يعرض 1 - 10 نتائج من 756 نتيجة بحث عن '"CCR5 receptor antagonist"', وقت الاستعلام: 1.29s تنقيح النتائج
  1. 1
    Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc

    المؤلفون: Zhufang Li, Peter Ackerman, Nannan Zhou, Margaret Gartland, Max Lataillade, Mark I. Cockett, Rose Ronald, Mark Krystal, Jagadish Beloor

    المصدر: AIDS (London, England)

    مصطلحات موضوعية: maraviroc, Anti-HIV Agents, Immunology, MOTIVATE, HIV Infections, CCR5 receptor antagonist, HIV Envelope Protein gp120, Pharmacology, chemistry.chemical_compound, Basic Science, Cyclohexanes, Viral entry, Drug Resistance, Viral, Consensus sequence, medicine, Humans, Immunology and Allergy, fostemsavir, Cross-resistance, Maraviroc, chemistry.chemical_classification, BRIGHTE, Ibalizumab, Antibodies, Monoclonal, ibalizumab, temsavir, Amino acid, Infectious Diseases, Fostemsavir, chemistry, CCR5 Receptor Antagonists, cross-resistance, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da40070bb29ca8112803b1156c99bafTest
    https://doi.org/10.1097/qad.0000000000003097Test


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  2. 2
    In classical Hodgkin lymphoma the combination of the CCR5 antagonist maraviroc with trabectedin synergizes, enhances DNA damage and decreases three-dimensional tumor-stroma heterospheroid viability

    المؤلفون: Cinzia Borghese, Naike Casagrande, Donatella Aldinucci

    المصدر: Haematologica

    مصطلحات موضوعية: Receptors, CCR5, business.industry, DNA damage, HIV Infections, Hematology, CCR5 receptor antagonist, Hodgkin Disease, Maraviroc, chemistry.chemical_compound, chemistry, CCR5 Receptor Antagonists, Classical Hodgkin lymphoma, Cancer research, Humans, Medicine, Letters to the Editor, business, Tumor stroma, Trabectedin, DNA Damage, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e00e2babe397935e62690459a21209dTest
    https://doi.org/10.3324/haematol.2021.279389Test


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  3. 3
    Co-receptor signaling in the pathogenesis of neuroHIV

    المؤلفون: E. A. Nickoloff-Bybel, Olimpia Meucci, L. Festa, P. J. Gaskill

    المصدر: Retrovirology, Vol 18, Iss 1, Pp 1-35 (2021)
    Retrovirology

    مصطلحات موضوعية: Receptors, CXCR4, Co-receptor, Receptors, CCR5, Context (language use), HIV Infections, CCR5 receptor antagonist, Review, Biology, chemistry.chemical_compound, Mice, Receptors, HIV, Virology, Animals, Humans, Neuroinflammation, Maraviroc, NeuroHIV, CXCR4, Clinical Trials as Topic, virus diseases, HIV, HIV envelope protein, RC581-607, Signaling, Infectious Diseases, chemistry, CCR5 Receptor Antagonists, Neuroinflammatory Diseases, HIV-1, Neuropathogenesis, Signal transduction, Immunologic diseases. Allergy, Neuroscience, CCR5, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e72066a6afb9bd64c2b48ead2ebcf52Test
    https://doaj.org/article/32091bbc047e4aadaf828954f9f1d18cTest


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  4. 4
    A 'Two-Birds-One-Stone' Approach toward the Design of Bifunctional Human Immunodeficiency Virus Type 1 Entry Inhibitors Targeting the CCR5 Coreceptor and gp41 N-Terminal Heptad Repeat Region

    المؤلفون: Yang Liu, Lu Lu, Chao Wang, Xinling Wang, Jing Pu, Jiahui Li, Shibo Jiang, Qing X. Li, Huan Wang

    المصدر: Journal of Medicinal Chemistry. 64:11460-11471

    مصطلحات موضوعية: Receptors, CCR5, Anti-HIV Agents, viruses, Peptide, CCR5 receptor antagonist, Gp41, Structure-Activity Relationship, Chimera (genetics), chemistry.chemical_compound, Viral envelope, Drug Discovery, Humans, Bifunctional, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, virus diseases, Virus Internalization, Virology, HIV Envelope Protein gp41, Heptad repeat, chemistry, Drug Design, CCR5 Receptor Antagonists, HIV-1, Molecular Medicine, Pharmacophore

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d036ce3d5a8e4220a2f31260dce28780Test
    https://doi.org/10.1021/acs.jmedchem.1c00781Test


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  5. 5
    Differential utilization of CD4+ by transmitted/founder and chronic envelope glycoproteins in a MSM HIV-1 subtype B transmission cluster

    المؤلفون: Olivia Blake, Denys Brand, Nicolas Bellini, Emmanuelle Roch, Fabrizio Mammano, Alain Moreau, Martine Braibant, Julie Migraine, Jean-Christophe Plantier, Mélanie Bouvin-Pley, Marie Leoz

    المساهمون: Morphogénèse et antigénicité du VIH et du virus des Hépatites (MAVIVH - U1259 Inserm - CHRU Tours ), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Groupe de Recherche sur les Antimicrobiens et les Micro-Organismes (GRAM 1.0), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), CHU Rouen, Normandie Université (NU), Université de Montréal (UdeM), Institut de Recherches Cliniques de Montréal (IRCM), Génétique et Ecologie des Virus, Génétique des Virus et Pathogénèse des Maladies Virales, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mammano, Fabrizio, Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7)

    المصدر: AIDS
    AIDS, Lippincott, Williams & Wilkins, 2020, 34 (15), pp.2187-2200. ⟨10.1097/qad.0000000000002690⟩
    AIDS. Official journal of the international AIDS Society
    AIDS. Official journal of the international AIDS Society, 2020, 34 (15), pp.2187-2200. ⟨10.1097/qad.0000000000002690⟩

    مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, [SDV]Life Sciences [q-bio], Immunology, MESH: Glycoproteins, HIV Infections, Context (language use), Viral quasispecies, CCR5 receptor antagonist, Biology, HIV transmission cluster, MESH: HIV-1, MESH: Homosexuality, Male, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Viral Envelope Proteins, Interferon, Genotype, medicine, Humans, Immunology and Allergy, 030212 general & internal medicine, Homosexuality, Male, Glycoproteins, Maraviroc, Infectivity, MESH: Humans, Transmission (medicine), envelope glycoproteins, MESH: CD4-Positive T-Lymphocytes, MESH: HIV Infections, Virology, MESH: Male, 3. Good health, [SDV] Life Sciences [q-bio], 030104 developmental biology, Infectious Diseases, chemistry, MESH: Viral Envelope Proteins, HIV-1, CD4 þ binding, genetic bottleneck, medicine.drug

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92c89e194baabacf613baf0e15f0daeTest
    https://doi.org/10.1097/qad.0000000000002690Test


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  6. 6
    CCR5 antagonist treatment inhibits vascular injury by regulating NADPH oxidase 1

    المؤلفون: Shubhnita Singh, Thiago Bruder-Nascimento, Eric J. Belin de Chantemèle, Ariane Bruder-Nascimento

    المصدر: Biochem Pharmacol

    مصطلحات موضوعية: Male, Chemokine, Receptors, CCR5, Myocytes, Smooth Muscle, CCR5 receptor antagonist, Pharmacology, Biochemistry, CCL5, Article, Muscle, Smooth, Vascular, Maraviroc, Chemokine receptor, Cell Movement, Animals, Chemokine CCL5, Cells, Cultured, biology, Chemistry, virus diseases, NADPH Oxidase 1, NOX4, Cell migration, Vascular System Injuries, Recombinant Proteins, Rats, Mice, Inbred C57BL, Gene Expression Regulation, NOX1, CCR5 Receptor Antagonists, cardiovascular system, biology.protein

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d8ba4fe177e9d29af9c4cd8f1afcc1Test
    https://europepmc.org/articles/PMC8914050Test/


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  7. 7
    CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG mice

    المؤلفون: Georgette D. Kanmogne, JoEllyn M McMillan, Biju Bhargavan, Shawna M. Woollard

    المصدر: Molecular Neurodegeneration
    Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-23 (2021)

    مصطلحات موضوعية: Amyloid beta, LRP1, Receptor for Advanced Glycation End Products, Tau phosphorylation, CCR5 receptor antagonist, Pharmacology, Neuronal damage, Blood–brain barrier, Maraviroc, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Alzheimer Disease, Mice, Inbred NOD, NSG mice, medicine, Animals, RC346-429, Molecular Biology, Amyloid beta-Peptides, biology, Human brain microvascular endothelial cells, business.industry, RC952-954.6, Endothelial Cells, Human brain, RAGE, medicine.anatomical_structure, chemistry, Geriatrics, Blood-Brain Barrier, Blood-brain barrier injury, Humanized mouse, biology.protein, HIV-1, Neurology (clinical), Neurology. Diseases of the nervous system, NeuN, Amyloid-beta, business, Monocytes-derived macrophages, CCR5, Research Article

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd86f9d13c0c921e76ab89ef58320066Test
    http://europepmc.org/articles/PMC8607567Test


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  8. 8
    Studies on the IC50 of Metabolically Stable 1-(3,3-diphenylpropyl)- piperidinyl Amides and Ureas as Human CCR5 Receptor Antagonists Based on QSAR

    المؤلفون: Zhao Yutao, Tian Dongdong, Ouyang Jing, Liu Xiaoqian, Si Hongzong, Wang Yan, Xu Shanyu

    المصدر: Letters in Drug Design & Discovery. 17:1036-1046

    مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, Quantitative structure–activity relationship, 030104 developmental biology, 0302 clinical medicine, Stereochemistry, Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, CCR5 receptor antagonist, IC50, 030217 neurology & neurosurgery

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a9cd85df49ecd6f3ab9c7cdb50bdf7aaTest
    https://doi.org/10.2174/1570180817666200320105725Test


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  9. 9
    CCR5 inhibitor as novel acute graft versus host disease prophylaxis in children and young adults undergoing allogeneic stem cell transplant: results of the phase II study

    المؤلفون: J.J. Bleesing, Adam Lane, Michael B. Jordan, Pooja Khandelwal, Mary Christa Krupski, Tsuyoshi Fukuda, Adam S. Nelson, Parinda A. Mehta, Ashley Teusink-Cross, Angela D. M. Kashuba, Kasiani C. Myers, Javier El-Bietar, Sharat Chandra, Michael Grimley, Rebecca A. Marsh, Stella M. Davies

    المصدر: Bone Marrow Transplantation. 55:1552-1559

    مصطلحات موضوعية: Transplantation, medicine.medical_specialty, business.industry, Phases of clinical research, Hematology, CCR5 receptor antagonist, Gastroenterology, Calcineurin, 03 medical and health sciences, chemistry.chemical_compound, surgical procedures, operative, 0302 clinical medicine, chemistry, immune system diseases, 030220 oncology & carcinogenesis, Internal medicine, Pharmacodynamics, medicine, Methotrexate, Young adult, Adverse effect, business, 030215 immunology, medicine.drug, Maraviroc

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7a73e8ade464104d951daf5f3e234013Test
    https://doi.org/10.1038/s41409-020-0888-3Test


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  10. 10
    Clinical significance of chemokine receptor antagonists

    المؤلفون: Guangdi Li, Erik De Clercq, Miao Miao

    المصدر: Expert Opinion on Drug Metabolism & Toxicology. 16:11-30

    مصطلحات موضوعية: Receptors, CXCR4, CCR2, Chemokine, Receptors, CCR4, Receptors, CCR5, Receptors, CCR2, CCR4, CCR5 receptor antagonist, Pharmacology, Toxicology, 030226 pharmacology & pharmacy, CXCR4, 03 medical and health sciences, Chemokine receptor, 0302 clinical medicine, Drug Development, Mogamulizumab, Animals, Humans, Medicine, CXCR4 antagonist, biology, business.industry, General Medicine, 030220 oncology & carcinogenesis, biology.protein, Receptors, Chemokine, business, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6ccb11ad32542a99ebb3d97086dde5Test
    https://doi.org/10.1080/17425255.2020.1711884Test


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