المؤلفون: Konermann, Silvana, Brigham, Mark D, Trevino, Alexandro E, Joung, Julia, Abudayyeh, Omar O, Barcena, Clea, Hsu, Patrick D, Habib, Naomi, Gootenberg, Jonathan S, Nishimasu, Hiroshi, Nureki, Osamu, Zhang, Feng

المصدر: Nature. 517(7536)

مصطلحات موضوعية: Genetics, Biotechnology, Human Genome, Cancer, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, CRISPR-Associated Proteins, CRISPR-Cas Systems, Cell Line, Tumor, Clustered Regularly Interspaced Short Palindromic Repeats, DNA, Complementary, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, Gene Library, Genetic Engineering, Genetic Loci, Genetic Testing, Genome, Human, Humans, Indoles, Melanoma, Proto-Oncogene Proteins B-raf, RNA, Untranslated, Reproducibility of Results, Sulfonamides, Transcriptional Activation, Up-Regulation, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5hb3n5ghTest

المؤلفون: Konermann, Silvana, Brigham, Mark D, Trevino, Alexandro E, Hsu, Patrick D, Heidenreich, Matthias, Le Cong, Platt, Randall J, Scott, David A, Church, George M, Zhang, Feng

المصدر: Nature. 500(7463)

مصطلحات موضوعية: Genetics, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Animals, Arabidopsis Proteins, Basic Helix-Loop-Helix Transcription Factors, Cells, Cultured, Chromatin, Cryptochromes, Epigenesis, Genetic, Gene Expression Regulation, Genetic Vectors, Light, Male, Mice, Mice, Inbred C57BL, Neurons, Optogenetics, Time Factors, Transcription, Genetic, Two-Hybrid System Techniques, Wakefulness, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4mn6d7gzTest

المؤلفون: Li, Justin W., Yin, David, Wang, Zheng, Brigham, Mark D., LaMoreaux, Brian D., Kent, Jeffrey D., Francis-Sedlak, Megan, Johnson, Richard J., Hadker, Nandini, Francis, Kevin M., Sanchez, Herman A., Miyasato, Gavin

المصدر: Transplantation Direct ; volume 6, issue 12, page e634 ; ISSN 2373-8731

الإتاحة: https://doi.org/10.1097/txd.0000000000001081Test

المؤلفون: Tekin, Halil, Anaya, Michael, Brigham, Mark D, Nauman, Claire, Langer, Robert, Khademhosseini, Ali

المساهمون: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology. Department of Chemical Engineering, Harvard University--MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology. Department of Biology

المصدر: PMC

وصف الملف: application/pdf

العلاقة: Lab on a Chip; https://hdl.handle.net/1721.1/134500Test; Tekin, H., et al. "Stimuli-Responsive Microwells for Formation and Retrieval of Cell Aggregates." Lab on a Chip 10 18 (2010): 2411-18.

الإتاحة: https://hdl.handle.net/1721.1/134500Test

المؤلفون: Church, George M., Konermann, Silvana M, Brigham, Mark D, Trevino, Alexandro E., Hsu, Patrick, Heidenreich, Matthias, Cong, Le, Platt, Randall Jeffrey, Scott, David Arthur, Zhang, Feng

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research at MIT, Konermann, Silvana M, Brigham, Mark D, Trevino, Alexandro E., Hsu, Patrick, Heidenreich, Matthias, Cong, Le, Platt, Randall Jeffrey, Scott, David Arthur, Zhang, Feng

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038Test; Nature; http://hdl.handle.net/1721.1/112726Test; Konermann, Silvana et al. "Optical control of mammalian endogenous transcription and epigenetic states." Nature 419 (October 2002): 456-459; orcid:0000-0001-7915-1685; orcid:0000-0002-2639-9879; orcid:0000-0003-2782-2509

الإتاحة: http://hdl.handle.net/1721.1/112726Test

المؤلفون: Joung, Julia, Konermann, Silvana, Gootenberg, Jonathan S, Abudayyeh, Omar O, Platt, Randall J, Brigham, Mark D, Sanjana, Neville E, Zhang, Feng

المصدر: Nature Protocols ; volume 14, issue 7, page 2259-2259 ; ISSN 1754-2189 1750-2799

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1038/s41596-018-0063-0Test
http://www.nature.com/articles/s41596-018-0063-0.pdfTest
http://www.nature.com/articles/s41596-018-0063-0Test

المؤلفون: Alford, Patrick W., Dabiri, Borna E., Goss, Josue A., Hemphill, Matthew A., Brigham, Mark D., Parker, Kevin Kit

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2011 Aug 01. 108(31), 12705-12710.

الوصول الحر: https://www.jstor.org/stable/27979075Test

المؤلفون: Joung, Julia, Konermann, Silvana, Gootenberg, Jonathan S., Abudayyeh, Omar O., Platt, Randall, id_orcid:0 000-0002-2914-7052, Brigham, Mark D., Sanjana, Neville E., Zhang, Feng

المصدر: bioRxiv

وصف الملف: application/application/pdf

العلاقة: http://hdl.handle.net/20.500.11850/127003Test

الإتاحة: https://doi.org/20.500.11850/127003Test
https://doi.org/10.3929/ethz-b-000127003Test
https://doi.org/10.1101/059626Test
https://hdl.handle.net/20.500.11850/127003Test

المؤلفون: Li, Justin W., Suh, Marissa, Brigham, Mark D., Kent, Jeffrey D., LaMoreaux, Brian, Johnson, Richard J., Mandell, Brian F., Hadker, Nandini, Sanchez, Herman, Francis, Kevin, Miyasato, Gavin

مصطلحات موضوعية: Original Paper, demo, envir

العلاقة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177036Test/

الإتاحة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177036Test/