المؤلفون: Heyes, Elizabeth (University of Veterinary Medicine Vienna), Porse, Bo T. (Copenhagen University Hospital / University of Copenhagen), D'Altri, Teresa (Copenhagen University Hospital / University of Copenhagen), Pundhir, Sachin (Copenhagen University Hospital / University of Copenhagen), Rzepa, Edwin (University of Veterinary Medicine Vienna), Schuster, Mikkel B. (Copenhagen University Hospital / University of Copenhagen), Eder, Thomas (University of Veterinary Medicine Vienna), Manhart, Gabriele (University of Veterinary Medicine Vienna), Wilhelmson, Anna S. (Copenhagen University Hospital / University of Copenhagen), Wenzel, Anne (Copenhagen University Hospital / University of Copenhagen), Grebien, Florian (University of Veterinary Medicine Vienna), Haferlach, Torsten (Munich Leukemia Laboratory), Schwaller, Jürg (University Children's Hospital Basel), Meggendorfer, Manja (Munich Leukemia Laboratory), Schoof, Erwin M. (Technical University of Denmark), Woessmann, Jakob (Technical University of Denmark), Gentil, Coline (Copenhagen University Hospital / University of Copenhagen), Frank, Anne-Katrine (Copenhagen University Hospital / University of Copenhagen)

المصدر: Nature Communications 14(1) (2023)

مصطلحات موضوعية: Hematopoietic Stem, C/Ebp-Alpha, Mutations Result, Read Alignment, Gene, Evi1, Aml, Transcription, Reveals, Mouse

وصف الملف: application/pdf

العلاقة: isPartOf:https://phaidra.vetmeduni.ac.at/o:605Test[Publications / University of Veterinary Medicine Vienna]; https://phaidra.vetmeduni.ac.at/o:2621Test

الإتاحة: https://doi.org/10.1038/s41467-023-41927-xTest
https://phaidra.vetmeduni.ac.at/o:2621Test

المؤلفون: Madsen, Maria Stahl, Broekema, Marjoleine F., Madsen, Martin Rønn, Koppen, Arjen, Borgman, Anouska, Grawe, Cathrin, Thomsen, Elisabeth G. K., Westland, Denise, Kranendonk, Mariette E. G., Koerkamp, Marian Groot, Hamers, Nicole, Bonvin, Alexandre M. J. J., Pittol, Jose M. Ramos, Natarajan, Kedar Nath, Kersten, Sander, Holstege, Frank C. P., Monajemi, Houshang, van Mil, Saskia W. C., Vermeulen, Michiel, Kragelund, Birthe B., Cassiman, David, Mandrup, Susanne, Kalkhoven, Eric

المصدر: Madsen , M S , Broekema , M F , Madsen , M R , Koppen , A , Borgman , A , Grawe , C , Thomsen , E G K , Westland , D , Kranendonk , M E G , Koerkamp , M G , Hamers , N , Bonvin , A M J J , Pittol , J M R , Natarajan , K N , Kersten , S , Holstege , F C P , Monajemi , H , van Mil , S W C , Vermeulen , M , Kragelund , B B ....

مصطلحات موضوعية: RECEPTOR-GAMMA, LIPOPROTEIN-LIPASE, GENETIC-VARIATION, ZINC-FINGER, C/EBP-ALPHA, BINDING, DNA, TRANSCRIPTION, ELEMENTS, RXR

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/s41467-022-34766-9Test
https://curis.ku.dk/portal/da/publications/ppar-lipodystrophy-mutants-reveal-intermolecular-interactions-required-for-enhancer-activationTest(b7234bb1-4273-4ad1-9e45-d0cd40918db9).html
https://curis.ku.dk/ws/files/329441901/s41467_022_34766_9.pdfTest

المؤلفون: Uemasu, Kiyoshi, 上桝, 潔, ウエマス, キヨシ

المساهمون: 伊達, 洋至, 萩原, 正敏, 松田, 道行

مصطلحات موضوعية: COPD, C/EBP-alpha, small airway injury, alveolar attachments, emphysema, LEKTI

وصف الملف: application/pdf; text/html

الوصول الحر: https://ndlsearch.ndl.go.jp/books/R100000039-I11583268Test

Degree: 博士(医学) -- Doctor of Medical Science -- 京都大学

المؤلفون: Caiment, F., Wolters, J., Smit, E., Schrooders, Y., Kleinjans, J., van den Beucken, T.

المصدر: Caiment , F , Wolters , J , Smit , E , Schrooders , Y , Kleinjans , J & van den Beucken , T 2020 , ' Valproic acid promotes mitochondrial dysfunction in primary human hepatocytes in vitro; impact of C/EBPα-controlled gene expression ' , Archives of Toxicology , vol. 94 , no. 10 , pp. 3463-3473 . https://doi.org/10.1007/s00204-020-02835-xTest

مصطلحات موضوعية: ccaat/enhancer-binding protein alpha (c/ebp alpha), exposure, glutathione, hepatotoxicity, homeostasis, induced liver steatosis, lentiviral shrna, mechanisms, oxygen consumption, phosphorylation, primary human hepatocytes, rna interference, steatosis, transcription factors, transcriptomics, valproic acid

الإتاحة: https://doi.org/10.1007/s00204-020-02835-xTest
https://cris.maastrichtuniversity.nl/en/publications/9ab1a694-19a2-48d7-b579-6a5b1d5c985fTest

المؤلفون: Bradford, Stephen T., Nair, Shalima S., Statham, Aaron L., van Dijk, Susan J., Peters, Timothy J., Anwar, Firoz, French, Hugh J., von Martels, Julius Z. H., Sutcliffe, Brodie, Maddugoda, Madhavi P., Peranec, Michelle, Varinli, Hilal, Arnoldy, Rosanna, Buckley, Michael, Ross, Jason P., Zotenko, Elena, Song, Jenny Z., Stirzaker, Clare, Bauer, Denis C., Qu, Wenjia, Swarbrick, Michael M., Lutgers, Helen L., Lord, Reginald V., Samaras, Katherine, Molloy, Peter L., Clark, Susan J.

المصدر: Bradford , S T , Nair , S S , Statham , A L , van Dijk , S J , Peters , T J , Anwar , F , French , H J , von Martels , J Z H , Sutcliffe , B , Maddugoda , M P , Peranec , M , Varinli , H , Arnoldy , R , Buckley , M , Ross , J P , Zotenko , E , Song , J Z , Stirzaker , C , Bauer , D C , Qu , W , Swarbrick , M M , ....

مصطلحات موضوعية: HUMAN ADIPOSE-TISSUE, BODY-MASS INDEX, EPIGENOMIC ANALYSIS, C/EBP-ALPHA, FAT, OBESITY, METHYLATION, CTBP2, RISK, MECHANISMS

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/b3ee8d95-8caf-4e20-86f2-813af45c6669Test

الإتاحة: https://doi.org/10.1038/s41598-019-45777-wTest
https://hdl.handle.net/11370/b3ee8d95-8caf-4e20-86f2-813af45c6669Test
https://research.rug.nl/en/publications/b3ee8d95-8caf-4e20-86f2-813af45c6669Test
https://pure.rug.nl/ws/files/91113176/Methylome_and_transcriptome_maps_of_human_visceral_and_subcutaneous_adipocytes_reveal_key_epigenetic_differences_at_developmental_genes.pdfTest

المؤلفون: Zhou, J, Li, H, Xia, X, Herrera, A, Pollock, N, Reebye, V, Sodergren, MH, Dorman, S, Littman, BH, Doogan, D, Huang, K-W, Habib, R, Blakey, D, Habib, NA, Rossi, JJ

المصدر: 1016 ; 999

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biotechnology & Applied Microbiology, Genetics & Heredity, Medicine, Research & Experimental, Research & Experimental Medicine, BINDING-PROTEIN-ALPHA, RAW 264.7 CELLS, NF-KAPPA-B, C/EBP-ALPHA, HEPATOCELLULAR-CARCINOMA, RHEUMATOID-ARTHRITIS, DOWN-REGULATION, EXPRESSION, INFLAMMATION, MOUSE, MTL-CEBPA, anti-inflammation, humanized mice, monocytes, saRNA, small activating RNA, Animals, Anti-Inflammatory Agents, CCAAT-Enhancer-Binding Proteins

العلاقة: Molecular Therapy; http://hdl.handle.net/10044/1/80680Test

الإتاحة: https://doi.org/10.1016/j.ymthe.2019.02.018Test
http://hdl.handle.net/10044/1/80680Test

المؤلفون: Jiazhen Wang, Peipei Wang, Tiantian Zhang, Zhuying Gao, Jing Wang, Mengdie Feng, Rong Yin, Haojian Zhang

مصطلحات موضوعية: ACUTE MYELOGENOUS LEUKEMIA, Acute myeloid leukemia, C/EBP-ALPHA, DNMT3A, GENE-EXPRESSION, Hematology, HEMATOPOIETIC-STEM, INTERLEUKIN-3 RECEPTOR, Leukemia stem cell, Life Sciences & Biomedicine, Maintenance, Molecular mechanisms, OXIDATIVE-PHOSPHORYLATION, RECEPTOR-ALPHA CHAIN, Science & Technology, SELF-RENEWAL, Stemness, TRANSCRIPTION FACTORS

العلاقة: http://hdl.handle.net/10779/DRO/DU:23797029.v2Test; https://figshare.com/articles/journal_contribution/Molecular_mechanisms_for_stemness_maintenance_of_acute_myeloid_leukemia_stem_cells/23797029Test

الإتاحة: http://hdl.handle.net/10779/DRO/DU:23797029.v2Test
https://figshare.com/articles/journal_contribution/Molecular_mechanisms_for_stemness_maintenance_of_acute_myeloid_leukemia_stem_cells/23797029Test

المؤلفون: Reckzeh, Kristian, Cammenga, Jörg

المصدر: International Journal of Hematology. 91(4):557-568

مصطلحات موضوعية: differentiation, Myeloid, C/EBP alpha, Transcription factor, AML, Leukemia, Bi-allelic mutation, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Cell- och molekylärbiologi, Medical and Health Sciences, Basic Medicine, Cell and Molecular Biology

الوصول الحر: https://lup.lub.lu.se/record/1618587Test
http://www.ncbi.nlm.nih.gov/pubmed/20422469?dopt=AbstractTest
http://dx.doi.org/10.1007/s12185-010-0573-1Test

المؤلفون: Guo, Michael H., Nandakumar, Satish K., Ulirsch, Jacob C., Zekavat, Seyedeh M., Buenrostro, Jason D., Natarajan, Pradeep, Salem, Rany M., Chiarle, Roberto, Mitt, Mario, Kals, Mart, Pärn, Kalle, Fischer, Krista, Milani, Lili, Magi, Reedik, Palta, Priit, Gabriel, Stacey B., Metspalu, Andres, Lander, Eric S., Kathiresan, Sekar, Hirschhorn, Joel N., Esko, Tonu, Sankaran, Vijay G.

المساهمون: Institute for Molecular Medicine Finland, Genomics of Neurological and Neuropsychiatric Disorders

مصطلحات موضوعية: genome sequencing, GWAS, basophils, hematopoiesis, CEBPA, INFLAMMATORY-BOWEL-DISEASE, RARE-VARIANT ASSOCIATION, FETAL-HEMOGLOBIN LEVELS, COPY NUMBER VARIATIONS, BLOOD-CELL TRAITS, WIDE ASSOCIATION, MAST-CELL, GENETIC-VARIATION, C/EBP-ALPHA, PARTITIONING HERITABILITY, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: We thank members of the V.G.S. and J.N.H. Laboratories, as well as the Estonian Genome Center, and numerous colleagues for valuable comments and discussions. This work was supported by National Institutes of Health Grants R01 DK103794, R33 HL120791 (to V.G.S.), and R01 DK075787 (to J.N.H.). P.P. was funded by the Nordic Information for Action eScience Center by NordForsk (Project 62721). The Estonian Genome Center was supported by the Estonian Research Council (PerMed I; IUT20-60); European Union H2020 Grants 692145, 676550, and 654248; and the European Union through the European Regional Development Fund (GENTRANSMED).; Guo , M H , Nandakumar , S K , Ulirsch , J C , Zekavat , S M , Buenrostro , J D , Natarajan , P , Salem , R M , Chiarle , R , Mitt , M , Kals , M , Pärn , K , Fischer , K , Milani , L , Magi , R , Palta , P , Gabriel , S B , Metspalu , A , Lander , E S , Kathiresan , S , Hirschhorn , J N , Esko , T & Sankaran , V G 2017 , ' Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 114 , no. 3 , pp. E327-E336 . https://doi.org/10.1073/pnas.1619052114Test; ORCID: /0000-0001-9320-7008/work/30434482; 85009756476; 61ab282e-bfde-410f-970c-2208c642a2d4; http://hdl.handle.net/10138/232542Test; 000392095800009

الإتاحة: http://hdl.handle.net/10138/232542Test

المؤلفون: Langabeer, Stephen E., Preston, Lisa, Kelly, Johanna, Goodyer, Matt, Elhassadi, Ezzat, Hayat, Amjad

مصطلحات موضوعية: acute myeloid-leukemia, trans-retinoic acid, complete remission, c/ebp-alpha, mutations, disease, rearrangements, patient, genes, cells

العلاقة: Case Reports in Hematology; Langabeer, Stephen E. Preston, Lisa; Kelly, Johanna; Goodyer, Matt; Elhassadi, Ezzat; Hayat, Amjad (2017). Molecular profiling: a case of zbtb16-rara acute promyelocytic leukemia. Case Reports in Hematology; 2090-6560,2090-6579; http://hdl.handle.net/10379/12375Test

الإتاحة: https://doi.org/10.1155/2017/7657393Test
http://hdl.handle.net/10379/12375Test