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1دورية أكاديمية
المؤلفون: Christian J. Bettencourt (14252613), Tanja Krainz (3105696), Sharon Chow (2162938), Brendan T. Parr (2342548), William F. Tracy (5685083), Paul V. Bernhardt (1435054), Huw M. L. Davies (8082566), Craig M. Williams (1939036)
مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Immunology, Biological Sciences not elsewhere classified, zwitterionic rearrangement pathways, structurally diverse carbocyclic, model alkenyl donor, wide selection, triazole probe, products obtained, opened products, n <, investigation unearthed, highly dependent, furan substrate, excellent yields, electronic features, >‑ sulfonyl, >- sulfonyltriazole
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2دورية أكاديمية
المؤلفون: Sharada S. Labadie (1970821), Karine Thai (11217276), Jessica M. Grandner (4500067), Yanzhou Liu (1503178), Brendan T. Parr (2342548)
مصطلحات موضوعية: Biophysics, Biochemistry, Neuroscience, Physiology, Infectious Diseases, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, amine, proceed, cyclization, exo-trig ring closure, six-membered, pyridone, enyne amides, ring closure reaction
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3دورية أكاديمية
المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers
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4
المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers
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5
المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers
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6
المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers
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7دورية أكاديمية
المؤلفون: Malcolm P. Huestis (10493092), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Joachim Rudolph (1464982), Michael Siu (1503160)
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Developmental Biology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, Pyridopyridazinone pan-RAF Kinase I., kinase-selective RAF inhibitors, HCT 116 xenograft mouse model, Targeting KRAS Mutant Cancers, MEK inhibitor cobimetinib, Type II pan-RAF inhibitor GNE -9815, GNE -9815, MAPK pathway modulation, aryl urea RAF inhibitors