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1دورية أكاديمية
المؤلفون: Xiaoyu Zhang (62901), Lena M. Luukkonen (10499083), Christie L. Eissler (10499086), Vincent M. Crowley (4419007), Yu Yamashita (1421008), Michael A. Schafroth (1771792), Shota Kikuchi (8968940), David S. Weinstein (2123176), Kent T. Symons (2252773), Brian E. Nordin (10499089), Joe L. Rodriguez (10499092), Thomas G. Wucherpfennig (10499095), Ludwig G. Bauer (10499098), Melissa M. Dix (1616689), Dean Stamos (1600186), Todd M. Kinsella (10499101), Gabriel M. Simon (131638), Kristen A. Baltgalvis (10499104), Benjamin F. Cravatt (93774)
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Electrophilic Proteolysis-Targeting., E 3-binding compounds, prostate cancer cells, Targeted Protein Degradation, ligand-induced protein degradation, E 3 ligase substrate adaptor, DCAF 11-directed electrophilic PROTACs, E 3 ligase, support ligand-induced protein degr., E 3 ligases, candidate electrophilic PROTACs, FBKP, electrophilic PROTACs act, DCAF 11
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المؤلفون: Kristen A. Baltgalvis, Vincent M. Crowley, Michael A. Schafroth, Brian E. Nordin, Benjamin F. Cravatt, Christie L Eissler, Joe L Rodriguez, Shota Kikuchi, Xiaoyu Zhang, Thomas G Wucherpfennig, Todd Kinsella, Kent T Symons, Melissa M. Dix, David S. Weinstein, Dean Stamos, Gabriel M. Simon, Yu Yamashita, Ludwig Bauer, Lena M Luukkonen
المصدر: J Am Chem Soc
مصطلحات موضوعية: Male, Proteasome Endopeptidase Complex, Proteolysis, Protein degradation, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Catalysis, Chimera (genetics), Colloid and Surface Chemistry, Cell Line, Tumor, medicine, Humans, Receptor, medicine.diagnostic_test, biology, Ubiquitin, Chemistry, Prostatic Neoplasms, Ubiquitin-Protein Ligase Complexes, General Chemistry, 0104 chemical sciences, Ubiquitin ligase, Cell biology, Androgen receptor, Receptors, Androgen, Cell culture, Cancer cell, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9801b3a3bafd3e374259ca9ad1a1524Test
https://doi.org/10.1021/jacs.1c00990Test -
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المؤلفون: Tsuyoshi Imasaki, Patrick Baumann, Claudine Bisson, Ashish Radadiya, Yuichiro Takagi, David W. Rice, Svetlana E. Sedelnikova, Nigel G. J. Richards, Adriana Coricello, Tyzoon K. Nomanbhoy, Alexandria H. Berry, Sabine Wenzel, John W. Kozarich, Yi Jin, Brian E. Nordin, Wen Zhu, Francisco Martínez-Márquez
المصدر: Communications Biology, Vol 2, Iss 1, Pp 1-14 (2019)
Communications Biologyمصطلحات موضوعية: Asparagine synthetase, Medicine (miscellaneous), High resolution, Medicinal chemistry, Crystal structure, Article, General Biochemistry, Genetics and Molecular Biology, Metastasis, 03 medical and health sciences, 0302 clinical medicine, medicine, Computational models, lcsh:QH301-705.5, Binding selectivity, X-ray crystallography, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, medicine.disease, In vitro, Enzymes, 3. Good health, Enzyme, chemistry, Biochemistry, lcsh:Biology (General), 030220 oncology & carcinogenesis, General Agricultural and Biological Sciences, Selectivity
وصف الملف: application/pdf; application/msword; application/vnd.ms-excel
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b6e17ac46e2600532640cbb5658656Test
http://link.springer.com/article/10.1038/s42003-019-0587-zTest -
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المؤلفون: Tyzoon K. Nomanbhoy, Sabine Wenzel, Alexandria H. Berry, Brian E. Nordin, Nigel G. J. Richards, Tsuyoshi Imasaki, David W. Rice, Claudine Bisson, Wen Zhu, Francisco Martínez-Márquez, Adriana Coricello, Patrick Baumann, Yuichiro Takagi, Ashish Radadiya, John W. Kozarich, Svetlana E. Sedelnikova, Yi Jin
المصدر: Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-1 (2019)مصطلحات موضوعية: 0303 health sciences, Chemistry, Asparagine synthetase, Medicine (miscellaneous), High resolution, Medicinal chemistry, Crystal structure, Combinatorial chemistry, General Biochemistry, Genetics and Molecular Biology, Enzymes, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, lcsh:Biology (General), 030220 oncology & carcinogenesis, X-ray crystallography, Computational models, Author Correction, General Agricultural and Biological Sciences, Selectivity, lcsh:QH301-705.5, 030304 developmental biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7376b0d7f72c77cf8ba5e0a0098265fTest
https://doi.org/10.1038/s42003-019-0690-1Test -
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المؤلفون: Wen Zhu, Brian E. Nordin, John W. Kozarich, David W. Rice, Yi Jin, Svetlana E. Sedelnikova, Nigel G. J. Richards, Yuichiro Takagi, Sabine Wenzel, Claudine Bisson, Ashish Radadiya, Alexandria H. Berry, Patrick Baumann, Tsuyoshi Imasaki, Tyzoon K. Nomanbhoy
مصطلحات موضوعية: Cell lysates, chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Chemistry, Asparagine synthetase, Drug target, Cancer therapy, Tumor cells, medicine.disease, 01 natural sciences, 0104 chemical sciences, 3. Good health, Metastasis, 03 medical and health sciences, Enzyme, Biochemistry, medicine, Cell permeability, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278fe1ec095c7d5883329324ce978eb5Test
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المؤلفون: Christie L Eissler, Todd Kinsella, Gabe Simon, Colin Walsh, Joseph Klebba, Joel Chick, Ali Tabatabaei, Lena M Luukkonen, Landon Whitby, Kent T Symons, Kristen A. Baltgalvis, Yuta Naro, Matthew P. Patricelli, Larry Burgess, Dean Stamos, Joon Chang, Shota Kikuchi, Jaclyn Brannon, Charles Chapman, Brian E. Nordin
المصدر: Cancer Research. 80:6411-6411
مصطلحات موضوعية: Cancer Research, biology, Chemistry, Computational biology, Protein degradation, Proteomics, Small molecule, Ubiquitin ligase, Oncology, Tissue expression, Covalent bond, biology.protein, Catalytic efficiency, Cullin
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0fd8700abc857dc43915d725ae6b6f54Test
https://doi.org/10.1158/1538-7445.am2020-6411Test -
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المؤلفون: Helge Weissig, Nathanael S. Gray, Chris Herring, Arwin Aban, David Zhou, Heidi E. Brown, Eric Okerberg, Subadhra Jagannathan, John W. Kozarich, Qingkai Yang, Jianming Zhang, Jiing Dwan Lee, Tyzoon K. Nomanbhoy, Jiangyue Wu, Brian E. Nordin, Matthew P. Patricelli
المصدر: Chemistry & Biology. 18:699-710
مصطلحات موضوعية: Clinical Biochemistry, Dasatinib, MAP Kinase Kinase 5, Mitogen-activated protein kinase kinase, Biochemistry, Article, Adenosine Triphosphate, Cell Line, Tumor, Drug Discovery, Humans, ASK1, c-Raf, Protein Kinase Inhibitors, Molecular Biology, Pharmacology, MAP kinase kinase kinase, biology, Cyclin-dependent kinase 2, General Medicine, Recombinant Proteins, Cell biology, Thiazoles, Pyrimidines, Mitogen-activated protein kinase, biology.protein, Molecular Medicine, raf Kinases, Cyclin-dependent kinase 9, Kinase binding, Protein Kinases, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf88204473b0d9c9c120755dfc9e3bdTest
https://doi.org/10.1016/j.chembiol.2011.04.011Test -
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المؤلفون: Steve J. Brown, Frank J. Schoenen, Peter Chase, Brian E. Nordin, Brian M. Stoltz, Dmitriy Minond, Amanda C. Jones, Hugh Rosen, Kelin Li, Tsui-Fen Chou, Patrick Porubsky, Peter Hodder, Raymond J. Deshaies, Matthew P. Patricelli
المصدر: Proceedings of the National Academy of Sciences. 108:4834-4839
مصطلحات موضوعية: Proteasome Endopeptidase Complex, ATPase, Autophagosome maturation, Antineoplastic Agents, Endoplasmic Reticulum, Cell Line, Mice, Ubiquitin, RNA interference, Neoplasms, Autophagy, medicine, Animals, Humans, Enzyme Inhibitors, Adenosine Triphosphatases, Caspase 7, Multidisciplinary, biology, Caspase 3, Nuclear Proteins, Biological Sciences, Cell biology, Biochemistry, Proteasome, Cancer cell, Quinazolines, biology.protein, Proteasome inhibitor, medicine.drug
وصف الملف: application/pdf; application/vnd.ms-excel
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c223f363522a902a0174c1acbee8e9aTest
https://doi.org/10.1073/pnas.1015312108Test -
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المؤلفون: Brian E. Nordin, Valérie de Crécy-Lagard, Benjamin J. Lyons, Paul Schimmel, James R. Williamson, Yulien Cruz, Basma El Yacoubi, Manal A. Swairjo, Robert Reddy, Fabio Agnelli
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Adenosine, Saccharomyces cerevisiae Proteins, Protein family, Saccharomyces cerevisiae, Molecular Sequence Data, RNA-binding protein, Biology, medicine.disease_cause, Ribosome, Genome, 03 medical and health sciences, Adenosine Triphosphate, RNA, Transfer, Genetics, medicine, Amino Acid Sequence, Escherichia coli, Gene, 030304 developmental biology, RNA, Transfer, Thr, 0303 health sciences, Genes, Essential, Escherichia coli Proteins, 030302 biochemistry & molecular biology, RNA-Binding Proteins, Genomics, biology.organism_classification, DNA-Binding Proteins, Transfer RNA, RNA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462fedc0ed71f14b7d5755f39e5d6d52Test
http://europepmc.org/articles/PMC2685093Test -
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المؤلفون: Anna Hainley, Jiangyue Wu, Brian E. Nordin, Tyzoon K. Nomanbhoy, Yongsheng Liu, Jonathan S. Rosenblum, Heidi E. Brown, Arwin Aban, John W. Kozarich
المصدر: Biochemistry. 54(19)
مصطلحات موضوعية: biology, Kinase, ATPase, Biochemistry, Hsp90, Radicicol, Hsp90 inhibitor, Cell Line, chemistry.chemical_compound, Adenosine Triphosphate, chemistry, Tandem Mass Spectrometry, Chaperone (protein), biology.protein, Native state, Humans, Chemoproteomics, HSP90 Heat-Shock Proteins, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc3e6114285cf11b7c39bf07a902aa8Test
https://pubmed.ncbi.nlm.nih.gov/25905789Test