المؤلفون: Alle, Thibault, Varricchio, Carmine, Yao, Yuemang, Lucero, Bobby, Nzou, Goodwell, Demuro, Stefania, Muench, Megan, Vuong, Khoa D, Oukoloff, Killian, Cornec, Anne-Sophie, Francisco, Karol R, Caffrey, Conor R, Lee, Virginia M-Y, Smith, Amos B, Brancale, Andrea, Brunden, Kurt R, Ballatore, Carlo

المصدر: Journal of Medicinal Chemistry. 66(1)

مصطلحات موضوعية: Neurodegenerative, Alzheimer's Disease, Dementia, Neurosciences, Aging, Acquired Cognitive Impairment, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Brain Disorders, Neurological, Humans, Neurodegenerative Diseases, Pyrimidines, Microtubules, Alzheimer Disease, Tubulin, Structure-Activity Relationship, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7zv2q880Test

المؤلفون: Yao, Yuemang, Muench, Megan, Alle, Thibault, Zhang, Bin, Lucero, Bobby, Perez‐Tremble, Roxanne, McGrosso, Dominic, Newman, Mira, Gonzalez, David J., Lee, Virginia M.‐Y., Ballatore, Carlo, Brunden, Kurt R.

المصدر: Alzheimer's & Dementia ; ISSN 1552-5260 1552-5279

الإتاحة: https://doi.org/10.1002/alz.13875Test

المؤلفون: Lucero, Bobby, Francisco, Karol R., Varricchio, Carmine, Liu, Lawrence J., Yao, Yuemang, Brancale, Andrea, Brunden, Kurt R., Caffrey, Conor R., Ballatore, Carlo

وصف الملف: application/pdf

العلاقة: https://orca.cardiff.ac.uk/id/eprint/166274/1/cmdc.202300656.pdfTest; Lucero, Bobby, Francisco, Karol R., Varricchio, Carmine orcid:0000-0002-1673-4768 orcid:0000-0002-1673-4768, Liu, Lawrence J., Yao, Yuemang, Brancale, Andrea, Brunden, Kurt R., Caffrey, Conor R. and Ballatore, Carlo 2024. Design, synthesis, and evaluation of an anti‐trypanosomal [1,2,4]triazolo[1,5‐ a ]pyrimidine probe for photoaffinity labeling studies. ChemMedChem , e202300656. 10.1002/cmdc.202300656 https://doi.org/10.1002/cmdc.202300656Test file https://orca.cardiff.ac.uk/id/eprint/166274/1/cmdc.202300656.pdfTest

الإتاحة: https://doi.org/10.1002/cmdc.202300656Test
https://orca.cardiff.ac.uk/id/eprint/166274Test/
https://orca.cardiff.ac.uk/id/eprint/166274/1/cmdc.202300656.pdfTest

المؤلفون: Monti, Ludovica, Cornec, Anne-Sophie, Oukoloff, Killian, Kovalevich, Jane, Prijs, Kristen, Alle, Thibault, Brunden, Kurt R, Smith, Amos B, El-Sakkary, Nelly, Liu, Lawrence J, Syed, Ali, Skinner, Danielle E, Ballatore, Carlo, Caffrey, Conor R

المصدر: ACS Infectious Diseases. 7(5)

مصطلحات موضوعية: Rare Diseases, Neurosciences, Orphan Drug, Vector-Borne Diseases, Infectious Diseases, Digestive Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Animals, Humans, Microtubules, Paralysis, Schistosoma mansoni, Structure-Activity Relationship, Schistosomiasis, parasite, drug discovery, tubulin, phenylpyrimidines, structure-activity relationship, structure−activity relationship, Medical Microbiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0jc824t0Test

المؤلفون: Oukoloff, Killian, Nzou, Goodwell, Varricchio, Carmine, Lucero, Bobby, Alle, Thibault, Kovalevich, Jane, Monti, Ludovica, Cornec, Anne-Sophie, Yao, Yuemang, James, Michael J, Trojanowski, John Q, Lee, Virginia M-Y, Smith, Amos B, Brancale, Andrea, Brunden, Kurt R, Ballatore, Carlo

المصدر: Journal of Medicinal Chemistry. 64(2)

مصطلحات موضوعية: Brain Disorders, Aging, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease, Neurosciences, Neurodegenerative, Acquired Cognitive Impairment, Dementia, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Brain, Cell Line, Cells, Cultured, Computer Simulation, Humans, Mice, Mice, Transgenic, Microtubules, Models, Molecular, Molecular Docking Simulation, Neurodegenerative Diseases, Neurons, Pyrimidines, Rats, Structure-Activity Relationship, Tauopathies, Triazoles, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/77q8d7tpTest

المؤلفون: Yao, Yuemang, Nzou, Goodwell, Alle, Thibault, Tsering, Wangchen, Maimaiti, Shaniya, Trojanowski, John Q, Lee, Virginia M‐Y, Ballatore, Carlo, Brunden, Kurt R

المصدر: Alzheimer's & Dementia. 16(10)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Biological Psychology, Clinical Sciences, Neurosciences, Psychology, Alzheimer's Disease, Dementia, Neurodegenerative, Acquired Cognitive Impairment, Aging, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Aetiology, Underpinning research, 2.1 Biological and endogenous factors, Development of treatments and therapeutic interventions, 1.1 Normal biological development and functioning, 5.1 Pharmaceuticals, Neurological, Amyloid beta-Peptides, Animals, Axons, Brain, Disease Models, Animal, Female, Humans, Hydrocarbons, Halogenated, Male, Mice, Mice, Transgenic, Microtubules, Plaque, Amyloid, Triazoles, amyloid, axonal transport, microtubules, plaques, therapeutic, Geriatrics, Clinical sciences, Biological psychology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/06s8180jTest

المؤلفون: Oukoloff, Killian, Lucero, Bobby, Francisco, Karol R, Brunden, Kurt R, Ballatore, Carlo

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Animals, Chemistry, Pharmaceutical, Drug Design, Humans, Neoplasms, Parasitic Diseases, Pyrimidines, Structure-Activity Relationship, Triazoles, 1, 2, 4-triazolo[1, 5-a]pyrimidine, Heterocyclic chemistry, Medicinal chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2jq8s6mpTest

المؤلفون: Zhang, Bin, Yao, Yuemang, Cornec, Anne-Sophie, Oukoloff, Killian, James, Michael J, Koivula, Pyry, Trojanowski, John Q, Smith, Amos B, Lee, Virginia M-Y, Ballatore, Carlo, Brunden, Kurt R

المصدر: Molecular Neurodegeneration. 13(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Rare Diseases, Neurodegenerative, Brain Disorders, Neurosciences, Aging, Alzheimer's Disease Related Dementias (ADRD), Dementia, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Alzheimer's Disease, Frontotemporal Dementia (FTD), Aetiology, 2.1 Biological and endogenous factors, Neurological, Alzheimer Disease, Animals, Axonal Transport, Axons, Brain, Disease Models, Animal, Humans, Mice, Microtubules, Neurons, Quinazolines, Tauopathies, Triazoles, tau Proteins, Microtubule, Tauopathy, Therapeutic, Alzheimer's disease, Alzheimer’s disease, Genetics, Clinical Sciences, Neurology & Neurosurgery, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3m84b1gtTest

المؤلفون: Monti, Ludovica, Wang, Steven C, Oukoloff, Killian, Smith, Amos B, Brunden, Kurt R, Caffrey, Conor R, Ballatore, Carlo

المصدر: ChemMedChem. 13(17)

مصطلحات موضوعية: Neurosciences, Vector-Borne Diseases, Rare Diseases, Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Good Health and Well Being, Brain, Dose-Response Relationship, Drug, Humans, Microtubules, Molecular Structure, Parasitic Sensitivity Tests, Pyrimidines, Structure-Activity Relationship, Trypanocidal Agents, Trypanosoma brucei brucei, Trypanosomiasis, African, human African trypanosomiasis, microtubules, phenylpyrimidines, triazolopyrimidines, Trypanosoma brucei, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7hs264h0Test

المؤلفون: Monti, Ludovica, Liu, Lawrence J., Varricchio, Carmine, Lucero, Bobby, Alle, Thibault, Yang, Wenqian, Ben‐Shalom, Ido, Gilson, Michael, Brunden, Kurt R., Brancale, Andrea, Caffrey, Conor R., Ballatore, Carlo

المساهمون: National Institutes of Health

المصدر: ChemMedChem ; volume 18, issue 20 ; ISSN 1860-7179 1860-7187

الإتاحة: https://doi.org/10.1002/cmdc.202300193Test