المؤلفون: Wigger, Leonore, Barovic, Marko, Brunner, Andreas-David, Marzetta, Flavia, Schöniger, Eyke, Mehl, Florence, Kipke, Nicole, Friedland, Daniela, Burdet, Frederic, Kessler, Camille, Lesche, Mathias, Thorens, Bernard, Bonifacio, Ezio, Legido-Quigley, Cristina, Barbier Saint Hilaire, Pierre, Delerive, Philippe, Dahl, Andreas, Klose, Christian, Gerl, Mathias J., Simons, Kai, Aust, Daniela, Weitz, Jürgen, Distler, Marius, Schulte, Anke M., Mann, Matthias, Ibberson, Mark, Solimena, Michele

مصطلحات موضوعية: lipids, type 2 diabetes (T2D), pancreatic islets, multi-omics analysis, Lipide, Typ-2-Diabetes (T2D), Pankreasinseln, Multi-omics-Analyse, info:eu-repo/classification/ddc/610, ddc:610

العلاقة: info:eu-repo/grantAgreement/European Commission/H2020 - IMI2-RIA/115881//Assessing risk and progression of prediabetes and type 2 diabetes to enable disease modification/RHAPSODY

الإتاحة: https://tud.qucosa.de/id/qucosa%3A77166Test
https://tud.qucosa.de/api/qucosa%3A77166/attachment/ATT-0Test/

المؤلفون: Jones, Amanda K., Bajrami, Besnik, Campbell, Morgan K., Erzurumluoglu, Abdullah Mesut, Guo, Qiusha, Chen, Hongxing, Zhang, Xiaomei, Zeveleva, Svetlana, Kvaskoff, David, Brunner, Andreas-David, Muller, Stefanie, Gathey, Vasudha, Dave, Rajvee M., Tanner, James W., Rixen, Sophia, Struwe, Michel A., Phoenix, Kathryn, Klumph, Kaitlyn J., Robinson, Heather, Veyel, Daniel, Muller, Annkatrin, Noyvert, Boris, Bartholdy, Boris Alexander, Steixner-Kumar, Agnes A., Stutzki, Jan, Drichel, Dmitriy, Omland, Steffen, Sheehan, Ryan, Hill, Jon, Bretschneider, Tom, Gottschling, Dirk, Scheidig, Axel J., Clement, Bernd, Giera, Martin, Ding, Zhihao, Broadwater, John, Warren, Curtis R.

المصدر: Hepatology Communications ; volume 8, issue 5 ; ISSN 2471-254X

الإتاحة: https://doi.org/10.1097/hc9.0000000000000365Test

المؤلفون: Neukam, Martin, Sala, Pia, Brunner, Andreas-David, Ganß, Katharina, Palladini, Alessandra, Grzybek, Michal, Topcheva, Oleksandra, Vasiljević, Jovana, Broichhagen, Johannes, Johnsson, Kai, Kurth, Thomas, Mann, Matthias, Coskun, Ünal, Solimena, Michele

المساهمون: EFPIA, German Israeli Foundation for Scientific Research and Development, Swiss State Secretariat for Education Research and Innovation

المصدر: Cell Reports ; volume 43, issue 3, page 113836 ; ISSN 2211-1247

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.celrep.2024.113836Test
https://api.elsevier.com/content/article/PII:S2211124724001645?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2211124724001645?httpAccept=text/plainTest

المؤلفون: Chen, Jin, Brunner, Andreas-David, Cogan, J Zachery, Nuñez, James K, Fields, Alexander P, Adamson, Britt, Itzhak, Daniel N, Li, Jason Y, Mann, Matthias, Leonetti, Manuel D, Weissman, Jonathan S

المصدر: Science. 367(6482)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Prevention, Biodefense, Vaccine Related, Human Genome, Biotechnology, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, CRISPR-Cas Systems, Humans, Open Reading Frames, Operon, Peptides, Protein Biosynthesis, RNA, Messenger, Ribosomes, Transcriptome, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/96m1n5z5Test

المؤلفون: Mund, Andreas, Coscia, Fabian, Kriston, Andras, Hollandi, Reka, Kovacs, Ferenc, Brunner, Andreas-David, Migh, Ede, Schweizer, Lisa, Santos, Alberto, Bzorek, Michael, Naimy, Soraya, Rahbek-Gjerdrum, Lise Mette, Dyring-Andersen, Beatrice, Bulkescher, Jutta, Lukas, Claudia, Eckert, Mark Adam, Lengyel, Ernst, Gnann, Christian, Lundberg, Emma, Horvath, Peter, Mann, Matthias

المساهمون: Institute for Molecular Medicine Finland

مصطلحات موضوعية: Extraction, Melanoma, Mutations, Nucleus segmentation, Package, Peptide identification, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: The authors thank M. Ryk ae r, J. Madsen (NNF CPR Mass Spectrometry Platform, University of Copenhagen) and L. Drici (NNF CPR Proteomics Program) as well as J. Mueller (MPIB Munich) for technical assistance. We acknowledge F. Hoffmann, C. Greb and F. Schlaudraff from Leica for technical support; T. Danka and M. Kovacs for fruitful scientific discussions; and T. Hartig Braunstein, P. Hernandez-Varas and C. Prats from the Core Facility of Integrated Microscopy for microscopy support. We thank J. Lukas for scientific support and guidance and J. Percival for the scientific illustrations (Illustration Ltd.). This work was supported by grants from the Novo Nordisk Foundation (grant agreements NNF14CC0001 and NNF15CC0001) and the Max Planck Society for the Advancement of Science and by the Chan Zuckerberg Initiative for partial funding of the cell cycle work (grant CZF2019-002448) to E. Lundberg, M.M. and P.H. F.C. acknowledges the European Union's Horizon 2020 Research and Innovation Programme under grant agreement 846795 (Marie Skodowska-Curie grant) and the German Ministry of Education and Research (BMBF), as part of the National Research Node 'Mass Spectrometry in Systems Medicine' (MSCoreSys), under grant agreement 161L0222. B.D.A. acknowledges support from the Lundbeck Foundation (R252-2017-1414) and the Novo Nordisk Foundation (NNF20OC0065720). P.H., R.H., F.K., E.M. and A.K. acknowledge support from the LENDULET-BIOMAG Grant (2018-342), European Regional Development Funds (GINOP-2.2.1-15-2017-00072), H2020 (ERAPERMED-COMPASS, ERAPERMED-SYMMETRY, DiscovAIR, FAIR-CHARM), OTKA-SNN, TKP2021-EGA09 and ELKH-Excellence grants. E. Lengyel is supported by NIH R35CA264619 and the Chan Zuckerberg Initiative (CZIF2019-002435). We acknowledge S. Ito and H. Masai (Tokyo Metropolitan Institute of Medical Science) for providing the stable U2OS FUCCI cell line. The LCK-GFP plasmid was a gift from S. Green (Addgene, plasmid 61099).; Mund , A , Coscia , F , Kriston , A , Hollandi , R , Kovacs , F , Brunner , A-D , Migh , E , Schweizer , L , Santos , A , Bzorek , M , Naimy , S , Rahbek-Gjerdrum , L M , Dyring-Andersen , B , Bulkescher , J , Lukas , C , Eckert , M A , Lengyel , E , Gnann , C , Lundberg , E , Horvath , P & Mann , M 2022 , ' Deep Visual Proteomics defines single-cell identity and heterogeneity ' , Nature Biotechnology , vol. 40 , no. 8 , pp. 1231–1240 . https://doi.org/10.1038/s41587-022-01302-5Test; 85130484429; e4d67b5c-8197-480f-9696-3ab7ecb6c143; http://hdl.handle.net/10138/354951Test; 000798052500002

الإتاحة: http://hdl.handle.net/10138/354951Test

المؤلفون: Thielert, Marvin, Itang, Ericka C.M., Ammar, Constantin, Rosenberger, Florian A., Bludau, Isabell, Schweizer, Lisa, Nordmann, Thierry M., Skowronek, Patricia, Wahle, Maria, Zeng, Wen Feng, Zhou, Xie Xuan, Brunner, Andreas David, Richter, Sabrina, Levesque, Mitchell P., Theis, Fabian J., Steger, Martin, Mann, Matthias

المصدر: Thielert , M , Itang , E C M , Ammar , C , Rosenberger , F A , Bludau , I , Schweizer , L , Nordmann , T M , Skowronek , P , Wahle , M , Zeng , W F , Zhou , X X , Brunner , A D , Richter , S , Levesque , M P , Theis , F J , Steger , M & Mann , M 2023 , ' Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel ' , Molecular Systems Biology , vol. 19 , ....

مصطلحات موضوعية: DIA, dimethyl labeling, multiplexing, single cells, spatial proteomics

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.15252/msb.202211503Test
https://curis.ku.dk/portal/da/publications/robust-dimethylbased-multiplexdia-doubles-singlecell-proteome-depth-via-a-reference-channelTest(5fe3a36c-ffb6-4c07-a789-6a1022d2917d).html
https://curis.ku.dk/ws/files/380155826/thielert_et_al_2023_robust_dimethyl_based_multiplex_dia_doubles_single_cell_proteome_depth_via_a_reference_channel.pdfTest

المؤلفون: Michaelis, André C, Brunner, Andreas-David, Zwiebel, Maximilian, Meier, Florian, Strauss, Maximilian T, Bludau, Isabell, Mann, Matthias

المصدر: Michaelis , A C , Brunner , A-D , Zwiebel , M , Meier , F , Strauss , M T , Bludau , I & Mann , M 2023 , ' The social and structural architecture of the yeast protein interactome ' , Nature , vol. 624 , no. 7990 , pp. 192-200 . https://doi.org/10.1038/s41586-023-06739-5Test

مصطلحات موضوعية: Mass Spectrometry, Protein Interaction Mapping/methods, Proteome/chemistry, Reproducibility of Results, Saccharomyces cerevisiae/chemistry, Protein Interaction Maps, Saccharomyces cerevisiae Proteins/chemistry, Epigenesis, Genetic, Databases, Factual

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/s41586-023-06739-5Test
https://curis.ku.dk/portal/da/publications/the-social-and-structural-architecture-of-the-yeast-protein-interactomeTest(1f69068c-d42e-43f0-bf6f-dcd8373d1571).html
https://curis.ku.dk/ws/files/379170104/s41586_023_06739_5.pdfTest

المؤلفون: Skowronek, Patricia, Thielert, Marvin, Voytik, Eugenia, Tanzer, Maria C, Hansen, Fynn M, Willems, Sander, Karayel, Ozge, Brunner, Andreas-David, Meier, Florian, Mann, Matthias

المصدر: Skowronek , P , Thielert , M , Voytik , E , Tanzer , M C , Hansen , F M , Willems , S , Karayel , O , Brunner , A-D , Meier , F & Mann , M 2022 , ' Rapid and In-Depth Coverage of the (Phospho-)Proteome With Deep Libraries and Optimal Window Design for dia-PASEF ' , Molecular and Cellular Proteomics , vol. 21 , no. 9 , 100279 . https://doi.org/10.1016/j.mcpro.2022.100279Test

مصطلحات موضوعية: Animals, Chromatography, Liquid/methods, Epidermal Growth Factor, Humans, Mammals/metabolism, Proteome/metabolism, Proteomics/methods, Tandem Mass Spectrometry/methods

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016/j.mcpro.2022.100279Test
https://curis.ku.dk/portal/da/publications/rapid-and-indepth-coverage-of-the-phosphoproteome-with-deep-libraries-and-optimal-window-design-for-diapasefTest(a22049b2-a4ed-47d2-b7b2-ad7dad512b71).html
https://curis.ku.dk/ws/files/321962504/1_s2.0_S1535947622000871_main.pdfTest

المؤلفون: Mund, Andreas, Coscia, Fabian, Kriston, András, Hollandi, Réka, Kovács, Ferenc, Brunner, Andreas-David, Migh, Ede, Schweizer, Lisa, Santos, Alberto, Bzorek, Michael, Naimy, Soraya, Rahbek-Gjerdrum, Lise Mette, Dyring-Andersen, Beatrice, Bulkescher, Jutta, Lukas, Claudia, Eckert, Mark Adam, Lengyel, Ernst, Gnann, Christian, Lundberg, Emma, Horvath, Peter, Mann, Matthias

المصدر: Mund , A , Coscia , F , Kriston , A , Hollandi , R , Kovács , F , Brunner , A-D , Migh , E , Schweizer , L , Santos , A , Bzorek , M , Naimy , S , Rahbek-Gjerdrum , L M , Dyring-Andersen , B , Bulkescher , J , Lukas , C , Eckert , M A , Lengyel , E , Gnann , C , Lundberg , E , Horvath , P & Mann , M 2022 , ' Deep Visual Proteomics defines single-cell identity and heterogeneity ' , Nature ....

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/s41587-022-01302-5Test
https://curis.ku.dk/portal/da/publications/deep-visual-proteomics-defines-singlecell-identity-and-heterogeneityTest(72fa4506-a571-4270-874b-46207187448f).html
https://curis.ku.dk/ws/files/320876948/s41587_022_01302_5.pdfTest

المؤلفون: Brunner, Andreas-David, Thielert, Marvin, Vasilopoulou, Catherine, Ammar, Constantin, Coscia, Fabian, Mund, Andreas, Hoerning, Ole B, Bache, Nicolai, Apalategui, Amalia, Lubeck, Markus, Richter, Sabrina, Fischer, David S, Raether, Oliver, Park, Melvin A, Meier, Florian, Theis, Fabian J, Mann, Matthias

المصدر: Brunner , A-D , Thielert , M , Vasilopoulou , C , Ammar , C , Coscia , F , Mund , A , Hoerning , O B , Bache , N , Apalategui , A , Lubeck , M , Richter , S , Fischer , D S , Raether , O , Park , M A , Meier , F , Theis , F J & Mann , M 2022 , ' Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation ' , Molecular Systems Biology , vol. 18 , no. 3 , e10798 . https://doi.org/10.15252/msb.202110798Test

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.15252/msb.202110798Test
https://curis.ku.dk/portal/da/publications/ultrahigh-sensitivity-mass-spectrometry-quantifies-singlecell-proteome-changes-upon-perturbationTest(8df9085f-3dce-47d6-9ac7-d2f8f489d459).html
https://curis.ku.dk/ws/files/303803791/Molecular_Systems_Biology_2022_Brunner_Ultra_u2010high_sensitivity_mass_spectrometry_quantifies_single_u2010cell_proteome.pdfTest