the Nanobody discovery. Support from the Swedish National Infrastructure for Biological Mass Spectrometry (BioMS) and the SciLifeLab, Integrated Structural Biology platform is gratefully acknowledged (L.H.). We acknowledge N. Buys, E. Beke, A. Lundqvist and K. Willibal for the technical assistance during the Nanobody discovery and Nanobody workshop.; Kelly , J J , Tranter , D , Pardon , E , Chi , G , Kramer , H , Happonen , L , Knee , K M , Janz , J M , Steyaert , J , Bulawa , C , Paavilainen , V O , Huiskonen , J T & Yue , W W 2022 , ' Snapshots of actin and tubulin folding inside the TRiC chaperonin ' , Nature Structural and Molecular Biology , vol. 29 , pp. 420–429 . https://doi.org/10.1038/s41594-022-00755-1Test; ORCID: /0000-0002-0348-7323/work/156150865; http://hdl.handle.net/10138/347492Test; 775890eb-2294-46d8-bc1d-025f87fffee5; 000784657700001

الإتاحة: http://hdl.handle.net/10138/347492Test

المؤلفون: Joanna Zamel (11000393), Shon Cohen (11000396), Keren Zohar (11000399), Nir Kalisman (93191)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Immunology, Developmental Biology, Cancer, Inorganic Chemistry, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, CCT particle, study protein structures, sample simplification, 200 cross-links, CLMS, Mass Spectrometry, subunit arrangement, Situ Cross-Linking, Antibody-Based Protein Enrichment C., protein material, cell lysate, CCT chaperonin, target protein, mass spectrometry identification, protein systems, cell lysis, mass spectrometry analysis, cross-linked peptides, antibody

العلاقة: https://figshare.com/articles/journal_contribution/Facilitating_In_Situ_Cross-Linking_and_Mass_Spectrometry_by_Antibody-Based_Protein_Enrichment/14815460Test

الإتاحة: https://doi.org/10.1021/acs.jproteome.1c00269.s001Test

المؤلفون: Ying-Hsuan Wang, Zhao-Ying Ding, Ying-Ju Cheng, Cheng-Ting Chien, Min-Lang Huang

المصدر: Frontiers in Cellular Neuroscience, Vol 14 (2020)

مصطلحات موضوعية: CCT chaperonin, microtubule, dendrite morphogenesis, genetic screen, Drosophila, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fncel.2020.577315/fullTest; https://doaj.org/toc/1662-5102Test

الوصول الحر: https://doaj.org/article/9ed0c24f6d3e4d09a5659151d7ca5b91Test

المؤلفون: John J. Kelly, Dale Tranter, Els Pardon, Gamma Chi, Holger Kramer, Lotta Happonen, Kelly M. Knee, Jay M. Janz, Jan Steyaert, Christine Bulawa, Ville O. Paavilainen, Juha T. Huiskonen, Wyatt W. Yue

المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, Biosciences, Molecular and Integrative Biosciences Research Programme, Department of Bio-engineering Sciences, Structural Biology Brussels

المصدر: Nature Structural & Molecular Biology. 29:420-429

مصطلحات موضوعية: MECHANISM, PROTEIN, EUKARYOTIC CHAPERONIN, ATP HYDROLYSIS, CYTOSOLIC CHAPERONIN, GROUP-II CHAPERONIN, Structural Biology, SUBUNIT, CRYO-EM STRUCTURE, 1182 Biochemistry, cell and molecular biology, CRYSTAL-STRUCTURE, sense organs, CCT CHAPERONIN, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c6ef58fbb341764a444fd4085970edTest
https://doi.org/10.1038/s41594-022-00755-1Test

المؤلفون: Brackley, Karen I., Grantham, Julie

المصدر: Cell Stress & Chaperones, 2009 Jan 01. 14(1), 23-31.

الوصول الحر: https://www.jstor.org/stable/20456354Test

المؤلفون: Simona Vladimirova Antonova

المساهمون: Timmers, H.T.M., Heck, A.J.R., University Utrecht

مصطلحات موضوعية: quantitative proteomics, assembly, General transcription factor, CCT chaperonin, Eukaryotic transcription, TFIID, TAF1L, SAGA, Promoter, RNA polymerase II, macromolecular substances, Computational biology, Biology, SAGA complex, TAF1, Transcription (biology), LECA, evolution, TFIID, SAGA, quantitative proteomics, evolution, LECA, assembly, TAF1L, CCT chaperonin, biology.protein, Transcription factor II D

وصف الملف: image/pdf; text/plain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8b3351102c077ec427c90d1f10a6aaTest
https://dspace.library.uu.nl/handle/1874/400062Test

المؤلفون: Wang, Dan Yang, Kamuda, Kamila, Montoya, Guillermo, Mesa, Pablo

المساهمون: Mendillo, Marc Laurence, Pincus, David, ScherzShouval, Ruth

المصدر: Wang , D Y , Kamuda , K , Montoya , G & Mesa , P 2020 , The TRiC/CCT Chaperonin and Its Role in Uncontrolled Proliferation . in M L Mendillo , D Pincus & R ScherzShouval (eds) , HSF1 and Molecular Chaperones in Biology and Cancer . Springer , Advances in Experimental Medicine and Biology , vol. 1243 , pp. 21-40 . https://doi.org/10.1007/978-3-030-40204-4_2Test

مصطلحات موضوعية: Chaperonines, Molecular machines, Cell cycle, Protein folding, Allosterism, ATP hydrolysis, Protein-protein interaction, X-ray, cryoEM, ANAPHASE-PROMOTING COMPLEX, EUKARYOTIC CHAPERONIN, MOLECULAR CHAPERONE, CYTOPLASMIC CHAPERONIN, CYTOSOLIC CHAPERONIN, CCT CHAPERONIN, SACCHAROMYCES-CEREVISIAE, CONFORMATIONAL-CHANGES, CRYSTAL-STRUCTURE, LID CLOSURE

الإتاحة: https://doi.org/10.1007/978-3-030-40204-4_2Test
https://curis.ku.dk/portal/da/publications/the-triccctTest-chaperonin-and-its-role-in-uncontrolled-proliferation(21531f5e-d353-4492-9b5a-9d30d88e38ac).html

المؤلفون: Jiyuan, Chen, Kaveeta, Kaw, Hailong, Lu, Patricia M, Fagnant, Abhijnan, Chattopadhyay, Xue Yan, Duan, Zhen, Zhou, Shuangtao, Ma, Zhenan, Liu, Jian, Huang, Kristine, Kamm, James T, Stull, Callie S, Kwartler, Kathleen M, Trybus, Dianna M, Milewicz

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: actin folding, ACTA2, gene for smooth muscle α-actin, MRTF-A, myocardin-related transcription factor-A, Aortic Diseases, Mutation, Missense, SMC, smooth muscle cell, macromolecular substances, TIRF, total internal reflection fluorescence, Mice, SM, smooth muscle, RLC, regulatory light chain, Animals, Point Mutation, HTAD, heritable thoracic aortic disease, ACTA1, gene for skeletal muscle α-actin, Aorta, PE, phenylephrine, aortic disease, Actins, Mice, Inbred C57BL, L-NAME, l-Nω-nitroarginine methyl ester, smooth muscle actin, cardiovascular system, CCT, chaperonin-containing TCP-1, TAC, transverse aortic constriction, Chaperonin Containing TCP-1, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::8f72b0fe94460a8619be7f9e99c052b7Test
https://pubmed.ncbi.nlm.nih.gov/34600884Test

المؤلفون: Hyun Sook Pai, Joong Tak Yoon, Sumin Kim, Ho Seok Lee, Ilyeong Choi, Hee-Kyung Ahn

المصدر: Journal of Experimental Botany

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, genetic structures, Physiology, Protein subunit, Phosphatase, Arabidopsis, virus-induced gene silencing, macromolecular substances, Plant Science, Protein degradation, Microtubules, 01 natural sciences, Chaperonin, 03 medical and health sciences, Tubulin, PP4 catalytic subunit, Gene, biology, Arabidopsis Proteins, Chemistry, CCT chaperonin, Tap46, Protein phosphatase 2, biology.organism_classification, Research Papers, eye diseases, Cell biology, Repressor Proteins, enzymes and coenzymes (carbohydrates), TOR signaling pathway, 030104 developmental biology, biological sciences, tubulin biogenesis, bacteria, Protein folding, Growth and Development, sense organs, 010606 plant biology & botany

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47740c448be23b02ef260ded95e79680Test
https://doi.org/10.1093/jxb/erz099Test