-
1دورية أكاديمية
المؤلفون: Kim Nguyen, Turnee N. Malik, John C. Chaput
المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
-
2دورية أكاديمية
المؤلفون: Adriana Lozoya-Colinas, Yutong Yu, John C. Chaput
مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Biotechnology, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vitro evolution strategies, round screening approach, receptor binding domain, highly parallelizable path, detailed biochemical characterization, parallelized library screening, library design combinations, binding affinity values, de novo discovery, sequence library, affinity sequences, work establishes, viable route, therapeutic targets, therapeutic aptamers, severely restricts, s1 protein, may offer, including disease, enhancing chemotypes, conventional selex, associated proteins
الإتاحة: https://doi.org/10.1021/jacs.3c09497.s001Test
https://figshare.com/articles/journal_contribution/Functionally_Enhanced_XNA_Aptamers_Discovered_by_Parallelized_Library_Screening/24560508Test -
3دورية أكاديمية
المؤلفون: Nicholas Chim, Roman A. Meza, Anh M. Trinh, Kefan Yang, John C. Chaput
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
-
4دورية أكاديمية
المؤلفون: Yajun Wang, Arlene K. Ngor, Ali Nikoomanzar, John C. Chaput
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
-
5دورية أكاديمية
المؤلفون: Cailen M. McCloskey (6203723), Qingfeng Li (1524259), Eric J. Yik (7228490), Nicholas Chim (203955), Arlene K. Ngor (7228487), Esau Medina (10867876), Ivan Grubisic (11655146), Lance Co Ting Keh (11655149), Ryan Poplin (401807), John C. Chaput (29064)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, side chain modifications, rate binding kinetics, natural genetic systems, kinetic measurements reveal, include functional groups, threofuranosyl nucleic acid, nucleic acids, vitro <, uniformly equipped, transition aptamers, therapeutic agents, structural properties, laboratory tools, human diseases, findings expand, evolvable non
-
6دورية أكاديمية
المؤلفون: Esau Medina (10867876), Eric J. Yik (7228490), Piet Herdewijn (8001), John C. Chaput (29064)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Mental Health, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Bst DNA polymerase, reverse-transcribe XNA polymers, acid, FANA, transcriptase activity, XNA synthesis increase, HNA, substrate specificity, Laboratory-Evolved XNA Polymerases, PMT, TNA, ANA, RNA, XNA polymerases
-
7دورية أكاديمية
المؤلفون: Kefan Yang (9494782), John C. Chaput (29064)
مصطلحات موضوعية: Medicine, Molecular Biology, Immunology, Cancer, Plant Biology, Virology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, RNA-Encoded Viral Nucleic, Analyte Reporter, SARS-CoV -2 detection, acid alternative, assay time, COVID -19, function, analyte preamplification, detection limit, Detection System, acid detection platform, pathogen detection, flow readout modalities, REVEALR, acid detection, 1 h, equivalent CRISPR-based approaches, multicomponent XNA-based, Multicomponent XNAzyme-Based Nucleic, disease diagnosis
-
8دورية أكاديمية
المؤلفون: Kim Nguyen (424295), Yajun Wang (197421), Whitney E. England (10346575), John C. Chaput (29064), Robert C. Spitale (2350243)
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Cancer, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, nucleotide mutations, XNAzyme X 10-23, protein level, allele-specific mRNA sequences, 12V, Catalytically Efficient XNAzyme The., Allele-Specific RNA Knockdown, Biologically Stable, disease-causing mutations, molecule therapeutics, oncogenic KRAS
-
9دورية أكاديمية
المؤلفون: Turnee N. Malik, John C. Chaput
المصدر: Current Research in Chemical Biology, Vol 1, Iss , Pp 100012- (2021)
مصطلحات موضوعية: Xeno-nucleic acids (XNAs), Xenobiotic nucleic acids, TNA, FANA, XNAzyme, Biochemistry, QD415-436
العلاقة: http://www.sciencedirect.com/science/article/pii/S2666246921000124Test; https://doaj.org/toc/2666-2469Test; https://doaj.org/article/49b28ea626144342ace684ccbf4ef929Test
الإتاحة: https://doi.org/10.1016/j.crchbi.2021.100012Test
https://doaj.org/article/49b28ea626144342ace684ccbf4ef929Test -
10
المؤلفون: T. Ho, S. Shrivastava, A. MacPherson, L. Kozel, J. Camera, J. Perkins, C. Chaput, A. Thakar, C. Venegas, S. Svenningsen, J. Wald
المصدر: B22. NEW TREATMENTS AND NOVEL TARGETS FOR COPD AND ALPHA-1.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::54e9a8afe4adb65616b9c5bdec1b6d6bTest
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2843Test