نتائج البحث - "Broad, Lisa M"

1

دورية أكاديمية

TRPA1 Antagonist LY3526318 Inhibits the Cinnamaldehyde-Evoked Dermal Blood Flow Increase:Translational Proof of Pharmacology

المؤلفون: Bamps, Dorien, Blockeel, Anthony James, Dreesen, Erwin, Marynissen, Heleen, Laenen, Jolien, Hecken, Anne Van, Wilke, August, Shahabi, Shahram, Johnson, Kirk W., Collins, Emily Catherine, Broad, Lisa M., Phillips, Keith G., Hoon, Jan de

المصدر: Bamps , D , Blockeel , A J , Dreesen , E , Marynissen , H , Laenen , J , Hecken , A V , Wilke , A , Shahabi , S , Johnson , K W , Collins , E C , Broad , L M , Phillips , K G & Hoon , J D 2023 , ' TRPA1 Antagonist LY3526318 Inhibits the Cinnamaldehyde-Evoked Dermal Blood Flow Increase : Translational Proof of Pharmacology ' , Clinical Pharmacology & Therapeutics , vol. 114 , no. 5 , pp. 1093-1103 . https://doi.org/10.1002/cpt.3024Test

العلاقة: https://research-information.bris.ac.uk/en/publications/bb7387d2-40c7-4955-9903-7205a917eabcTest

الإتاحة: https://doi.org/10.1002/cpt.3024Test
https://hdl.handle.net/1983/bb7387d2-40c7-4955-9903-7205a917eabcTest
https://research-information.bris.ac.uk/en/publications/bb7387d2-40c7-4955-9903-7205a917eabcTest

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2

دورية أكاديمية

The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

المؤلفون: Thompson, Karen J., Watson, Sonia, Zanato, Chiara, Dall'Angelo, Sergio, De Nooij, Joriene C., Pace‐Bonello, Bethany, Shenton, Fiona C., Sanger, Helen E., Heinz, Beverly A., Broad, Lisa M., Grosjean, Noelle, McQuillian, Jessica R., Dubini, Marina, Pyner, Susan, Greig, Iain, Zanda, Matteo, Bleakman, David, Banks, Robert W., Bewick, Guy S.

المصدر: Experimental Physiology ; volume 109, issue 1, page 81-99 ; ISSN 0958-0670 1469-445X

الإتاحة: https://doi.org/10.1113/ep090761Test

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3

دورية أكاديمية

The atypical 'hippocampal' glutamate receptor coupled to phospholipase D that controls stretch-sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

المؤلفون: Thompson, Karen J, Watson, Sonia, Zanato, Chiara, Dall'Angelo, Sergio, De Nooij, Joriene C, Pace-Bonello, Bethany, Shenton, Fiona C, Sanger, Helen E, Heinz, Beverly A, Broad, Lisa M, Grosjean, Noelle, McQuillian, Jessica R, Dubini, Marina, Pyner, Susan, Greig, Iain, Zanda, Matteo, Bleakman, David, Banks, Robert W, Bewick, Guy S

المساهمون: University of Aberdeen.Institute of Medical Sciences, University of Aberdeen.Medicine, Medical Sciences & Nutrition, University of Aberdeen.Medical Sciences, University of Aberdeen.Medical Sciences - Cardiovascular Group, University of Aberdeen.Neuroscience

مصطلحات موضوعية: GluK2, glutamate receptor, Karinate receptor, mechanosensation, muscle spindle, PLD-mGluR, R Medicine, Supplementary Data

وصف الملف: application/pdf

العلاقة: Experimental Physiology; 280659594; 566a2bed-8102-4d15-a436-6b9100dc6b7a; 85169590433; Thompson , K J , Watson , S , Zanato , C , Dall'Angelo , S , De Nooij , J C , Pace-Bonello , B , Shenton , F C , Sanger , H E , Heinz , B A , Broad , L M , Grosjean , N , McQuillian , J R , Dubini , M , Pyner , S , Greig , I , Zanda , M , Bleakman , D , Banks , R W & Bewick , G S 2024 , ' The atypical 'hippocampal' glutamate receptor coupled to phospholipase D that controls stretch-sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2 ' , Experimental Physiology , vol. 109 , no. 1 , pp. 81-99 . https://doi.org/10.1113/EP090761Test; ORCID: /0000-0001-8266-7797/work/141718571; ORCID: /0000-0003-0603-3383/work/141722981; https://hdl.handle.net/2164/21615Test

الإتاحة: https://doi.org/10.1113/EP090761Test
https://hdl.handle.net/2164/21615Test

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النص الكامل

4

دورية أكاديمية

TRPA1 Antagonist LY3526318 Inhibits the Cinnamaldehyde‐Evoked Dermal Blood Flow Increase: Translational Proof of Pharmacology.

المؤلفون: Bamps, Dorien, Blockeel, Anthony James, Dreesen, Erwin, Marynissen, Heleen, Laenen, Jolien, Van Hecken, Anne, Wilke, August, Shahabi, Shahram, Johnson, Kirk W., Collins, Emily Catherine, Broad, Lisa M., Phillips, Keith G., de Hoon, Jan

المصدر: Clinical Pharmacology & Therapeutics; Nov2023, Vol. 114 Issue 5, p1093-1103, 11p

مصطلحات موضوعية: TOPICAL drug administration, BLOOD flow, PHARMACOLOGY, ION channels, SENSORY neurons, VASODILATION

5

دورية أكاديمية

From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease

المؤلفون: Brown, Alastair J.H., Bradley, Sophie J., Marshall, Fiona H., Brown, Giles A., Bennett, Kirstie A., Brown, Jason, Cansfield, Julie E., Cross, David M., de Graaf, Chris, Hudson, Brian D., Dwomoh, Louis, Dias, João M., Errey, James C., Hurrell, Edward, Liptrot, Jan, Mattedi, Giulio, Molloy, Colin, Nathan, Pradeep J., Okrasa, Krzysztof, Osborne, Greg, Patel, Jayesh C., Pickworth, Mark, Robertson, Nathan, Shahabi, Shahram, Bundgaard, Christoffer, Phillips, Keith, Broad, Lisa M., Goonawardena, Anushka V., Morairty, Stephen R., Browning, Michael, Perini, Francesca, Dawson, Gerard R., Deakin, John F.W., Smith, Robert T., Sexton, Patrick M., Warneck, Julie, Vinson, Mary, Tasker, Tim, Tehan, Benjamin G., Teobald, Barry, Christopoulos, Arthur, Langmead, Christopher J., Jazayeri, Ali, Cooke, Robert M., Rucktooa, Prakash, Congreve, Miles S., Weir, Malcolm, Tobin, Andrew B.

المصدر: Cell ; volume 184, issue 24, page 5886-5901.e22 ; ISSN 0092-8674

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.cell.2021.11.001Test
https://api.elsevier.com/content/article/PII:S0092867421013167?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0092867421013167?httpAccept=text/plainTest

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6

دورية أكاديمية

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

المصدر: Bradley , S J , Molloy , C , Valuskova , P , Dwomoh , L , Scarpa , M , Rossi , M , Finlayson , L , Svensson , K A , Chernet , E , Barth , V N , Gherbi , K , Sykes , D A , Wilson , C A , Mistry , R , Sexton , P M , Christopoulos , A , Mogg , A J , Rosethorne , E M , Sakata , S , John Challiss , R A , Broad , L M & Tobin , A B ....

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/s41589-019-0453-9Test
https://research.monash.edu/en/publications/058d33c9-f7cd-4629-8d49-734ac1cf3563Test
https://researchmgt.monash.edu/ws/files/300514506/300512608_oa.pdfTest
http://www.scopus.com/inward/record.url?scp=85079780292&partnerID=8YFLogxKTest

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7

دورية أكاديمية

Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes

المؤلفون: Bradley, Sophie J., Molloy, Colin, Bundgaard, Christoffer, Mogg, Adrian J., Thompson, Karen J., Dwomoh, Louis, Sanger, Helen E., Crabtree, Michael D., Brooke, Simon M., Sexton, Patrick M., Felder, Christian C., Christopoulos, Arthur, Broad, Lisa M., Tobin, Andrew B., Langmead, Christopher J.

وصف الملف: text

العلاقة: http://eprints.gla.ac.uk/160565/1/160565.pdfTest; Bradley, S. J. et al. (2018) Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes. Molecular Pharmacology , 93(6), pp. 645-656. (doi:10.1124/mol.118.111872 ) (PMID:29695609) (PMCID:PMC5963591)

الإتاحة: https://doi.org/10.1124/mol.118.111872Test
http://eprints.gla.ac.uk/160565Test/
http://eprints.gla.ac.uk/160565/1/160565.pdfTest

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8

دورية أكاديمية

Bitopic binding mode of an M 1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes S

المؤلفون: Bradley, Sophie J., Molloy, Colin, Bundgaard, Christoffer, Mogg, Adrian J., Thompson, Karen J., Dwomoh, Louis, Sanger, Helen E., Crabtree, Michael D., Brooke, Simon M., Sexton, Patrick M., Felder, Christian C., Christopoulos, Arthur, Broad, Lisa M., Tobin, Andrew B., Langmead, Christopher J.

المصدر: Bradley , S J , Molloy , C , Bundgaard , C , Mogg , A J , Thompson , K J , Dwomoh , L , Sanger , H E , Crabtree , M D , Brooke , S M , Sexton , P M , Felder , C C , Christopoulos , A , Broad , L M , Tobin , A B & Langmead , C J 2018 , ' Bitopic binding mode of an M 1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes S ' , Molecular Pharmacology , vol. 93 , ....

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1124/mol.118.111872Test
https://research.monash.edu/en/publications/19826e16-5eb3-4457-9b36-2b1b13a92392Test
https://researchmgt.monash.edu/ws/files/279073426/256536510_oa.pdfTest
http://www.scopus.com/inward/record.url?scp=85052534454&partnerID=8YFLogxKTest

View record in BASE